Vestibular factors influencing the biomedical support of humans in space

This paper will describe the biomedical support aspects of humans in space with respect to the vestibular system. The vestibular system is thought to be the primary sensory system involved in the short-term effects of space motion sickness although there is increasing evidence that many factors play a role in this complex set of symptoms. There is the possibility that an individual's inner sense of orientation may be strongly coupled with the susceptibility to space motion sickness. A variety of suggested countermeasures for space motion sickness will be described. Although there are no known ground-based tests that can predict space motion sickness, the search should go on. The long term effects of the vestibular system in weightlessness are still relatively unknown. Some preliminary data has shown that the otoconia are irregular in size and distribution following extended periods of weightlessness. The ramifications of this data are not yet known and because the data was obtained on lower order animals, definitive studies and results must wait until the space station era when higher primates can be studied for long durations. This leads us to artificial gravity, the last topic of this paper. The vestibular system is intimately tied to this question since it has been shown on Earth that exposure to a slow rotating room causes motion sickness for some period of time before adaptation occurs. If the artificial gravity is intermittent, will this mean that people will get sick every time they experience it? The data from many astronauts returning to Earth indicates that a variety of sensory illusions are present, especially immediately upon return to a 1-g environment. Oscillopsia or apparent motion of the visual surround upon head motion along with inappropriate eye motions for a given head motion, all indicate that there is much to be studied yet about the vestibular and CNS systems reaction to a sudden application of a steady state acceleration field like 1-g. From the above information it is obvious that the vestibular system does have unique requirements when it comes to the biomedical support of space flight. This is not to say that other areas such as cardiovascular, musculo-skeletal, immunological and hematological systems do not have their own unique requirements but that possible solutions to one system can provide continuing problems to another system. For example, artificial gravity might be helpful for long term stabilization of bone demineralization or cardiovascular deconditioning but might introduce a new set of problems in orientation, vestibular conflict and just plain body motion in a rotating space vehicle.     

Disaster assessment and satellite communication: on the threshold of a new era

Disaster events have always been with us. Success or failure of a disaster response is often determined by timely access to communication and the exchange of reliable information. Especially, crucial is information acquired by on-site first responders responsible for initial disaster assessment. The rapid progress in satellite communication development is laying a foundation for a future where lack of communications will no longer be a limiting or paralyzing factor in disaster response. This paper discusses emerging satellite communications tools that can enhance on site assessment and change the way disaster management is viewed and carried out in the next century.     

Determination of the Attitude Motion of a Satellite Based on a Kinematical Model of Motion and Using Data of Measurements of Its Angular Velocity and the Earth’s Magnetic Field Strength

An integral statistical procedure of determination of the attitude motion of a satellite using the data of onboard measurements of angular velocity vectors and the strength of the Earth’s magnetic field (EMF) is suggested. The procedure uses only the equations of kinematics of a solid body and is applicable to determining both controlled and uncontrollable motions of a satellite at any external mechanical moments acting upon it. When applying this procedure, the data of measurements of both types, accumulated during a certain interval of time, are processed jointly. The data of measuring the angular velocity are smoothed by discrete Fourier series, and these series are substituted into kinematical Poisson equations for elements of the matrix of transition from a satellite-fixed coordinate system to the orbital coordinate system. The equations thus obtained represent a kinematical model of the satellite motion. The solution to these equations (which approximate the actual motion of a satellite) is found from the condition of the best (in the sense of the least squares method) fit of the data of measuring the EMF strength vector to its calculated values. The results of testing the suggested procedure using the data of measurements of the angular velocity vectors onboard the Foton-12 satellite and measurements of EMF strengths are presented.__________Translated from Kosmicheskie Issledovaniya, Vol. 43, No. 4, 2005, pp. 295–305.Original Russian Text Copyright © 2005 by Abrashkin, Volkov, Voronov, Egorov, Kazakova, Pankratov, Sazonov, Semkin.     

Supercooled water brines within permafrost-an unknown ecological niche for microorganisms: a model for astrobiology

This study describes brine lenses (cryopegs) found in Siberian permafrost derived from ancient marine sediment layers of the Arctic Ocean. The cryopegs were formed and isolated from sediment ~100,000-120,000 years ago. They remain liquid at the in situ temperature of -10 degrees C as a result of their high salt content (170-300 g/L). [(14)C] Glucose is taken up by the cryopeg biomass at -15 degrees C, indicating microbial metabolism at low temperatures in this habitat. Furthermore, aerobic, anaerobic heterotrophs, sulfate reducers, acetogens, and methanogens were detected by most probable number analysis. Two psychrophilic microbes were isolated from the cryopegs, a Clostridium and a Psychrobacter. The closest relatives of each were previously isolated from Antarctica. The cryopeg econiche might serve as a model for extraterrestrial life, and hence is of particular interest to astrobiology.     

Solving Optimization Problems for the Flight Trajectories of a Spacecraft with a High-Thrust Jet Engine in Pulse Formulation for an Arbitrary Gravitational Field in a Vacuum

A mathematically well-posed technique is suggested to obtain first-order necessary conditions of local optimality for the problems of optimization to be solved in a pulse formulation for flight trajectories of a spacecraft with a high-thrust jet engine (HTJE) in an arbitrary gravitational field in vacuum. The technique is based on the Lagrange principle of derestriction for conditional extremum problems in a function space. It allows one to formalize an algorithm of change from the problems of optimization to a boundary-value problem for a system of ordinary differential equations in the case of any optimization problem for which the pulse formulation makes sense. In this work, such a change is made for the case of optimizing the flight trajectories of a spacecraft with a HTJE when terminal and intermediate conditions (like equalities, inequalities, and the terminal functional of minimization) are taken in a general form. As an example of the application of the suggested technique, we consider in this work, within the framework of a bounded circular three-point problem in pulse formulation, the problem of constructing the flight trajectories of a spacecraft with a HTJE through one or several libration points (including the case of going through all libration points) of the Earth–Moon system. The spacecraft is launched from a circular orbit of an Earth's artificial satellite and, upon passing through a point (or points) of libration, returns to the initial orbit. The expenditure of mass (characteristic velocity) is minimized at a restricted time of transfer.     

Peculiarities of the Orbital Motion of Submicron Particles in the Earth's Plasmasphere

On the basis of numerical calculations of trajectories, the peculiarities of motion of submicron-sized particles in the Earth's plasmasphere are investigated. The most important result of these investigations is the found possibility of long-term residence of a microparticle in the Earth's vicinity. This effect is a result of the interaction of the electric charge, induced on a microparticle, with the magnetic field of the Earth. It is shown that the effect of microparticle capture by the Earth's magnetic field takes place in the case when the microparticles having a dimension of about 10^–2 m and made of a material having high yield of photoemission are injected into the plasmasphere at altitudes of about several thousand kilometers and also in the case when the microparticles with a dimension of about 10^–3 m and made of a material having low yield of photoemission are injected into the plasmasphere at altitudes of about 15000–20000 km and are moving close to the equatorial plane.     

Results of space experiment program "Interferon"

The results of the biological space experiment "Interferon" performed by two international cosmonaut teams (26 May 1980, and 16 May 1981) aboard space laboratory Solyut-6 are reported: (1) Human lymphocytes separated from blood of healthy donors and placed into "Interferon I" equipment could be kept for 7 days in suspension culture under spaceflight conditions. Interferon production could be induced in human lymphocytes by preparations of different origin: virus, synthetic polyribonucleotides, bacterial protein and plant pigment. An increased lymphocyte interferon production in space laboratory compared to ground control was observed. (2) Human interferon preparations and interferon inducers placed in space laboratory at room temperature for 7 days maintained their biological activity. (3) A decrease of induced interferon production and natural killer activity of lymphocytes isolated from peripheral blood of cosmonauts was observed on the 1st day on Earth after 7-days spaceflight.     

The space life sciences strategy for the 21st century

In the past, space life sciences has focused on gaining an understanding of physiological tolerance to spaceflight, but, for the last 10 years, the focus has evolved to include issues relevant to extended duration missions. In the 21st century, NASA's long-term strategy for the exploration of the solar system will combine the assurance of human health and performance for long periods in space with investigations aimed at searching for traces of life on other planets and acquiring fundamental scientific knowledge of life processes. Implementation of this strategy will involve a variety of disciplines including radiation health, life support, human factors, space physiology and countermeasures, medical care, environmental health, and exobiology. It will use both ground-based and flight research opportunities such as those found in current on-going programs, on Spacelab and unmanned biosatellite flights, and during Space Station Freedom missions.     

Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications.

An advanced, multiple projection, dual energy x-ray absorptiometry (AMPDXA) scanner system is under development. The AMPDXA is designed to make precision bone and muscle loss measurements necessary to determine the deleterious effects of microgravity on astronauts as well as develop countermeasures to stem their bone and muscle loss. To date, a full size test system has been developed to verify principles and the results of computer simulations. Results indicate that accurate predictions of bone mechanical properties can be determined from as few as three projections, while more projections are needed for a complete, three-dimensional reconstruction.     

Estimation of plasma density from wave data of cold electron plasma

Based on the dispersion relation of electron plasma, one can expect, that the waves excited in the frequency band (f_p, f_u=sqrt(f_p^*f_p+f_c^*f_c)) should persist in experimental spectra. For wave data from a spacecraft immersed in a cold plasma such an assumption may be misleading. In measurements performed on board the INTERCOSMOS-19, ACTIVE, APEX satellites and VC36.064CE rocket the most prominent spectral structure is centered around frequency f_r fulfilling the relation f_crp and corresponds to resonant detection of Bernstein waves excited in the surrounding plasma by spacecraft systems. Input network mismatch at frequencies around fu significantly depresses natural plasma noise as well as that excited by the spacecraft. Plasma emissions in the band (f_p, f_u) are prominent if the electromagnetic excitation is preferential (topside sounders) or if the excitation introduces nonequilibrium components into the plasma e.g. particle beams or clouds. Experimental examples are presented and parameters of cold plasma spectra useful for electron density estimation are discussed. The application to other spacecraft-cold plasma configurations is suggested.