Neutral buoyancy and sleep-deprived serum factors alter expression of cytokines regulating osteogenesis

We examined expression of genes associated with cytokine production, and genes implicated in regulating bone metabolism, in bone stromal and osteoblast cells incubated under standard ground conditions and under conditions of neutral buoyancy, and in the presence/absence of serum from normal or sleep-deprived mice. We observed a clear interaction between these two conditions (exposure to neutral buoyancy and serum stimulation) in promoting enhanced osteoclastogenesis. Both conditions independently altered expression of a number of cytokines implicated in the regulation of bone metabolism. However, using stromal cells from IL-1 and TNFx cytokine(r) KO mice, we concluded that the increased bone loss under microgravity conditions was not primarily cytokine mediated.     

Experimental support for an immunological approach to the search for life on other planets

We propose a three-phase approach to test for evidence of life in extraterrestrial samples. The approach capitalizes on the flexibility, sensitivity, and specificity of antibody-antigen interactions. Data are presented to support the first phase, in which various extraction protocols are compared for efficiency, and in which a preliminary suite of antibodies are tested against various antigens. The antigens and antibodies were chosen on the basis of criteria designed to optimize the detection of extraterrestrial biomarkers unique to living or once-living organisms.     

半导体式奌火系统

苏联,以乌里扬诺夫(列宁)命名的列宁格勒电工学院,电介质及半导体教研室 航空发动机的点火系统,大都采用了由磁电机来供电的高压火花放电式电咀。这种点水系统的结构复杂,体积笨重,并且在使用上还存在着严重的缺陷。这些缺陷,首     

我应邀参加美国冲击振动讨论会

应美国海军冲击振动情报中心主任蒲西(H·pusey)的邀请,北京强度环境研究所周锡仪、吴家驹二人出席了美国第52届冲击振动讨论会。会议由美国海军试验室冲击振动情报中心组织,美国国防部防核局和美军水路试验局主持,1981年10月26日至29日在美国新奥尔良城举行。来自美国、法国、加拿大、英国、澳大利亚、印度、瑞士和中国等国家的400多名     

在高频负荷下钛合金及耐热合金持久强度的研究

1.引言 新型优质材料的制造及其在工艺上的应用与金属疲劳强度问题的研究,关系极为密切。这一问题对于现代航空发动机构造的发展具有特别重要的意义。因为,这种发动机的零件是在高温和高频振动负荷的情况之下工作的。在喷气发动机中,负荷最大的零件     

用于飞机健康监控的传感器技术不断升级

得益于数据处理和存储技术的进步，从飞机上获取的数据量呈爆发式增长，可对飞机实施预测性维修的机会也越来越多。其中，不断进步的传感器技术是支撑飞机健康监控技术发展的关键因素。     

THE STUDY OF AIRPORTTERRAIN EFFECTS ON AUTOLAND FOR ANY AIRPLANE

<正> The terrain profile at several airports has caused some difficulty with autolands on the DC-10 and MD-80. Some operators have reported that the pilot had to disconnect the flight guidance system during flare and land manually. At present, the autoland guidance system is not uniquely designed to handle the variations of terrain. Since there is no accurate substitute for radio altitude(h_(rad)) the only variable left to improve is radio altitude rate (h_(rad)).     

钝尾物体底部压力计算

 提出了一种简便可靠的计算钝尾物体表面压力分布及底部压力的方法。将钝尾物体绕流流场分为无粘区、边界层区和分离区。无粘区和边界层区分别用位流理论和边界层理论计算。分离区由根据尾流函数等建立的替代模型模拟。利用奇点法解出整个模型的压力分布。计算釆用迭代法进行。对Vanwagenen模型和鲁尔大学模型进行了计算,结果表明该方法是成功的。