Probability of cell hits in selected organs and tissues by high-LET particles at the ISS orbit.

The fluence of high-LET particles (HLP) with LET infinity H2O greater than 15 keV micrometers-1 in selected organs and tissues were measured with plastic nuclear track detectors using a life-size human phantom on the 9th Shuttle-Mir Mission (STS-91). The planar-track fluence of HLP during the 9.8-day mission ranged from 1.9 x 10(3) n cm-2 (bladder) to 5.1 x 10(3) n cm-2 (brain) by a factor of 2.7. Based on these data, a probability of HLP hits to a matured cell of each organ or tissue was roughly estimated for a 90-day ISS mission. In the calculation, all cells were assumed to be spheres with a geometric cross-sectional area of 500 micrometers2 and the cell-hit frequency from isotropic space radiation can be described by the Poisson-distribution function. As results, the probability of one or more than 1 hit to a single cell by HLP for 90 days ranged from 17% to 38%; that of two or more than 2 hits was estimated to be 1.3-8.2%.     

Indirect search for Dark Matter with H.E.S.S.

Observations of the Galactic center region with the H.E.S.S. telescopes have established the existence of a steady, extended source of gamma-ray emission coinciding with the position of the super massive black hole Sgr A^*. This is a remarkable finding given the expected presence of dense self-annihilating Dark Matter in the Galactic center region. The self-annihilation process is giving rise to gamma-ray production through hadronization including the production of neutral pions which decay into gamma-rays but also through (loop-suppressed) annihilation into final states of almost mono-energetic photons. We study the observed gamma-ray signal (spectrum and shape) from the Galactic center in the context of Dark Matter annihilation and indicate the prospects for further indirect Dark Matter searches with H.E.S.S.     

A space radiation transport method development.

Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design.     

Analysis of an adaptive algorithm for unbiased multipath time delay estimation

The multipath equalization time delay estimator (METDE) provides an adaptive approach for estimating the difference in arrival times of a signal received at spatially separated sensors as well as the multipath channel characteristics. However, the parameter estimates of the METDE are biased in the presence of noise. The METDE algorithm is improved for unbiased parameter estimation via minimizing a modified cost function. Convergence behaviors and variances of the system variables of the amended method are derived. Computer simulations are included to corroborate the theoretical analysis and to evaluate the adaptive multipath delay estimation performance of the proposed algorithm.     

The Sun–Earth Connection in Time Scales from Years to Decades and Centuries

The Sun–Earth connection is studied using long-term measurements from the Sun and from the Earth. The auroral activity is shown to correlate to high accuracy with the smoothed sunspot numbers. Similarly, both geomagnetic activity and global surface temperature anomaly can be linked to cyclic changes in the solar activity. The interlinked variations in the solar magnetic activity and in the solar irradiance cause effects that can be observed both in the Earth's biosphere and in the electromagnetic environment. The long-term data sets suggest that the increase in geomagnetic activity and surface temperatures are related (at least partially) to longer-term solar variations, which probably include an increasing trend superposed with a cyclic behavior with a period of about 90 years.     

Printed circuit board diagnosis using artificial neural networksand circuit magnetic fields

Testing of electronic systems using conventional testing methods has become more difficult and costly as these systems have become more complex and compact. Conventional testing methods and systems often require lengthy analysis to define testing strategies. These test systems may require lengthy test periods, complex stimulus and measurement instrumentation as well as complicated fixturing. The results are often ambiguous and require further interpretation. This paper presents an exploration of a “non-intrusive” test method based on interpreting changes in the magnetic field close to a Printed Circuit Board (PCB). Currents moving between devices on the PCB produce these magnetic fields. Changes of the PCB operational status due to faults cause changes in the associated magnetic field pattern that can be interpreted by Artificial Neural Networks (ANNs) for fault identification. An apparatus to collect magnetic field measurements is described along with some problems of collecting data. Typical magnetic field patterns for “known-good” and faulted PCBs are presented. Possible extensions of the method are discussed. This paper resulted from internally funded work at Southwest Research Institute (SwRI) concerning non-intrusive diagnostic techniques     

Composition and physical properties of starch in microgravity-grown plants.

The effect of spaceflight on starch development in soybean (Glycine max L., BRIC-03) and potato (Solanum tuberosum, Astroculture-05) was compared with ground controls by biophysical and biochemical measurements. Starch grains from plants from both flights were on average 20-50% smaller in diameter than ground controls. The ratio delta X/delta rho (delta X --difference of magnetic susceptibilities, delta rho--difference of densities between starch and water) of starch grains was ca. 15% and 4% higher for space-grown soybean cotyledons and potato tubers, respectively, than in corresponding ground controls. Since the densities of particles were similar for all samples (1.36 to 1.38 g/cm3), the observed difference in delta X/delta rho was due to different magnetic susceptibilities and indicates modified composition of starch grains. In starch preparations from soybean cotyledons (BRIC-03) subjected to controlled enzymatic degradation with alpha-amylase for 24 hours, 77 +/- 6% of the starch from the flight cotyledons was degraded compared to 58 +/- 12% in ground controls. The amylose content in starch was also higher in space-grown tissues. The good correlation between the amylose content and delta X/delta rho suggests, that the magnetic susceptibility of starch grains is related to their amylose content. Since the seedlings from the BRIC-03 experiment showed elevated post-flight ethylene levels, material from another flight experiment (GENEX) which had normal levels of ethylene was examined and showed no difference to ground controls in size distribution, density, delta X/delta rho and amylose content. Therefore the role of ethylene appears to be more important for changes in starch metabolism than microgravity.     

Potential vascular damage from radiation in the space environment.

Cultured endothelial cells of blood vessels have a Do of 2 Gy for X-rays. A dose of 0.5 Gy of X-rays has an acute effect on vessel diameter. The vessels may show other acute effects such as change in permeability including a change in the blood brain barrier. Changes occurring from late effects of chronic exposure in vascular architecture include telangiectasia and decrease in vascular density. Changes in the perivascular connective tissue particularly collagen may play a role in these changes. After charged particle exposure of 15 and 30 Gy, radiation changes in the blood brain barrier and vascular changes are noted in the nervous system. These long term changes are recorded by PET, MRI, and CT imaging. Chronic exposure to alpha particles causes vascular damage in compact bone resulting in bone infarcts. Using tandem scanning confocal microscopy in-situ imaging of the capillaries and collagen of the papillary dermis provides a non-invasive method of serial recording of changes in irradiated microvasculature.     

Particle trajectories in seeds of Lactuca sativa and chromosome aberrations after exposure to cosmic heavy ions on Cosmos Biosatellites 8 and 9.

The potentially specific importance of the heavy ions of the galactic cosmic radiation for radiation protection in manned spaceflight continues to stimulate in situ, i.e., spaceflight experiments to investigate their radiobiological properties. Chromosome aberrations as an expression of a direct assault on the genome are of particular interest in view of cancerogenesis being the primary radiation risk for man in space. In such investigations the establishment of the geometrical correlation between heavy ions' trajectories and the location of radiation sensitive biological substructures is an essential task. The overall qualitative and quantitative precision achieved for the identification of particle trajectories in the order of approximately 10 micrometers as well as the contributing sources of uncertainties are discussed. We describe how this was achieved for seeds of Lactuca sativa as biological test organisms, whose location and orientation had to be derived from contact photographies displaying their outlines and those of the holder plates only. The incidence of chromosome aberrations in cells exposed during the COSMOS 1887 (Biosatellite 8) and the COSMOS 2044 (Biosatellite 9) mission was determined for seeds hit by cosmic heavy ions. In those seeds the incidence of both single and multiple chromosome aberrations was enhanced. The results of the Biosatellite 9 experiment, however, are confounded by spaceflight effects unrelated to the passage of heavy ions.     

Synthetic vision for enhancing poor visibility flight operations

Visibility is important for the pilot controlling an aircraft in flight conditions close to the ground, particularly when landing. Therefore, poor visibility yields a great restriction for aircraft operations. Restrictions exist for landing sites which are equipped with facilities providing a landing approach aid like ILS since a minimum is required for visibility. For landing sites providing no approach aids, restrictions are much more severe. This holds even if aircraft are equipped with modern instrumentation and navigation devices. The natural view of the pilot is dependent on various meteorological conditions like darkness, dust, fog, rain etc. The degradation in view caused by these conditions can be compensated for partially or even completely by technical means providing artificial vision cues. Such technical means may be based on radar or optical sensor information. Concepts which employ these techniques are known as “Synthetic Visual Systems” or “Enhanced Visual Systems,” . The present paper is concerned with computer generated vision as a further technique providing visual cues for the pilot. Computer generated vision may be used in combination with the aforementioned sensor based techniques. Thus, it is possible to compensate for limitations which sensor based visual systems have in providing sufficient visibility range or in generating a normal looking image. In addition, computer generated imagery has the potential providing additional information to the pilot for controlling the flight path or for warning purposes. This potential can yield improved and/or more information as compared with the natural view when looking out of the cockpit window