Induction of genomic instability after an acute whole-body exposure of mice to Fe ions

The purpose of this study was to evaluate dose–response relationships for the in vivo induction of micronuclei (MN) as a measure of both initial radiation damage and the induction of genomic instability. These measurements were made in mouse blood erythrocytes as a function of radiation dose, radiation quality, time after irradiation, and the genetic background of exposed individuals. Blood samples were collected from two strains of mouse (CBA/CaJ and C57BL/6J) at different times up to 3 months following a whole-body exposure to various doses of 1 GeV/amu ⁵⁶Fe ions (0, 0.1, 0.5 and 1.0 Gy, at the dose rate of a 1 Gy/min) or ¹³⁷Cs gamma rays (0, 0.5, 1.0 and 3.0 Gy, at the dose rate of 0.72 Gy/min). Blood-smear slides were stained with acridine orange (AO). The frequencies of MN were measured in mature normochromatic-erythrocytes (MN-NCEs) and in immature polychromatic-erythrocytes (MN-PCEs). Effects of both types of radiation on erythropoiesis were also evaluated. As a measure of cell progression delay, a dose-dependent decrease in numbers of PCEs was observed at day 2 post-exposure in both strains, regardless of radiation quality. Subsequently, the levels of PCEs increased in all exposed mice, reaching control levels (or higher) by day 7 post-exposure. Further, at day 2 after the exposure, there was no increase in the frequency of MN-PCEs in CBA/CaJ mice exposed to ⁵⁶Fe ions while the frequency of MN-PCEs elevated as a function of dose in the C57BL/6J mice. At day 4, there was no dose related increase in MN-NCEs in either strain of mouse exposed to ¹³⁷Cs gamma rays. Additionally, at the early sacrifice times (days 2 and 4), ⁵⁶Fe ions were slightly more effective (per unit dose) in inducing MN-NCEs than ¹³⁷Cs gamma rays in CBA/CaJ mice. However, there was no increase in the frequency of MN-NCEs at late times after an acute exposure to either type of radiation. In contrast, both types of radiation induced increased MN-PCEs frequencies in irradiated CBA/CaJ mice, but not C57BL/6J mice, at late times post-exposure. This finding indicates the potential induction of genomic instability in hematopoietic cells of CBA/CaJ mice by both types of radiation. The finding also demonstrates the influence of genetic background on radiation-induced genomic instability in vivo.     

Transport modeling of energetic electrons in the inner magnetosphere with synchrotron energy losses

The resulting L-distributions and energy spectra of energetic magnetospheric electrons obtained from numerical solution of the radiation belt transport equation with and without accounting for electron synchrotron energy losses are compared. It is demonstrated that synchrotron losses play an important role in formation of the space and energetic distributions of electrons in the inner magnetosphere.     

Study of cosmic rays and light flashes on board Space Station MIR: the SilEye experiment.

The SilEye experiment aims to study the cause and processes related to the anomalous Light Flashes (LF) perceived by astronauts in orbit and their relation with Cosmic Rays. These observations will be also useful in the study of the long duration manned space flight environment. Two PC-driven silicon detector telescopes have been built and placed aboard Space Station MIR. SilEye-1 was launched in 1995 and provided particles track and LF information; the data gathered indicate a linear dependence of FLF(Hz) ( 4 2) 10(3) 5.3 1.7 10(4) Fpart(Hz) if South Atlantic Anomaly fluxes are not included. Even though higher statistic is required, this is an indication that heavy ion interactions with the eye are the main LF cause. To improve quality and quantity of measurements, a second apparatus, SilEye-2, was placed on MIR in 1997, and started work from August 1998. This instrument provides energetic information, which allows nuclear identification in selected energy ranges; we present preliminary measurements of the radiation field inside MIR performed with SilEye-2 detector in June 1998.     

1994年2月21日行星际激波引起的磁暴

利用Imp-8,Geotail和Goes-6等卫星资料,研究了1994年2月21日0900UT到达地球磁层的行星际激波引起的磁暴期间,从太阳风向磁层传输能量的有关问题.结果指出:（1）南向行星际磁场（IMF）的长持续时间不是太阳风向磁层输能的必要条件.南北振荡的,较强IMF也能产生显著的能量传输;（2）行星际扰动磁场通过弓激波和磁层顶后扰动磁能增加,增幅将近5倍;（3）在磁层内扰动磁场的Bz分量在1×10-4Hz附近显著被吸收.这一低频扰动磁场可能是磁暴期间导致氧离子和质子等环电流粒子向内扩散并被加速的原因之一.     

Improved interpretation of solar wind ion measurements via high-resolution magnetic field data

The Wind   spacecraft’s Faraday cups (FC) continue to produce high-quality, in situ observations of thermal protons (i.e., ionized hydrogen) and α$\alpha$-particles (i.e., fully ionized helium) in the solar wind. By fitting a Wind/FC ion spectrum with a model velocity distribution function (VDF) for each particle species, values for density, bulk velocity, and temperature can be inferred. Incorporating measurements of the background magnetic field from the Wind Magnetic Field Investigation (MFI) allows perpendicular and parallel temperature components to be separated. Prior implementations of this analysis averaged the higher-cadence Wind/MFI measurements to match that of the Wind/FC ion spectra. However, this article summarizes recent and extensive revisions to the analysis software that, among other things, eliminate such averaging and thereby account for variations in the direction of the magnetic field over the time taken to measure the ions. A statistical comparison reveals that the old version consistently underestimates the temperature anisotropy of ion VDF’s: averaging over fluctuations in the magnetic field essentially blurs the perpendicular and parallel temperature components, which makes the plasma seem artificially more isotropic. The new version not only provides a more accurate dataset of ion parameters (which is well suited to the study of microkinetic phenomena), it also demonstrates a novel technique for jointly processing particle and field data. Such methods are crucial to heliophysics as wave-particle interactions are increasingly seen as playing an important role in the dynamics of the solar wind and similar space plasmas.     

Physical Calibrations of the FREND Instrument Installed Onboard TGO Martian Orbiter

Cosmic Research - The article presents results of ground calibrations of the FREND neutron telescope installed onboard the TGO spacecraft of the Russian-European ExoMars project. The main goal of...     

Spectral Characteristics of Self-Emission from Electric Thrusters with Closed Electron Drift in the Radio-Frequency Band for Various Propellants

Cosmic Research - We have considered procedure and results of the experimental study for spectral characteristics of self emission from laboratory models of electric thrusters with closed electron...     

SSA: Where does Europe stand now?

With the growing need for monitoring and awareness of all the objects in space (including debris) now recognized, the types of effort required towards this end are discussed, with the emphasis on European activities. A number of European documents acknowledging the problem are cited and initiatives to promote space situational awareness (SSA) are examined. While there is currently no provision in the EU budget beyond 2013 for protecting ground and space assets from space environmental threats, an encouraging degree of bilateral cooperation between member states suggests that an SSA capability is emerging in Europe.     

Program goals for the NASA/NOAA Earth Observation Program derived from a stakeholder value network analysis

The 2007 US National Research Council Decadal Survey for Earth Science and Applications from Space was the first consensus perspective produced by the US Earth Science community of the relative priorities among a sequence of 17 satellite missions over the course of the next decade. However, the Decadal Survey only captured the perspective of the science community, leading to questions about the inclusion of broader priorities from constituent communities and stakeholders. We present a stakeholder value network analysis for the NASA/NOAA Earth Observation Program. The analysis includes a rigorous articulation of the needs and objectives of 13 major stakeholders and a complete stakeholder value network with 190 individual “value flows” that capture the interactions between all the stakeholders. It produces a novel stakeholder map, graphically indicating the outputs most likely to create a lasting Earth Science program. The most important value loops and program outputs are used to derive a set of high-level program goals that suggest what NASA and NOAA should do, as well as how they should conduct business. The analysis concludes that international partnerships represent a strong potential partner for certain science missions with greater potential value delivery than currently-prioritized efforts with defense stakeholders and concludes that weather and land-use missions, in addition to climate missions, should be given highest priority; water, human health, and solid Earth missions should be given lower priority based on each science category's potential for delivering value to the entire stakeholder network.     

Some psychophysiological and behavioral aspects of adaptation to simulated autonomous Mission to Mars

“Mars-105” experiment was executed in March–July 2009 in Moscow, at the Institute for Bio-Medical Problems (IBMP) with participation of European Space Agency (ESA) to simulate some specific conditions of future piloted Mars mission. In the last 35 days of isolation, in order to simulate autonomous flight conditions, some serious restrictions were established for the crew resupply and communication with Mission Control (MC). The objective of the study was to investigate psychophysiological and behavioral aspects (communication) of adaptation during this period of “high autonomy”. We used computerized analysis of the crew written daily reports to calculate the frequencies of utilization of certain semantic units, expressing different psychological functions. To estimate the level of psycho-physiological stress, we measured the concentration of urinal cortisol once in two weeks. To investigate psycho-emotional state, we used the questionnaire SAN, estimating Mood, Activity and Health once in two weeks.During the simulation of autonomous flight, we found out the different tendencies of communicative behavior. One group of subjects demonstrated the tendency to “activation and self-government” under “high autonomy” conditions. The other subjects continued to use communicative strategy that we called “closing the communication channel”. “Active” communication strategy was accompanied by increasing in subjective scores of mood and activity. The subjects, whose communication strategy was attributed as “closing”, demonstrated the considerably lower subjective scores of mood and activity. Period of high autonomy causes specific changes in communication strategies of the isolated crew.