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511.
CEEF (Closed Ecology Experiment Facilities) were installed at Rokkasho village in northern Japan, for the purpose of clarifying life-support mechanisms in a completely closed space, such as a Lunar or Mars base. An integration test using the Closed Plantation Experiment Facility and Closed Animal Breeding & Habitation Experiment Facility is needed before conducting an entire closed experiment including plants, animals and humans. These integration tests are planned to be conducted step by step from fiscal 2001 to 2008.  相似文献   
512.
Although the elemental composition in all parts of the solar photosphere appears to be the same this is clearly not the case with the solar upper atmosphere (SUA). Spectroscopic studies show that in the corona elemental composition along solar equatorial regions is usually different from polar regions; composition in quiet Sun regions is often different from coronal hole and active region compositions and the transition region composition is frequently different from the coronal composition along the same line of sight. In the following two issues are discussed. The first involves abundance ratios between the high-FIP O and Ne and the low-FIP Mg and Fe that are important for meaningful comparisons between photospheric and SUA compositions and the second involves a review of composition and time variability of SUA plasmas at heights of 1.0≤h≤1.5R .  相似文献   
513.
    
Itapetinga measurements at 48 GHz with the multibeam technique are used to determine the relative position of solar burst centroid of emission with high spatial accuracy and time resolution. For the Great Bursts of October 19,22, 1989, with a large production of relativistic particles, and October 23, it is suggested that, at 48 GHz, the bursts might have originated in more then one source in space and time. Additionally the October 19 and 22 Ground Level Events exhibited very unusual intensity-time profiles including double component structures for the onset phase. The Bern observatory spectral radio emission data show a strong spectral flattening typical for large source inhomogeneties. The interpretation for this is that large solar flares are a superposition of a few strong bursts (separated both in space and time) in the same flaring region.  相似文献   
514.
  总被引:3,自引:0,他引:3  
Carcinogenesis is a multi-stage process with sequence of genetic events governing the phenotypic expression of a series of transformation steps leading to the development of metastatic cancer. In the present study, immortalized human bronchial (BEP2D) and breast (MCF-10F) cells were irradiated with graded doses of either 150 keV/micrometer alpha particles or 1 GeV/nucleon 56Fe ions. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Cell fusion studies indicated that radiation-induced tumorigenic phenotype in BEP2D cells could be completely suppressed by fusion with non-tumorigenic BEP2D cells. The differential expressions of known genes between tumorigenic bronchial and breast cells induced by alpha particles and their respective control cultures were compared using cDNA expression array. Among the 11 genes identified to be differentially expressed in BEP2D cells, three (DCC, DNA-PK and p21(CIP1)) were shown to be consistently down-regulated by 2 to 4 fold in all the 5 tumor cell lines examined. In contrast, their expressions in the fusion cell lines were comparable to control BEP2D cells. Similarly, expression levels of a series of genes were found to be altered in a step-wise manner among tumorigenic MCF-10F cells. The results are highly suggestive that functional alterations of these genes may be causally related to the carcinogenic process.  相似文献   
515.
Carcinogenesis is postulated to be a progressive multistage process characterized by an increase in genomic instability and clonal selection with each mutational event endowing a selective growth advantage. Genomic instability as manifested by the amplification of specific gene fragments is common among tumor and transformed cells. In the present study, immortalized human bronchial (BEP2D) cells were irradiated with graded doses of either 1GeV/nucleon 56Fe ions or 150 keV/μm alpha particles. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Tumorigenic cells showed neither ras mutations nor deletion in the p16 tumor suppressor gene. In contrast, they harbored mutations in the p53 gene and over-expressed cyclin D1. Genomic instability among transformed cells at various stage of the carcinogenic process was examined based on frequencies of PALA resistance. Incidence of genomic instability was highest among established tumor cell lines relative to transformed, non-tumorigenic and control cell lines. Treatment of BEP2D cells with a 4 mM dose of the aminothiol WR-1065 significantly reduced their neoplastic transforming response to 56Fe particles. This model provides an opportunity to study the cellular and molecular mechanisms involved in malignant transformation of human epithelial cells by heavy ions.  相似文献   
516.
Here we propose that the radioresistance (tolerance to ionizing radiation) observed in several terrestrial bacteria has a martian origin. Multiple inconsistencies with the current view of radioresistance as an accidental side effect of tolerance to desiccation are discussed. Experiments carried out 25 years ago were reproduced to demonstrate that \"ordinary\" bacteria can develop high radioresistance ability after multiple cycles of exposure to high radiation dosages followed by cycles of recovery of the bacterial population. We argue that \"natural\" cycles of this kind could have taken place only on the martian surface, and we hypothesize that Mars microorganisms could have developed radioresistance in just several million years' time and, subsequently, have undergone transfer to Earth by way of martian meteorites. Our mechanism implies multiple and frequent exchanges of biota between Mars and Earth.  相似文献   
517.
    
Space Science Reviews -  相似文献   
518.
The presence and movement of plasma density fluctuations in the F-region of the ionosphere are studied by monitoring phase and amplitude of radio waves propagating through the region. In this paper, we have used weak scattering theory and assumed the plasma density fluctuations to behave like phase changing diffraction screen. Appropriate relations for scintillation index S4, and phase variance δ? are derived and computed for different parameters of the plasma density irregularities of the ionosphere. SROSS-C2 satellite in situ measurements of plasma density fluctuations, which provide direct information about the structure and morphology of irregularities that are responsible for scintillation of radio waves, were used first time to develop a scintillation model for low latitude. It is observed that the scintillation index S4 and phase variance δ? depends on the strength of the plasma turbulence. Finally, the results obtained from modeling are compared and discussed with the available recent results.  相似文献   
519.
This paper examines the criteria for selecting the orbital and attitude prediction accuracy requirements for communications satellites. The accuracy requirements have been analyzed in terms of the various space operations involved, e.g., satellite acquisition, guidance and control, communications, telemetry, and command. It is hoped that the findings of this investigation will prove useful in satellite mission planning and design, thereby facilitating a judicious choice of the various satellite and ground components of the related subsystems.  相似文献   
520.
Adaptive pulse compression via MMSE estimation   总被引:2,自引:0,他引:2  
Radar pulse compression involves the extraction of an estimate of the range profile illuminated by a radar in the presence of noise. A problem inherent to pulse compression is the masking of small targets by large nearby targets due to the range sidelobes that result from standard matched filtering. This paper presents a new approach based upon a minimum mean-square error (MMSE) formulation in which the pulse compression filter for each individual range cell is adaptively estimated from the received signal in order to mitigate the masking interference resulting from matched filtering in the vicinity of large targets. The proposed method is compared with the standard matched filter and least-squares (LS) estimation and is shown to be superior over a variety of stressing scenarios.  相似文献   
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