Emesis and space motion sickness in amphibians.

Amphibians possess the ability to vomit in response to a variety of stimuli that provoke emesis in mammals. Pharmacological studies have establish that the ejection of gastric contents and the basic mechanism for vomiting have been phylogenetically conserved among these tetrapods. As part of on-going comparative studies on emesis in vertebrates, we previously documented that some postmetamorphic anurans and salamander larvae experience motion-induced emesis when exposed to the provocative stimulus of parabolic aircraft flight. However, more recent experiments suggest that there are strict conditions for inducing emesis in amphibians exposed to parabolic flight and that amphibians are not as sensitive to this stimulus as mammals. Further studies on emesis in lower vertebrates may help us understand the processes that cause emesis in abnormal gravitational regimes.     

The human cardiovascular system during space flight

Purpose of the work is to analyze and to summarize the data of investigations into human hemodynamics performed over 20 years aboard orbital stations Salyut-7 and Mir with participation of 26 cosmonauts on space flights (SF) from 8 to 438 days in duration. The ultrasonic techniques and occlusive plethysmography demonstrated dynamics of changes in the cardiovascular system during SF of various durations. The parameters of general hemodynamics, the pumping function of the heart and arterial circulation in the brain remained stable in all the space flights; however, there were alterations in peripheral circulation associated with blood redistribution and hypovolemie in microgravity. The anti-gravity distribution of the vascular tone decayed gradually as unneeded. The most considerable changes were observed in leg vessels, equally in arteries (decrease in resistance) and veins (increase in maximum capacity). The lower body negative pressure test (LBNP) revealed deterioration of the gravity-dependent reactions that changed for the worse as SF duration extended. The cardiovascular deconditioning showed itself as loss of descent acceleration tolerance and orthostatic instability in the postflight period.     

Harnessing functional food strategies for the health challenges of space travel—Fermented soy for astronaut nutrition

Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.     

Additional Measurements on Pit Shielding for Communications Satellite Earth Stations

This correspondence reports measurements taken in both the 4- and 6-GHz frequency bands of the protection afforded a pit-shielded Earth-station antenna. The measurement program described is an expansion of a previous one and was designed to determine the effects of artificial site shielding for a range of satellite locations rather than a single position.     

“Modular Biospheres” – New testbed platforms for public environmental education and research

This paper will review the potential of a relatively new type of testbed platform for environmental education and research because of the unique advantages resulting from their material closure and separation from the outside environment. These facilities which we term “modular biospheres”, have emerged from research centered on space life support research but offer a wider range of application. Examples of this type of facility include the Bios-3 facility in Russia, the Japanese CEEF (Closed Ecological Experiment Facility), the NASA Kennedy Space Center Breadboard facility, the Biosphere 2 Test Module and the Laboratory Biosphere. Modular biosphere facilities offer unique research and public real-time science education opportunities. Ecosystem behavior can be studied since initial state conditions can be precisely specified and tracked over different ranges of time. With material closure (apart from very small air exchange rate which can be determined), biogeochemical cycles between soil and soil microorganisms, water, plants, and atmosphere can be studied in detail. Such studies offer a major advance from studies conducted with phytotrons which because of their small size, limit the number of organisms to a very small number, and which crucially do not have a high degree of atmospheric, water and overall material closure. Modular biospheres take advantage of the unique properties of closure, as representing a distinct system “metabolism” and therefore are essentially a “mini-world”. Though relatively large in comparison with most phytotrons and ecological microcosms, which are now standard research and educational tools, modular biospheres are small enough that they can be economically reconfigured to reflect a changing research agenda. Some design elements include lighting via electric lights and/or sunlight, hydroponic or soil substrate for plants, opaque or glazed structures, and variable volume chambers or other methods to handle atmospheric pressure differences between the facility and the outside environment.     

XMM-Newton study of soft excess X-ray emission in clusters of galaxies

We discuss the detection of soft excess X-ray emission in a sample of 19 clusters of galaxies observed by XMM-Newton. In 6/19 clusters evidence for a soft X-ray excess is found. Four of these clusters show soft X-ray and O VII line emission from gas with a temperature of 0.2 keV. The centroid of this oxygen line is consistent with the redshift of the cluster. The intensity and spatial extend of the soft excess agrees with previous PSPC measurements. These observations are interpreted as emission from warm-hot intergalactic medium filaments, with density enhancements near the cluster centers, consistent with theoretical predictions. In the other two soft excess clusters a non-thermal origin is consistent with the data.     

Amplitude modulation of VLF emission and absorption of cosmic noise by <Emphasis Type="Italic">Pc</Emphasis>5 geomagnetic pulsations in the period of geomagnetic storms on October 30–31, 2003

Modulation of the VLF emission and riometric absorption by Pc5 geomagnetic pulsations is studied in the period of strong geomagnetic disturbances on October 30–31, 2003. Some conclusions about the regime of pitch-angular diffusion into the loss cone are made. The better coincidence of VLF emission modulation with geomagnetic pulsations in other longitude sectors is explained by the global character of excitation of the pulsations and by damping of their amplitudes at the meridian of observation of the VLF emission, which is associated with intensification of auroral electrojets.Translated from Kosmicheskie Issledovaniya, Vol. 42, No. 6, 2004, pp. 632–639.Original Russian Text Copyright © 2004 by Solovyev, Mullayarov, Baishev, Barkova, Samsonov.     

On the problem of lunar radiation environment

In connection with projects of manned bases on the Moon it becomes topical to estimate radiation danger for their inhabitants. In this paper we describe a method of evaluation of the radiation environment on the lunar surface produced by galactic and solar cosmic rays. The roles of both primary and secondary radiations generated in the depth of the lunar soil under the action of high-energy protons and nuclei are taken into account. Calculated fluxes of particles are used in order to estimate annual averaged absorbed and equivalent local dose rates in tissues. It is established that in the lunar rock the contribution of secondary neutrons to the dose rate exceeds that of protons. The contribution of the secondary particles generated by nuclei of galactic cosmic rays to the dose rate is estimated.     

Fifty Years of Cosmic Radiation Data

Cosmic radiation has been measured by a variety of techniques since 1933. This paper presents the evolution of data acquisition, processing, and availability of cosmic radiation data from the early years to the present time. Information on the worldwide network of neutron monitor stations and the availability of these cosmic radiation records is included. This revised version was published online in August 2006 with corrections to the Cover Date.