基于CFD技术的鼻腔输药的流动特性研究

鼻腔输药作为一种新颖的输药方式,具有方便可靠的特点,不仅可以适用于局部而且适用于全身用药,已经受到广泛的重视。但由于人类的呼吸道复杂的立体结构使得鼻腔输药成为生物医药研究的一个长期的挑战。利用CFD(计算流体动力学,Computational Fluid Dynamics)技术对鼻腔输药的流动特性进行研究,对一个基于真实的人类鼻腔解剖的3D模型的输药的流动过程进行了分析,着重研究了不同的药物颗粒的流动和沉淀特性。利用CFD的商用软件FLUENT在层流情况下对不同的密度、直径和流动速率的药物颗粒在鼻腔中流动进行了数值模拟,并对计算结果进行了比较分析。CFD研究的结果为鼻腔输药这种新颖的药物输送方式的优化设计提供了依据。     

INTESPACE试验中心为阿里安娜-V型火箭而进行的改造

文章介绍了法国宇航环境工程试验中心(INTESPACE)为满足阿里安娜-V的需要所准备进行的一系列改造.这些工作主要有:增建一个适合大型容器用的空气锁,保持厅内连续的10万级洁净度,建立一个紧凑试验区域,建造一面强效吸波墙,扩展振动设备能力以及改造原热真空设备.这些工作计划于2001年初全部完成.改造工作的完成将保证INTESPACE在独立的欧洲试验中心中继续处于领先地位.     

Solar Gamma-Ray Spectroscopy

Interactions of ions accelerated in solar flares produce gamma-ray lines and continuum and neutrons. These emissions contain a rich set of observables that provides information about both the accelerated ions and the environment where the ions are transported and interact. Ion interactions with the various nuclei present in the ambient medium produce gamma-ray lines at unique energies. How abundance information is extracted from the measurements is discussed and results from analyses of a number of solar flares are presented. The analyses indicate that the composition of the ambient gas where the ions interact (typically at chromospheric densities) is different from that of the photosphere and more like the composition of the corona, exhibiting low-FIP elemental enhancements that may vary from flare to flare. Evidence for increased Ne/O and the photospheric ³He abundance is also discussed.     

Onboard sensor orientation analysis with kriging method

We propose in this paper a method to analyse the efficiency of the direction pointed by an infrared sensor dedicated to forest fire detection on board of a space vehicle. The objective is to use these sensors to detect forest fires on a defined territory with a specified probability. One way to verify that the system stands this specification is to test each possible configuration (pointing direction of the sensor and number of space vehicles) and estimate the corresponding probability of forest fire detection. However, when the coverage territory is wide or when the number of vehicles is important, it is hardly possible to simulate every configuration in a reasonable amount of time. We propose to use kriging method for the prediction of forest fire detection probability for all possible configurations.     

Multiple moving target detection and trajectory estimation using a single SAR sensor

A novel methodology is presented for determining the velocity and location of multiple moving targets using a single strip-map synthetic aperture radar (SAR) sensor. The so-called azimuth position uncertainty problem is therefore solved. The method exploits the structure of the amplitude and phase modulations of the returned echo from a moving target in the Fourier domain. A crucial step in the whole processing scheme is a matched filtering, depending on the moving target parameters, that simultaneously accounts for range migration and compresses two-dimensional signatures into one-dimensional ones without losing moving target information. A generalized likelihood ratio test approach is adopted to detect moving targets and derive their trajectory parameters. The effectiveness of the method is illustrated with synthetic and real data covering a wide range of targets velocities and signal-to-clutter ratios (SCRs). Even in the case of parallel to platform moving target motion, the most unfavorable scenario, the proposed method yields good results for, roughly, SCR > 10 dB.     

Progress in ultrasonic bioreactors for CELSS applications.

An important issue in Controlled Ecological Life Support Systems (CELSS) is the recycling of inedible crop residues to recover inorganic plant nutrients such as nitrates, phosphates, potassium and other macro- and micro-nutrients. In a closed system in space, such regeneration is vital to the long term viability of plant growth necessary for the food production and waste handling process. Chemical approaches to recycling such as incineration and wet oxidation are not compatible with low energy and environmentally friendly regeneration of such nutrients. Biological regeneration is more acceptable environmentally, but it is a very slow process and does not typically result in complete recovery of inorganic and organic nutrients. A new approach to biological regeneration is described here involving the combined use of special enzymatic catalysts and ultrasonic energy in a bioreactor system. This new system has the potential for rapid, efficient, environmentally friendly and complete conversion of crop wastes to inorganic plant nutrients and food recovery from cellulose materials. A series of experimental tests were carried out with a soybean crop residue meal substrate. Biochemical conversion rates were significantly expedited with the addition of enzymes and further enhanced through ultrasonic stimulation of these enzymes. The difference in conversion rates was particularly increased after the initial period of soluble organics conversion. The remaining cellulose substrate is much more difficult to biodegrade, and the ultrasonically-enhanced reaction was able to demonstrate a much higher rate of substrate conversion.     

Mean winds of the mesosphere and lower thermosphere (60–110 km): A global distribution from radar systems (MF,Meteor, VHF)

During the last decade a large number of radars (～12) have been developed, which have produced substantial quantities of tidally-corrected mean winds data. The distribution of the radars is not global, but many areas are well covered: the Americas with Poker Flat (65°N), Saskatoon (52°N), Durham (43°N), Atlanta (34°N), Puerto Rico (18°N); Europe with Kiruna (68°), Garchy (47°N) and Monpazier (44°N); and Oceania with Christchurch (44°S), Adelaide (35°S), Townsville (20°S), and Kyoto (35°N). Zonal and meridional wind height-time cross-sections from $\text{60}\text{80}$ km (MF/Meteor Radar) to ～110 km have been prepared for the last 5–6 years. They are compared with cross-sections from CIRA-72 for zonal winds, and Groves (1969) for meridional winds.It is shown that while CIRA-72 is still a useful model for many purposes, significant differences exist between it and the new radar data. The latter demonstrate important seasonal, latitudinal, longitudinal and hemispheric variations. The new meridional cross-sections are of great value. The common features with Groves (1969) are the equatorward cells in summer near 85 km; however their strength (～10 ms^?1) and size are less. Systematic and somewhat different variations emerge at higher (?52°N) and middle (35–44°) latitudes.     

A new polyethylene balloon film

After over twenty years there is a new film introduced in the United States for fabricating scientific balloons. The film was developed by Raven and is designated Astrofilm.The film is a result of a critical selection of both the resin and extruding parameters. The film's physical properties and results of a test flight are reported. Also reported are a proposed design modification and failure analysis.     

Synthetic Environments for Simulated Missions

Synthetic environments offer Space Flight projects an opportunity to perform rapid, comprehensive, and rigorous modeling of the critical elements of a mission in order to compute quantitative measures of design performance, associated risk, and actual mission utility value. Significantly, these studies can be performed early in the mission cycle. These synthetic terrains are generated on parallel, high-performance computers and served to remote simulations at near-interactive speeds. The terrain creation uses a realistic sequence of physical phenomena such as cratering and dusting with parametric control of features such as surface roughness and rock density. Terrain resolution may be arbitrary but typically ranges from 0.01 to 10 meters. The terrain server has been used for two rover simulations, one using the actual Sojourner autonomy flight code, and the other a more general algorithm. Monte Carlo studies of rover designs interacting with synthetic environments were executed in parallel to quickly compute performance statistics and risk estimates.     

A low cost steerable radio-telescope

We present the technical characteristics of a low-cost radio telescope for solar/non solar observations at decimetric (1200–1700 MHz) and centimetric (2700 and 5000 MHz) wavelengths known as Brazilian Decimetric Array (BDA). The technical specifications of the antenna, tracking system, log-periodic feed, preamplifier and the frequency-synthesised receiver with a Single Side Band (SSB) video output of 2.5 MHz are given.