The role of hydration and radiation quality in the induction of DNA damage--chemical aspects.

The mutagenic and lethal effects of ionising radiation are thought to result from chemical modifications induced within DNA. This DNA damage is significantly influenced by the chemical environment and the radiation quality (LET). Water closely associated with the DNA and its immediate environment is involved in the early chemical pathways which lead to the induction of DNA damage and is reflected in the cellular radiosensitivity. For instance, hydration of DNA influences hole migration leading to its localisation at guanine. Changes in the radiation quality are discussed in terms of the complexity of the radical clusters produced. It is inferred that at higher LET, the influence of the chemical environment (O2 etc) decreases with respect to DNA damage and cellular radiosensitivity. It is therefore important to include these effects of environment of the DNA upon the early chemical pathways in models of radiation action.     

Analysis of radiation risk from alpha particle component of solar particle events.

The solar particle events (SPE) will contain a primary alpha particle component, representing a possible increase in the potential risk to astronauts during an SPE over the often studied proton component. We discuss the physical interactions of alpha particles important in describing the transport of these particles through spacecraft and body shielding. Models of light ion reactions are presented and their effects on energy and linear energy transfer (LET) spectra in shielding discussed. We present predictions of particle spectra, dose, and dose equivalent in organs of interest for SPE spectra typical of those occurring in recent solar cycles. The large events of solar cycle 19 are found to have substantial increase in biological risk from alpha particles, including a large increase in secondary neutron production from alpha particle breakup.     

Distributed flight control system using fiber distributed datainterface (FDDI)

The design of fault-tolerant distributed control systems is discussed. The application described is a generic flight control system (FCS) for a fighter aircraft. The system is designed for high redundancy and expandability to meet various requirements. The communication network is based on the fiber distributed data interface (FDDI), which provides a high level of electromagnetic interference resistance and reliability. The choice of fiber optic media also provides an extremely high bandwidth and tremendous growth capability for future communications needs. This study is not specific to FDDI or flight control systems. The methods and configurations presented should be applicable to many real-time control implementations     

Critical issues in connection with human missions to Mars: protection of and from the Martian environment.

Human missions to Mars are planned to happen within this century. Activities associated therewith will interact with the environment of Mars in two reciprocal ways: (i) the mission needs to be protected from the natural environmental elements that can be harmful to human health, the equipment or to their operations; (ii) the specific natural environment of Mars should be protected so that it retains its value for scientific and other purposes. The following environmental elements need to be considered in order to protect humans and the equipment on the planetary surface: (i) cosmic ionizing radiation, (ii) solar particle events; (iii) solar ultraviolet radiation; (iv) reduced gravity; (v) thin atmosphere; (vi) extremes in temperatures and their fluctuations; and (vii) surface dust. In order to protect the planetary environment, the requirements for planetary protection as adopted by COSPAR for lander missions need to be revised in view of human presence on the planet. Landers carrying equipment for exobiological investigations require special consideration to reduce contamination by terrestrial microorganisms and organic matter to the greatest feasible extent. Records of human activities on the planet's surface should be maintained in sufficient detail that future scientific experimenters can determine whether environmental modifications have resulted from explorations.     

Features of active sidestick controllers

This paper discusses the advantages of incorporating active sidesticks into a modern aircraft cockpit. Active sidestick controllers for manual pilot inputs in pitch and roll are examined for commercial transport aircraft. Options and requirements for sidesticks are reviewed. The recommendation of an active sidestick controller is developed providing both cross-cockpit coupling and autopilot backdrive capability. These characteristics provide pilot cues identical to traditional cable-linked column/yoke configurations     

Methodologies in user interface design

Software applications that require a high learning curve, a mountain of documentation, and weeks of training should be things of the past. Today's applications need to be simple to learn and to use. The human/computer interface should be intuitive and consistent. Context sensitive help should be available to keep the user on track. This paper provides some guidelines for taking commercial world concepts and applying them to the Automatic Test Equipment world. Examples included are from the Integrated Maintenance Information System (IMIS)     

Multiwavelength monitoring of active galactic nuclei

Recent multiwavelength monitoring of active galactic nuclei (AGN), particularly with the IUE satellite, has produced extraordinary advances in our understanding of the energy-generation mechanism(s) in the central engine and of the structure of the surrounding material. Examples discussed here include both ordinary AGN and blazars (the collective name for highly variable, radio-loud AGN like BL Lac objects and Optically Violently Variable quasars). In the last decade, efforts to obtain single-epoch multiwavelength spectra led to fundamentally new models for the structure of AGN, involving accretion disks for AGN and relativistic jets for blazars. Recent extensions of multiwavelength spectroscopy into the temporal domain have shown that while these general pictures may be correct, the details were probably wrong. Campaigns to monitor Seyfert 1 galaxies like NGC 4151, NGC 5548 and Fairall 9 at infrared, optical, ultraviolet and X-ray wavelengths indicate that broad-emission line regions are stratified by ionization, density, and velocity; argue against a standard thin accretion disk model; and suggest that X-rays represent primary rather than reprocessed radiation. For blazars, years of radio monitoring indicated emission from an inhomogeneous synchrotron-emitting plasma, which could also produce at least some of the shorter-wavelength emission. The recent month-long campaign to observe the BL Lac object PKS 2155-304 has revealed remarkably rapid variability that extends from the infrared through the X-ray with similar amplitude and little or no discernible lag. This lends strong support to relativistic jet models and rules out the proposed accretion disk model for the ultraviolet-X-ray continuum.     

Millimeter wave radar with clutter measurements

A portable millimeter wave test radar system, also suitable for battery operation, gives interesting possibilities for clutter recordings at hard-to-reach sites. The designed system covers all common radar frequencies from the Ka- to V-bands and enables spatial detection of targets or clutter elements within an adjustable time gate, whereby spatial clutter profiles of rain can be analyzed. The construction allows full operation with non-scanning antennas as well. This is advantageous when measuring temporal RCS variations of selected targets or surface clutter from snow dunes.     

MIT Lincoln Laboratory Journal: fifty years of radar

This review assumes that many non-US readers may not be well-informed about the steps and work in radar development in the US after WW II to the present. Many know MIT by name and recall the famous Radiation Laboratory Series. But the more recent technical history has been less in the "public domain." In an attempt to correct this, one of the key institutions in the field, the MIT Lincoln Laboratory two years ago produced a special issue of their regular publication. Although the document currently at hand is not a book in the strict sense, the size, shape, and editorial comprehensiveness of the MIT Lincoln Laboratory Journal's Fifty-Year Anniversary Issue (12, 2, 2000) justifies calling this article being treated as a book review.     

Space experiment on behaviors of treefrog.

Japanese treefrogs (Hyla japonica) are planned to be sent to the space station MIR. Experimental system was developed to observe their behaviors under microgravity.