An Improved Algorithm for Adaptive Processing

The Widrow-Hoff least mean square (LMS) algorithm based on the method of steepest descent is conditionally stable. A modified algorithm is given which is unconditionally stable, capable of better performance when used in adaptive filter processing, and provides a more realistic means for simulating the Applebaum-Howells adaptive loop.     

Applied potential tomography shows differential changes in fluid content of leg tissue layers in microgravity.

Absence of hydrostatic forces in the human cardiocirculatory system normally leads to an overall body fluid deficit. It was hypothesized that this is mainly due to a loss of interstitial fluid. An experiment was performed on board the Russian MIR station. Cuffs were positioned around both thighs and inflated up to suprasystolic values. This maneuver took place just before and after immediately a lower body negative pressure session (LBNP). The redistribution of fluids underneath the cuffs was assessed by means of cross-sectional impedance tomography (Applied Potential Tomography, APT). A microgravity induced loss of interstitial fluid was measured in all layers of the observed cross-section. The APT-readings changed significantly (SD approximately +/- .9) from 3.0 at 1g to 1.7 at 0g for the outer layer and from 2.7 at 1g to 2.0 at 0g for the middle layer (expressed in arbitrary units). The LBNP maneuver was able to fill the interstitial space but only at levels higher than -15 mmHg LBNP. This suggests that the superficial tissues in the legs are as much affected as the deeper ones by changing g-conditions and LBNP can be used to counteract interstitial fluid loss in this area.     

The cataclysmic variable SS Cygni

In this work we will try to give the most general panorama, comparatively with the conciseness, on SS Cygni which is the brightest dwarf nova.The dwarf novae form a sub-class of the more vaste panorama of the Cataclysmic Variables (CVs). For this reason firstly we will describe in general the CVs and the current theories which attempt to describe their physical behaviour (Sections 2 and 3). The up-to-date observational properties of SS Cygni (Section 4) and a discussion on their explanation within the framework of theories (Section 5) will allow us to draw the conclusions (Section 6) and to argue the most convenient line of investigation (Section 7) both experimental and theoretical for a better understanding of the underlying physics of these systems.     

A novel way for the formation of alpha-amino acids and their derivatives in an aqueous medium.

In the course of a study of possible mechanism for chemical evolution in the primeval sea, we observed the formation of alpha-amino acids and N-acylamino acids from alpha-oxo acids and ammonia in an aqueous medium. Glyoxylic acid reacted with ammonia to form N-oxalylglycine, which gave glycine in a 5-39% yield after hydrolysis with 6N HCl. Similarly when glyoxylic acid was treated with methylamine it yielded N-oxalylsarcosine, which could be hydrolyzed to sarcosine with 17-25% overall yield upon hydrolysis. Pyruvic acid and ammonia reacted to give N-acetylalanine, which formed alanine in a 3-7% overall yield upon hydrolysis. The pH optima in these reactions were pH 3-4. These reactions were further extended to the formation of other amino acids. Glutamic acid, phenylalanine and serine were formed from alpha-ketoglutaric acid, phenylpyruvic acid and hydroxypyruvic acid, respectively, under similar conditions. N-Succinylglutamic acid was obtained as an intermediate for glutamic acid synthesis. Phenylacetylphenylalanineamide was also isolated as an intermediate for phenylalanine synthesis. Alanine, rather than aspartic acid, was produced from oxaloacetic acid. These reactions provide a novel route for the prebiotic synthesis of amino acids. A mechanism for the reactions is proposed.     

Proton flare and magnetic storm effect in the vicinity of the Earth.

We have developed a model and associated computational procedure for estimating energetic proton exposures during a major solar proton event that occur in combination with a large magnetic storm. Transmission functions for solar protons are computed using geomagnetic vertical cutoff data for quiescent and disturbed conditions. Predicted exposures in low altitude polar orbit are found to be orders of magnitude greater for severe magnetic storm conditions than are corresponding exposures in the absence of major disturbances. We examine the response scenario for the events of November 1960 as an example.     

Interstellar dust models

Interstellar dust models, previously constrained only from the extinction curve, have been radically changed with the arrival of IRAS observations of the dust infrared emission. An important component of interstellar dust is likely to be made of small particles that show a fluctuating temperature upon impinging single photons and which can produce large near and mid infrared excesses ubiquitously observed in the Galaxy and external galaxies. The analysis of COBE data should soon improve our understanding of dust infrared emissivity and particularly for big grains in the submillimeter domain. We will discuss the key observations (spectral features, broad-band colors, correlations with gas tracers…) which put the best constraints on any dust models and show that the next generation of IR/submm satellites (ISO, SIRTF…) should improve our knowledge of interstellar dust composition and the dust redistribution of the stellar energy inside galaxies.     

LET dependence of cell death, mutation induction and chromatin damage in human cells irradiated with accelerated carbon ions.

We investigated the LET dependence of cell death, mutation induction and chromatin break induction in human embryo (HE) cells irradiated by accelerated carbon-ion beams. The results showed that cell death, mutation induction and induction of non-rejoining chromatin breaks detected by the premature chromosome condensation (PCC) technique had the same LET dependence. Carbon ions of 110 to 124keV/micrometer were the most effective at all endpoints. However, the number of initially induced chromatin breaks was independent of LET. About 10 to 15 chromatin breaks per Gy per cell were induced in the LET range of 22 to 230 keV/micrometer. The deletion pattern of exons in the HPRT locus, analyzed by the polymerase chain reaction (PCR), was LET-specific. Almost all of the mutants induced by 124 keV/micrometer beams showed deletion of the entire gene, while all mutants induced by 230keV/micrometer carbon-ion beams showed no deletion. These results suggest that the difference in the density distribution of carbon-ion track and secondary electron with various LET is responsible for the LET dependency of biological effects.     

Certification of production-representative/productionsoftware-intensive systems for dedicated test and evaluation

Fundamental questions that arise in the certification of readiness for dedicated test and evaluation of software-intensive systems are addressed. They concern what comprises production-representative or production software, what are the software impacts on dedicated system operational test readiness, how software impacts should be considered in the certification process, and what are the retest/recertification requirements associated with software changes/modifications. A paradigm is proposed that answers these questions and outlines guidelines for implementing a solution to these issues. The paradigm is based on existing test and evaluation events and uses a combination of defense and commercial standards and definitions to propose criteria for software certification and retest or regression test     

Le silence éternel de ces espaces infinis?

During the last 40 years — the merest blip in world history — talk about Homo astronauticus has signalled a growing awareness that the passengers on planet Earth can, if they want, take off for other destinations. If the scale of past advances is a satisfactory measure of future possibilities, then the wish will be father of the achievement.