A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model.

When applied to the Colorado Plateau miner population, the two-stage clonal expansion (TSCE) model of radiation carcinogenesis predicts that radiation-induced promotion dominates radiation-induced initiation. Thus, according to the model, at least for alpha-particle radiation from inhaled radon daughters, lung cancer induction over long periods of protracted irradiation appears to be dominated by radiation-induced modification of the proliferation kinetics of already-initiated cells rather than by direct radiation-induced initiation (i.e., mutation) of normal cells. We explore the possible consequences of this result for radiation exposures to space travelers on long missions. Still unknown is the LET dependence of this effect. Speculations of the cause of this phenomenon include the suggestion that modification of cell kinetics is caused by a "bystander" effect, i.e., the traversal of normal cells by alpha particles, followed by the signaling of these cells to nearby initiated cells which then modify their proliferation kinetics.     

Mars Phobos and Deimos Survey (M-PADS) – A martian Moons orbiter and Phobos lander

We describe a Mars ‘Micro Mission’ for detailed study of the martian satellites Phobos and Deimos. The mission involves two ∼330 kg spacecraft equipped with solar electric propulsion to reach Mars orbit. The two spacecraft are stacked for launch: an orbiter for remote investigation of the moons and in situ studies of their environment in Mars orbit, and another carrying a lander for in situ measurements on the surface of Phobos (or alternatively Deimos). Phobos and Deimos remain only partially studied, and Deimos less well than Phobos. Mars has almost always been the primary mission objective, while the more dedicated Phobos project (1988–89) failed to realise its full potential. Many questions remain concerning the moons’ origins, evolution, physical nature and composition. Current missions, such as Mars Express, are extending our knowledge of Phobos in some areas but largely neglect Deimos. The objectives of M-PADS focus on: origins and evolution, interactions with Mars, volatiles and interiors, surface features, and differences. The consequent measurement requirements imply both landed and remote sensing payloads. M-PADS is expected to accommodate a 60 kg orbital payload and a 16 kg lander payload. M-PADS resulted from a BNSC-funded study carried out in 2003 to define candidate Mars Micro Mission concepts for ESA’s Aurora programme.     

Space storm measurements of the July 2005 solar extreme events from the low corona to the Earth

The Athens Neutron Monitor Data Processing (ANMODAP) Center recorded an unusual Forbush decrease with a sharp enhancement of cosmic ray intensity right after the main phase of the Forbush decrease on 16 July 2005, followed by a second decrease within less than 12 h. This exceptional event is neither a ground level enhancement nor a geomagnetic effect in cosmic rays. It rather appears as the effect of a special structure of interplanetary disturbances originating from a group of coronal mass ejections (CMEs) in the 13–14 July 2005 period. The initiation of the CMEs was accompanied by type IV radio bursts and intense solar flares (SFs) on the west solar limb (AR 786); this group of energetic phenomena appears under the label of Solar Extreme Events of July 2005. We study the characteristics of these events using combined data from Earth (the ARTEMIS IV radioheliograph, the Athens Neutron Monitor (ANMODAP)), space (WIND/WAVES) and data archives. We propose an interpretation of the unusual Forbush profile in terms of a magnetic structure and a succession of interplanetary shocks interacting with the magnetosphere.     

Microbial utilisation of natural organic wastes

The waste management strategy for the future should meet the benefits of humanity safety, respect principals of planet ecology, and compatibility with other habitability systems. For these purpose the waste management technologies, relevant to application of the biodegradation properties of bacteria are of great value. The biological treatment method is based upon the biodegradation of organic substances by various microorganisms. The advantage of the biodegradation waste management in general: it allows to diminish the volume of organic wastes, the biological hazard of the wastes is controlled, and this system may be compatible with the other systems. The objectives of our study were: to evaluate effectiveness of microbial biodegradation of non-pretreated substrate, to construct phneumoautomatic digester for organic wastes biodegradation, and to study microbial characteristics of active sludge samples used as inoculi in biodegradation experiment. The technology of vegetable wastes treatment was elaborated in IBMP and BMSTU. For this purpose the special unit was created where the degradation process is activated by enforced reinvention of portions of elaborated biogas into digester. This technology allows to save energy normally used for electromechanical agitation and to create optimal environment for anaerobic bacteria growth. The investigations were performed on waste simulator, which imitates physical and chemical content of food wastes calculated basing on the data on food wastes of moderate Russian city. The volume of created experimental sample of digester is 40 l. The basic system elements of device are digesters, gas receiver, remover of drops and valve monitoring and thermal control system. In our testing we used natural food wastes to measure basic parameters and time of biodegradation process. The diminution rate of organic gained 76% from initial mass taking part within 9 days of fermentation. The biogas production achieved 46 l per 1 kg of substrate. The microbial studies of biodegradation process revealed following peculiarities: (i) gradual quantitative increasing of Lactobacillus sp. (from 10(3) to 10(5) colony forming units (CFU) per ml), (ii) activation of Clostridia sp. (from 10(2) to 10(4)CFU/ml), (iii) elimination of aerobic conventional pathogens (Enterobacteriaceae sp., Protea sp., staphylococci). The obtained results allow to evaluate effectiveness of proposed technology and to determine the leading role of lactobacilli and clostridia in process of natural wastes biodegradation. Our further investigations shall further be concentrated on creation of artificial inoculi for launching of food wastes biodegradation. These inoculi will include active and adapted strains of clostridia and lactobacilli.     

A new method of determining the spectral index for protons in the energy range about 10<Superscript>13</Superscript> eV

We consider a relationship between the difference in spectral indices of the spectra of single hadrons and all hadrons (_sngl – _h) and the difference in the indices of the spectra of galactic cosmic ray (GCR) protons and nuclei. It is demonstrated that at the mountain level the ratio (_p – _Z)/(_sngl – _h) is always larger than unity, if (_sngl – _h) > 0.1. From the experimental value _sngl – _h = 0.4 ± 0.05 we derive that, in the vicinity of E = 10 TeV, _p – _Z 0.49 ± 0.06 , i.e., _p 3.09 ± 0.06.__________Translated from Kosmicheskie Issledovaniya, Vol. 43, No. 2, 2005, pp. 83–87.Original Russian Text Copyright © 2005 by Grigorov, Tolstaya.     

In situ measurements to determine if Phobos is layered

The complex system of linear features on Phobos—the inner moon of Mars—found by the Viking Orbiters in 1976, can be classified morphologically into three types according to their appearance as well as their geometrical distribution on the surface. One kind of grooves appears to form arcs of small circles normal to the Phobos-Mars direction. We propose that these grooves are the surface manifestation of layering within Phobos[4–6] which could have been formed when Phobos was a part of a much larger and geologically active parent planet.Here we suggest some measurements to observe whether Phobos has a layered structure or not. The suggestion contains remote sensing measurements (particularly determination of the magnetic field by magnetometer and by electron reflection method) by a spacecraft orbiting around Mars as well as surface measurements (active seismic reflection experiment) by a landing module on Phobos.     

A parametric study of space transfer/upper propulsion stages

For Space Transportation System (i.e. Space Shuttle) launched satellites destined for a Geosynchronous Earth Orbit (GEO), there is a need for cost-effective, versatile propulsion systems to provide the perigee burn, i.e. to boost the satellite from Low Earth Orbit (LEO) to Geosynchronous Transfer Orbit (GTO). Surveys of commercial spacecraft activities and future GEO satellite requirements indicate that a spacecraft propulsion system that will provide the perigee burn for a broad range of future commercial satellites would have an excellent market potential.Parametric studies to investigate and define attractive perigee-burn upper propulsion systems (i.e. an Upper Propulsion Stage, or a UPS) are presented. The feasibility and payload capacilities that could be provided by a UPS assembled from essentially off-the-shelf components and subsystems, and the benefits that could be achieved by using major subsystems specifically tailored for the application are presented. The results indicate that attractive UPS configurations can be defined using either off-the-shelf or optimized major subsystems.     

Study of radiation conditions onboard the International space station by means of the Liulin-5 dosimeter

For estimating radiation risk in space flights it is necessary to determine radiation dose obtained by critical organs of a human body. For this purpose the experiments with human body models are carried out onboard spacecraft. These models represent phantoms equipped with passive and active radiation detectors which measure dose distributions at places of location of critical organs. The dosimetric Liulin-5 telescope is manufactured with using three silicon detectors for studying radiation conditions in the spherical tissue-equivalent phantom on the Russian segment of the International space station (ISS). The purpose of the experiment with Liulin-5 instrument is to study dynamics of the dose rate and particle flux in the phantom, as well as variations of radiation conditions on the ISS over long time intervals depending on a phase of the solar activity cycle, orbital parameters, and presence of solar energetic particles. The Liulin-5 dosimeter measures simultaneously the dose rate and fluxes of charged particles at three depths in the radial channel of the phantom, as well as the linear energy transfer. The paper presents the results of measurements of dose rate and particle fluxes caused by various radiation field components on the ISS during the period from June 2007 till December 2009.