Evaluation of upper body muscle activity during cardiopulmonary resuscitation performance in simulated microgravity

Performance of efficient single-person cardiopulmonary resuscitation (CPR) is vital to maintain cardiac and cerebral perfusion during the 2–4 min it takes for deployment of advanced life support during a space mission. The aim of the present study was to investigate potential differences in upper body muscle activity during CPR performance at terrestrial gravity (+1Gz) and in simulated microgravity (μG). Muscle activity of the triceps brachii, erector spinae, rectus abdominis and pectoralis major was measured via superficial electromyography in 20 healthy male volunteers. Four sets of 30 external chest compressions (ECCs) were performed on a mannequin. Microgravity was simulated using a body suspension device and harness; the Evetts–Russomano (ER) method was adopted for CPR performance in simulated microgravity. Heart rate and perceived exertion via Borg scores were also measured. While a significantly lower depth of ECCs was observed in simulated microgravity, compared with +1Gz, it was still within the target range of 40–50 mm. There was a 7.7% decrease of the mean (±SEM) ECC depth from 48 ± 0.3 mm at +1Gz, to 44.3 ± 0.5 mm during microgravity simulation (p < 0.001). No significant difference in number or rate of compressions was found between the two conditions. Heart rate displayed a significantly larger increase during CPR in simulated microgravity than at +1Gz, the former presenting a mean (±SEM) of 23.6 ± 2.91 bpm and the latter, 76.6 ± 3.8 bpm (p < 0.001). Borg scores were 70% higher post-microgravity compressions (17 ± 1) than post +1Gz compressions (10 ± 1) (p < 0.001). Intermuscular comparisons showed the triceps brachii to have significantly lower muscle activity than each of the other three tested muscles, in both +1Gz and microgravity. As shown by greater Borg scores and heart rate increases, CPR performance in simulated microgravity is more fatiguing than at +1Gz. Nevertheless, no significant difference in muscle activity between conditions was found, a result that is favourable for astronauts, given the inevitable muscular and cardiovascular deconditioning that occurs during space travel.     

Fuel consumption and collision avoidance strategy in multi-static orbit formations

This paper analyses the fuel consumption of interferometric radar missions employing small satellite formations like, e.g., Cross-track Pendulum, Cartwheel, CarPe, or Trinodal Pendulum. Individual analytic expressions are provided for each of the following contributions: separation from a simultaneously injected master satellite, formation set-up, orbit maintenance, formation maintenance, and distance maintenance. For this, a general system of equations is derived describing the relative motion of the small satellites in a co-rotating reference frame. The transformation into Keplerian elements is carried out. To evaluate fuel consumption, three master satellites are assumed in different orbital heights, which are typical for Earth observation missions. The size of the exemplarily analysed formations is defined by remote sensing aspects and their respective fuel requirements are estimated. Furthermore, a collision avoidance concept is introduced, which includes a formation separation and formation set-up after a desired time period.     

The X/X/KA-band deep space transponder for the BepiColombo mission to mercury

This paper reports the main characteristics of the deep space transponder (DST) equipment that has been designed, developed and tested by Thales Alenia Space—Italy (TAS-I) for the European Space Agency (ESA) BepiColombo mission to Mercury.     

Thyrotropin receptor and membrane interactions in FRTL-5 thyroid cell strain in microgravity

The aim of this work was to analyze the possible alteration of thyrotropin (TSH) receptors in microgravity, which could explain the absence of thyroid cell proliferation in the space environment. Several forms of the TSH receptor are localized on the plasma membrane associated with caveolae and lipid rafts. The TSH regulates the fluidity of the cell membrane and the presence of its receptors in microdomains that are rich in sphingomyelin and cholesterol. TSH also stimulates cyclic adenosine monophosphate (cAMP) accumulation and cell proliferation. Reported here are the results of an experiment in which the FRTL-5 thyroid cell line was exposed to microgravity during the Texus-44 mission (launched February 7, 2008, from Kiruna, Sweden). When the parabolic flight brought the sounding rocket to an altitude of 264?km, the culture media were injected with or without TSH in the different samples, and weightlessness prevailed on board for 6 minutes and 19 seconds. Control experiments were performed, in parallel, in an onboard 1g centrifuge and on the ground in Kiruna laboratory. Cell morphology and function were analyzed. Results show that in microgravity conditions the cells do not respond to TSH treatment and present an irregular shape with condensed chromatin, a modification of the cell membrane with shedding of the TSH receptor in the culture medium, and an increase of sphingomyelin-synthase and Bax proteins. It is possible that real microgravity induces a rearrangement of specific sections of the cell membrane, which act as platforms for molecular receptors, thus influencing thyroid cell function in astronauts during space missions.     

Compact frequency standard using atoms trapped on a chip

We present a compact atomic frequency standard based on the interrogation of magnetically trapped ⁸⁷Rb atoms. Two photons, in the microwave and radiofrequency domain excite the atomic transition. At a magnetic field of 3.23 G this transition from ∣F = 1, m_F = −1〉 to ∣F = 2, m_F = 1〉 is 1st order insensitive to magnetic field variations. Long Ramsey interrogation times can thus be achieved, leading to a projected stability in the low 10⁻¹³ at 1 s. This makes this device a viable alternative to LITE and HORACE as a good candidate for replacing or complementing the rubidium frequency standards and passive hydrogen masers already on board of the GPS, GLONASS, and GALILEO satellites. Here we present preliminary results. We use an atom chip to cool and trap the atoms. A coplanar waveguide is integrated to the chip to carry the Ramsey interrogation signal, making the physics package potentially as small as (5 cm)³. We describe the experimental apparatus and show preliminary Ramsey fringes of 1.25 Hz linewidth. We also show a preliminary frequency stability σ_y = 1.5 × 10⁻¹²τ^−1/2 for 10 < τ < 10³ s. This represents one order of magnitude improvement with respect to previous experiments.     

Drag force on solar sails due to absorption of solar radiation

We consider a special relativistic effect, known as the Poynting–Robertson effect, on various types of trajectories of solar sails. Since this effect occurs at order v^?/c, where v^? is the transversal speed relative to the sun, it can dominate over other special relativistic effects, which occur at order v²/c². While solar radiation can be used to propel the solar sail, the absorbed portion of it also gives rise to a drag force in the transversal direction. For escape trajectories, this diminishes the cruising velocity, which can have a cumulative effect on the heliocentric distance. For a solar sail directly facing the sun in a bound orbit, the Poynting–Robertson effect decreases its orbital speed, thereby causing it to slowly spiral towards the sun. We also consider this effect for non-Keplerian orbits in which the solar sail is tilted in the azimuthal direction. While in principle the drag force could be counter-balanced by an extremely small tilt of the solar sail in the polar direction, periodic adjustments are more feasible.     

Does the endolymph pass through the base of the cupula?

Whether the endolymph of the semicircular canal passes the cupular partition or not was examined using the lateral semicircular canal system of adult pigeons (Columba livia). By applying various pressures by means of injection of a dye solution through the membranous canal, it was found that the dye solution, was seen to pass the cupula even under very low pressures when the pressure was increased gradually. When pulled by a magnet, the ultrafine particles of the dextran magnetite contained in the injected fluid were found to pass through the subcupular space without evident increase of the ampullary pressure.