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951.
Results of a numerical (CFD) study of the influence of the forebody shape on local flow parameters at a bottom-mounted inlet entrance are presented. The free-stream Mach number is assumed to be 3.5–7.0. Some recommendations on forebody shape optimization are provided. Main characteristics of the air inlet are evaluated.  相似文献   
952.
Residual chromatin breaks as biodosimetry for cell killing by carbon ions   总被引:5,自引:0,他引:5  
We have studied the relationship between cell killing and the induction of residual chromatin breaks on various human cell lines and primary cultured cells obtained by biopsy from patients irradiated with either X-rays or heavy-ion beams to identify potential bio-marker of radiosensitivity for radiation-induced cell killing. The carbon-ion beams were accelerated with the Heavy Ion Medical Accelerator in Chiba (HIMAC). Six primary cultures obtained by biopsy from 6 patients with carcinoma of the cervix were irradiated with two different mono-LET beams (LET= 13 keV/μm, 76 keV/μm) and 200kV X rays. Residual chromatin breaks were measured by counting the number of non-rejoining chromatin fragments detected by the premature chromosome condensation (PCC) technique after a 24 hour postirradiation incubation period. The induction rate of residual chromatin breaks per cell per Gy was the highest for 76 keV/μm beams on all of the cells. Our results indicated that cell which was more sensitive to the cell killing was similarly more susceptible to induction of residual chromatin breaks. Furthermore there is a good correlation between these two end points in various cell lines and primary cultured cells. This suggests that the detection of residual chromatin breaks by the PCC technique may be useful as a predictive assay of tumor response to cancer radiotherapy.  相似文献   
953.
Neurobiological problems in long-term deep space flights.   总被引:1,自引:0,他引:1  
Future missions in space may involve long-term travel beyond the magnetic field of the Earth, subjecting astronauts to radiation hazards posed by solar flares and galactic cosmic rays, altered gravitation fields and physiological stress. Thus, it is critical to determine if there will be any reversible or irreversible, detrimental neurological effects from this prolonged exposure to space. A question of particular importance focuses on the long-term effects of the space environment on the central nervous system (CNS) neuroplasticity, with the potential acute and/or delayed effects that such perturbations might entail. Although the short-term effects of microgravity on neural control were studied on previous low earth orbit missions, the late consequences of stress in space, microgravity and space radiation have not been addressed sufficiently at the molecular, cellular and tissue levels. The possibility that space flight factors can interact influencing the neuroplastic response in the CNS looms critical issue not only to understand the ontogeny of the CNS and its functional integrity, but also, ultimately the performance of astronauts in extended space forays. The purpose of this paper is to review the neurobiological modifications that occur in the CNS exposed to the space environment, and its potential consequences for extended deep space flight.  相似文献   
954.
In the 18.5-day flight of the Soviet biosatellite Cosmos-936 (3-22, August 1977) com-parative investigations of the physiological effects of prolonged weightlessness (20 rats) and artificial gravity of 1 g (10 rats) were carried out. Throughout the flight artificial gravity was generated by means of animal rotation in two centrifuges with a radius of 320mm. Postflight examination of animals and treatment of the flight data were performed by Soviet scientists in collaboration with the specialists from Bulgaria, Czechoslovakia, the German Democratic Republic, Hungary, Poland, Rumania, France and the U.S.A. During the flight the total motor activity of the weightless rats was higher and their body temperature was lower than those of the centrifuged animals. Postflight examination of the weightless rats showed a greater percentage of errors during maze an increase in water intake and a decrease in diuresis; a fall of the resistance of peripheral red cells; an increase in the conditionally pathogenic microflora in the mouth; a decrease of oxygen consumption, carbon dioxide production and energy expenditures; a drop in the static physical endurance; a decline in the capacity to keep balance on the rail; an increase in the latent period of the lifting reflex, etc. The centrifugal animals displayed lesser or no change of the above type. These findings together with the biochemical and morphological data give evidence that during and after flight adaptive processes in the centrifuged rats developed better.  相似文献   
955.
The perturbation problem that describes the effect of a weak magnetic field on stellar adiabatic oscillation is considered. This perturbation problem is singular when the magnetic field does not vanish at the stellar surface, and a regular perturbation scheme fails where the magnetic pressure is comparable to the thermodynamic pressure. The application of the Method of Matched Asymptotic Expansion is used to obtain expressions for the eigenfunctions and the eigenfrequencies.  相似文献   
956.
Previous work on the latitudinal gradient and on the amplitude of the recurrent cosmic ray decreases, has shown that their magnitude does not decrease monotonically with the particle rigidity, but it presents a broad maximun around 1–2 GV. We have extended this analysis to study the behaviour of cosmic-ray particles during the modulation steps in the rising part of the solar activity of the present Solar cycle. We found that the ‘depth’ of the modulation step decreases monotonically with increasing rigidity and that the least energetic particles are the last to reach their minimum intensity value. We also considered in this analysis electrons of equal rigidity to study the influence of the charge sign on the particle behaviour during the modulation steps. This revised version was published online in August 2006 with corrections to the Cover Date.  相似文献   
957.
The problem of fracture mechanics for the solid propellant deteriorated by a crack-shaped cavity, the surface of which burns is considered. It is assumed that the propellant reagents are uniformly distributed in the solid phase while the combustion products are gaseous. The sufficient condition for the “combustion -fracture” stability regime is obtained.  相似文献   
958.
The general differential equations for the circuits of a homopolar inductor alternator are established. The system of equations is modified for the case of nonsymmetrical subtransient operation. The Runge-Kutta and Adams-Moulton methods are used to solve the system of differential equations with variable coefficients. The solution is obtained for different initial conditions. Several damper winding designs are analyzed. A step-by-step correction method in the time domain is used to improve the approximate initial value of the subtransient reactance. This method takes care of saturation, which changes greatly during a subtransient. The analysis of the most advantageous design of the axial damper winding located in the armature slots is given in this paper. All calculations were carried out for the same alternator as used in the companion paper [1].  相似文献   
959.
An extension is presented to the particle filtering toolbox that enables nonlinear/non-Gaussian filtering to be performed in the presence of out-of-sequence measurements (OOSMs) with arbitrary lag, without the need to adopt linearising approximations in the filter and without the degradation of performance that would occur if the OOSMs were simply discarded. An estimate of the performance of the OOSM particle filter (OOSM-PF) is obtained for bearings-only tracking scenarios with a single target and a small number of sensors. These performance estimates are then compared with the posterior Cramer-Rao lower bound (CRLB) for the state estimate rms error and similar performance estimates obtained from the oosm extended Kalman filter (OOSM-EKF) algorithms recently introduced in the literature. For a mildly nonlinear bearings-only tracking problem the OOSM-PF and OOSM-EKF are shown to achieve broadly similar performance.  相似文献   
960.
The Lightning and Radio Emission Detector (LRD) instrument will be carried by the Galileo Probe into Jupiter's atmosphere. The LRD will verify the existence of lightning in the atmosphere and will determine the details of many of its basic characteristics. The instrument, operated in its magnetospheric mode at distances of about 5, 4, 3, and 2 planetary radii from Jupiter's center, will also measure the radio frequency (RF) noise spectrum in Jupiter's magnetosphere. The LRD instrument is composed of a ferritecore radio frequency antenna ( 100 Hz to 100 kHz) and two photodiodes mounted behind individual fisheye lenses. The output of the RF antenna is analyzed both separately and in coincidence with the optical signals from the photodiodes. The RF antenna provides data both in the frequency domain (with three narrow-band channels, primarily for deducing the physical properties of distant lightning) and in the time domain with a priority scheme (primarily for determining from individual RF waveforms the physical properties of closeby-lightning).  相似文献   
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