Properties of electrophoretic fractions of human embryonic kidney cells separated on Space Shuttle flight STS-8.

Suspensions of cultured primary human embryonic kidney cells were subjected to continuous flow electrophoresis on Space Shuttle flight STS-8. The objectives of the experiments were to obtain electrophoretically separated fractions of the original cell populations and to test these fractions for the amount and kind of urokinase (a kidney plasminogen activator that is used medically for digesting blood clots), the morphologies of cells in the individual fractions, and their cellular electrophoretic mobilities after separation and subsequent proliferation. Individual fractions were successfully cultured after return from orbit, and they were found to differ substantially from one another and from the starting sample with respect to all of these properties.     

Optimal Design Strategy of Switching Converters Employing Current in jected Control

This paper analyzes a buck/boost regulator employing current-injected control (CIC). It reveals the complex interactions between the dc loop and the current-injected loop and underlines the fundamental principle that governs the loop gain determination. Three commonly used compensation techniques are compared. The integral and lead/lag compensation are shown to be most desirable for performance optimization and stability.     

Comet Halley: Nucleus and jets (results of the VEGA mission)

The VEGA-1 and VEGA-2 spacecraft made their closest approach to Comet Halley on 6 and 9 March, respectively. In this paper those results of the onboard imaging experiment which were obtained around closest approach are discussed. The nucleus of the comet was clearly identifiable as an irregularly shaped object, with overall dimensions of (16±1)×(8±1)×(8±1) km. The nucleus rotates in the prograde sense about an axis nearly perpendicular to the orbital plane with a period of 53±2 hours. Its albedo is only $\text{0.04±}\text{0.02}\text{0.01}$ Many of the jet features observed during the second fly-by have been spatially reconstructed. Their sources form a quasi-linear structure on the surface. The dust above the surface is shown to be generally optically thin with the exception of certain specific dust jets. Brightness features on the surface are clearly seen. Correlating our data with other measurements, we conclude that the dirty snow-ball model will probably need to be revised.     

Modeling international cooperation in human space exploration for the twenty-first century.

The policy process of international cooperation in space exploration. including optimistic and pessimistic scenarios for the twenty-first century, is modeled and examined in this study. In the optimistic scenario, international cooperation involves a balanced and interdependent distribution of capabilities between states, their respective national space agencies and communities of space scientists and space engineers. Cooperation is characterized by interstate participation in critical path components and joint research and development. In the pessimistic scenario, international cooperation is structured and dominated politically and economically by powerful states vis-a-vis weaker states. Cooperation is limited to coordination of separate nationally approved projects and augmentation of capabilities in noncritical path components. On the basis of these two scenarios, policy predictions and implications relevant to exploration missions in the twenty-first century, such as a human-tended lunar base and human missions to Mars, are presented and discussed.     

Simulation of launch and re-entry acceleration profiles for testing of shuttle and unmanned microgravity research payloads

Microgravity experiments designed for execution in Get-Away Special canisters, Hitchhiker modules, and Reusable Re-entry Satellites will be subjected to launch and re-entry accelerations. Crew-dependent provisions for preventing acceleration damage to equipment or products will not be available for these payloads during flight; therefore, the effects of launch and re-entry accelerations on all aspects of such payloads must be evaluated prior to flight. A procedure was developed for conveniently simulating the launch and re-entry acceleration profiles of the Space Shuttle (3.3 and 1.7 × g maximum, respectively) and of two versions of NASA's proposed materials research Re-usable Re-entry Satellite (8 × g maximum in one case and 4 × g in the other). By using the 7 m centrifuge of the Gravitational Plant Physiology Laboratory in Philadelphia it was found possible to simulate the time dependence of these 5 different acceleration episodes for payload masses up to 59 kg. A commercial low-cost payload device, the “Materials Dispersion Apparatus” of Instrumentation Technology Associates was tested for (1) integrity of mechanical function, (2) retention of fluid in its compartments, and (3) integrity of products under simulated re-entry g-loads. In particular, the sharp rise from 1 g to maximum g-loading that occurs during re-entry in various unmanned vehicles was successfully simulated, conditions were established for reliable functioning of the MDA, and crystals of 5 proteins suspended in compartments filled with mother liquor were subjected to this acceleration load.     

BAS—The project of an earth-atmosphere spectrophotometer for basic research

The earth-atmosphere spectrophotometer BAS is intended to be used for basic research in the field of remote sensing. The main advantages of BAS are the possibility of a high-accuracy calibration in absolute units utilizing the extraterrestrial spectral solar energy distribution and its simultaneous use for radiance and for irradiance measurements, e.g. the same spectrophotometer BAS to measure immediately one after the other the high irradiances of the sun (transmission measurement) and very low radiances of water surfaces.Data evaluation will be made immediately by the BAS-linked computer for field measurements.Further important technical parameters of BAS are the scanning of the spectral range 0.38 to 1.12 μm in 40 steps within 3 s, low mass of about 4 kg, power supply by rechargeable battery pack. BAS is also suited for measurements to be made from airborne and shipborne platforms.Different applications are shown by some examples.     

Vehicular Positioning System

There is a US Army vehicular positioning program under way called MAFIS (Mobile Automated Field Instrumentation System). Though its use is intended for full scale battlefield operational testing of mobile ground units and aircraft systems, the implications for extending this technology toward commercial aplications are the thrust of this paper.     

GENERATION AND APPLICATION OF UNSTRUCTURED ADAPTIVE MESHES WITH MOVING BOUNDARIES

INTRODUCTIONMany engineering applications require thenumerical prediction of strongly unsteady flowsinteracting with moving bodies.A case in pointis that the detailed calculation of sphere motionsin an unsteady field induced by blast waves is akey issue to determine the drag force exerting up-on the sphere by the surrounding gas and,inturn,to reveal the mechanism of unsteady effectson the drag coefficient.To cope with such pro-blems,one should simulate unsteady flows withmoving boundary co…     

Meteors do not break exogenous organic molecules into high yields of diatomics

Meteoroids that dominate the Earth's extraterrestrial mass influx (50-300 microm size range) may have contributed a unique blend of exogenous organic molecules at the time of the origin of life. Such meteoroids are so large that most of their mass is ablated in the Earth's atmosphere. In the process, organic molecules are decomposed and chemically altered to molecules differently from those delivered to the Earth's surface by smaller (<50 microm) micrometeorites and larger (>10 cm) meteorites. The question addressed here is whether the organic matter in these meteoroids is fully decomposed into atoms or diatomic compounds during ablation. If not, then the ablation products made available for prebiotic organic chemistry, and perhaps early biology, might have retained some memory of their astrophysical nature. To test this hypothesis we searched for CN emission in meteor spectra in an airborne experiment during the 2001 Leonid meteor storm. We found that the meteor's light-emitting air plasma, which included products of meteor ablation, contained less than 1 CN molecule for every 30 meteoric iron atoms. This contrasts sharply with the nitrogen/iron ratio of 1:1.2 in the solid matter of comet 1P/Halley. Unless the nitrogen content or the abundance of complex organic matter in the Leonid parent body, comet 55P/Tempel-Tuttle, differs from that in comet 1P/Halley, it appears that very little of that organic nitrogen decomposes into CN molecules during meteor ablation in the rarefied flow conditions that characterize the atmospheric entry of meteoroids approximately 50 microm-10 cm in size. We propose that the organics of such meteoroids survive instead as larger compounds.