A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model.

When applied to the Colorado Plateau miner population, the two-stage clonal expansion (TSCE) model of radiation carcinogenesis predicts that radiation-induced promotion dominates radiation-induced initiation. Thus, according to the model, at least for alpha-particle radiation from inhaled radon daughters, lung cancer induction over long periods of protracted irradiation appears to be dominated by radiation-induced modification of the proliferation kinetics of already-initiated cells rather than by direct radiation-induced initiation (i.e., mutation) of normal cells. We explore the possible consequences of this result for radiation exposures to space travelers on long missions. Still unknown is the LET dependence of this effect. Speculations of the cause of this phenomenon include the suggestion that modification of cell kinetics is caused by a "bystander" effect, i.e., the traversal of normal cells by alpha particles, followed by the signaling of these cells to nearby initiated cells which then modify their proliferation kinetics.     

The image/poetry education and public outreach program

Education and public outreach are viewed by NASA as significant undertakings for all of its space missions. The IMAGE satellite is one of the first missions to explicitly include `E&PO in its original proposal to NASA in 1996. We will discuss what IMAGE has accomplished in this area to date, and what new activities it will conduct following a successful launch.     

The Kinelite Project: a new powerful motion analyser for Spacelab and space station

The goal of the Kinelite Project is to develop a space qualified motion analysis system to be used in space by the scientific community, mainly to support neuroscience protocols. The measurement principle of the Kinelite is to determine, by triangulation mean, the 3D position of small, lightweight, reflective markers positioned at the different points of interest. The scene is illuminated by Infra Red flashes and the reflected light is acquired by up to 8 precalibrated and synchronized CCD cameras. The main characteristics of the system are: Camera field of view: 45 degrees; Number of cameras: 2 to 8; Acquisition frequency: 25, 50, 100, or 200 Hz; CCD format: 256 x 256; Number of markers: up to 64; 3D accuracy: 2mm; Main dimensions: 45 cm x 45 cm x 30 cm; Mass: 23 kg; Power consumption: less than 200 W. The Kinelite will first fly aboard the NASA Spacelab; it will be used, during the NEUROLAB mission (4/98), to support the "Frames of References and Internal Models" (Principal Investigator: Pr. A. Berthoz, Co Investigators: J. McIntyre, F. Lacquaniti).     

Prototype design and testing of a Venus long duration,high altitude balloon

This paper describes the design, fabrication and testing of a full scale prototype balloon intended for long duration flight in the upper atmosphere of Venus. The balloon is 5.5 m in diameter and is designed to carry a 45 kg payload at an altitude of 55 km. The balloon material is a 180 g/m² multi-component laminate comprised of the following layers bonded together from outside to inside: aluminized Teflon film, aluminized Mylar film, Vectran fabric and a polyurethane coating. This construction provides the required balloon functional characteristics of low gas permeability, sulfuric acid resistance and high strength for superpressure operation. The design burst superpressure is 39,200 Pa which is predicted to be 3.3 times the worst case value expected during flight at the highest solar irradiance in the mission profile. The prototype is constructed from 16 gores with bi-taped seams employing a sulfuric acid resistant adhesive on the outside. Material coupon tests were performed to evaluate the optical and mechanical characteristics of the laminate. These were followed by full prototype tests for inflation, leakage and sulfuric acid tolerance. The results confirmed the suitability of this balloon design for use at Venus in a long duration mission. The various data are presented and the implications for mission design and operation are discussed.     

Electromagnetic waves observed by Venus Express at periapsis: Detection and analysis techniques

The magnetometer on Venus Express was designed to be able to obtain 128 Hz samples of the magnetic field from two sensors in a gradiometer configuration. This mode is used around periapsis to determine whether the signals reported at low altitudes near 100 Hz, had the properties of electromagnetic waves generated by electric discharges in the Venus atmosphere. The lack of a magnetic cleanliness program and the shortness of the magnetometer boom make this a challenging measurement. Fortunately the signals are sufficiently strong that they can be easily resolved with rather straightforward analysis techniques.     

On the electrodynamics of counter stream in pulsar’s inner annular cap region

The electric properties of pulsar’s inner annular gap are explored in this paper. Under two main assumptions, (1) the pulsar is alive, (2) the total charge of pulsar should not vary with time, the condition for the acceleration of negative particle in the annular region is derived. The acceleration condition is j₋ ? 0.5j₊, i.e., the current carried by negative particles is greater than or equal to 0.5 times of the current carried by positive particles. This condition holds even when the backward flow of positive particles exists in the annular region. It is noted that the outflow of negative particles offers good opportunities to understand the current closure problem of pulsar as well as wide radiation beam of pulsar observed at high energy band.     

Radar network system to observe & analyze Tokyo Bay vessel traffic

A complete grasp of the actual vessel traffic flow by accurate observation is essential to carry out vessel traffic management, design of vessel traffic route, plan of port construction, etc. Up to now, the observation of vessel traffic has needed many efforts such as the use of a special ship or car equipped with radar observation systems and the observation staff preparation for a considerably long period. In order to perform accurate observation of vessel traffic without such efforts, the authors have developed a completely automated radar network system covering the main traffic route of Tokyo Bay. In August 2003, as the second remote radar station attaching AIS equipment was set at East Ogishima (the first was installed at the National Defense Academy in 2002), the observing range could be enlarged and cover most traffic routes in Tokyo Bay. These two radars can observe the vessel traffic in Tokyo Bay simultaneously so as to know the traffic flow accurately on the basis of analyzing the integrated radar data. In addition to the development of a radar network system, the software to analyze observed vessel traffic flow has been developed. This software has various functions such as tracking of ship's position, automatic determination of ship's size, animation of ship's movements, superposition of successive radar images, display of ship's tracks, calculation of ship's speed distribution, extraction of dangerous ship encounters using subjective judgment value and bumper model, etc. Some analyzed results on vessel traffic flow observed by the remote radars in January and September 2003 are shown in this paper.     

Lunar-based enterprise infrastructure—hidden keys for long-term business success

Discussions on the creation of lunar bases or Moon-based industrial operations tend to focus on large issues i.e. transportation, cost, and/or sustainability. But assume that the fledging lunar enterprise is successful and engenders other Moon-based operations that also grow in terms of size and scope. Could success become more problematic than failure if some often minimized, yet essential, requirements for long-term human occupation of the Moon were ignored? This paper looks at lunar operations in terms of what will be required for long-term success as participants come to view themselves as terrestrial expatriates rather than engaged in short-term duty assignments.