Analysis of an adaptive algorithm for unbiased multipath time delay estimation

The multipath equalization time delay estimator (METDE) provides an adaptive approach for estimating the difference in arrival times of a signal received at spatially separated sensors as well as the multipath channel characteristics. However, the parameter estimates of the METDE are biased in the presence of noise. The METDE algorithm is improved for unbiased parameter estimation via minimizing a modified cost function. Convergence behaviors and variances of the system variables of the amended method are derived. Computer simulations are included to corroborate the theoretical analysis and to evaluate the adaptive multipath delay estimation performance of the proposed algorithm.     

Further comments on “Optimal sensor selection strategy fordiscrete-time estimators” [and reply]

The fundamental TPBVP usually underlying true “optimal sensor selection strategy” is revisited to obtain practical real-time mechanizations as a solution to an exclusively initial value problem     

How Operational Oceanography Can Benefit from Dynamic Topography Estimates as Derived from Altimetry and Improved Geoid

With a precise geoid, GOCE will allow an estimation of absolute dynamic topography from altimetry. The projected benefits to operational oceanography and its applications are analyzed herein. After a brief overview of operational oceanography, we explain how the new geoids will be used in the future to improve real time altimeter products and to better constrain modelling and data assimilation systems. A significant impact is expected both for mesoscale (e.g. better estimations and forecasts of currents for pollution monitoring, marine safety, offshore industry) and climate (better initialization of coupled ocean/atmosphere models) applications. This revised version was published online in August 2006 with corrections to the Cover Date.     

Spaceflight and clinorotation cause cytoskeleton and mitochondria changes and increases in apoptosis in cultured cells.

The cytoskeleton is a complex network of fibers that is sensitive to environmental factors including microgravity and altered gravitational forces. Cellular functions such as transport of cell organelles depend on cytoskeletal integrity; regulation of cytoskeletal activity plays a role in cell maintenance, cell division, and apoptosis. Here we report cytoskeletal and mitochondria alterations in cultured human lymphocyte (Jurkat) cells after exposure to spaceflight and in insect cells of Drosophila melanogaster (Schneider S-1) after exposure to conditions created by clinostat rotation. Jurkat cells were flown on the space shuttle in Biorack cassettes while Schneider S-1 cells were exposed to altered gravity forces as produced by clinostat rotation. The effects of both treatments were similar in the different cell types. Fifty percent of cells displayed effects on the microtubule network in both cell lines. Under these experimental conditions mitochondria clustering and morphological alterations of mitochondrial cristae was observed to various degrees after 4 and 48 hours of culture. Jurkat cells underwent cell divisions during exposure to spaceflight but a large number of apoptotic cells was also observed. Similar results were obtained in Schneider S-1 cells cultured under clinostat rotation. Both cell lines displayed mitochondria abnormalities and mitochondria clustering toward one side of the cells which is interpreted to be the result of microtubule disruption and failure of mitochondria transport along microtubules. The number of mitochondria was increased in cells exposed to altered gravity while cristae morphology was severely affected indicating altered mitochondria function. These results show that spaceflight as well as altered gravity produced by clinostat rotation affects microtubule and mitochondria organization and results in increases in apoptosis. Grant numbers: NAG 10-0224, NAG2-985.