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971.
L. Prech Z. Nemecek J.
afrnkov J.
imunek V. Truhlík N. M. Shutte 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1995,15(12):33-36
The paper is based on the electron and ion energy spectra measurement on board the main spacecraft of the APEX mission. During the active phase of the experiment an intense electron beam was emitted from the main satellite. The basic cycle of the electron injection is formed by current pulses of different frequencies, duration and intensity. The spacecraft potential changes due to the gun operation were compensated by a low energy Xe plasma generator. The data show that the response of the environment to the beam emission depends not only on injection parameters but on the spacecraft position and orientation with respect to the magnetic field as well. The typical response is an increase of the intensity of the low energy (less than 1 keV) electrons in all directions. In addition, strong field aligned fluxes of electrons and/or ions are observed with energies below the gun energy. An attempt to classify different types of response and to find possible mechanisms which can explain the observed phenomena is made in the present paper. 相似文献
972.
DNA fragmentation by charged particle tracks. 总被引:1,自引:0,他引:1
B Stenerlow E Hoglund J Carlsson 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2002,30(4):859-863
High-LET (linear energy transfer) charged particles induce DNA double-strand breaks (DSB) in a non-random fashion in mammalian cells. The clustering of DSB, probably determined by track structure as well as chromatin conformation, results in an excess of small- and intermediate-sized DNA fragments. DNA fragmentation in normal human fibroblasts (GM5758) was analyzed by pulsed-field gel electrophoresis after irradiation with photons (60Co) or 125 keV/micrometers nitrogen ions. Compared to conventional DSB analysis, i.e. assays only measuring the fraction of DNA smaller than a single threshold, the relative biological effectiveness (RBE) for DSB induction increased with 100%. Further, the size distribution of DNA fragments showed a significant dependence on radiation quality, with an excess of fragments up to 1 Mbp. Irradiation of naked genomic DNA without histone proteins increased the DSB yields 25 and 13 times for photons and nitrogen ions, respectively. The results suggest possible roles of both track structure and chromatin organization in the distribution of DNA double-strand breaks along the chromosome. 相似文献
973.
Lombardo P. Macri Pellizzeri T. 《IEEE transactions on aerospace and electronic systems》2002,38(4):1256-1275
Deals with multitemporal sequences of synthetic aperture radar (SAR) images with regions possibly affected by step reflectivity patterns of change. Specifically, it addresses the problems of detecting a temporal step pattern with small reflectivity change against a constant pattern and of estimating the transition instant for the step. The statistically optimized signal processing techniques proposed in this work are most appropriate for the new generation of SAR systems with high revisit time that are currently under development. We propose two different techniques, based on the maximum likelihood (ML) approach, that make different use of prior knowledge on the radar cross section (RCS) levels of the searched pattern. They process the whole sequence to achieve optimal discrimination capability between regions affected and not affected by a step change and optimal estimation accuracy for the step transition instant. The first technique (known step pattern (KSP)-detector) assumes complete knowledge of the RCS levels of the searched pattern of change, while the second one (USP-detector) is based on the assumption of totally unknown step pattern. 相似文献
974.
975.
R J White J B Bassingthwaighte J B Charles M J Kushmerick D J Newman 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2003,31(1):7-16
Today, the tools are in our hands to enable us to travel away from our home planet and become citizens of the solar system. Even now, we are seriously beginning to develop the robust infrastructure that will make the 21st century the Century of Space Travel. But this bold step must be taken with due concern for the health, safety and wellbeing of future space explorers. Our long experience with space biomedical research convinces us that, if we are to deal effectively with the medical and biomedical issues of exploration, then dramatic and bold steps are also necessary in this field. We can no longer treat the human body as if it were composed of muscles, bones, heart and brain acting independently. Instead, we must lead the effort to develop a fully integrated view of the body, with all parts connected and fully interacting in a realistic way. This paper will present the status of current (2000) plans by the National Space Biomedical Research Institute to initiate research in this area of integrative physiology and medicine. Specifically, three example projects are discussed as potential stepping stones towards the ultimate goal of producing a digital human. These projects relate to developing a functional model of the human musculoskeletal system and the heart. 相似文献
976.
N Stromgren Allen P Chattaraj D Collings E Johannes 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2003,32(8):1631-1637
In Zea mays L., changes in orientation of stems are perceived by the pulvinal tissue, which responds to the stimulus by differential growth resulting in upward bending of the stem. Gravity is perceived in the bundle sheath cells, which contain amyloplasts that sediment to the new cell base when a change in the gravity vector occurs. The mechanism by which the mechanical signal is transduced into a physiological response is so far unknown for any gravity perceiving tissue. It is hypothesized that this involves interactions of amyloplasts with the plasma membrane and/or ER via cytoskeletal elements. To gain further insights into this process we monitored amyloplast movements in response to gravistimulation. In a pharmacological approach we investigated how the dynamics of plastid sedimentation are affected by actin and microtubule (MT) disrupting drugs. Dark grown caulonemal filaments of the moss Physcomitrella patens respond to gravity vector changes with a reorientation of tip growth away from the gravity vector. MT distributions in tip cells were monitored over time and MTs were seen to accumulate preferentially on the lower flank of the tip 30 min after a 90 degree turn. Using a self-referencing Ca2+ selective ion probe, we found that growing caulonemal filaments exhibit a Ca2+ influx at the apical dome, similar to that reported previously for other tip growing cells. However, in gravistimulated Physcomitrella filaments the region of Ca2+ influx is not confined to the apex, but extends about 60 micrometers along the upper side of the filament. Our results indicate an asymmetry in the Ca2+ flux pattern between the upper and side of the filament suggesting differential activation of Ca2+ permeable channels at the plasma membrane. 相似文献
977.
Ts P Dachev E G Stassinopoulous B T Tomov Pl G Dimitrov Yu N Matviichuk V A Shurshakov V M Petrov 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2003,32(1):67-71
The LIULIN-3M instrument is a further development of the LIULIN dosimeter-radiometer, used on the MIR spacestation during the 1988-1994 time period. The LIULIN-3M is designed for continuous monitoring of the radiation environment during the BION-12 satellite flight in 1999. A semiconductor detector with 1 mm thickness and cm2 area is contained in the instrument. Pulse high analysis technique is used to determine the energy losses in the detector. The final data from the instrument are the flux and the dose rate for the exposure time and 256 channels of absorbed dose spectra based on the assumption that the particle flux is normal to the detector. The LIULIN-3M instrument was calibrated by proton fluxes with different energies at the Indiana University Cyclotron Facility in June 1997 and had been used for radiation measurements during commercial aircraft flights. The calibration procedure and some flight results are presented in this paper. 相似文献
978.
J.C. Cretenet 《Acta Astronautica》1985,12(11):949-958
The presence of Europe in the future developments of spatial programs, which are foreseen, for the 1990s and further, needs the availability of vehicles, modules and all related technologies adapted to operational use of low earth orbit station.The manned HERMES vehicle shall be part of the in-orbit infrastructure realized either in the European context or in cooperation between Europe and the United States.The main mission for this vehicle will be to run a shuttle with the station that means transport and change of the crews, its safe return in abort condition and cargo transport of consumable and experimental equipment.Secondary missions could be servicing on automatic platform, making autonomous scientific experiments. Lastly, the vehicle, by means of its on-board propulsion capability, could be used to accomplish in-orbit tow and assembly missions.Studies which are undertaken now about the vehicle are devoted to the aerodynamic shape (research of a compromise between aerothermic and overall fitting), the system (functional architecture, ground and flight configuration); further works dealing with technology are presently on hand in the field of thermal protection, aerodynamics, power generation with a high massic yield. 相似文献
979.
J W Wilson R K Tripathi G D Qualls F A Cucinotta R E Prael J W Norbury J H Heinbockel J Tweed 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2004,34(6):1319-1327
Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design. 相似文献
980.
The study of the electrical environment of the Earth's atmosphere has rapidly advanced during the past century. Great strides have been made towards the understanding of lightning and thunderstorms and in relating them to the global electric circuit. The electromagnetic fields and currents connect different parts of the Earth's environment, and any type of perturbation in one region affects another region. Starting from the traditional views in which the electrodynamics of one region has been studied in isolation from the neighboring regions, the modern theory of the global electrical circuit has been discussed briefly. Interconnection and electrodynamic coupling of various regions of the Earth's environment can be easily studied by using the global electric circuit model. Deficiencies in the model and the possibility of improvement in it have been suggested. Application of the global electric circuit model to the understanding of the Earth's changes of climate has been indicated. 相似文献