Induction of high grade astrocytoma (HGA) by protons: molecular mechanisms and RBE considerations.

Protons of a specific energy, 55 MeV, have been found to induce primary high grade astrocytomas (HGA) in the Rhesus monkey (Macaca mulatta). Brain tumors of this type were not induced by protons of other energies (32-2,300 MeV). Induction of HGA has been identified in human patients who have had radiation therapy to the head. We believe that the induction of HGA in the monkey is a consequence of dose distribution, not some unique "toxic" property of protons. Comparison of the human experience with the monkey data indicates the RBE for induction of brain tumors to be about one. It is unlikely that protons cause an unusual change in oncogenic expression, as compared to conventional electromagnetic radiation.     

Regolith X-Ray Imaging Spectrometer (REXIS) Aboard the OSIRIS-REx Asteroid Sample Return Mission

The Regolith X-ray Imaging Spectrometer (REXIS) is the student collaboration experiment proposed and built by an MIT-Harvard team, launched aboard NASA’s OSIRIS-REx asteroid sample return mission. REXIS complements the scientific investigations of other OSIRIS-REx instruments by determining the relative abundances of key elements present on the asteroid’s surface by measuring the X-ray fluorescence spectrum (stimulated by the natural solar X-ray flux) over the range of energies 0.5 to 7 keV. REXIS consists of two components: a main imaging spectrometer with a coded aperture mask and a separate solar X-ray monitor to account for the Sun’s variability. In addition to element abundance ratios (relative to Si) pinpointing the asteroid’s most likely meteorite association, REXIS also maps elemental abundance variability across the asteroid’s surface using the asteroid’s rotation as well as the spacecraft’s orbital motion. Image reconstruction at the highest resolution is facilitated by the coded aperture mask. Through this operation, REXIS will be the first application of X-ray coded aperture imaging to planetary surface mapping, making this student-built instrument a pathfinder toward future planetary exploration. To date, 60 students at the undergraduate and graduate levels have been involved with the REXIS project, with the hands-on experience translating to a dozen Master’s and Ph.D. theses and other student publications.     

Energy Spectrum of Galactic 10–100 MeV Protons in Quiet Sun Periods

The dynamics of the proton energy spectrum during the solar cycle is studied. The spectra were determined by 1–100 MeV particle fluxes measured by different instruments mounted aboard the Earth's IMP-8 satellite for more than one hundred quiet-time intervals in the period between 1974 and 1991. The galactic branch of the spectra (E_p > 10 MeV) constructed for every quiet interval was fitted by a power law function, J =CE. The theory predicts that in the 1–100 MeV energy range, where the adiabatic cooling of particles is dominant, = 1, while we have derived a double-peak distribution. The main maximum has the mean value = 1.35. The mean value of the second, much weaker maximum, is = 0.95. Within the main maximum, values are distributed in accordance with the Gaussian law with a standard deviation D/ = 0.12. The substantial difference of from unity requires the elaboration of a new model of modulation processes in the inner heliosphere. The values corresponding to the second maximum show that modulation processes correspond sometimes to theoretical conceptions. It is shown that correlates weakly with parameters A and describing the solar branch of the spectrum (J(E) = AE^–). At the same time, a more significant correlation is observed between and the solar activity index, R_z, the counting rate of the Deep River neutron monitor, and the energy value in the minimum of the energy spectrum flux, E_min.     

DIRECT NUMERICAL SIMULATIONS OF MULTIPHASE FLOWS

INTRODUCTIONMultiphase and multifluid flows are commonin many natural and technologically importantprocesses. Rain,spray combustion,spray paint-ing,and boiling heat transfer are just a few ex-amples.While it is the overall,integral charac-teristics of such flows that are of most interest,the global behavior is determined to a large de-gree by the evolution of the smallestscales in theflow.The combustion of sprays,for example,depends on the size and the number density ofthe drops.Generally…     

Dynamic dissipative compensators for multibody flexible spacestructures

The stability characteristics of dynamic dissipative compensators are investigated for multibody flexible space structures having nonlinear dynamics. The problem addressed is that of proving asymptotic stability of dynamic dissipative compensators. The stability proof uses the Lyapunov approach and exploits the inherent passivity of such systems. For such systems these compensators are shown to be robust to parametric uncertainties and unmodeled dynamics. The results are applicable to a large class of structures such as satellites with multiple payloads and space-based manipulators     

Full characterization of a compact 90Sr/90Y beta source for TID radiation testing

A new methodology for Total Ionizing Dose (TID) tests is proposed. It is based on the employment of an on-chip ⁹⁰Sr/⁹⁰Y beta source as alternative to standard methods such as ⁶⁰Co gamma rays and electrons from LINAC. The use of a compact beta source for TID tests has several advantages. In particular, the irradiation of devices with more than one radiation source results in a better representation of the complex space radiation environment composed of several types, energies and dose-rates. In addition, the use of an easy handling beta source allows the irradiation of electronic devices without any damage to other auxiliary circuit. In this work, ⁹⁰Sr/⁹⁰Y beta source dosimetry and related radiation field characteristics are discussed in depth.In order to validate the proposed source for TID tests, a rather complex device such as the “SPC56EL70L5” microcontroller from ST-Microelectronics was exposed to ⁹⁰Sr/⁹⁰Y beta rays. The results of this test were compared to that of a previous test of another sample from the same lot with a standard gamma ⁶⁰Co source. The electronic performances following the two irradiations have been found to be in excellent agreement, by demonstrating therefore the validity of the proposed beta source for TID tests.     

Variations of the solar acoustic high-degree mode frequencies over solar cycle 23

Using full-disk observations obtained with the Michelson Doppler Imager (MDI) on board the Solar and Heliospheric Observatory (SOHO) spacecraft, we present variations of the solar acoustic mode frequencies caused by the solar activity cycle. High-degree (100 < ? < 900) solar acoustic modes were analyzed using global helioseismology analysis techniques over most of solar cycle 23. We followed the methodology described in details in [Korzennik, S.G., Rabello-Soares, M.C., Schou, J. On the determination of Michelson Doppler Imager high-degree mode frequencies. ApJ 602, 481–515, 2004] to infer unbiased estimates of high-degree mode parameters ([see also Rabello-Soares, M.C., Korzennik, S.G., Schou, J. High-degree mode frequencies: changes with solar cycle. ESA SP-624, 2006]). We have removed most of the known instrumental and observational effects that affect specifically high-degree modes. We show that the high-degree changes are in good agreement with the medium-degree results, except for years when the instrument was highly defocused. We analyzed and discuss the effect of defocusing on high-degree estimation. Our results for high-degree modes confirm that the frequency shift scaled by the relative mode inertia is a function of frequency and it is independent of degree.