Paramecium--a model system for studying cellular graviperception.

Experiments under varied gravitational accelerations as well as in density-adjusted media showed that sensation of gravity in protists may be linked to the known principles of mechanosensation. Paramecium, a ciliate with clear graviresponses (gravitaxis and gravikinesis) is an ideal model system to prove this hypothesis since the ciliary activity and thus the swimming behaviour is controlled by the membrane potential. It has also been assumed that the cytoplasmic mass causes a distinct stimulation of the bipolarly distributed mechano-sensitive K+ and Ca2+ ion channels in the plasma membrane in dependence of the spatial orientation of the cell. In order to prove this hypothesis, different channel blockers are currently under investigation. Gadolinium did not inhibit gravitaxis in Paramecium, showing that it does not specifically block gravireceptors. Further studies concentrated on the question of whether second messengers are involved in the gravity signal transduction chain. Exposure to 5 g for up to 10 min led to a significant increase in cAMP.     

Electric currents induced inside biological cells by geomagnetic and atmospheric phenomena.

An increasing number of studies have appeared in the last ten years indicating that some pathologies may correlate with geomagnetic activity and cosmic rays. However a physical mechanism binding both phenomena has not been proposed. In the present work we obtain the amplitude of the magnetic fields at different frequencies, that may induce inside biological cells currents of the same magnitude of the currents generated by the cells themselves. We compare these values with the wave amplitudes produced in geomagnetic and atmospheric phenomena, and found that micropulsations, whistlers and lightning are capable of produce the same or larger values.     

Steady-state analysis and design of a switched-capacitor DC-DCconverter

A representative switched-capacitor DC-DC converter topology is presented, circuit operation is explained, and control strategies are identified. State-space averaging is used to analyze steady-state performance and to develop control criteria and design equations. The analytical results are verified by SPICE simulation     

The Freja ultraviolet imager

Auroral images acquired by satellite instrumentation have proven to be a crucial component of the scientific equiry into the physical processes of the Earth's magnetosphere. TheFreja mission provided an opportunity to extend these measurements into the temporal and spatial regime commonly associated with ground-based optical imagers. Employing the basic procedure used successfully in theViking program allowed image repetition rates of 6 s to be achieved with simultaneous exposure of all pixels within the field-of-view. Typical exposure times of 0.3 s required development of an improved image intensifier system and operational requirements resulted in image formats covering approximately one-third of a spin. Simultaneously exposing two broad-band UV cameras, the instrument generates in its normal operational mode 264.6 kbytes per image pair. Results from initial operations confirm the design approach and suggest such imagers can be routinely included on challenging low cost missions such asFreja.     

Implementation of hand geometry: an analysis of user perspectives and system performance

This discusses the implementation issues of installing a commercially available hand geometry system in the current infrastructure of Purdue University's Recreational Sports Center. In addition to a performance analysis of the system, a pre- and post-data collection survey was distributed to the 129 test subjects gathering information on perceptions of biometrics, in particular hand geometry, as well as participants' thoughts and feelings during their interaction with the hand geometry device. The results of the survey suggest that participants were accepting of hand geometry. Additionally, analyses of the participants' survey responses revealed that 93% liked using hand geometry, 98% thought it was easy to use, and 87% preferred it to the existing card-based system, while nobody thought the device invaded their personal privacy. System performance achieved a 3-try match rate of 99.02% (FRR 0.98%) when "gaming"/potential impostor attempts were removed from analysis. The failure to enroll rate was zero. Statistical analyses exposed a significant difference in the scores of attempts made by users with prior hand geometry usage, and subjects that could not straighten out their hand on the device. However, there were no statistical difference in the effects of rings/no rings, improper hand placements/proper hand placements, or gender on hand geometry score.     

Rationale for the development of the UK defence standards forsafety-critical computer software

Changes in the procurement environment and developments in technology that will require the adoption of new development certification procedures within the next few years are examined. Characteristics of safety-critical computer systems and the safety problems posed by digital computers are described. The way in which the changes have influenced the preparation of the new draft defence standards offered for public debate in the UK prior to their formal adoption by the Ministry of Defence is discussed. Principle features of the future safety-critical systems policy are outlined. The use of Ada for safety-critical software is considered     

A bioreactor system for the nitrogen loop in a Controlled Ecological Life Support System.

As space missions become longer in duration, the need to recycle waste into useful compounds rises dramatically. This problem can be addressed by the development of Controlled Ecological Life Support Systems (CELSS) (i.e., Engineered Closed/Controlled Eco-Systems (ECCES)), consisting of human and plant modules. One of the waste streams leaving the human module is urine. In addition to the reclamation of water from urine, recovery of the nitrogen is important because it is an essential nutrient for the plant module. A 3-step biological process for the recycling of nitrogenous waste (urea) is proposed. A packed-bed bioreactor system for this purpose was modeled, and the issues of reaction step segregation, reactor type and volume, support particle size, and pressure drop were addressed. Based on minimization of volume, a bioreactor system consisting of a plug flow immobilized urease reactor, a completely mixed flow immobilized cell reactor to convert ammonia to nitrite, and a plug flow immobilized cell reactor to produce nitrate from nitrite is recommended. It is apparent that this 3-step bioprocess meets the requirements for space applications.     

A SAR processor based on two-dimensional FFT codes

A synthetic aperture radar (SAR) processor approach based on two-dimensional fast Fourier transform (FFT) codes coupled with an asymptotic evaluation of the unit response function is presented. For the latter, no approximation is made to the distance function, so that the full range of geometric aberrations is analytically considered, enabling an effective reference filter to be designed. The two-dimensional FFTs were designed as to run on computers of very limited memory: the required FFT is computed by means of FFTs of lower order. Two FFT codes were considered: one is faster and allows full or reduced (quick look or multilook) resolution performance to be obtained easily; the second is slower but allows the use of a space-varying filter and/or investigations on limited portions (zoom) of the image. Both codes are suited to parallel processing, e.g. by a transputer net. A full discussion on computer memory and time requirements is presented as well as first examples of image processing results