The role of DNA repair on cell killing by charged particles.

It can be noted that it is not simple double strand breaks (dsb) but the non-reparable breaks that are associated with high biological effectiveness in the cell killing effect for high LET radiation. Here, we have examined the effectiveness of fast neutrons and low (initial energy = 12 MeV/u) or high (135 MeV/u) energy charged particles on cell death in 19 mammalian cell lines including radiosensitive mutants. Some of the radiosensitive lines were deficient in DNA dsb repair such as LX830, M10, V3, and L5178Y-S cells and showed lower values of relative biological effectiveness (RBE) for fast neutrons if compared with their parent cell lines. The other lines of human ataxia-telangiectasia fibroblasts, irs 1, irs 2, irs 3 and irs1SF cells, which were also radiosensitive but known as proficient in dsb repair, showed moderated RBEs. Dsb repair deficient mutants showed low RBE values for heavy ions. These experimental findings suggest that the DNA repair system does not play a major role against the attack of high linear energy transfer (LET) radiations. Therefore, we hypothesize that a main cause of cell death induced by high LET radiations is due to non-reparable dsb, which are produced at a higher rate compared to low LET radiations.     

The heliolongitudinal distribution of solar flares associated with solar proton events.

We find that the heliolongitudinal distribution of solar flares associated with earth-observed solar proton events is a function of the particle measurement energy. For solar proton events containing fluxes with energies exceeding 1 GeV, we find a Gaussian distribution about the probable root of the Archimedean spiral favorable propagation path leading from the earth to the sun. This distribution is modified as the detection threshold is lowered. For > 100 MeV solar proton events with fluxes > or = 10 protons (cm2-sec-ster)-1 we find the distribution becomes wider with a secondary peak near the solar central meridian. When the threshold is lowered to 10 MeV the distribution further evolves. For > 10 MeV solar proton events having a flux threshold at 10 protons (cm2-sec-ster)-1 the distribution can be considered to be a composite of two Gaussians. One distribution is centered about the probable root of the Archimedean spiral favorable propagation path leading from the earth to the sun, and the other is centered about the solar central meridian. For large flux solar proton events, those with flux threshold of 1000 (cm2-sec-ster)-1 at energies > 10 MeV, we find the distribution is rather flat for about 40 degrees either side of central meridian.     

AFIT neural network research

A brief summary of research done at the Air Force Institute of Technology (AFIT) in the area of neural networks is provided. It has been shown that backpropagation, used for feedforward artificial neural networks, is just a degenerate version of an extended Kalman filter, and that networks can do about as well as the optimum statistical classification technique. A method of finding the importance of features for use by a neural network classifier has been determined. Techniques for using neural networks for image segmentation have been developed. In optical pattern recognition, techniques that allow the processing of real FLIR (forward-looking infrared) images with existing binary spatial light modulators have been devised. An optical direction of arrival detector applicable to laser illumination direction determination has been designed and tested; the design is similar to a fly's eye. Coated mirrors for the optical confocal Fabry-Perot interferometer have been designed, specified, fabricated, and installed. Significant progress has been made in the use of neural networks for processing multiple-feature sets for speech recognition     

A wavelet multiresolution analysis for spatio-temporal signals

The wavelet filters of the conventional 3D multiresolution analysis possess homogeneous spatial and temporal frequency characteristics which limits one's ability to match filter frequency characteristics to signal frequency behavior. Also, the conventional 3D multiresolution analysis employs an oct-tree decomposition structure which restricts the analysis of signal details to identical resolutions in space and time. This paper presents a 3D wavelet multiresolution analysis constructed from nonhomogeneous spatial and temporal filters, and an orthogonal sub-band coding scheme that decouples the spatial and temporal decomposition processes     

Simulation of fast ablation

A brief review of studies on simulation and control of a porous cooling process taking into account material transpiration is given. An approximated solution for an equation of the one-dimensional problem of fast ablation is also presented.     

Design and implementation of near-field, wideband synthetic aperture beamformers

A coarray-based near-field, wideband synthetic aperture beamformer using stepped-frequency signal synthesis and post-data acquisition processing is presented. While coarray techniques offer significant reduction in the number of array elements for a given angular resolution, the hybrid subarray-stepped frequency realization of wideband systems simplifies implementations and offers flexibility in beamforming. Proof of concept is provided using real data collected in an anechoic chamber for several pulse shapes and array weightings.     

Survey of current situation in radiation belt modeling.

The study of Earth's radiation belts is one of the oldest subjects in space physics. Despite the tremendous progress made in the last four decades, we still lack a complete understanding of the radiation belts in terms of their configurations, dynamics, and detailed physical accounts of their sources and sinks. The static nature of early empirical trapped radiation models, for examples, the NASA AP-8 and AE-8 models, renders those models inappropriate for predicting short-term radiation belt behaviors associated with geomagnetic storms and substorms. Due to incomplete data coverage, these models are also inaccurate at low altitudes (e.g., <1000 km) where many robotic and human space flights occur. The availability of radiation data from modern space missions and advancement in physical modeling and data management techniques have now allowed the development of new empirical and physical radiation belt models. In this paper, we will review the status of modern radiation belt modeling.     

Experimental study of damping properties of a composite torsion bar in the helicopter main rotor hingeless hub

The results of the experimental studies of damping characteristics of a composite torsion bar in the helicopter main rotor hingeless hub are presented. A variant of their improvement is considered.     

The finite element analysis of shells of revolution with a branching meridian

We present an algorithm for calculating the shells of revolution with the branching meridian using the triangular finite elements, the rigidity matrices of which are formed based on the vector method of displacement interpolation [1]. The correct kinematic and static conditions of shell conjugation on the line of their coupling have been developed. The shell structure consisting of a cylinder and adjacent shells is calculated under various conditions of support.     

Analysis of shells of revolution under symmetrical loading using the quadrature method

The application of the quadrature method [1] to analyzing the shells of revolution under symmetrical loading relative to the zero meridian is considered. The method can be treated as a generalization of the method presented in [2] to solve the Volterra integral equation of the second kind.