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931.
932.
Using a detector of near ultra-violet (UV) emission (wavelength range 300–400 nm) [1] onboard the Universitetsky-Tatiana satellite with an orbit height of 950 km and inclination of 81° we have detected and studied short UV flashes [2–5]. In this paper the observed UV flashes are classified according to the type of their time profiles, and the times of emission intensity rise and decay are investigated in every flash. Using the data on time profiles it turned out to be possible to estimate the flash energy in the atmosphere even in case of saturation of a signal measuring channel at the maximum of emission. The energy spectrum of observed flashes is estimated. Time and energy characteristics of the flashes are important for choosing a model of development of electric discharges in the upper atmosphere that are responsible for observed emission.  相似文献   
933.
Biochips are promising instruments for the search for organic molecules in planetary environments. Nucleic acid aptamers are powerful affinity receptors known for their high affinity and specificity, and therefore are of great interest for space biochip development. A wide variety of aptamers have already been selected toward targets of astrobiological interest (from amino acids to microorganisms). We present a first study to test the resistance of these receptors to the constraints of the space environment. The emphasis is on the effect of cosmic rays on the molecular recognition properties of DNA aptamers. Experiments on beam-line facilities have been conducted with 2 MeV protons and fluences much higher than expected for a typical mission to Mars. Our results show that this irradiation process did not affect the performances of DNA aptamers as molecular recognition tools.  相似文献   
934.
Reduced in vitro NK cytotoxic activity have routinely been observed after both prolonged and short-term space flights. This study investigated the effects of space flight on NK cell functions, NK cell counts and the production of IL-2 and TNF by lymphocytes of French-Russian crew members. In the French cosmonaut, after 21 days space flight, the cytotoxic activity of NK cells, the capacity the NK cells to bind and lyse the individual target cells and the percentage of NK cells were decreased. In this cosmonaut a twofold reduction TNF production in cultures of lymphocytes stimulated with PMA and with the mixture of PHA and PMA was observed on the first day after landing. However, the activity of the production of TNF in 48-hour PHA-cultures of lymphocytes was unchanged and the biological activity of IL-2 was not reduced. The immunological examination did not detecte any substantial deviations from the norm in both russian cosmonauts after 197 days space flight. Various explanations for decreased cytotoxicity in cosmonauts after space flight can be proposed, and these include the defective function of NK cells and reduced numbers of circulating effector cells.  相似文献   
935.
We studied microfluidity and selective ion permeability of plasma membranes and O2-binding properties of erythrocytes of cosmonauts during early rehabilitation after a long-term space flight (LTSF). Microfluidity of plasma membranes in surface regions was found to undergo a reversible decrease during 13–15 days following LTSF, which was accompanied by a reversible increase in relative cholesterol content. Cosmonauts’ erythrocytes revealed an increased activity of Na/H-exchanger and KCa-channel as well as a decrease in number of discocytes and increase in number of echinocytes, stomatocytes and knizocytes. Total hemoglobin content as well as oxyhemoglobin content were lowered after the LTSF, while the affinity of hemoglobin to O2 was advanced. It is suggested that the changes in Hb properties, microfluidity and selective permeability of plasma membranes following the elevated cholesterol content in the membranes can decrease tissue supply with O2.  相似文献   
936.
The mathematical model, which allowed us to reconstruct the rotational motion of the Bion M-1 and Foton M-4 satellites by processing the measurements of onboard magnetometers and the angular velocity sensor, is sufficiently detailed and accurate. If we slightly lower the requirements for accuracy and transfer to a rougher model, i.e., we will not update the biases in measurements of the angular velocity component, then the measurement processing technique can be significantly simplified. The volume of calculations in minimizing the functional of the least-square technique is reduced; the most complicated part of calculations is performed using the standard procedure of computational linear algebra. This simplified technique is described below, and the examples of its application for reconstructing the rotational motion of the Foton M-4 satellite are presented. A noticeable distinction in the reconstructions of motion, constructed by simplified and more exact techniques, is revealed in processing the measurements over time intervals longer than 4 hours.  相似文献   
937.
The spectral curve of the flux density of the radiation, which is reflected by the full moon towards the Earth’s ionosphere within a wavelength range of 200–1700 Å, has been presented. This curve is obtained by the approximation of space experiment data available in the scientific literature on the lunar spectral albedo and solar spectrum. Estimates of maximum values of spectral densities of fluxes reflected by the full moon in the neighborhood of wavelengths of ionization of basic ionospheric particles (neutral atoms of H I, He I, N I, O I, and Ar I and ions of He II, N II, O II, Ar II, N III, O III, and Ar III, as well as molecules of H2, N2, and O2) are given.  相似文献   
938.
A technique for calculation of the glow around low-orbit spacecraft is developed, taking into consideration the kinetics of neutral particles. Using this technique, the altitude ranges are determined where molecular processes dominate over ion-electron mechanisms. The influence of the molecular composition of the Earth’s atmosphere on the production of excited radicals NO 2 * near the surface of spacecraft is studied in some detail.  相似文献   
939.
This collaborative study is based on the analysis and comparison of results of coordinated experimental investigations conducted in Bulgaria and Azerbaijan for revealing a possible influence of solar activity changes and related geomagnetic activity variations on the human cardio-vascular state. Arterial blood pressure and heart rate of 86 healthy volunteers were measured on working days during a period of comparatively high solar and geomagnetic activity (2799 measurements in autumn 2001 and spring 2002) in Sofia. Daily experimental investigations of parameters of cardio-vascular health state were performed in Azerbaijan with a permanent group of examined persons. Heart rate and electrocardiograms were digitally registered (in total 1532 records) for seven functionally healthy persons on working days and Saturdays, in the Laboratory of Heliobiology at the Medical Center INAM in Baku, from 15.07.2006 to 13.11.2007. Obtained digital recordings were subjected to medical, statistical and spectral analyses. Special attention was paid to effects of solar extreme events, particularly those of November 2001 and December 2006. The statistical method of the analysis of variance (ANOVA) and post hoc analysis were applied to check the significance of the influence of geomagnetic activity on the cardio-vascular parameters under consideration. Results revealed statistically significant increments for the mean systolic and diastolic blood pressure values of the group with geomagnetic activity increase. Arterial blood pressure values started increasing two days prior to geomagnetic storms and kept their high values up to two days after the storms. Heart rate reaction was ambiguous and not significant for healthy persons examined (for both groups) under conditions with geomagnetic activity changes. It is concluded that heart rate for healthy persons at middle latitudes can be considered as a more stable physiological parameter which is not so sensitive to environmental changes while the dynamics of arterial blood pressure reveals a compensatory reaction of the human organism for adaptation.  相似文献   
940.
Some evidence indicates the deterioration of the cardiovascular system during space storms. It is plausible that the space weather conditions during and after hospital admission may affect the risk of coronary events in patients with acute coronary syndromes (ACS). We analyzed the data of 1400 ACS patients who were admitted to the Hospital Lithuanian University of Health Sciences, and who survived for more than 4 days. We evaluated the associations between geomagnetic storms (GS), solar proton events (SPE), and solar flares (SF) that occurred 0–3 days before and after hospital admission and the risk of cardiovascular death (CAD), non-fatal ACS, and coronary artery bypass grafting (CABG) during a period of 1 year; the evaluation was based on the multivariate logistic model, controlling for clinical data. After adjustment for clinical variables, GS occurring in conjunction with SF 1 day before admission increased the risk of CAD by over 2.5 times. GS 2 days after SPE occurred 1 day after admission increased the risk of CAD and CABG by over 2.8 times. The risk of CABG increased by over 2 times in patients admitted during the day of GS and 1 day after SPE. The risk of ACS was by over 1.63 times higher for patients admitted 1 day before or after solar flares.  相似文献   
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