应用绿色半导体量子点进行乳腺癌原位成像

乳腺癌是癌症中引起妇女死亡的首要因素。本文采用绿色量子点作为荧光显色材料，建立了一种用于早期乳腺癌诊断的原位成像技术。利用生物素标记的抗HER2／neu抗体与乳腺癌细胞表面表达的HER2结合的特点，然后用偶联绿色量子点的链霉亲和素作为荧光检测标记物，与HER2抗原抗体复合物中的生物素发生特异结合，检测出乳腺癌细胞的存在。结果表明，在荧光显微镜下用绿色量子点原位显色的乳腺癌细胞，相对有机染料组显色亮度增强，故检测灵敏度有所提高。     

Sandwich module prototype progress for space solar power

Space solar power (SSP) has been broadly defined as the collection of solar energy in space and its wireless transmission for use on earth. This approach potentially gives the benefit of provision of baseload power while avoiding the losses due to the day/night cycle and tropospheric effects that are associated with terrestrial solar power. Proponents have contended that the implementation of such systems could offer energy security, environmental, and technological advantages to those who would undertake their development. Among recent implementations commonly proposed for SSP, the modular symmetrical concentrator (MSC) and other modular concepts have received considerable attention. Each employs an array of modules for performing conversion of concentrated sunlight into microwaves or laser beams for transmission to earth. While prototypes of such modules have been designed and developed previously by several groups, none have been subjected to the challenging conditions inherent to the space environment and the possible solar concentration levels in which an array of modules might be required to operate. The research described herein details our team's efforts in the development of photovoltaic arrays, power electronics, microwave conversion electronics, and antennas for microwave-based “sandwich” module prototypes. The implementation status and testing results of the prototypes are reviewed.     

InSight Mars Lander Robotics Instrument Deployment System

The InSight Mars Lander is equipped with an Instrument Deployment System (IDS) and science payload with accompanying auxiliary peripherals mounted on the Lander. The InSight science payload includes a seismometer (SEIS) and Wind and Thermal Shield (WTS), heat flow probe (Heat Flow and Physical Properties Package, HP³) and a precision tracking system (RISE) to measure the size and state of the core, mantle and crust of Mars. The InSight flight system is a close copy of the Mars Phoenix Lander and comprises a Lander, cruise stage, heatshield and backshell. The IDS comprises an Instrument Deployment Arm (IDA), scoop, five finger “claw” grapple, motor controller, arm-mounted Instrument Deployment Camera (IDC), lander-mounted Instrument Context Camera (ICC), and control software. IDS is responsible for the first precision robotic instrument placement and release of SEIS and HP³ on a planetary surface that will enable scientists to perform the first comprehensive surface-based geophysical investigation of Mars’ interior structure. This paper describes the design and operations of the Instrument Deployment Systems (IDS), a critical subsystem of the InSight Mars Lander necessary to achieve the primary scientific goals of the mission including robotic arm geology and physical properties (soil mechanics) investigations at the Landing site. In addition, we present test results of flight IDS Verification and Validation activities including thermal characterization and InSight 2017 Assembly, Test, and Launch Operations (ATLO), Deployment Scenario Test at Lockheed Martin, Denver, where all the flight payloads were successfully deployed with a balloon gravity offload fixture to compensate for Mars to Earth gravity.     

Inferring Nighttime Ionospheric Parameters with the Far Ultraviolet Imager Onboard the Ionospheric Connection Explorer

The Ionospheric Connection Explorer (ICON) Far Ultraviolet (FUV) imager, ICON FUV, will measure altitude profiles of OI 135.6 nm emissions to infer nighttime ionospheric parameters. Accurate estimation of the ionospheric state requires the development of a comprehensive radiative transfer model from first principles to quantify the effects of physical processes on the production and transport of the 135.6 nm photons in the ionosphere including the mutual neutralization contribution as well as the effect of resonant scattering by atomic oxygen and pure absorption by oxygen molecules. This forward model is then used in conjunction with a constrained optimization algorithm to invert the anticipated ICON FUV line-of-sight integrated measurements. In this paper, we describe the connection between ICON FUV measurements and the nighttime ionosphere, along with the approach to inverting the measured emission profiles to derive the associated O⁺ profiles from 150–450 km in the nighttime ionosphere that directly reflect the electron density in the F-region of the ionosphere.     

Electron Physics of Asymmetric Magnetic Field Reconnection

There have been many significant advances in understanding magnetic field reconnection as a result of improved space measurements and two-dimensional computer simulations. While reviews of recent work have tended to focus on symmetric reconnection on ion and larger spatial scales, the present review will focus on asymmetric reconnection and on electron scale physics involving the reconnection site, parallel electric fields, and electron acceleration.     

The dynamics and control of the CubeSail mission: A solar sailing demonstration

The CubeSail mission is a low-cost demonstration of the UltraSail solar sailing concept (, ,  and ), using two near-identical CubeSat satellites to deploy a 260 m-long, 20 m² reflecting film. The two satellites are launched as a unit, detumbled, and separated, with the film unwinding symmetrically from motorized reels. The conformity to the CubeSat specification allows for reduction in launch costs as a secondary payload and utilization of the University of Illinois-developed spacecraft bus. The CubeSail demonstration is the first in a series of increasingly-complex missions aimed at validating several spacecraft subsystems, including attitude determination and control, the separation release unit, reel-based film deployment, as well as the dynamical behavior of the sail and on-orbit solar propulsion. The presented work describes dynamical behavior and control methods used during three main phases of the mission. The three phases include initial detumbling and stabilization using magnetic torque actuators, gravity-gradient-based deployment of the film, and steady-state film deformations in low Earth orbit in the presence of external forces of solar radiation pressure, aerodynamic drag, and gravity-gradient.     

The Aster project: Flight to a near-Earth asteroid

The information on the project being developed in Brazil for a flight to binary or triple near-Earth asteroid is presented. The project plans to launch a spacecraft into an orbit around the asteroid and to study the asteroid and its satellite within six months. Main attention is concentrated on the analysis of trajectories of flight to asteroids with both impulsive and low thrust in the period 2013-2020. For comparison, the characteristics of flights to the (45) Eugenia triple asteroid of the Main Belt are also given.     

Long-Term Evolution of the Martian Crust-Mantle System

Lacking plate tectonics and crustal recycling, the long-term evolution of the crust-mantle system of Mars is driven by mantle convection, partial melting, and silicate differentiation. Volcanic landforms such as lava flows, shield volcanoes, volcanic cones, pyroclastic deposits, and dikes are observed on the martian surface, and while activity was widespread during the late Noachian and Hesperian, volcanism became more and more restricted to the Tharsis and Elysium provinces in the Amazonian period. Martian igneous rocks are predominantly basaltic in composition, and remote sensing data, in-situ data, and analysis of the SNC meteorites indicate that magma source regions were located at depths between 80 and 150 km, with degrees of partial melting ranging from 5 to 15 %. Furthermore, magma storage at depth appears to be of limited importance, and secular cooling rates of 30 to 40 K?Gyr^?1 were derived from surface chemistry for the Hesperian and Amazonian periods. These estimates are in general agreement with numerical models of the thermo-chemical evolution of Mars, which predict source region depths of 100 to 200 km, degrees of partial melting between 5 and 20 %, and secular cooling rates of 40 to 50 K?Gyr^?1. In addition, these model predictions largely agree with elastic lithosphere thickness estimates derived from gravity and topography data. Major unknowns related to the evolution of the crust-mantle system are the age of the shergottites, the planet’s initial bulk mantle water content, and its average crustal thickness. Analysis of the SNC meteorites, estimates of the elastic lithosphere thickness, as well as the fact that tidal dissipation takes place in the martian mantle indicate that rheologically significant amounts of water of a few tens of ppm are still present in the interior. However, the exact amount is controversial and estimates range from only a few to more than 200 ppm. Owing to the uncertain formation age of the shergottites it is unclear whether these water contents correspond to the ancient or present mantle. It therefore remains to be investigated whether petrologically significant amounts of water of more than 100 ppm are or have been present in the deep interior. Although models suggest that about 50 % of the incompatible species (H₂O, K, Th, U) have been removed from the mantle, the amount of mantle differentiation remains uncertain because the average crustal thickness is merely constrained to within a factor of two.     

Microphysics of Cosmic Plasmas: Background, Motivation and Objectives

With the maturing of space plasma research in the solar system, a more general approach to plasma physics in general, applied to cosmic plasmas, has become appropriate. There are both similarities and important differences in describing the phenomenology of space plasmas on scales from the Earth’s magnetosphere to galactic and inter-galactic scales. However, there are important aspects in common, related to the microphysics of plasma processes. This introduction to a coordinated collection of papers that address the several aspects of the microphysics of cosmic plasmas that have unifying themes sets out the scope and ambition of the broad sweep of topics covered in the volume, together with an enumeration of the detailed objectives of the coverage.     

X-ray and extreme ultraviolet emissions from comets

There is significant progress in the observations, theory, and understanding of the x-ray and EUV emissions from comets since their discovery in 1996. That discovery was so puzzling because comets appear to be more efficient emitters of x-rays than the Moon by a factor of 80 000. The detected emissions are general properties of comets and have been currently detected and analyzed in thirteen comets from five orbiting observatories. The observational studies before 2000 were based on x-ray cameras and low resolution (E/δE ≈ 1.5-3) instruments and focused on the morphology of xrays, their correlations with gas and dust productions in comets and with the solar x-rays and the solar wind. Even those observations made it possible to choose uniquely charge exchange between the solar wind heavy ions and cometary neutrals as the main excitation process. The recently published spectra are of much better quality and result in the identification of the emissions of the multiply charged ions of O, C, Ne, Mg, and Si which are brought to comets by the solar wind. The observed spectra have been used to study the solar wind composition and its variations. Theoretical analyses of x-ray and EUV photon excitation in comets by charge exchange, scattering of the solar photons by attogram dust particles, energetic electron impact and bremsstrahlung, collisions between cometary and interplanetary dust, and solar x-ray scattering and fluorescence in comets have been made. These analyses confirm charge exchange as the main excitation mechanism, which is responsible for more than 90% of the observed emission, while each of the other processes is limited to a few percent or less. The theory of charge exchange and different methods of calculation for charge exchange are considered. Laboratory studies of charge exchange relevant to the conditions in comets are reviewed. Total and state-selective cross sections of charge exchange measured in the laboratory are tabulated. Simulations of synthetic spectra of charge exchange in comets are discussed. X-ray and EUV emissions from comets are related to different disciplines and fields such as cometary physics, fundamental physics, x-rays spectroscopy, and space physics.This revised version was published online in July 2005 with a corrected cover date.