The Swift Ultra-Violet/Optical Telescope

The Ultra-Violet/Optical Telescope (UVOT) is one of three instruments flying aboard the Swift Gamma-ray Observatory. It is designed to capture the early (∼1 min) UV and optical photons from the afterglow of gamma-ray bursts in the 170–600 nm band as well as long term observations of these afterglows. This is accomplished through the use of UV and optical broadband filters and grisms. The UVOT has a modified Ritchey–Chrétien design with micro-channel plate intensified charged-coupled device detectors that record the arrival time of individual photons and provide sub-arcsecond positioning of sources. We discuss some of the science to be pursued by the UVOT and the overall design of the instrument.     

Characterizing the near-earth object hazard and its mitigation

Within observational constraints and analytic orbit determinations, potential NEO hazards and mitigations are characterized in terms of orbit displacements to establish (arbitrary) “safe” closest approach distances and corresponding energies that must be externally applied to achieve appropriate orbit displacements from the Earth. Required orbital velocity changes depend on projected closest Earth approach distances and time to (near) impact. Energy to achieve orbital displacement depends on NEO mass, required orbital velocity change, and the energy–momentum coupling coefficient. Errors in these parameters introduce uncertainties into hazard index and mitigation procedures. Hazard avoidance levels and mitigation indices for nine near-Earth asteroids, including 1997 XF₁₁ and 1999 AN₁₀, with non-zero Earth-impact probabilities are computed as examples of the proposed methodology, generating insight into the dilemma of predicting near impacts. This zeroth order approximation should not be construed as solving an orbital mechanics problem, nor establishing a particular set of criteria for mitigation action, but rather as a “survival index”.     

International involvement in the US space station programme

This article considers the issues surrounding the nature and extent of involvement in the US space station initiative. The motives and objectives of US cooperation with its allies are analysed from the perspective of both the USA and its potential partners. Guidelines for the forthcoming negotiations between these parties are elaborated through a review of past experience in international space cooperation. Developing a framework for collaboration will require significant trade-offs and will have to accommodate a number of not always consistent interests.     

Biosignatures from Earth-like planets around M dwarfs

Coupled one-dimensional photochemical-climate calculations have been performed for hypothetical Earth-like planets around M dwarfs. Visible/near-infrared and thermal-infrared synthetic spectra of these planets were generated to determine which biosignature gases might be observed by a future, space-based telescope. Our star sample included two observed active M dwarfs-AD Leo and GJ 643-and three quiescent model stars. The spectral distribution of these stars in the ultraviolet generates a different photochemistry on these planets. As a result, the biogenic gases CH4, N2O, and CH3Cl have substantially longer lifetimes and higher mixing ratios than on Earth, making them potentially observable by space-based telescopes. On the active M-star planets, an ozone layer similar to Earth's was developed that resulted in a spectroscopic signature comparable to the terrestrial one. The simultaneous detection of O2 (or O3) and a reduced gas in a planet's atmosphere has been suggested as strong evidence for life. Planets circling M stars may be good locations to search for such evidence.     

Long-term manipulations of intact microbial mat communities in a greenhouse collaboratory: simulating earth's present and past field environments

Photosynthetic microbial mat communities were obtained from marine hypersaline saltern ponds, maintained in a greenhouse facility, and examined for the effects of salinity variations. Because these microbial mats are considered to be useful analogs of ancient marine communities, they offer insights about evolutionary events during the >3 billion year time interval wherein mats co-evolved with Earth's lithosphere and atmosphere. Although photosynthetic mats can be highly dynamic and exhibit extremely high activity, the mats in the present study have been maintained for >1 year with relatively minor changes. The major groups of microorganisms, as assayed using microscopic, genetic, and biomarker methodologies, are essentially the same as those in the original field samples. Field and greenhouse mats were similar with respect to rates of exchange of oxygen and dissolved inorganic carbon across the mat-water interface, both during the day and at night. Field and greenhouse mats exhibited similar rates of efflux of methane and hydrogen. Manipulations of salinity in the water overlying the mats produced changes in the community that strongly resemble those observed in the field. A collaboratory testbed and an array of automated features are being developed to support remote scientific experimentation with the assistance of intelligent software agents. This facility will permit teams of investigators the opportunity to explore ancient environmental conditions that are rare or absent today but that might have influenced the early evolution of these photosynthetic ecosystems.     

Integrated design systems — capturing, reusing and optimizing design methods in new millennium

An important goal of New Millennium is to research new methods of performing spacecraft and mission design. We have completed the first phase of our effort on how to make design tools such as analysis programs more available. We are now embarking with Stanford University on discovering methods to allow more project history and knowledge to be automatically captured and reused and with Ames Research Center on how to use virtual reality to enhance the visualization of new missions before any hardware exists. We are also trying to capture the design process in an electronic form so that computer aided optimization may lead to a vastly greater search of the possible designs which meet the design requirements.     

Studies of radio frequency interference at Parkes Observatory

During 16 weeks of continuous SETI observing at the Parkes Observatory in New South Wales, Australia, a set of time-averaged data with 643 Hz resolution were recorded and returned to the SETI Institute for post-processing. These data are the 14 second (10 frame) average powers in each of 15,552 “subband” channels covering 10 MHz of the spectrum in both right and left circular polarizations that were used by the signal detection hardware to baseline and threshold the 1 Hz high resolution SETI spectra. The observations covered frequencies from 1.2 to 3 GHz, tracking 209 stellar targets across the sky. The data at each frequency were averaged over all directions and then interrogated to attempt to determine the prevalence of radio frequency interference (RFI). Estimates were made for the probability of encountering RFI at a particular frequency. Particular attention has been paid to those portions of the spectrum that are allocated as primary use status, or footnote protection for radioastronomy. This sixteen-week snapshot of the RFI situation at Parkes is by now out of date. Unfortunately, a year later, the situation has undoubtedly worsened.     

应用绿色半导体量子点进行乳腺癌原位成像

乳腺癌是癌症中引起妇女死亡的首要因素。本文采用绿色量子点作为荧光显色材料，建立了一种用于早期乳腺癌诊断的原位成像技术。利用生物素标记的抗HER2／neu抗体与乳腺癌细胞表面表达的HER2结合的特点，然后用偶联绿色量子点的链霉亲和素作为荧光检测标记物，与HER2抗原抗体复合物中的生物素发生特异结合，检测出乳腺癌细胞的存在。结果表明，在荧光显微镜下用绿色量子点原位显色的乳腺癌细胞，相对有机染料组显色亮度增强，故检测灵敏度有所提高。