MEDES clinical research facility as a tool to prepare ISSA space flights

This new multi-disciplinary medical experimentation center provides the ideal scientific, medical and technical environment required for research programs and to prepare international space station Alpha (ISSA) missions, where space and healthcare industries can share their expertise. Different models are available to simulate space flight effects (bed-rest, confinement,...). This is of particular interest for research in Human psychology, physiology, physiopathology and ergonomics, validation of biomedical materials and procedures, testing of drugs, and other healthcare related products. This clinical research facility (CRF) provides valuable services in various fields of Human research requiring healthy volunteers. CRF is widely accessible to national and international, scientific, medical and industrial organisations. Furthermore, users have at their disposal the multi-disciplinary skills of MEDES staff and all MEDES partners on a single site.     

Simulating planetary wave propagation to the upper atmosphere during stratospheric warming events at different mountain wave scenarios

Parameterization schemes of atmospheric normal modes (NMs) and orographic gravity waves (OGWs) have been implemented into the mechanistic Middle and Upper Atmosphere Model (MUAM) simulating atmospheric general circulation. Based on the 12-members ensemble of runs with the MUAM, a composite of the stratospheric warming (SW) has been constructed using the UK Met Office data as the lower boundary conditions. The simulation results show that OGW amplitudes increase at altitudes above 30 km in the Northern Hemisphere after the SW event. At altitudes of about 50 km, OGWs have largest amplitudes over North American and European mountain systems before and during the composite SW, and over Himalayas after the SW. Simulations demonstrate substantial (up to 50–70%) variations of amplitudes of stationary planetary waves (PWs) during and after the SW in the mesosphere-lower thermosphere of the Northern Hemisphere. Westward travelling NMs have amplitude maxima not only in the Northern, but also in the Southern Hemisphere, where these modes have waveguides in the middle and upper atmosphere. Simulated variations of PW and NM amplitudes correspond to changes in the mean zonal wind, EP-fluxes and wave refractive index at different phases of the composite SW events. Inclusion of the parameterization of OGW effects leads to decreases in amplitudes (up to 15%) of almost all SPWs before and after the SW event and their increase (up to 40–60%) after the SW in the stratosphere and mesosphere at middle and high northern latitudes. It is suggested that observed changes in NM amplitudes in the Southern Hemisphere during SW could be caused by divergence of increased southward EP-flux. This EP-flux increases due to OGW drag before SW and extends into the Southern Hemisphere.     

Development of a gas chromatography compatible Sample Processing System (SPS) for the in-situ analysis of refractory organic matter in martian soil: preliminary results

In the frame of the 2009 Mars Science Laboratory (MSL) mission a new sample preparation system (SPS) compatible with gas chromatography–mass spectrometry (GC–MS) has been developed for the in situ analysis of complex organic molecules in the Martian soil. The goal is to detect, if they exist, some of the key compounds that play an important role in life on Earth including carboxylic acids, amino acids and nucleobases.     

Numerical modeling of inhomogeneous orographic wave influence on planetary waves in the middle atmosphere

Parameterization of dynamical and thermal effects of stationary orographic gravity waves (OGWs) generated by the Earth’s surface topography is incorporated into a numerical model of general circulation of the middle and upper atmosphere. Responses of atmospheric general circulation and characteristics of planetary waves at altitudes from the troposphere up to the thermosphere to the effects of OGWs propagating from the earth surface are studied. Changes in atmospheric circulation and amplitudes of planetary waves due to variations of OGW generation and propagation in different seasons are considered. It is shown that during solstices the main OGW dynamical and heat effects occur in the middle atmosphere of winter hemispheres, where changes in planetary wave amplitudes due to OGWs may reach up to 50%. During equinoxes OGW effects are distributed more homogeneously between northern and southern hemispheres.     

Subsidence rate monitoring of Aghajari oil field based on Differential SAR Interferometry

Land subsidence, due to natural or anthropogenic processes, causes significant costs in both economic and structural aspects. That part of subsidence observed most is the result of human activities, which relates to underground exploitation. Since the gradual surface deformation is a consequence of hydrocarbon reservoirs extraction, the process of displacement monitoring is amongst the petroleum industry priorities. Nowadays, Differential SAR Interferometry, in which satellite images are utilized for elevation change detection and analysis – in a millimetre scale, has proved to be a more real-time and cost-effective technology in contrast to the traditional surveying method. In this study, surface displacements in Aghajari oil field, i.e. one of the most industrious Iranian hydrocarbon sites, are being examined using radar observations. As in a number of interferograms, the production wells inspection reveals that surface deformation signals develop likely due to extraction in a period of several months. In other words, different subsidence or uplift rates and deformation styles occur locally depending on the geological conditions and excavation rates in place.     

Investigation into impact of tropical cyclones on the ionosphere using GPS sounding and NCEP/NCAR Reanalysis data

Ionospheric response to tropical cyclones (TCs) was estimated experimentally on the example of three powerful cyclones – KATRINA (23–31 August 2005), RITA (18–26 September 2005), and WILMA (15–25 October 2005). These TCs were active near the USA Atlantic coast. Investigation was based on Total Electron Content (TEC) data from the international network of two-frequency ground-based GPS receivers and the NCEP/NCAR Reanalysis data. We studied the spatial–temporal dynamics of wave TEC disturbances over two periods of ranges (02–20 min and 20–60 min). To select the ionospheric disturbances which were most likely to be associated with the cyclones, maps of TEC disturbances were compared with those of meteorological parameters.     

Effect of track structure and radioprotectors on the induction of oncogenic transformation in murine fibroblasts by heavy ions

The oncogenic potential of high-energy ⁵⁶Fe particles (1 GeV/nucleon) accelerated with the Alternating Gradient Synchrotron at the Brookhaven National Laboratory was examined utilizing the mouse C3H 10T1/2 cell model. The dose-averaged LET for high-energy ⁵⁶Fe is estimated to be 143 keV/μm with the exposure conditions used in this study. For ⁵⁶Fe ions, the maximum relative biological effectiveness (RBE_max) values for cell survival and oncogenic transformation were 7.71 and 16.5 respectively. Compared to 150 keV/μm ⁴He nuclei, high-energy ⁵⁶Fe nuclei were significantly less effective in cell killing and oncogenic induction. The prostaglandin E₁ analog misoprostol, an effective oncoprotector of C3H 10T1/2 cells exposed to X rays, was evaluated for its potential as a radioprotector of oncogenic transformation with high-energy ⁵⁶Fe. Exposure of cells to misoprostol did not alter ⁵⁶Fe cytotoxicity or the rate of ⁵⁶Fe-induced oncogenic transformation.     

Spectroscopic data and Stark broadening of Cu I and Ag I spectral lines: Selection and analysis

Optical emission and linear laser absorption spectroscopy techniques were used in investigation of plasma with copper and silver admixture. The method of selection of spectral lines and spectroscopic data with the aim of diagnostics of multicomponent air plasma with two metal vapors admixture was developed. Energy level populations behavior on the Boltzmann plot were used for Cu I and Ag I spectroscopic data selection. In this way the selection of spectroscopic data for some of Cu I and Ag I lines was realized. Stark broadening parameters of Cu I and Ag I were examined. Experimentally obtained temperature and electron density radial distributions were used in the calculation of plasma composition in the assumption of local thermodynamic equilibrium. Linear laser absorption spectroscopy was used to examine the state of plasma.     

A Gaussian Mixture PHD Filter for Jump Markov System Models

The probability hypothesis density (PHD) filter is an attractive approach to tracking an unknown and time-varying number of targets in the presence of data association uncertainty, clutter, noise, and detection uncertainty. The PHD filter admits a closed-form solution for a linear Gaussian multi-target model. However, this model is not general enough to accommodate maneuvering targets that switch between several models. In this paper, we generalize the notion of linear jump Markov systems to the multiple target case to accommodate births, deaths, and switching dynamics. We then derive a closed-form solution to the PHD recursion for the proposed linear Gaussian jump Markov multi-target model. Based on this an efficient method for tracking multiple maneuvering targets that switch between a set of linear Gaussian models is developed. An analytic implementation of the PHD filter using statistical linear regression technique is also proposed for targets that switch between a set of nonlinear models. We demonstrate through simulations that the proposed PHD filters are effective in tracking multiple maneuvering targets.