排序方式: 共有49条查询结果,搜索用时 15 毫秒
11.
E J Hall D J Brenner B Worgul L Smilenov 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2005,35(2):249-253
In the context of space radiation, it is important to know whether the human population includes genetically predisposed radiosensitive subsets. One possibility is that haploinsufficiency for ATM confers radiosensitivity, and this defect involves 1-3% of the population. Using knock-out mice we chose to study cataractogenesis in the lens and oncogenic transformation in mouse embryo fibroblasts to assay for effects of ATM deficiency. Radiation induced cataracts appeared earlier in the heterozygous versus wild-type animals following exposure to either gamma rays or 1 GeV/nucleon iron ions. In addition, it was found that embryo fibroblasts of Atm heterozygotes showed an increased incidence of oncogenic transformation compared with their normal litter-matched counterparts. From these data we suggest that Ataxia Telangiectasia heterozygotes could indeed represent a societally significant radio sensitive subpopulation. Knock-out mice are now available for other genes including BRCA1 and 2, and Mrad9. An exciting possibility is the creation of double heterozygotes for pairs of mutated genes that function in the same signal transduction pathway, and consequently confer even greater radiosensitivity. 相似文献
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Boundary layers in three dimensions 总被引:1,自引:0,他引:1
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Fairchild Defense, a division of Orbital Sciences Corporation, has been a pioneer in the use of Commercial-Off-The-Shelf (COTS) hardware, software, and tools in military equipment. Fairchild has developed a cost and schedule effective approach to the use of COTS elements. This paper discusses Fairchild's experience with the use of COTS in military equipment and special considerations imposed because of the military environment 相似文献
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Boerner Wolfgang-M. Cole James B. Goddard William R. Tarnawecky Michael Z. Shafai Lotfallah Hall Donald H. 《Space Science Reviews》1983,36(2):195-205
A sensitive search for pulsars inside a sample of gamma-ray source error boxes has been carried out using the Arecibo and Parkes radiotelescopes. The paper describes the motivation of this search and the characteristics of the experiments used. As a preliminary result, new pulsars have been discovered and some of them are possibly candidates to be the counterparts of the gamma-ray sources. 相似文献
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J.N. Carter G. Frye C.J. Hall T.L. Jenkins A. Owen D. Ramsden 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1983,3(4):49-52
Recent tests of a γ-ray imaging telescope, which incorporated a coded aperture mask and multi-wire proportional counter system produced good images of a tritium target source which was used to generate the 20 MeV protons at a proton Van de Graaff accelerator. This paper indicates what performance one might expect if a large area drift chamber were used in conjunction with a coded aperture mask. The prospects for achieving significant scientific results if such a system were flown on a variety of space vehicles are discussed. 相似文献
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An industry-based pragmatic review is provided of the economic and product-quality consequences of automatic test equipment (ATE) usage in printed circuit board testing. The company selection process, the nature of the industrial participants, and the data collection process are described. The benefits obtained by users are identified. It is demonstrated that the use of ATE systems does result in definable economic and quality-level benefits 相似文献
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Douglas S. Hall 《Space Science Reviews》1989,49(3-4):219-233
Late-type secondaries in Algol binaries are rapidly rotating convective stars and thus should be chromospherically active (CA). They are examined with respect to observational manifestations which characterize already known CA stars: Ca II H and K emission cores, photometric variability attributable to starspots, soft x-ray emission, non-thermal radio emission, ultraviolet and infrared excess, and alternating period changes. The conclusion is that they can be regarded as another class of CA stars. In most respects they are literally indistinguishable from other CA stars. Ca II H and K emission cores are observed in the lobe-filling component of six semi-detached binaries: U Cep, RT Lac, RV Lib, AR Mon, S Vel, HR 5110. Alternating period changes are shown to occur only in Algols containing a late-type (convective) star. It is proposed, therefore, that the Matese-Whitmire mechanism explains these changes. Specifically, the interval from one increase (or decrease) to the next can be equated with the star's magnetic cycle. Cycle lengths for 31 stars, derived in this way, range between 7 years and 109 years, with a median of 50 years. 相似文献
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J.L. Hall A.H. Yavrouian V.V. Kerzhanovich T. Fredrickson C. Sandy Michael T. Pauken E.A. Kulczycki G.J. Walsh M. Said S. Day 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2011
This paper describes the results of ongoing technology development activities for a Venus spherical superpressure balloon capable of flying for long durations (30 days) in the middle cloud layer at an altitude of 55.5 km. Data is presented from a successful aerial deployment and inflation flight experiment on a 5.5 m diameter prototype balloon conducted at a 2.5 km altitude above the Earth. Although the balloon in that test was not released for free flight, all other steps in the deployment and inflation process were successfully executed. Experimental and computational results are also presented from an investigation of the stress concentration phenomenon at the junction of the metal end fitting and fabric end cap of the prototype Venus balloon. Good agreement was found between the simulation and experimental results and a stress concentration factor of 1.55 determined for this end cap design compared to the expectations of thin membrane theory. Finally, results are presented for a new, second-generation Venus balloon material utilizing Aclar™ film instead of Teflon. Optical property and sulfuric acid tolerance data are presented for this material based on laboratory testing of samples. 相似文献