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51.
Shane A.J. Lloyd Eric R. Bandstra Neil D. Travis Gregory A. Nelson J. Daniel Bourland Michael J. Pecaut Daila S. Gridley Jeffrey S. Willey Ted A. Bateman 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2008
Extended exposure to microgravity conditions results in significant bone loss. Coupled with radiation exposure, this phenomenon may place astronauts at a greater risk for mission-critical fractures. In a previous study, we identified a profound and prolonged loss of trabecular bone (29–39%) in mice following exposure to an acute, 2 Gy dose of radiation simulating both solar and cosmic sources. However, because skeletal strength depends on trabecular and cortical bone, accurate assessment of strength requires analysis of both bone compartments. The objective of the present study was to examine various properties of cortical bone in mice following exposure to multiple types of spaceflight-relevant radiation. Nine-week old, female C57BL/6 mice were sacrificed 110 days after exposure to a single, whole body, 2 Gy dose of gamma, proton, carbon, or iron radiation. Femora were evaluated with biomechanical testing, microcomputed tomography, quantitative histomorphometry, percent mineral content, and micro-hardness analysis. Compared to non-irradiated controls, there were significant differences compared to carbon or iron radiation for only fracture force, medullary area and mineral content. A greater differential effect based on linear energy transfer (LET) level may be present: high-LET (carbon or iron) particle irradiation was associated with a decline in structural properties (maximum force, fracture force, medullary area, and cortical porosity) and mineral composition compared to low-LET radiation (gamma and proton). Bone loss following irradiation appears to be largely specific to trabecular bone and may indicate unique biological microenvironments and microdosimetry conditions. However, the limited time points examined and non-haversian skeletal structure of the mice employed highlight the need for further investigation. 相似文献
52.
Aubrey AD Chalmers JH Bada JL Grunthaner FJ Amashukeli X Willis P Skelley AM Mathies RA Quinn RC Zent AP Ehrenfreund P Amundson R Glavin DP Botta O Barron L Blaney DL Clark BC Coleman M Hofmann BA Josset JL Rettberg P Ride S Robert F Sephton MA Yen A 《Astrobiology》2008,8(3):583-595
The Urey organic and oxidant detector consists of a suite of instruments designed to search for several classes of organic molecules in the martian regolith and ascertain whether these compounds were produced by biotic or abiotic processes using chirality measurements. These experiments will also determine the chemical stability of organic molecules within the host regolith based on the presence and chemical reactivity of surface and atmospheric oxidants. Urey has been selected for the Pasteur payload on the European Space Agency's (ESA's) upcoming 2013 ExoMars rover mission. The diverse and effective capabilities of Urey make it an integral part of the payload and will help to achieve a large portion of the mission's primary scientific objective: "to search for signs of past and present life on Mars." This instrument is named in honor of Harold Urey for his seminal contributions to the fields of cosmochemistry and the origin of life. 相似文献
53.
Hyung-Chul Lim Daniel Kucharski Simon Kim Chul-Sung Choi Ki-Pyoung Sung Jong-Uk Park Mansoo Choi Eunseo Park Sung-Yeol Yu Byoungsoo Kim 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2019,63(3):1122-1132
The imaging flash lidar has been considered as a promising sensor for the future space missions such as autonomous safe landing, spacecraft rendezvous and docking due to its ability to provide a full 3D scene with a single or multiple laser pulses. The linear-mode flash lidar has been developed and demonstrated for an autonomous safe landing on the Moon in order to provide an accurate distance measurement to the landing site and its 3D image. Yet, the Geiger-mode flash lidar has also been recognized as an emerging technology for the space missions because it is highly sensitive even to a single photon and provides the very accurate timing of photon arrival. In this study, the performance of the Geiger-mode flash lidar is simulated in the approach phase and evaluated for the autonomous landing on the Moon. Furthermore, a new statistical signal processing algorithm is proposed to remove the noise counts in order to obtain the 3D image from a sequence of laser pulses in the situation of the fast moving spacecraft. The algorithm is shown to be effective for the autonomous landing due to its ability to remove noise events under the condition of low signal-to-noise ratio and improve ranging accuracy. 相似文献
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Daniel Gómez Luis N. Martín Pablo Dmitruk 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2013
Because of its proximity, our Sun provides a unique opportunity to perform high resolution observations of its outer layers throughout the whole electromagnetic spectrum. We can also theoretically model most of the fascinating physical phenomena taking place on the Sun, as well as their impact on the solar system. 相似文献
56.
Validity and Sensitivity of a Brief Psychomotor Vigilance Test (PVT-B) to Total and Partial Sleep Deprivation 总被引:2,自引:0,他引:2
The Psychomotor Vigilance Test (PVT) objectively assesses fatigue-related changes in alertness associated with sleep loss, extended wakefulness, circadian misalignment, and time on task. The standard 10-min PVT is often considered impractical in applied contexts. To address this limitation, we developed a modified brief 3-min version of the PVT (PVT-B). The PVT-B was validated in controlled laboratory studies with 74 healthy subjects (34 female, aged 22-45 years) that participated either in a total sleep deprivation (TSD) study involving 33 hours awake (N=31 subjects) or in a partial sleep deprivation (PSD) protocol involving 5 consecutive nights of 4 hours time in bed (N=43 subjects). PVT and PVT-B were performed regularly during wakefulness. Effect sizes of 5 key PVT outcomes were larger for TSD than PSD and larger for PVT than for PVT-B for all outcomes. Effect size was largest for response speed (reciprocal response time) for both the PVT-B and the PVT in both TSD and PSD. According to Cohen's criteria, effect sizes for the PVT-B were still large (TSD) or medium to large (PSD, except for fastest 10% RT). Compared to the 70% decrease in test duration the 22.7% (range 6.9%-67.8%) average decrease in effect size was deemed an acceptable trade-off between duration and sensitivity. Overall, PVT-B performance had faster response times, more false starts and fewer lapses than PVT performance (all p<0.01). After reducing the lapse threshold from 500 ms to 355 ms for PVT-B, mixed model ANOVAs indicated no differential sensitivity to sleep loss between PVT-B and PVT for all outcome variables (all P>0.15) but the fastest 10% response times during PSD (P<0.001), and effect sizes increased from 1.38 to 1.49 (TSD) and 0.65 to 0.76 (PSD), respectively. In conclusion, PVT-B tracked standard 10-min PVT performance throughout both TSD and PSD, and yielded medium to large effect sizes. PVT-B may be a useful tool for assessing behavioral alertness in settings where the duration of the 10-min PVT is considered impractical, although further validation in applied settings is needed. 相似文献
57.
Gernot E. Groemer Michael Storrie-Lombardi Birgit Sattler Oliver Hauser Klaus Bickert Eva Hauth Stefan Hauth Ulrich Luger Daniel Schildhammer Daniel Foeger Jan Klauck 《Acta Astronautica》2011,68(1-2):218-225
As part of the “PolAres” research programme, we are investigating techniques to detect and reduce forward contamination of the Mars regolith during human exploration. We report here on the development of a spacesuit simulator-prototype dubbed “Aouda.X,” document the inability of current technology to produce a static charge sufficient to minimize dust transport on the suit, and present preliminary results employing laser induced fluorescence emission (L.I.F.E.) techniques to monitor fluorescent microspherules as biological contamination proxies. 相似文献
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60.
Daniel W. Swift 《Space Science Reviews》2001,95(1-2):489-500
The visual aurora takes on a variety of forms. Aurora has a tendency to appear first as very thin, highly structured forms. Over time, these tend to diffuse creating much thicker forms. It is suggested that the extreme variety of auroral forms can be understood in terms of one acceleration mechanism to produce a narrow, field-aligned beam and another process that scatters electrons into trapped orbits. The scattering is due to beam- plasma interactions that generate waves on the upper-hybrid resonance curve. These waves are effective in scattering electrons from parallel to perpendicular directions. The diffuse forms are therefore caused by precipitation of quasi-trapped electrons that have drifted from the field lines on which they were accelerated. Electrons scattered into trapped orbits may also constitute the seed population for the electron radiation belts. It is also suggested that the electron beams are accelerated by inertial Alfven waves that propagate current filaments from the turbulent region in the near-Earth plasma sheet to the auroral zone ionosphere. Electrons can be accelerated by becoming trapped in inertial Alfven waves whose phase velocity increases as they propagate toward the Earth. Specific numerical simulations that could give substance to these suggestions are proposed. 相似文献