A wide variety of terrestrial organisms, the so-called "anhydrobiotes," has learned to survive in a state of extreme dehydration in dry environments. Strategies for survival include the accumulation of certain polyols and nonreducing saccharides, which help to prevent damage to membranes and proteins, but at low water partial pressure DNA is also progressively damaged by various lesions, including strand breaks and cross-linking to proteins. These lesions, if they are not too numerous, can be repaired before the first replication step after rehydration, but long-term exposure to dry conditions finally diminishes the chances of survival as these lesions accumulate. If an organism has no chance to repair the accumulated DNA damage during intermittent periods of active life, survival will not exceed a few decades. The restriction of survival by dryness-induced DNA lesions is corroborated by new data on conidia of Aspergillus and the free plasmid pBR 322. Our results will be discussed with respect to the chance of finding dormant life or biochemical fossils on the surface of Mars. 相似文献
We evaluated the influence of prolonged weightlessness on the performance of visual tasks in the course of the Russian-French missions ANTARES, Post-ANTARES and ALTAIR aboard the MIR station. Eight cosmonauts were subjects in two experiments executed pre-flight, in-flight and post-flight sessions.
In the first experiment, cosmonauts performed a task of symmetry detection in 2-D polygons. The results indicate that this detection is locked in a head retinal reference frame rather than in an environmentally defined one as meridional orientations of symmetry axis (vertical and horizontal) elicited faster response times than oblique ones. However, in weightlessness the saliency of a retinally vertical axis of symmetry is no longer significantly different from an horizontal axis. In the second experiment, cosmonauts performed a mental rotation task in which they judged whether two 3-D objects presented in different orientations were identical. Performance on this task is basically identical in weightlessness and normal gravity. 相似文献
To study the possible effect of simulated weightlessness on brain function state, the brain event-related potentials (ERPs) in a simple visual selective response task were compared between HDT and HUT in 9 normal subjects. The results were: The Target(T) and non-Target(NT) flash signals both induced significant slow positive potentials which were supposed to related to the attention state; the amplitude of the positive potentials in frontal regions decreased significantly especially for NT-ERPs during HDT comprared with that during HUT. The data reported provide new evidence indicating that more attention should be paid on the brain function study during space flight. 相似文献
The objective of this investigation was to determine the acute responses to the electrolyte challenges under hypokinesia and physical exercise (PE) of different intensities with fluid and salt supplementation (FSS). The studies were performed on 12 physically healthy male volunteers aged 19-24 years under 364 days of hypokinesia (decreased number of steps per day) with a set of PE with FSS. The volunteers were divided into two equal groups. The first group was subjected to a set of intensive PE and the second group was submitted to a set of moderate PE. Both groups of subjects consumed daily water and salt supplements that aimed to increase the body hydration level. For simulation of the hypokinetic effect all subjects were kept under an average of 3000 steps per day. Functional tests with a potassium chloride (KCl) and calcium lactate (Cal) load were performed during the hypokinetic period of 364 days and the 60-day, prehypokinetic period that served as control, while both groups of subjects consumed daily calcium and potassium supplements. The concentration of electrolyte and hormone levels in the blood and their excretion rate in urine were determined. Renal excretion of calcium and potassium and the blood concentration thereof increased markedly in both groups of subjects. With the potassium chloride load tests the increased potassium excretion was accompanied by higher aldosterone and insulin blood levels, and with the calcium lactate load tests the increased calcium excretion was accompanied by a decreased parathyroid content in the blood. FSS and PE, regardless of intensity, failed to attenuate calcium and potassium losses. Additional intake of KCl and Cal also failed to normalize potassium and calcium abnormalities. It was concluded that during the KCl and Cal loading tests, the increased losses of potassium and calcium in the hypokinetic subjects were due to the inability of their bodies to retain these electrolytes, and that electrolyte abnormalities could not be reversed by PE or rehydration in individuals subjected to prolonged restriction of motor activity. 相似文献
A physical and a mathematical model of a working process in the pulsejet engine based on the analysis of the thermodynamic cycle are proposed. The process of self-sustained periodic combustion is connected with special features of elementary processes comprising the cycle, influencing the engine operation and depending on its design parameters. The calculation method is based on the use of fundamental laws of conservation and basic equations of gas dynamics 相似文献
We review the results obtained in the frequency range of Pc3 (22-100 mHz) and Pc4 (7-22 mHz) pulsations at Italian Antarctic
stations in the southern polar cap (“Mario Zucchelli”, at Terra Nova Bay, TNB, 80˚.S; “Concordia”, the Italian/French base at Dome C, DMC, 89˚.S). The absence of a midnight enhancement in the pulsation power suggests a negligible substorm influence at extreme latitudes,
while the sharp noon enhancement, which appears only at TNB, is determined by the closer proximity of the station to cusp
related phenomena. The relationship between the frequency of the band-limited signals and the interplanetary magnetic field
strength, the cone angle influence, and the higher correlation of the Pc3 power with the solar wind speed in the morning hours
suggest a global scenario in which upstream waves would be mainly responsible for the mid-frequency activity in the polar
cap. However, the polarization pattern is odd with respect to the predictions for tailward propagating modes. 相似文献
The radar designer must optimize parameters for performance in electronic countermeasures (ECM) and avoid any constraints which could be exploited by ECM. ECM/electronic counter-counter measures (ECCM) strategy must take into account electromagnetic compatibility (EMC) including enemy EMC. Electronic scanning improves search performance, but also reduces ECCM performance in other ways. While electronic scanning avoids some constraints, it imposes others, particularly in the frequency domain. It is argued that simple radars of good performance may be as cost effective in ECM as more complex systems. Some examples of recent developments are given. 相似文献
Current information on the neutral atmosphere of Jupiter is reviewed, with approximately equal emphasis on composition and thermal structure on the one hand, and markings and dynamics on the other. Studies based on Pioneer 10 and 11 data are used to refine the atmospheric model. Data on the interior are reviewed for the information they provide on the deep atmosphere. The markings and dynamics are discussed with emphasis on qualitative relationships and analogies with phenomena in the Earth's atmosphere.Contribution No. 2652 of the Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, Calif. 91125, U.S.A. 相似文献
An overview is given of ISO results on regions of high excitation ISM and gas, i.e. HII regions, the Galactic Centre and Supernova Remnants. IR emission due to fine-structure lines, molecular hydrogen, silicates,
polycyclic aromatic hydrocarbons and dust are summarised, their diagnostic capabilities illustrated and their implications
highlighted.
Based on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries:
France, Germany, The Netherlands, and the United Kingdom), and with the participation of ISAS and NASA. 相似文献