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The aim of this study was to investigate the influence of an exercise device, designed to improve the function of lumbopelvic muscles via low-impact weight-bearing exercise, on electromyographic (EMG) activity of lumbopelvic, including abdominal muscles. Surface EMG activity was collected from lumbar multifidus (LM), erector spinae (ES), internal oblique (IO), external oblique (EO) and rectus abdominis (RA) during overground walking (OW) and exercise device (EX) conditions. During walking, most muscles showed peaks in activity which were not seen during EX. Spinal extensors (LM, ES) were more active in EX. Internal oblique and RA were less active in EX. In EX, LM and ES were active for longer than during OW. Conversely, EO and RA were active for a shorter duration in EX than OW. The exercise device showed a phasic-to-tonic shift in activation of both local and global lumbopelvic muscles and promoted increased activation of spinal extensors in relation to walking. These features could make the exercise device a useful rehabilitative tool for populations with lumbopelvic muscle atrophy and dysfunction, including those recovering from deconditioning due to long-term bed rest and microgravity in astronauts.  相似文献   
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The origin and early evolution of membrane channels   总被引:3,自引:0,他引:3  
The origin and early evolution of ion channels are considered from the point of view that the transmembrane segments of membrane proteins are structurally quite simple and do not require specific sequences to fold. We argue that the transport of solute species, especially ions, required an early evolution of efficient transport mechanisms, and that the emergence of simple ion channels was protobiologically plausible. We also argue that, despite their simple structure, such channels could possess properties that, at the first sight, appear to require markedly greater complexity. These properties can be subtly modulated by local modifications to the sequence rather than global changes in molecular architecture. In order to address the evolution and development of ion channels, we focus on identifying those protein domains that are commonly associated with ion channel proteins and are conserved throughout the three main domains of life (Eukarya, Bacteria, and Archaea). We discuss the potassium-sodium-calcium superfamily of voltage-gated ion channels, mechanosensitive channels, porins, and ABC-transporters and argue that these families of membrane channels have sufficiently universal architectures that they can readily adapt to the diverse functional demands arising during evolution.  相似文献   
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模型化处理是飞行器测控工程的重要技术之一。文章以在轨自旋飞行器的姿态运动为研究对象,采用动力学分析的方法,不仅实现了姿态角演化微分方程与转动角速度微分方程的严格解耦,而且提出并建立带关联方程的动态-测量系统模型。基于该系统模型和扩展Kalman滤波/预报算法,建立了姿态角最优估计和转动角速度高精度估计算法。  相似文献   
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Preparations for the third UN Conference on the Exploration and Peaceful Uses of Outer Space (UNISPACE III) were intense. The conference itself was a success. But what forms will the follow-up take? Just reading the 150-page report is an effort in itself. Having played a central part in the preparations and organization, Europe fully appreciates the need to build on the spirit of cooperation which emerged from UNISPACE III. In November 1999, the European States gathered to analyze the results of the conference and to set a course for their future participation in the United Nations Programme on Space Applications (UNPSA), which is mainly done through ESA, and for their participation in the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS), which is done through coordination among ESA Member States. This article presents the authors’ personal accounts of the results of the European efforts around UNISPACE III and shows how ‘European foreign policy’ can work in international space policy. It also seeks to illustrate Europe's commitment to putting space technology to work for the benefit of development throughout the world.  相似文献   
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In a typical future mission a free flying platform will be released to space by Space Shuttle. After performing its active mission, it will have to wait for a suitable later Shuttle flight for retrieval at its original orbital altitude. To allow for the orbital descent during the total mission time of typically several months, one or several orbit raise manoeuvres have to be performed with the platform's own propulsion system. In the paper, the velocity-requirements Δv for these orbital transfers, depending on Sun activity, rendezvous-altitude, ballistic coefficient and longest expected mission time are treated.The simplest manoeuvre, consisting of one initial ascent transfer and one descent transfer at the actual retrieval date, is shown to be not optimal. Up to 25% of Δv can be saved, if several orbit raising transfers in a certain sequence are applied. A straightforward analytical treatment is presented for the optimization, while a computer program with the CIRA-atmosphere model is used for actual mission planning.  相似文献   
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This paper focuses on concepts and technologies required to develop a robotic air vehicle (RAV). A vehicle of this type has the capability to be a launch and forget weapon system. The authors are engineers and pilots so they view both the technical approach and piloting issues with equal importance. RAV must have the machine intelligence to make decisions within the mission and battlefield constraints. This requires a piloting expert system and route planner to perform passive terrain following, terrain avoidance, obstacle avoidance, and autonomous navigation based on low cost sensor inputs such as a multifunction FLIR, digital terrain map, and directional reference systems. RAV is a cost effective way to fight in a threat environment where aircrew loss rates would be unacceptable. RAV provides the Air Force a means to expand its combat capabilities.  相似文献   
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