Application potential of SPOT imagery for topographic mapping

The high resolution and good geometric configuration possible with SPOT gives a high potential for the production of 1:100 000 topographic maps. Studies at University College London have investigated this potential with the aid of a simple instrument which will introduce the necessary corrections to level 1b photographic images and orthophotographs and allow stereoscopic viewing of SPOT images and the ability to compile a line map. Accuracy has been investigated by computing ground co-ordinates from image co-ordinates and pixel positions. The methods used and results obtained in this work are described.Work is now going on to investigate the use of digital image processors in the mapping procedures and the use of analytical plotting instruments, and comments on this work and on future developments are made.     

Tissue responses to low protracted doses of high LET radiations or photons: early and late damage relevant to radio-protective countermeasures.

Early and late murine tissue responses to single or fractionated low doses of heavy charged particles, fission-spectrum neutrons or gamma rays are considered. Damage to the hematopoietic system is emphasized, but results on acute lethality, host response to challenge with transplanted leukemia cells and life-shortening are presented. Low dose rates per fraction were used in some neutron experiments. Split-dose lethality studies (LD 50/30) with fission neutrons indicated greater accumulation of injury during a 9 fraction course (over 17 days) than was the case for gamma-radiation. When total doses of 96 or 247 cGy of neutrons or gamma rays were given as a single dose or in 9 fractions, a significant sparing effect on femur CFU-S depression was observed for both radiation qualities during the first 11 days, but there was not an earlier return to normal with dose fractionation. During the 9 fraction sequence, a significant sparing effect of low dose rate on CFU-S depression was observed in both neutron and gamma-irradiated mice. CFU-S content at the end of the fractionation sequence did not correlate with measured LD 50/30. Sustained depression of femur and spleen CFU-S and a significant thrombocytopenia were observed when a total neutron dose of 240 cGy was given in 72 fractions over 24 weeks at low dose rates. The temporal aspects of CFU-S repopulation were different after a single versus fractionated neutron doses. The sustained reduction in the size of the CFU-S population was accompanied by an increase in the fraction in DNA synthesis. The proliferation characteristics and effects of age were different for radial CFU-S population closely associated with bone, compared with the axial population that can be readily aspirated from the femur. In aged irradiated animals, the CFU-S proliferation/redistribution response to typhoid vaccine showed both an age and radiation effect. After high single doses of neutrons or gamma rays, a significant age- and radiation-related deficiency in host defense mechanisms was detected by a shorter mean survival time following challenge with transplantable leukemia cells. Comparison of dose-response curves for life shortening after irradiation with fission-spectrum neutrons or high energy silicon particles indicated high initial slopes for both radiation qualities at low doses, but for higher doses of silicon, the effect per Gy decreased to a value similar to that for gamma rays. The two component life-shortening curve for silicon particles has implications for the potential efficacy of radioprotectants. Recent studies on protection against early and late effects by aminothiols, prostaglandins, and other compounds are discussed.     

The role of repair in the survival of mammalian cells from heavy ion irradiation: approximation to the ideal case of target theory.

Theories of cellular radiation sensitivity that preclude a significant role for cellular repair processes in the final biological expression of cellular damage induced by ionizing radiation are unsound. Experiments are discussed here in which the cell-cycle dependency of the repair deficiency of the S/S variant, of the L5178Y murine leukemic lymphoblast was examined by treatment with the heavy ions, 20Ne, 28Si, 40Ar, 56Fe and 93Nb. Evidence from those studies, which will be described in detail elsewhere, provide support for the notion that as the linear energy transfer (LET infinity) of the incident radiation increases the ability of the S/S cell to repair radiation damage decreases until effectively it is eliminated around 500 keV/micrometer. In the region of the latter LET infinity value, the behavior of the S/S cell approximates the ideal case of target theory where post-irradiation metabolism (repair) does not influence cell survival. The expression of this phenomenon among different cell types and tissues will depend upon the actual repair systems involved and other considerations.     

Fiber-optic gyros and quartz accelerometers for motion control

In article the opportunity of use strapdown inertial navigation system (SINS) on the base of fiber-optic gyroscopes and quartz accelerometers corrected from star sensors and satellite navigation equipment (SNE) for perspective interplanetary spacecrafts motion control on phases of interplanetary trajectory insertion, trajectory correction, and braking during transition to Mars orbit is investigated. Results of onboard control complex accuracy characteristics estimation are presented at the given dynamic spacecraft scheme which is taking into account the liquid oscillations in tanks and structure elements elasticity. At modelling the errors of measuring devices installation, errors of SINS initial alignment and instrumental errors of SINS sensitive elements, variation of control engines parameters were taken into account. The structure of the developed complex of imitation modelling of interplanetary spacecraft controlled motion is resulted. Estimations of active flight legs realization accuracy were received by a method of statistical modelling of spacecraft controlled motion     

Heat balance of the ionosphere: Implications for the international reference ionosphere

Theoretical considerations can be helpful tools in modelling ionospheric parameters in regions and for times where not enough experimental data are available. Our study asks whether results of heat balance calculations should be introduced to supplement the data base for the International Reference Ionosphere (IRI). We discuss the present status of our theoretical understanding and examine the influence of the following unresolved or neglected terms: (1) electron heating rate, (2) electron cooling by fine structure excitation of atomic oxygen, and (3) height-dependent Coulomb Logarithm. The ambiguity introduced by (1)–(3) leads up to 30% uncertainty in the electron temperature of the lower thermosphere. The electron temperature in the upper ionosphere is largely determined by heat conduction from above and depends critically on the conditions assumed at the boundary between ionosphere and plasmasphere.     

SPOT-2 and TOPEX/Poseidon precise orbit determination from DORIS doppler tracking

The French earth observation satellite SPOT-2 has served as a testbed for precise orbit determination from DORIS doppler tracking in anticipation of the TOPEX/Poseidon mission. Using the most up-to-data gravity field model, JGM-2, a radial orbit accuracy of about 2–9 cm was achieved, with an rms of fit of the tracking data of about 0.64 mm/s. Furthermore, it was found that the coordinates of the ground stations can be determined with an accuracy of the order of 2–5 cm after removal of common rotations, and translations.

Using a slightly different model for atmospheric drag, but the same gravity model, precise orbits of TOPEX/Poseidon from DORIS tracking data were determined with a radial orbit accuracy of the order of 4–5 cm, which is far within the 13 cm mission requirement. This conclusion is based on the analysis of 1-day overlap of successive 11-day orbits, and the comparisons with orbits computed from satellite laser tracking (SLR) and from the combination of SLR and DORIS tracking. Results indicate a consistency between the different orbits of 1–4 cm, 4–20 cm, and 6–13 cm in the radial, cross-track, and along-track directions, respectively. The residual rms is about 4–5 cm for SLR data and 0.56 mm/s for DORIS tracking. These numbers are roughly twice as large as the system noise levels, reflecting the fact that there are still some modeling errors left.     

Issues of exploration: human health and wellbeing during a mission to Mars.

Today, the tools are in our hands to enable us to travel away from our home planet and become citizens of the solar system. Even now, we are seriously beginning to develop the robust infrastructure that will make the 21st century the Century of Space Travel. But this bold step must be taken with due concern for the health, safety and wellbeing of future space explorers. Our long experience with space biomedical research convinces us that, if we are to deal effectively with the medical and biomedical issues of exploration, then dramatic and bold steps are also necessary in this field. We can no longer treat the human body as if it were composed of muscles, bones, heart and brain acting independently. Instead, we must lead the effort to develop a fully integrated view of the body, with all parts connected and fully interacting in a realistic way. This paper will present the status of current (2000) plans by the National Space Biomedical Research Institute to initiate research in this area of integrative physiology and medicine. Specifically, three example projects are discussed as potential stepping stones towards the ultimate goal of producing a digital human. These projects relate to developing a functional model of the human musculoskeletal system and the heart.     

Gravisensing: ionic responses, cytoskeleton and amyloplast behavior.

In Zea mays L., changes in orientation of stems are perceived by the pulvinal tissue, which responds to the stimulus by differential growth resulting in upward bending of the stem. Gravity is perceived in the bundle sheath cells, which contain amyloplasts that sediment to the new cell base when a change in the gravity vector occurs. The mechanism by which the mechanical signal is transduced into a physiological response is so far unknown for any gravity perceiving tissue. It is hypothesized that this involves interactions of amyloplasts with the plasma membrane and/or ER via cytoskeletal elements. To gain further insights into this process we monitored amyloplast movements in response to gravistimulation. In a pharmacological approach we investigated how the dynamics of plastid sedimentation are affected by actin and microtubule (MT) disrupting drugs. Dark grown caulonemal filaments of the moss Physcomitrella patens respond to gravity vector changes with a reorientation of tip growth away from the gravity vector. MT distributions in tip cells were monitored over time and MTs were seen to accumulate preferentially on the lower flank of the tip 30 min after a 90 degree turn. Using a self-referencing Ca2+ selective ion probe, we found that growing caulonemal filaments exhibit a Ca2+ influx at the apical dome, similar to that reported previously for other tip growing cells. However, in gravistimulated Physcomitrella filaments the region of Ca2+ influx is not confined to the apex, but extends about 60 micrometers along the upper side of the filament. Our results indicate an asymmetry in the Ca2+ flux pattern between the upper and side of the filament suggesting differential activation of Ca2+ permeable channels at the plasma membrane.     

A space radiation transport method development.

Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design.     

Pilot error in automated systems shown by altitude deviationreports

Over 8,000 altitude deviations are reported to NASA's Aviation Safety Reporting System each year. This is almost one an hour. The narratives of pilot incidents relate how errors made in the automation-assisted altitude change task are caused by the difficulty pilots are having interacting with automatic systems. This paper discusses the impact of increased automation in glass-cockpit airliners on the altitude deviations reported by pilots. By observing the way information is processed by the cockpit system, the author suggests that the philosophies of design and training need to change in order to facilitate, not debilitate, the aircrew