Heavy ion action on yeast cells: inhibition of ribosomal-RNA synthesis, loss of colony forming ability and induction of mutants.

The action of heavy ions (Ar to U) accelerated to specific energies up to about 10 MeV/u (u=atomic mass unit) on different functions of yeast cells was studied. Ribosomal-RNA synthesis is inhibited according to a single-hit mechanism. Inactivation cross-sections were linearly related to the ratio of the squares of the effective charge Z* and the velocity of the ions. It is concluded from the analysis that the range of the most energetic delta-electrons is larger than previously assumed. There is no such dependence for survival and induction of mutants. In both cases cross-sections increase with the ion's specific-energy indicating an important contribution of long-range delta-electrons. The analysis shows that diploid yeast is not killed by a single-hit mechanism even by very heavy ions if the track width is too small. The relative importance of the penumbral region is even more pronounced with the more sensitive strains.     

The Resolution Performance of Range Estimators

The theoretical basis and methods of implementation of a moment algorithm for the range separation estimation of two closely spaced point targets are presented. Moment estimation and noise filtering techniques introduced here result in a considerable improvement over Baum's algorithm. The error bounds are established and it is shown that the spectral moment estimator exhibits optimum (zero bias, minimum variance) performance when the target separation normalized to the standard deviation of the Gaussian pulse is 2?1.5. Monte Carlo simulation is performed to verify the approximations made and to demonstrate the feasibility of the working models.     

Informational need of emotional stress.

According to the informational theory of emotions, emotions in humans depend on the power of some need (motivation) and the estimation by the subject of the probability (possibility) of the need satisfaction (the goal achievement). Low probability of need satisfaction leads to negative emotions, actively minimized by the subject. Increased probability of satisfaction, as compared to earlier forecast, generates positive emotions, which the subject tries to maximize, i.e. to enhance, to prolong, to repeat. The informational theory of emotions encompasses their reflective function, the laws of their appearance, the regulatory significance of emotions, and their role in organization of behavior. The level of emotional stress influences the operator's performance. A decrease in the emotional tonus leads to drowsiness, lack of vigilance, missing of significant signals and to slower reactions. An extremely high stress level disorganizes the activity, complicates it with a trend toward incorrect actions and reactions to insignificant signals (false alarms). The neurophysiological mechanisms of the influence of emotions on perceptual activity and operator performance as well as the significance of individuality are discussed.     

Dissipation of temperature perturbations in the middle atmosphere

It is often observed that the stratospheric and mesospheric temperature structure undergoes transient disturbances from its averaged steady-state behavior. The causes may be traceable to gravity waves, planetary waves, solar proton and relativistic electron precipitation, etc. We examine the theoretical time behavior of the atmospheric temperature following the cessation of such heating phenomena as it relaxes toward its quiescent steady-state value. We also study the time-dependent response during a model stratospheric-warming/mesospheric-cooling event. In particular, we investigate the roles of eddy heat conduction, non-LTE cooling in the 15μm CO₂ band, and an ambient vertical wind, and their relative importance as they depend upon altitude and time, in modifying temperature changes in this region.     

Comments on `Detector relative efficiencies in the presence ofLaplace noise' by M.I. Dadi and J.R. Marks II

In the above-titled paper (see ibid., vol.AES-23, p.568-82, July 1987) M.I. Dadi and J.R. Marks II studied the relative efficiencies of the Neyman-Pearson optimal detector with respect to the linear and sign detectors, for the detection of a constant signal in additive Laplace noise. By applying the central limit theorem, they derived expressions for three types of asymptotic relative efficiencies (AREs). However, as noted in the above paper, the Gaussian approximation to the sign detector fails to yield the correct asymptotic efficiency. The commenter derives the correct ARE of the optimal detector with respect to the sign detector for the Laplace noise     

Comet nucleus sample return: Plans and capabilities

ROSETTA — the Comet Nucleus Sample Return mission — is one of the four Cornerstone missions to which ESA has committed itself in its approved Long-Term Programme Horizon 2000. The mission is currently being studied in collaboration with NASA. The comet-nucleus samples that ROSETTA is to provide will allow us to study some of the most primitive material in the solar system and the physical and chemical processes that marked the beginning of the system 4.6 billion years ago. For ESA, ROSETTA is a new type of mission: one which will return a sample at cryogenic temperature, and where as much effort has to be spent on preparing the laboratory analysis on-ground as has to be invested in preparing the space segment with the sample acquisition and in situ documentation. As part of the preparation for this mission, ESA is now starting to consider Planetary Protection issues.     

Energy and charge localization in irradiated DNA.

The relation between the site of energy deposition and the site of its biological action is an important question in radiobiology. Even at 77 degrees K, evidence is clear that these two sites must be separated since energy deposition is random but specific products are formed. Several processes that may contribute to this separation are: 1) hole migration and stabilization through deprotonation to give neutral oxidation product radicals; 2) electron trapping and transfer to form specific radical anions, possibly followed by protonation to give neutral reduction product radicals; and 3) recombination of spatially separated charges or radicals. These microscopic processes will be reviewed critically in an analysis using electron paramagnetic resonance spectroscopy (EPR) evidence for and against long-range transfer of energy and/or charge in frozen, hydrated DNA.     

A new system identification technique for harmonic decomposition

An extended and unifying system identification technique is presented for a class of systems that include all main signal models that arise in the harmonic decomposition problem. This technique unifies and extends the previously developed system identification techniques which are improvements on the Pisarenko harmonic decomposition (or, its spatial dual, MUSIC) as they arise in arrays of sensors. The advantages of the technique and some of its specializations include having no assumptions of stationarity on the stochastic processes involved. Another contribution of this technique is that it can also be used without any resort to probability theoretic concepts, thus bypassing the approximation of autocorrelations via time averages, yielding the system parameters exactly. This technique can be utilized to determine the dominant modes of vibrations of flexible structures as well. An analogy is established between arrays of sensors for target signal returns and those that can be used for vibrations in flexible structures. This enables the results developed for each one of these problems to be applied to the other     

Global communication using a constellation of low Earth meridianorbits

The concept of meridian orbits is briefly reviewed. It is shown that, if a satellite in the meridian orbit makes an odd number (>1) of revolutions per day, then the satellite passes over the same set of meridians twice a day. Satellites in such orbits pass over the same portion of the sky twice a day and every day. This enables a user to adopt a programmed mode of tracking, thereby avoiding a computational facility for orbit prediction, look angle generation, and auto tracking. A constellation of 38 or more satellites placed in a 1200-km altitude circular orbit is favorable for global communications due to various factors. It is shown that appropriate phasing in right ascension of the ascending node and mean anomaly results in a constellation wherein each satellite appears over the user's horizon one satellite after another. Visibility and coverage plots are provided to verify the continuous coverage     

Direct integration methods in dynamic problems of structural mechanics

A method of direct integration with respect to time is proposed to solve dynamic problems of structural mechanics and comparison with the well-known methods is presented.