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41.
In previous studies we used a ground based model to investigate the cellular responses to microgravity by exposing micromass cultures of embryonic limb cells to simulated weightlessness on a clinostat. Cultures set up in T-flasks and rotated at 30 rpm showed that clinostatted cultures had less chondrocyte differentiation than stationary or rotation controls, as assessed by number of nodules/culture stained with cartilage specific Alcian blue. In the current study, nodule size and shape of these nodules was assessed by interactive measurement of area, perimeter, circularity, and equivalent diameters, using the Optimas imaging software. Results show no significant difference in any of the measurements, indicating that clinorotation has no effect on expansion of the nodules either by differentiation of cells within the nodule, or by recruitment of cells into the nodule. The reduction in number of nodules without an alteration in size and shape indicates that the effect of simulated microgravity is to reduce the cell interactions required for the initial condensation of cells into a nodule, probably by interference with cell adhesion molecules.  相似文献   
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The planetary radio astronomy experiment will measure radio spectra of planetary emissions in the range 1.2 kHz to 40.5 MHz. These emissions result from wave-particle-plasma interactions in the magnetospheres and ionospheres of the planets. At Jupiter, they are strongly modulated by the Galilean satellite Io.As the spacecraft leave the Earth's vicinity, we will observe terrestrial kilometric radiation, and for the first time, determine its polarization (RH and LH power separately). At the giant planets, the source of radio emission at low frequencies is not understood, but will be defined through comparison of the radio emission data with other particles and fields experiments aboard Voyager, as well as with optical data. Since, for Jupiter, as for the Earth, the radio data quite probably relate to particle precipitation, and to magnetic field strength and orientation in the polar ionosphere, we hope to be able to elucidate some characteristics of Jupiter auroras.Together with the plasma wave experiment, and possibly several optical experiments, our data can demonstrate the existence of lightning on the giant planets and on the satellite Titan, should it exist. Finally, the Voyager missions occur near maximum of the sunspot cycle. Solar outburst types can be identified through the radio measurements; when the spacecraft are on the opposite side of the Sun from the Earth we can identify solar flare-related events otherwise invisible on the Earth.  相似文献   
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In order to stabilize the altitude calculation in an inertial navigation system, an altimeter is commonly used. In a conventional local-level mechanization, this is generally accomplished by correcting the vertical channel integrators with the difference between the inertial system and altimeter indication of vertical position. However, in a space-stable system the procedure is not as clear since a vertical channel is not physically present. Three altitude damping mechanizations for a space-stable inertial navigation system are proposed. The equivalent local-level mechanizations are then found by comparing error propagation equations in a common coordinate frame.  相似文献   
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In radars that achieve a high subclutter visibility by coherent processing over several pulses, a serious problem appears in the form of blind Dopplers, or ?speeds,? at which target detection is impossible. Of the possible methods of eliminating these blind speeds, the most basic one that is employed when the performance requirements are high involves the use of several PRF's. These PRF's are chosen so that coverage is obtained at any Doppler with at least one PRF. The problem faced by the radar designer is to select the set of PRF's and the pulse numbers for each PRF so that the search frame time is minimized. This paper evolves a systematic method for the design of the blind-speed elimination scheme. A formalized approach is offered that shows the possible combinations of wavelength, PRF, and pulse number and the tradeoffs involved, without introducing the confusion ordinarily associated with multiparameter choices.  相似文献   
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The Aerospace Corporation energetic electron-proton spectrometer operating on Applications Technology Satellite-6 (ATS-6) detects energetic electrons in four channels between 140 keV and greater than 32 MeV, and measures energetic protons in five energy channels between 2.3 and 80 MeV and energetic alpha particles in three channels between 9.4 and 94 MeV. After more than a year of operation in orbit, the experiment continues to return excellent data on the behavior of energetic magnetospheric electrons as well as information regarding the fluxes of solar protons and alpha particles.  相似文献   
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The aim of the proposed Beagle 2 small lander for ESA's 2003 Mars Express mission is to search for organic material on and below the surface of Mars and to study the inorganic chemistry and mineralogy of the landing site. The lander will have a total mass of 60kg including entry, descent, and landing system. Experiments will be deployed on the surface using a robotic arm. It will use a mechanical mole and grinder to obtain samples from below the surface, under rocks, and inside rocks. Sample analysis by a mass spectrometer will include isotopic analysis. An optical microscope, an X-ray spectrometer and a Mossbauer spectrometer will conduct in-situ rock studies.  相似文献   
48.
    
Beyond the magnetic influence of the Earth, the flux of galactic cosmic radiation (GCR) represents a radiological concern for long-term manned space missions. Current concepts of radiation quality and equivalent dose are inadequate for accurately specifying the relative biological \"efficiency\" of low doses of such heavily ionising radiations, based as they are on the single parameter of Linear Energy Transfer (LET). Such methods take no account of the mechanisms, nor of the highly inhomogeneous spatial structure, of energy deposition in radiation tracks. DNA damage in the cell nucleus, which ultimately leads to the death or transformation of the cell, is usually initiated by electrons liberated from surrounding molecules by the incident projectile ion. The characteristics of these emitted \"delta-rays\", dependent primarily upon the charge and velocity of the ion, are considered in relation to an idealised representation of the cellular environment. Theoretically calculated delta-ray energy spectra are multiplied by a series of weighting algorithms designed to represent the potential for DNA insult in this environment, both in terms of the quantity and quality of damage. By evaluating the resulting curves, and taking into account the energy spectra of heavy ions in space, a relative measure of the biological relevance of the most abundant GCR species is obtained, behind several shielding configurations. It is hoped that this method of assessing the radiation quality of galactic cosmic rays will be of value when considering the safety of long-term manned space missions.  相似文献   
49.
    
There were several cases when modulated electron beam had been injected from APEX satellite into an otherwise unmodified ionospheric plasma. The beams were formed from 2 μs pulses repeated at a rate of 40kHz. Injections took place in the altitude range 400–1100km over Europe. The onboard receiver connected to the dipole antenna swept the frequency interval 1–10 MHz in 1 sec. Due to a relatively narrow receiver bandwidth (15 kHz), moderate frequency step (50 kHz), slow changes of fn and fc (local electron plasma and gyro frequencies) fine structure of excited emissions was detected. In many cases, a very prominent doublet could be convincingly identified as a (fn,fu=sqrt(fn*fn+fc*fc)) band, with fn practically equal to the local plasma frequency in the unperturbed ionosphere. Determination of plasma frequency is of prime importance in analysis of complex structures composed from various harmonics fn,fc,fu. Complexity is manifested as coalescing of various harmonics with maxima shifted from nominal frequencies or splitting them into components due to mixing of local and propagation effects. Despite the existence of strong emissions on frequencies characteristic for the unperturbed ionosphere, very strong broadcasting transmissions are frequently cut off, even when the beam is directed upward. Most typical spectra are discussed.  相似文献   
50.
    
By using a Doppler Weather Radar (DWR) at Shriharikota (13.66°N & 80.23°E), an Artificial Neural Network (ANN) based technique is proposed to improve the accuracy of rain intensity estimation. Three spectral moments of a Doppler spectra are utilized as an input data to an ANN. Rain intensity, as measured by the tipping bucket rain gauges around the DWR station, are considered as a target values for the given inputs. Rain intensity as estimated by the developed ANN model is validated by the rain gauges measurements. With the help of a developed technique, reasonable improvement in the estimation of rain intensity is observed. By using the developed technique, root mean square error and bias are reduced in the range of 34–18% and 17–3% respectively, compared to ZR approach.  相似文献   
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