Topological biosignatures: large-scale structure of chemical networks from biology and astrochemistry

The chemical basis of life involves more than simply the presence of biological molecules; biochemical systems embody a complex network of reactions with characteristic topological features. At the same time, chemical complexity is also present in nonbiological contexts, inviting us to clarify the relationship between chemistry and life through comparative studies. This study examines chemical networks from biology (the metabolism of E. coli) and astronomy (gas-phase reactions in dark molecular clouds) to establish common topological features that may be generic for any complex chemical system, as well as clear differences that may be topological signatures of life. The biological and astrochemical networks exhibit different scaling behaviors, and the network motifs found in the two systems show similarities as well as significant differences. The PageRank algorithm was used to quantify the degree to which individual species act primarily as products or reactants; in the metabolic network, these two roles are nearly identical for most species, whereas the astrochemical network shows a clearer partitioning into reactants and products.     

Bacterial community in ancient Siberian permafrost as characterized by culture and culture-independent methods

The microbial composition of ancient permafrost sediments from the Kolyma lowland of Northeast Eurasia was examined through culture and culture-independent approaches. These sediments have been continuously frozen for 5,000 to 2-3 million years. A total of 265 Bacteria 16S rRNA gene sequences were amplified from the permafrost total-community genomic DNA and screened by amplified ribosomal 16S rRNA restriction analysis. Members of three major lineages were found: gamma-Proteobacteria (mostly Xanthomonadaceae), Actinobacteria, and Firmicutes. We also determined partial 16S rRNA gene sequences of 49 isolates from a collection of 462 aerobes isolated from these sediments. The bacteria included Actinomycetales (Arthrobacter and Microbacteriaceae); followed by the Firmicutes (Exiguobacterium and Planomicrobium); the Bacteroidetes (Flavobacterium); the gamma-Proteobacteria (Psychrobacter); and the alpha-Proteobacteria (Sphingomonas). Both culture and culture-independent approaches showed the presence of high and low G+C Gram-positive bacteria and gamma-Proteobacteria. Some of the 16S rRNA gene sequences of environmental clones matched those of Arthrobacter isolates. Two-thirds of the isolates grew at -2.5 degrees C, indicating that they are psychroactive, and all are closely related to phylogenetic groups with strains from other cold environments, mostly commonly from Antarctica. The culturable and non-culturable microorganisms found in the terrestrial permafrost provide a prototype for possible life on the cryogenic planets of the Solar System.     

Theory of Errors of a Multigimbal, Elastically Supported, Tuned Gyroscope

An elastically supported, tuned gyroscope is a complex device, but experience has shown that it can be represented by mathematical models by means of which practically all of its characteristic errors can be analyzed and predicted with good accuracy. The gyro angular transfer function, derived in [1], serves as an excellent basis of evaluation of errors due to asymmetries of the gimballing system and effects of rotor angular offsets. The gyro translational transfer function, derived in this paper, may be used in the analysis of errors caused by linear acceleration inputs.     

Communicating bioastronautics research to students, families and the nation

The National Space Biomedical Research Institute (NSBRI) is supporting the National Aeronautics and Space Administration's (NASA) education mission through a comprehensive Education and Public Outreach Program (EPOP) that communicates the excitement and significance of space biology to schools, families, and lay audiences. The EPOP is comprised of eight academic institutions: Baylor College of Medicine, Massachusetts Institute of Technology, Morehouse School of Medicine, Mount Sinai School of Medicine, Texas A&M University, University of Texas Medical Branch Galveston, Rice University, and the University of Washington. This paper describes the programs and products created by the EPOP to promote space life science education in schools and among the general public. To date, these activities have reached thousands of teachers and students around the US and have been rated very highly.     

Summary of the workshop on gamma-ray burst afterglows at the 34th COSPAR meeting

A summary is given of the presentations at the COSPAR workshop on γ-ray bursts with some personal commentary on the contributions, the SN/GRB connection, and on the role of magnetic fields in γ-ray bursts and their afterglows. Of special interest were the accumulated arguments for strong collimation and associated reduction in the total required energy for γ-ray bursts. Significant discussion was also devoted to the issues associated with iron and metal lines in X-ray spectra. It is important to note that some of the afterglows seem to require ambient densities 1 g cm⁻³, rather incompatible with a massive star environment. Of associated difficulty is the fact that few, if any, afterglows seem consistent with the r⁻² wind expected for a massive star model. There are reasons to think that if γ-ray bursts are associated with supernovae they are of Type Ic. This suggests that any wind present might be rich in carbon and oxygen, not hydrogen or helium. If γ-ray bursts are narrowly collimated, then the burst is only probing a small portion of any wind, perhaps just that time-dependent and isotropic structure directly along the rotation axis. The characteristics of “hypernovae” may be the result of orientation effects in a mildly inhomogeneous set of progenitors, rather than requiring an excessive total energy or luminosity. The recent event GRB 021004 provided a rich photometric and spectroscopic record and perhaps the most direct evidence yet for the association of a specific γ-ray burst with a massive star progenitor. If the magnetic field plays a significant role in launching a relativistic γ-ray burst jet from within a collapsing star, then the magnetic field may also play a role in the propagation, collimation, and stability of that jet within and beyond the star. The magneto-rotational instability (MRI) can operate under conditions of moderate rotation. This means that the MRI will be at work generating strong fields exponentially rapidly even as the disk of material begins to form and makes a transition from a non-Keplerian to quasi-Keplerian flow in the collapsar and related models.     

Multiple generations of carbon in the apex chert and implications for preservation of microfossils

While the Apex chert is one of the most well-studied Archean deposits on Earth, its formation history is still not fully understood. Here, we present Raman spectroscopic data collected on the carbonaceous material (CM) present within the matrix of the Apex chert. These data, collected within a paragenetic framework, reveal two different phases of CM deposited within separate phases of quartz matrix. These multiple generations of CM illustrate the difficulty of searching for signs of life in these rocks and, by extension, in other Archean sequences.     

四川烹饪:火辣辣的口味火辣辣的性情

"西餐很乏味,没味没趣,"在成都最好的川菜馆之一蜀风园,侯伟一边吃着清蒸牛蛙一边说:"小孩子倒是喜欢吃西餐,但四川人很挑剔,如果味道不好,我们不会吃."     

Understanding high-density matter through analysis of surface spectral lines and burst oscillations from accreting neutron stars

We discuss millisecond period brightness oscillations and surface atomic spectral lines observed during type I X-ray bursts from a neutron star in a low mass X-ray binary system. We show that modeling of these phenomena can constrain models of the dense cold matter at the cores of neutron stars. We demonstrate that, even for a broad and asymmetric spectral line, the stellar radius-to-mass ratio can be inferred to better than 5%. We also fit our theoretical models to the burst oscillation data of the low mass X-ray binary XTE J1814-338, and find that the 90% confidence lower limit of the neutron star’s dimensionless radius-to-mass ratio is 4.2.     

Gender specific changes in cortical activation patterns during exposure to artificial gravity

Keeping astronauts healthy during long duration spaceflight remains a challenge. Artificial gravity (AG) generated by a short arm human centrifuges (SAHC) is proposed as the next generation of integrated countermeasure devices that will allow human beings to safely spend extended durations in space, although comparatively little is known about any psychological side effects of AG on brain function.