High LET-induced H2AX phosphorylation around the Bragg curve.

We investigated the spatial distribution of the induction of the phosphorylated form of the histone protein H2AX (gamma-H2AX), known to be activated by DSBs. Following irradiation of human fibroblast cells with 600 MeV/nucleon silicon and 600 MeV/nucleon iron ions we observed the formation of gamma-H2AX aggregates in the shape of streaks stretching over several micrometers in an x/y plane. Polyethylene shielding was used to achieve a Bragg curve distribution with beam geometry parallel to the monolayer of cells. We present data that highlights the formation of immunofluorescent gamma-H2AX tracks showing the ion trajectories across the Bragg peak of irradiated human fibroblast cells. Qualitative analyses of these distributions indicated potentially increased clustering of DNA damage before the Bragg peak, enhanced gamma-H2AX distribution at the peak, and provided visual evidence of high-linear energy transfer particle traversal of cells beyond the Bragg peak in agreement with one-dimensional transport approximations. Spatial assessment of gamma-H2AX fluorescence may provide direct insights into DNA damage across the Bragg curve for high charge and energy ions including the biological consequences of shielding and possible contributors to bystander effects.     

Statistical description of low-latitude plasma blobs as observed by DMSP F15 and KOMPSAT-1

The global distribution of low-latitude plasma blobs was investigated by in-situ plasma density measurements from the Korea Multi-Purpose Satellite-1 (KOMPSAT-1) and Defense Meteorological Satellite Program (DMSP) F15. In the observations, blobs occurred in the longitude sector where the activity of the equatorial plasma bubble (EPB) was appreciable, and additional blobs were found at the lower (KOMPSAT-1) altitude as in the EPBs. However, several notable differences exist between the distributions of EPBs and blobs. First, KOMPSAT-1 found few blobs around 0°E in March and June, as did DMSP F15 from 30°W to 120°E for every season. Second, the overall occurrences in December and March at the DMSP F15 (840 km) altitude were somewhat lower than expected from those of the EBPs. Third, at the DMSP F15 altitude, the occurrence probability of plasma blobs was less controlled by yearly variations in the solar activity. These results imply that topside ionospheric conditions as well as the existence of EPBs control further development of blobs. Additionally, it was found that the blob latitudes became higher as the yearly solar activity increased. Moreover, most of the blobs were encountered in the winter hemisphere, possibly due to the low ambient density.     

Improving Avionics Fiber Optic Network Reliability & Maintainability

Work is ongoing at NAVAIR to understand how avionics fiber optic BIT technology can help reduce military aviation platform fiber optic network life cycle and total ownership cost. Operational availability enhancements via comprehensive supportability programs combined with keen attentiveness to reliability and maintainability metrics are driving the avionics fiber optic BIT value proposition. Avionics fiber optic BIT technology is expected to reduce failure rate and mean time to repair by predicting link failure before link failure actually occurs, running post-maintenance stress screening upon aircraft start-up, improving fault isolation by reducing the troubleshooting ambiguity zone from three to one, and reducing the need for separate support equipment for system troubleshooting     

First stage identification of syntactic elements in an extra-terrestrial signal

By investigating the generic attributes of a representative set of terrestrial languages at varying levels of abstraction, it is our endeavour to try and isolate elements of the signal universe, which are computationally tractable for its detection and structural decipherment. Ultimately, our aim is to contribute in some way to the understanding of what ‘languageness’ actually is. This paper describes algorithms and software developed to characterise and detect generic intelligent language-like features in an input signal, using natural language learning techniques: looking for characteristic statistical “language-signatures” in test corpora. As a first step towards such species-independent language-detection, we present a suite of programs to analyse digital representations of a range of data, and use the results to extrapolate whether or not there are language-like structures which distinguish this data from other sources, such as music, images, and white noise.     

A new US approach to human spaceflight?

In 2010 the administration of President Barack Obama proposed a dramatically new approach to future US human spaceflight. That new strategy was immediately controversial. This article traces the origins of the new spaceflight strategy and the continuing political debate with respect to its acceptance.     

RPC-MIP: the Mutual Impedance Probe of the Rosetta Plasma Consortium

The main objective of the Mutual Impedance Probe (MIP), part of the Rosetta Plasma Consortium (RPC), is to measure the electron density and temperature of Comet 67P/Churyumov-Gerasimenko’s coma, in particular inside the contact surface. Furthermore, MIP will determine the bulk velocity of the ionised outflowing atmosphere, define the spectral distribution of natural plasma waves, and monitor dust and gas activities around the nucleus. The MIP instrumentation consists of an electronics board for signal processing in the 7 kHz to 3.5 MHz range and a sensor unit of two receiving and two transmitting electrodes mounted on a 1-m long bar. In addition, the Langmuir probe of the RPC/LAP instrument that is at about 4 m from the MIP sensor can be used as a transmitter (in place of the MIP ones) and MIP as a receiver in order to have access to the density and temperature of plasmas at higher Debye lengths than those for which the MIP is originally designed.     

Sounding rocket experiment of bare electrodynamic tether system

An overview of a sounding rocket, S-520-25th, project on space tether technology experiment is presented. The project is prepared by an international research group consisting of Japanese, European, American, and Australian researchers. The sounding rocket will be assembled by the ISAS/JAXA and will be launched in the summer of 2009. The sounding rocket mission includes two engineering experiments and two scientific experiments. These experiments consist of the deployment of bare electrodynamic tape tether in space, a quick ignition test of hollow cathode system in space, the demonstration of bare electrodynamic tether system in space, and the test of the OML (orbital-motion-limit) current collection theory.