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181.
We investigated the spatial distribution of the induction of the phosphorylated form of the histone protein H2AX (gamma-H2AX), known to be activated by DSBs. Following irradiation of human fibroblast cells with 600 MeV/nucleon silicon and 600 MeV/nucleon iron ions we observed the formation of gamma-H2AX aggregates in the shape of streaks stretching over several micrometers in an x/y plane. Polyethylene shielding was used to achieve a Bragg curve distribution with beam geometry parallel to the monolayer of cells. We present data that highlights the formation of immunofluorescent gamma-H2AX tracks showing the ion trajectories across the Bragg peak of irradiated human fibroblast cells. Qualitative analyses of these distributions indicated potentially increased clustering of DNA damage before the Bragg peak, enhanced gamma-H2AX distribution at the peak, and provided visual evidence of high-linear energy transfer particle traversal of cells beyond the Bragg peak in agreement with one-dimensional transport approximations. Spatial assessment of gamma-H2AX fluorescence may provide direct insights into DNA damage across the Bragg curve for high charge and energy ions including the biological consequences of shielding and possible contributors to bystander effects.  相似文献   
182.
The combination of Voyager 1 (77.9 AU, 34.4° N) and Voyager 2 (61.2 AU, 24.5° S) at moderate heliolatitudes in the distant heliosphere and Ulysses with its unique latitudinal surveys in the inner heliosphere along with IMP 8 and other satellites at 1 AU constitutes a network of observatories that are ideally suited to study cosmic rays over the solar minimum of cycle 22 and the onset of solar activity and the long term cosmic ray modulation of cycle 23. Through 2000.7 there have been three well-defined step decreases in the cosmic ray intensity at 1 AU with the cumulative effect being in good agreement with the net decrease in cycle 21 at a comparable time in the solar cycle. Over this period the intensity changes at Ulysses are similar to those at 1 AU. In the distant heliosphere the initial decreases appear to be smaller than those at 1 AU. However the full effects of the interplanetary disturbances producing the most recent and largest step decrease in the inner heliosphere have not yet reached V-2. This revised version was published online in August 2006 with corrections to the Cover Date.  相似文献   
183.
The basic thermodynamical equations for values which characterize the surface (as curvatures, thickness, surface density of extensive value and its fluxes) are derived with real thickness of the surface being taken into consideration. The terms in the equations connect the thickness with the curvature as well as with the fluxes, surface densities and production of extensive properties. The extended thermodynamical fluxes contain terms in which the thickness and curvature of surface are explicitly expressed.  相似文献   
184.
This paper deals with the principal methods of achieving high-time resolution measurements for the study of fine structure of shocks and other discontinuities in space plasmas. In the measurements of ion energy spectra, we have obtained the time resolution about 1s.In the Soviet-Czechoslovak INTERSHOCK project we will obtain temporal resolution better than 0.1s in the measurement of the main plasma parameters. This will be obtained with the multichannel energy spectrometer and the on-board data acquisition and processing system triggered by the shock signature. This system controls the data sampling rate from some scientific instruments and switches on a high-sampling rate near the shock. The method implies detecting a shock by means of on-board processing of magnetic field and plasma parameters. The algorithm for this detection uses both parameters separately as well as in combinations.  相似文献   
185.
The detection and repair of the cycle slip or gross error is a key step for high precision global positioning system (GPS) carrier phase navigation and positioning due to interruption or unlocking of GPS signal. A number of methods have been developed to detect and repair cycle slips in the last two decades through cycle slip linear combinations of available GPS observations, but such approaches are subject to the changing GPS sampling and complex algorithms. Furthermore, the small cycle slip and gross error cannot be completely repaired or detected if the sampling is quite longer under some special observation conditions, such as Real Time Kinematic (RTK) positioning. With the development of the GPS modernization or Galileo system with three frequencies signals, it may be able to better detect and repair the cycle slip and gross error in the future. In this paper, the cycle slip and gross error of GPS carrier phase data are detected and repaired by using a new combination of the simulated multi-frequency GPS carrier phase data in different conditions. Results show that various real-time cycle slips are completely repaired with a gross error of up to 0.2 cycles.  相似文献   
186.
Considering the KuaFu mission, state of the energy release of substorm and storm is simply presented and it’s improvements by KuaFu mission are investigated. The KuaFu mission will provide us an opportunity to improve our understanding of the energy release during the storm and the substorms. The two KuaFu-B satellites flying in 180° phase-lagged formation in a polar orbit will allow synoptic observations of the auroral oval, central plasma sheet, ring current and other regions. It can monitor the polar region 24/7 continuously. The advantage of the KuaFu mission is to provide the data during all phases of storm and substorm time that can be used to study the global energy release during all phases continuously. The data from auroral imager and other in-situ instruments on board KuaFu-B can be used to study the auroral dynamics and Joule heating during a storm and substorm. The data from the neutral atom imager instrument can be used to study the dynamics and the energy release in the ring current region from sudden commencement to complete storm recovery. Furthermore the data from KuaFu-A, which is around L1 point, can be used to study the interplanetary conditions along with the data from the plasma sheet to study the triggering process and energy release during a substorm. So, KuaFu mission with its continuous time monitoring facilities would enable us to make much progress towards solving the underlying problems.  相似文献   
187.
Trajectories of spacecraft with electro-jet low-thrust engines are studied for missions planning to deliver samples of matter from small bodies of the Solar System: asteroids Vesta and Fortuna, and Martian moon Phobos. Flight trajectories are analyzed for the mission to Phobos, the limits of optimization of payload spacecraft mass delivered to it are determined, and an estimate is given to losses in the payload mass when a low-thrust engine with constant outflow velocity is used. The model of an engine with ideally regulated low thrust is demonstrated to be convenient for calculations and analysis of flight trajectories of a low-thrust spacecraft.  相似文献   
188.
189.
萤火一号卫星将对火星空间环境磁场实施探测. 火星磁场对火星弓激波、磁鞘、电离层、大气等绝大多数空间环境效应都具有重要影响, 萤火一号对火星磁场的探测是通过搭载于其上的科学载荷磁强计来实现的. 此磁强计在工作原理及具体设计上, 考虑了火星轨道严酷的工作环境和科学目标所需的测量要求. 通过装星前的地面标定测试, 验证了萤火一号磁强计可以在-130~75°C温度范围内测量±256 nT以内的磁场, 分辨率可达到0.01 nT, 带宽内总噪声小于0.03 nT, 能够满足萤火一号对火星空间环境探测的需求.  相似文献   
190.
This chapter provides an overview of current efforts in the theory and modeling of CMEs. Five key areas are discussed: (1) CME initiation; (2) CME evolution and propagation; (3) the structure of interplanetary CMEs derived from flux rope modeling; (4) CME shock formation in the inner corona; and (5) particle acceleration and transport at CME driven shocks. In the section on CME initiation three contemporary models are highlighted. Two of these focus on how energy stored in the coronal magnetic field can be released violently to drive CMEs. The third model assumes that CMEs can be directly driven by currents from below the photosphere. CMEs evolve considerably as they expand from the magnetically dominated lower corona into the advectively dominated solar wind. The section on evolution and propagation presents two approaches to the problem. One is primarily analytical and focuses on the key physical processes involved. The other is primarily numerical and illustrates the complexity of possible interactions between the CME and the ambient medium. The section on flux rope fitting reviews the accuracy and reliability of various methods. The section on shock formation considers the effect of the rapid decrease in the magnetic field and plasma density with height. Finally, in the section on particle acceleration and transport, some recent developments in the theory of diffusive particle acceleration at CME shocks are discussed. These include efforts to combine self-consistently the process of particle acceleration in the vicinity of the shock with the subsequent escape and transport of particles to distant regions.  相似文献   
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