Cell morphological, ontogenic, and genetic reactions to 0-g simulation and hyper-g

Organisms use gravity for spatial orientation, and differentiation into species during evolution follows geological processes which are caused by gravity. On the other hand, the task of most organismic functions which have or may have a relation to gravity is to compensate gravity. Furthermore, today it is very obvious that organisms do not disintegrate under the conditions of weightlessness, at least for the currently tested durations. These previous statements indicate a large field of still unknown regulation and adaptation mechanisms. Experiments to simulate weightlessness on the fast clinostat and with hyper-g show a highly developed ability of the genetic chain and of differentiating cells in being autonomous against mechanical stresses caused by outer accelerations. Nevertheless, different strong and slight changes of different tested end points were found. The question remains if the cells react actively or only passively.     

An investigation of small GOES flares with intense hard X-ray bursts

Most solar flare observations show that intense hard X-ray bursts come from large flares that have a large GOES classification (large peak 1 – 8 Å flux). This correlation, known as the “Big Flare Syndrome”, suggests that more intense flares tend to have harder spectra. We have observed 7 flares that are exceptions to this. These flares have small GOES classifications ranging from B1.4 to C5.5 and peak hard X-ray count rates similar to those often observed from M class flares. This paper examines the cause of this anomoly using the Yohkoh Soft X-Ray Telescope, Hard X-Ray Telescope, and Bragg Crystal Spectrometer. Two hypotheses are proposed for the exceptions: (1) flares with multiple magnetic loops and common footpoints, producing multiple hard X-ray emission regions and low density thermal plasma distributed over a large volume, and (2) high densities in the magnetic loops restricting the propagation of the non-thermal electrons in the loop after magnetic reconnection has occurred and suppressing chromospheric evaporation. Two of the flares support the first hypothesis. The other flares either have data missing or are too small to be properly analysed by the Yohkoh instruments.     

Lower and Upper Ionosphere of Mars

The ionosphere of Mars has been explored mostly with the radio occultation experiment onboard Mariners 6, 7, 9; Mars 2, 3, 4, 6; Viking 1, 2, and more recently on Mars Global Surveyor (MGS) and Mars Express (MEX). In addition to the radio occultation experiment, MEX also carried Mars Advanced Radar for the Subsurface and Ionosphere Sounding (MARSIS) experiment which provided electron density profiles well above the main ionospheric peak. The atmosphere of Mars was measured directly by the neutral mass spectrometer onboard Viking 1 and 2 Landers. Later, an accelerometer and radio occultation experiment on MGS provided large data sets of atmospheric density at various locations in the upper and lower atmospheres of Mars, respectively. In this paper we review results of these upper and lower atmospheric/ionospheric measurements. Results of these measurements have been compared with theoretical models by several workers; therefore, we also review various atmospheric and ionospheric models of Mars.     

Space radiation dosimetry with active detections for the scientific program of the second Bulgarian cosmonaut on board the Mir space station.

A dosimetry-radiometry system has been developed at the Space Research Institute of the Bulgarian Academy of Science to measure the fluxes and dose rates on the flight of the second Bulgarian cosmonaut. The dosimetry system is designed for monitoring the different space radiations, such as solar cosmic rays, galactic cosmic rays and trapped particles in the earth radiation belts. The system consists of a battery operated small size detector unit and a "read-write" and telemetry microcomputer unit. The sensitivity of the instrument (3.67 x 10(-8) rad/pulse) permits high resolution measurements of the flux and dose rate along the track of the Mir space station. We report our initial results for the period of the flight between the 7th and 17th June 1988.     

Ground based ISS payload microgravity disturbance assessments

In order to verify that the International Space Station (ISS) payload facility racks do not disturb the microgravity environment of neighboring facility racks and that the facility science operations are not compromised, a testing and analytical verification process must be followed. Currently no facility racks have taken this process from start to finish. The authors are participants in implementing this process for the NASA Glenn Research Center (GRC) Fluids and Combustion Facility (FCF). To address the testing part of the verification process, the Microgravity Emissions Laboratory (MEL) was developed at GRC. The MEL is a 6 degree of freedom inertial measurement system capable of characterizing inertial response forces (emissions) of components, sub-rack payloads, or rack-level payloads down to 10(-7) g's. The inertial force output data, generated from the steady state or transient operations of the test articles, are utilized in analytical simulations to predict the on-orbit vibratory environment at specific science or rack interface locations. Once the facility payload rack and disturbers are properly modeled an assessment can be made as to whether required microgravity levels are achieved. The modeling is utilized to develop microgravity predictions which lead to the development of microgravity sensitive ISS experiment operations once on-orbit. The on-orbit measurements will be verified by use of the NASA GRC Space Acceleration Measurement System (SAMS). The major topics to be addressed in this paper are: (1) Microgravity Requirements, (2) Microgravity Disturbers, (3) MEL Testing, (4) Disturbance Control, (5) Microgravity Control Process, and (6) On-Orbit Predictions and Verification.     

磁暴对海南地区电离层扩展F的影响

利用2002年2月至2007年12月海南地区DPS-4测高仪观测数据, 用统计分析方法研究了磁暴对电离层扩展F的影响. 结果认为磁暴从整体上抑制了扩展F现象的发生. 但若把扩展F分为不同类型, 则结果却有所不同. 对于频率型(FSF), 在2002年和2003年磁暴对其有促发作用, 在2004---2007年有抑制作用; 对于区域型(RSF), 在2002---2005年磁暴对其有抑制作用, 在2006年和2007年, 对其有弱促发作用; 对于混合型(MSF), 在2002年磁暴对其有抑制作用, 在2003年和2004年有促发作用, 从2005年开始, 磁暴对其有抑制作用; 对于强区域型 (SSF), 在2002---2004年磁暴对其有抑制作用, 在2005年和2006年有促发作用, 2007年有弱抑制作用.     

一种新型多普勒噪声抑制技术对BepiColombo任务无线电科学实验的性能提升

在欧洲空间局和日本宇宙开发机构联合开展的BepiColombo水星任务中,将开展水星轨道器无线电科学实验,包括估计水星的引力场及其旋转状态,并对广义相对论进行验证。目前地面系统和星上设备的主流配置可以在无线电科学实验中建立X/X、X/Ka和Ka/Ka多个频段的链路,测速精度可达3 um/s（1 000 s积分）,测距精度为20 cm。提出了基于时延机械噪声对消技术提高无线电科学实验性能的方案。时延机械噪声对消技术需要处理在两个测站不同时刻的测量数据,一个测站实施双向多普勒测距,对另一个单收测站的要求较为严格,该测站需要具有较好的对流层条件。这种方法能够显著降低Ka频段双向链路的主要测量噪声,包括由对流层和天线机械系统震动引起的噪声。我们给出了端到端的仿真性能,并估计了在使用时延机械噪声对消技术前提下的水星引力场和旋转状态。考虑使用NASA位于美国本土戈尔德斯敦的DSS-25天线或欧空局位于阿根廷马拉圭的DSA-3天线作为双程测量站,并考虑使用位于智力的APEX天文观测天线作为单收站。分析结果表明在最好的噪声条件下,使用DSA-3天线作为双程测量站时,时延机械噪声对消技术可将待估计的全局和局部参数的估计精度提升一倍。对于无线电科学实验的目标,这一可能的性能提升对行星地质物理学很有意义,它将有益于研究水星内部的结构。     

Augmenting the Linear Variance Equation

A technique is developed to convert the covariance analysis ofcertain time-varying linear systems into time-invariant form, thusallowing an arbitrary time step for the solution of the differentialequations. The result is accomplished by augmenting the linearvariance equation and augmenting the state vector if necessary. Themethod is illustrated with an example showing the covariancepropagation of ring laser gyro errors in a strapdown inertial systeminto navigation errors during turns.     

Effects of microgravity on c-fos gene expression in osteoblast-like MC3T3-E1 cells.

The paper summarizes the data on proliferation and gravity-related gene expression of osteoblasts that were obtained from an experiment conducted under simulated and real microgravity conditions. Simulated microgravity conditions obtained in a clinostat depress proliferation of both osteoblast-like MC3T3-E1 and HeLa carcinoma cells. This depression of proliferation occurs in a collagen gel culture in which the flow of culture medium by rotation may be reduced. Interestingly, MC3T3-E1 cells which are probably one of target cells to microgravity are more sensitive than the HeLa cells. Simulated microgravity inhibited the epidermal growth factor (EGF)-induced c-fos gene expression in the MC3T3-El cells. To examine in detail the effect of real microgravity on the EGF signal transduction cascade in osteoblasts, MC3T3-E1 cells were cultured in the Cell Culture Experiment Module of the sounding rocket TR-1A6. The EGF-induced c-fos expression in cells was depressed under short-term microgravity conditions in the sounding rocket, while the phosphorylation of mitogen-activated protein kinase (MAPK) was not affected compared with the controls grown on the ground. These results suggest that an action site of microgravity in the signal transduction pathway may be downstream of MAPK.