A detailed study was made of the biological cleaning effectiveness, defined in terms of the ability to remove bacterial spores, of a number of methods used to clean hardware surfaces. Aluminum (Al 6061) and titanium (Ti 6Al-4V) were chosen for the study as they were deemed the two materials most likely to be used in spacecraft extraterrestrial sampler construction. Metal coupons (1 cm x 2.5 cm) were precleaned and inoculated with 5.8 x 10(3) cultivable Bacillus subtilis spores, which are commonly found on spacecraft surfaces and in the assembly environments. The inoculated coupons were subsequently cleaned using: (1) 70% isopropyl alcohol wipe; (2) water wipe; (3) multiple-solvent flight-hardware cleaning procedures used at the Jet Propulsion Laboratory (JPL); (4) Johnson Space Center-developed ultrapure water rinse; and (5) a commercial, semi-aqueous, multiple-solvent (SAMS) cleaning process. The biological cleaning effectiveness was measured by agar plate assay, sterility test (growing in liquid media), and epifluorescent microscopy. None of the cleaning protocols tested completely removed viable spores from the surface of the aluminum. In contrast, titanium was capable of being cleaned to sterility by two methods, the JPL standard and the commercial SAMS cleaning process. Further investigation showed that the passivation step employed in the JPL standard method is an effective surface sterilant on both metals but not compatible with aluminum. It is recommended that titanium (Ti 6Al-4V) be considered superior to aluminum (Al 6061) for use in spacecraft sampling hardware, both for its potential to be cleaned to sterilization and for its ability to withstand the most effective cleaning protocols. 相似文献
晶体控制的甚高频振荡器广泛应用于具有优良短期频率稳定度和低相位噪声的信号发生器中。这种振荡器均采用工作在泛音模的 AT 切晶体。由于 AT 切晶体谐振器的幅频效应,使相位噪声难以进一步减小。双旋转切晶体(例如 SC 切晶体)的幅频效应较 AT 切的小得多。因此,可使 SC 切晶体工作在较 AT 切晶体所允许的更大的激励电流上。如果能使振荡器固有的相位起伏不随晶体电流的增大而显著增大,则采用 SC 切晶体元件可以改善晶体控制甚高频信号发生器的短期频率稳定度和噪声。曾用三次泛音 SC 切晶体(而不是用五次泛音 AT 切晶体)进行过100MHz 低噪声振荡器的实际可行性试验。对 SC 切和 AT 切晶体元件的相频特性进行了测量。测量结果表明,晶体元件的功耗能够比使用 AT 切晶体增加6-10dB。对用双极结型晶体管振荡器的噪声源的检查表明,二次及三次失真是造成实际振荡器呈现显著相位闪变的原因。从解凡得堡(微分)方程中出现的频率校正项可了解到减小频率闪变的要求。桥式 T 形振荡器适合于作 SC 切甚高频晶体振荡维持电路。曾研究过这种电路的噪声源(包括调幅闪变噪声的幅相变换),并得到了对上述振荡器所预期的 L(f)的估算值。对相同的一对振荡器进行了测量,预计的 L(f)和所测得的 L(f)很一致。结果表明,和 AT 切甚高频晶体控制振荡器相比较,SC 切晶体控制的甚高频振荡器的L(f)得到了显著改善。 相似文献
The purpose of this study was to quantify the gas exchange between plants growing in a Closed Environmental Life Support System (CELSS) and the metabolism of human subjects undergoing various levels of physical exercise, and subsequently determine the buffer characteristics in relation to the carbon exchange established for plants in this closed loop life support system. Two men (ages 42 and 45 yr) exercised on a cycle ergometer at three different work intensities, each on a separate day. The CELSS, a 113 m3 chamber, was sized to meet the needs of one human. The plants, consisting of 20 m2 of potato, provided oxygen to the human during an artificially lighted photosynthesis phase and the human provided CO2 to the plants. The average rates of exchange for the subjects were 0.88, 1.69, and 2.47 liters O2/min and 0.77, 1.47, and 2.21 liters CO2/min at approximately 25%, 50%, and 75% of their maximal aerobic capacity, respectively. The photosynthetic rate for the CELSS was 0.95 liters/ min. A balance between human CO2 production and plant utilization was noted at approximately the 50% VO2max level. The oxygen balance and changes were not within detectable limits of the CELSS instrumentation for the durations of these exercise exposures. If a CELSS environment is the methodology selected for long term spaceflight, it will be important to select plants that efficiently grow at the available light and nutrient levels while balancing the needs for the human crew at their levels of physical activity. 相似文献
On February 7, 1994, four Canadian Astronauts were sealed off in a hyperbaric chamber at the Canadian Government's Defense and Civil Institute for Environmental Medicine in Toronto, Canada. This space lab training mission lasted seven days and was the first to be conducted with astronauts outside of Russia.
The objective of this mission was to give Canadian astronauts, space scientists and the staff of the Canadian Space Agency (CSA), the opportunity to gain first hand experience on preparational and operational aspects of a typical space mission. Twenty-one scientific experiments involving six countries from several disciplines were involved in this mission.
This paper describes the goals and preliminary results of a psychological experiment/training program that used the CAPSULS mission as a test bed for its application in the manned space flight environment. The objective of this project was to enhance the understanding of small group behaviour with a view to maximizing team effectiveness and task accomplishment in teams living and working in isolation under difficult and confined conditions. The application of this model in the light of future missions is a key thesis in this paper. 相似文献
The tail-cast suspension rat model has been developed in ground laboratories interested in space physiology for extensive study of mechanisms causing the pathophysiological syndrome associated with space flights. We used individually-caged male rats to explore the effects of acute and chronic (7d) orthostatic restraint (OR) and head-down anti-orthostatic restraint (AOR) on a series of physiological variables. The acute restraint study showed that (1) the installation of the OR device induced an acute reaction for 2 days, with a substantial rise in ACTH (x2) and CORT (x6), and that (2) the head-down tilt from OR to AOR induced (i) within 10 min and lasting 60 min a 2-fold rise in the intra-cerebro-ventricular pressure (Picv) monitored with an icv telemetric recording system, which receded to normal between 60 and 120 min; and (ii) within 30 min a short-lived 4-fold rise in plasma ACTH and CORT levels. Chronic OR induced (1) the suppression of the diurnal ACTH/CORT rhythm, with increased mean levels, especially for ACTH, (2) a degraded circadian locomotor activity rhythm manifested by a significant reduction in the spectral power of the 24h periodicity and a concomitant emergence of shorter (ultradian) periodicities, (3) an associated, but less pronounced alteration of the diurnal rhythm in body temperature; and (4) a marked increase in baseline plasma levels of IL-1β and an increased reactivity in cytokine release following an E. coli endotoxin (LPS) challenge. AOR induced (1) a similar obliteration of the circadian ACTH/CORT rhythm, (2) the loss of close correlation between ACTH and CORT, (3) a generalized increase in baseline plasma IL-1β levels and (4) more extensive degradation of the arcadian periodicity for both locomotor activity and, to a lesser extent, body temperature, replaced by dominant spectral powers for ultradian periodicities (3 to 10h). In conclusion, both experimental paradigms — but AOR more than OR — caused a blockade of the arcadian rhythmicity of major physiological variables, the loss of normal correlations between ACTH and CORT, and inflammatory-immune hyperreactivity. These pathophysiological disorders may all be parts of a complex chronic stress syndrome. 相似文献
Radiation hazard during previous manned space flights was not a critical problem as seen from monitoring on board MIR and the SHUTTLE. Future Martian and Lunar missions as well as flights on inclined or high altitude orbits around the Earth can be exposed to a large radiobiological risk and critical reliability losses can be expected, due to Single Event Effects on VLSI devices.
The mains characteristics of these hazards and some counter-measures to be provided for are given. 相似文献