Induction of high grade astrocytoma (HGA) by protons: molecular mechanisms and RBE considerations.

Protons of a specific energy, 55 MeV, have been found to induce primary high grade astrocytomas (HGA) in the Rhesus monkey (Macaca mulatta). Brain tumors of this type were not induced by protons of other energies (32-2,300 MeV). Induction of HGA has been identified in human patients who have had radiation therapy to the head. We believe that the induction of HGA in the monkey is a consequence of dose distribution, not some unique "toxic" property of protons. Comparison of the human experience with the monkey data indicates the RBE for induction of brain tumors to be about one. It is unlikely that protons cause an unusual change in oncogenic expression, as compared to conventional electromagnetic radiation.     

Radiation risk of the crew members of the expeditions on the "MIR" station during the 22nd solar activity cycle.

The radiation risk at the end of the flight was calculated for the members of the main expeditions on the "Mir" station. It was based on the absorbed dose dynamics data measured by the board dosimeter. The radiation damage models created for standards of the radiation safety of the space flights were used in the calculations. The analysis of the obtained values of the risk and its dynamics for some cosmonauts are presented in the topic. The risk values delta P are close to the limited levels given by equation of delta P = 0.6 x 10 x T(-4), [this equation appears also as delta RHrad = 0.6 x 10(-4) x T later in the text] where T--is flight duration in months.     

A demonstration of the potential of Cryosat-2 to contribute to mesoscale observation

Cryosat-2 was designed for its primary scientific objectives, i.e. for cryosphere science. As far as oceanography is concerned, various mission design choices make it less accurate than missions designed to comply with ocean surface topography requirements such as Jason-2 or ENVISAT. Cryosat-2-specific errors are equivalent to more than 50% of the sea surface height variability over 40% of the oceans. Cryosat-2’s sampling pattern is also suboptimal for mesoscale observation because the satellite tracks from any consecutive period of 2 to 20 days (e.g. the most recent and most valuable data for near real time mesoscale observation) are aggregated in 500 km wide bands which are interleaved with 500 km wide observation gaps.     

Probing the first stars and black holes in the early Universe with the Dark Ages Radio Explorer (DARE)

A concept for a new space-based cosmology mission called the Dark Ages Radio Explorer (DARE) is presented in this paper. DARE’s science objectives include: (1) When did the first stars form? (2) When did the first accreting black holes form? (3) When did Reionization begin? (4) What surprises does the end of the Dark Ages hold (e.g., Dark Matter decay)? DARE will use the highly-redshifted hyperfine 21-cm transition from neutral hydrogen to track the formation of the first luminous objects by their impact on the intergalactic medium during the end of the Dark Ages and during Cosmic Dawn (redshifts z = 11–35). It will measure the sky-averaged spin temperature of neutral hydrogen at the unexplored epoch 80–420 million years after the Big Bang, providing the first evidence of the earliest stars and galaxies to illuminate the cosmos and testing our models of galaxy formation. DARE’s approach is to measure the expected spectral features in the sky-averaged, redshifted 21-cm signal over a radio bandpass of 40–120 MHz. DARE orbits the Moon for a mission lifetime of 3 years and takes data above the lunar farside, the only location in the inner solar system proven to be free of human-generated radio frequency interference and any significant ionosphere. The science instrument is composed of a low frequency radiometer, including electrically-short, tapered, bi-conical dipole antennas, a receiver, and a digital spectrometer. The smooth frequency response of the antennas and the differential spectral calibration approach using a Markov Chain Monte Carlo technique will be applied to detect the weak cosmic 21-cm signal in the presence of the intense solar system and Galactic foreground emissions.     

Seasonal-to-interannual variability of chlorophyll-a bloom timing associated with physical forcing in the Gulf of Cádiz

Seasonal-to-interannual variability of the winter-spring bloom in the Gulf of Cádiz, eastern North Atlantic, has been investigated using chlorophyll-a remote sensing (CHL). These data have been obtained from the GlobColour project; the temporal coverage extends from September 1997 to December 2010. In this study we develop a generic quantitative approach for describing the temporal variability in the shape of the winter-spring bloom within a region. Variability in both the timing and magnitude of the bloom in the basin has been evaluated as a function of physical properties in the water column such as Mixed Layer Depth (MLD, GODAS model), sea surface temperature (SST, from AVHRR radiometers), photosynthetically-active radiation (PAR, from ocean color data) and euphotic depth (Z_eu, from ocean color data). The analysis indicated that the timing, size and duration of the phytoplankton bloom in this area are largely controlled by both meteorological and oceanographic conditions at different scales; this means that it is likely to vary widely from one year to another.     

Satellite and ground detection of very dense smoke clouds produced on the islands of the Paraná river delta that affected a large region in Central Argentina

Intense fires were produced on the Paraná river delta islands, Argentina, during most part of 2008, by a combination of an exceptionally dry period and the farmers’ use of a fire land-cleaning technique. In April 2008, those fires significantly affected the nearby regions and their inhabitants, from Rosario city to Buenos Aires mega-city. In this work we present satellite as well as ground Aerosol Optical Depth (AOD) at 550 nm data obtained during the propagation of pollution clouds to the central zone of Argentina. The highest value (1.18) was registered at Buenos Aires by atmospheric remote sensing, using the satellite instrument MODIS/Terra on April 18th 2008 at 10:35 local time (= UT − 3 h). On the same day, ground air quality detectors also measured in this city the highest Total Suspended Particle (TSP) value of the month, 2.02 mg/m³. The AOD(550) daily variation at Rosario Astronomical Observatory, which is located near the Paraná riverside, was derived by combining solar ultraviolet erythemal irradiance data (measured with a YES biometre) with model calculations. On April 25th 2008, from 12:00 to 15:30 local time, a rather high and constant AOD(550) value was registered, with a mean value of (0.90 ± 0.21). Cities located on the side of the Rosario–Buenos Aires highway (San Nicolás, Baradero and San Pedro) were also affected, showing a mean AOD(550) between the Rosario and Buenos Aires values. The particulate matter was collected with gridded samplers placed on the Paraná river islands as well as at the Rosario Observatory. They were analysed with a Scanning Electron Microscope (SEM) and mainly showed a biological origin. Even if normally large particles travel small distances from the source, organic aerosol in the range of 40–100 μm and complex asymmetric structures were registered several kilometres away from the aerosol sources on the islands. Another event of intense UV index attenuation (98.6%) occurred on September 18th 2008, due to very dense smoke clouds that extended over the Rosario area for several hours. The clouds were driven away from the fires by East–northeast and East–southeast winds. The minimum value of this index measured around noon allows to derive a maximum AOD(550)_max = (3.65 ± 0.90) at 12:45 local time. Soot clouds extended over the Paraná river, transporting Burned Biomass Debris (BBD) that deposited on Rosario. In particular, burned leaves and small branches with dimensions of 1–20 cm were collected. The mean (BBD) particles deposited on the ground from 7:00 to 19:00 local time were (0.92 ± 0.20) BBD/(m² h).     

Full characterization of a compact 90Sr/90Y beta source for TID radiation testing

A new methodology for Total Ionizing Dose (TID) tests is proposed. It is based on the employment of an on-chip ⁹⁰Sr/⁹⁰Y beta source as alternative to standard methods such as ⁶⁰Co gamma rays and electrons from LINAC. The use of a compact beta source for TID tests has several advantages. In particular, the irradiation of devices with more than one radiation source results in a better representation of the complex space radiation environment composed of several types, energies and dose-rates. In addition, the use of an easy handling beta source allows the irradiation of electronic devices without any damage to other auxiliary circuit. In this work, ⁹⁰Sr/⁹⁰Y beta source dosimetry and related radiation field characteristics are discussed in depth.In order to validate the proposed source for TID tests, a rather complex device such as the “SPC56EL70L5” microcontroller from ST-Microelectronics was exposed to ⁹⁰Sr/⁹⁰Y beta rays. The results of this test were compared to that of a previous test of another sample from the same lot with a standard gamma ⁶⁰Co source. The electronic performances following the two irradiations have been found to be in excellent agreement, by demonstrating therefore the validity of the proposed beta source for TID tests.     

Relativistic electron fluxes and dose rate variations during April–May 2010 geomagnetic disturbances in the R3DR data on ISS

Space radiation has been monitored successfully using the Radiation Risks Radiometer-Dosimeter (R3D) installed at the ESA EXPOSE-R (R3DR) facility outside of the Russian Zvezda module of the International Space Station (ISS) between March 2009 and January 2011. R3DR is a Liulin type spectrometer–dosimeter with a single Si PIN detector 2 cm² of area and 0.3 mm thick. The R3DR instrument accumulated about 2 million measurements of the absorbed dose rate and flux of 10 s resolution. The total external and internal shielding before the detector of R3DR device is 0.41 g cm⁻². The calculated stopping energy of normally incident particles to the detector is 0.78 MeV for electrons and 15.8 MeV for protons. After the Coronal Mass Ejection (CME) at 09:54 UTC on 3 April 2010, a shock was observed at the ACE spacecraft at 0756 UTC on 5 April, which led to a sudden impulse on Earth at 08:26 UTC. Nevertheless, while the magnetic substorms on 5 and 6 of April were moderate; the second largest in history of GOES fluence of electrons with energy >2 MeV was measured. The R3DR data show a relatively small amount of relativistic electrons on 5 April. The maximum dose rate of 2323 μGy day⁻¹ was reached on 7 April; by 9 April, a dose of 6600 μGy was accumulated. By the end of the period on 7 May 2010 a total dose of 11,587 μGy was absorbed. Our data were compared with AE-8 MIN, CRESS and ESA-SEE1 models using SPENVIS and with similar observations on American, Japanese and Russian satellites.     

Modified energy cascade model adapted for a multicrop Lunar greenhouse prototype

Models are required to accurately predict mass and energy balances in a bioregenerative life support system. A modified energy cascade model was used to predict outputs of a multi-crop (tomatoes, potatoes, lettuce and strawberries) Lunar greenhouse prototype. The model performance was evaluated against measured data obtained from several system closure experiments. The model predictions corresponded well to those obtained from experimental measurements for the overall system closure test period (five months), especially for biomass produced (0.7% underestimated), water consumption (0.3% overestimated) and condensate production (0.5% overestimated). However, the model was less accurate when the results were compared with data obtained from a shorter experimental time period, with 31%, 48% and 51% error for biomass uptake, water consumption, and condensate production, respectively, which were obtained under more complex crop production patterns (e.g. tall tomato plants covering part of the lettuce production zones). These results, together with a model sensitivity analysis highlighted the necessity of periodic characterization of the environmental parameters (e.g. light levels, air leakage) in the Lunar greenhouse.