The role of repair in the survival of mammalian cells from heavy ion irradiation: approximation to the ideal case of target theory.

Theories of cellular radiation sensitivity that preclude a significant role for cellular repair processes in the final biological expression of cellular damage induced by ionizing radiation are unsound. Experiments are discussed here in which the cell-cycle dependency of the repair deficiency of the S/S variant, of the L5178Y murine leukemic lymphoblast was examined by treatment with the heavy ions, 20Ne, 28Si, 40Ar, 56Fe and 93Nb. Evidence from those studies, which will be described in detail elsewhere, provide support for the notion that as the linear energy transfer (LET infinity) of the incident radiation increases the ability of the S/S cell to repair radiation damage decreases until effectively it is eliminated around 500 keV/micrometer. In the region of the latter LET infinity value, the behavior of the S/S cell approximates the ideal case of target theory where post-irradiation metabolism (repair) does not influence cell survival. The expression of this phenomenon among different cell types and tissues will depend upon the actual repair systems involved and other considerations.     

Pilots for space tourism

This article sheds light on the key player needed for any space tourism adventure: the pilot who flies the spacecraft. The paper addresses the potential benefits of including a pilot at the controls when designing a space tourism spacecraft. It examines the basic qualifications and advanced skills required of space tourism pilots and discusses key training requirements for selected pilots and space pilots' pay and benefits. In addition, the research concludes that, just as the pioneers of passenger transport in aviation entertained and captured the interest of their passengers, the space pilot should have the skills of a tour guide.     

Propagating MHD Waves in Coronal Holes

Coronal holes are the coolest and darkest regions of the upper solar atmosphere, as observed both on the solar disk and above the solar limb. Coronal holes are associated with rapidly expanding open magnetic fields and the acceleration of the high-speed solar wind. During the years of the solar minima, coronal holes are generally confined to the Sun??s polar regions, while at solar maxima they can also be found at lower latitudes. Waves, observed via remote sensing and detected in-situ in the wind streams, are most likely responsible for the wind and several theoretical models describe the role of MHD waves in the acceleration of the fast solar wind. This paper reviews the observational evidences of detection of propagating waves in these regions. The characteristics of the waves, like periodicities, amplitude, speed provide input parameters and also act as constraints on theoretical models of coronal heating and solar wind acceleration.     

Advanced materials for next generation NiMH portable, HEV and EVbatteries

While Ovonic NiMH batteries are already in high volume commercial production for portable applications, advances in materials technology have enabled performance improvements in specific energy (100 Wh/kg), specific power (600-1000 W/kg), high temperature operation, charge retention, and voltage stability. Concurrent with technology advances, Ovonic NiMH batteries have established performance and commercial milestones in electric vehicles, hybrid electric vehicles, as well as scooter, motorcycle and bicycle applications. As important as these advances, significant manufacturing cost reductions have also occurred which allow continued growth of NiMH technology. In this paper, advances in performance, applications and cost reduction are discussed with particular emphasis on the improved proprietary metal hydride and nickel hydroxide materials that make such advances possible     

Analysis of nonlinear deformation and stability of reinforced elliptic cylindrical shells under bending with internal pressure

A finite element statement of solving problems on stability of reinforced elliptic cylindrical shells taking into account momentness and nonlinearity of their subcritical stress strain state is presented. The explicit expressions for displacements of noncircular cylindrical shell elements as rigid bodies are determined by integrating the equations obtained by equating the components of linear strains to zero. These expressions were used to construct the form functions for an efficient quadrilateral finite element of natural curvature. An efficient numerical algorithm of nonlinear deformation and stability of shells was developed. The stability of reinforced elliptic cylindrical shells under combined loading by bending moment, transverse boundary force and internal pressure is analyzed. We also examine how the critical loads are affected by the strain nonlinearity and ellipticity of shell deformation at the subcritical stage.     

DORIS geodesy: A dynamic determination of geocentre location

Geoscience Australia contributed a multi-satellite, multi-year weekly time series to the International DORIS Service combined submission for the construction of International Terrestrial Reference Frame 2008 (ITRF2008). This contributing solution was extended to a study of the capability of DORIS to dynamically estimate the variation in the geocentre location. Two solutions, comprising different constraint configurations of the tracking network, were undertaken. The respective DORIS satellite orbit solutions (SPOT-2, SPOT-4, SPOT-5 and Envisat) were verified and validated by comparison with those produced at the Goddard Space Flight Center (GSFC), DORIS Analysis Centre, for computational consistency and standards. In addition, in the case of Envisat, the trajectories from the GA determined SLR and DORIS orbits were compared. The results for weekly dynamic geocentre estimates from the two constraint configurations were benchmarked against the geometric geocentre estimates from the IDS-2 combined solution. This established that DORIS is capable of determining the dynamic geocentre variation by estimating the degree one spherical harmonic coefficients of the Earth’s gravity potential. It was established that constrained configurations produced similar results for the geocentre location and consequently similar annual amplitudes. For the minimally constrained configuration Greenbelt–Kitab, the mean of the uncertainties of the geocentre location were 2.3, 2.3 and 7.6 mm and RMS of the mean uncertainties were 1.9, 1.2 and 3.5 mm for the X, Y and Z components, respectively. For GA_IDS-2_Datum constrained configuration, the mean of the uncertainties of the geocentre location were 1.7, 1.7 and 6.2 mm and RMS of the mean uncertainties were 0.9, 0.7 and 2.9 mm for the X, Y and Z components, respectively. The mean of the differences of the two DORIS dynamic geocentre solutions with respect to the IDS-2 combination were 1.6, 4.0 and 5.1 mm with an RMS of the mean 21.2, 14.0 and 31.5 mm for the Greenbelt–Kitab configuration and 4.1, 3.9 and 4.3 mm with an RMS 8.1, 9.0 and 28.6 mm for the GA_IDS-2_Datum constraint configuration. The annual amplitudes for each component were estimated to be 5.3, 10.8 and 11.0 mm for the Greenbelt–Kitab configuration and 5.3, 9.3 and 9.4 mm for the GA_IDS-2_Datum constraint configuration. The two DORIS determined dynamic geocentre solutions were compared to the SLR determined dynamic solution (which was determined from the same process of the GA contribution to the ITRF2008 ILRS combination) gave mean differences of 3.3, −4.7 and 2.5 mm with an RMS of 20.7, 17.5 and 28.0 mm for the X, Y and Z components, respectively for the Greenbelt–Kitab configuration and 1.1, −5.4 and 4.4 mm with an RMS of 9.7, 13.3 and 24.9 mm for the GA_IDS-2_Datum configuration. The larger variability is reflected in the respective amplitudes. As a comparison, the annual amplitudes of the SLR determined dynamic geocentre are 0.9, 1.0 and 6.8 mm in the X, Y and Z components. The results from this study indicate that there is potential to achieve precise dynamically determined geocentre from DORIS.     

Testing for Year 2000 readiness: technical and management issues

The approach of the Year 2000 (Y2K) has called into question the condition of readiness of computer systems upon which organizations depend. Will these systems operate reliably after midnight, January 1, 2000, or will problems associated with date calculations cause failures that adversely affect users? This question has caused organizations to identify their critical systems, test these systems for Y2K problems, and take corrective action where necessary to ensure Y2K readiness. This paper examines various technical and management issues that Southwest Research Institute has dealt with in solving these problems     

Target-Handling Capacity of a Phased-Array Tracking Radar

The factors which affect the target-handling capacity of an agile-beamelectronically scanned multitarget-tracking radar are reviewed and analyze.Consideration is given to the choice of strategy for dwell allocation amongtargets, the choice of trajectory extrapolation algorithms for target tracking, and the determination of saturation target acquisition rates. Emphasisis placed upon radar systems with control computers having limited speed and memory, and recommendations are made for allocation strategy and targetytracking algorithms, based on uniform sampling, to be used in maximizing thetarget-handling capacity in this situation.