Histologic effects of high energy electron and proton irradiation of rat brain detected with a silver-degeneration stain.

Application of the degeneration sensitive, cupric-silver staining method to brain sections of male Sprague-Dawley rats irradiated 4 days before sacrifice with 155 Mev protons, 2-8 Gy at 1 Gy/min (N=6) or 22-l0lGy at 20 Gy/min (N=16) or with 18.6 Mev electrons, 32-67 Gy at 20 Gy/min (N=20), doses which elicit behavioral changes (accelerod or conditioned taste aversion), resulted in a display of degeneration of astrocyte-like cell profiles which were not uniformly distributed. Plots of 'degeneration scores' (counts of profiles in 29 areas) vs. dose for the proton and electron irradiations displayed a linear dose response for protons in the range of 2-8 Gy. In the 20-100 Gy range, for both electrons and protons the points were distributed in a broad band suggesting a saturation curve. The dose range in which these astrocyte-like profiles becomes maximal corresponds well with the dose range for the X-ray eradication of a subtype of astrocytes, 'beta astrocytes'.     

Review of basic medical results of the Salyut-7--Soyuz-T 8-month manned flight.

This paper presents the results of medical investigations performed in the Salyut-7 8-month mission in which a professional physician took part. The paper contains anthropometric measurements, results of investigating the vestibular function, cardiovascular function at rest and in response to multi-step tests (with emphasis on echocardiographic measurements), metabolic parameters and hormonal status. It also discusses medical aspects of the extravehicular activity. The medical investigations, although some new methods were applied, provided the continuity of methodical approaches and data accumulated in previous missions.     

Thermoluminescent dose measurements on-board Salyut type orbital stations.

A small, vibration- and shock-resistant thermoluminescent dosemeter /TLD/ system--named PILLE--was developed at the Health Physics Department of the Central Research Institute for Physics, Budapest, to measure the cosmic radiation dose on board orbital stations. The first on-board measurements with this system were performed /by B. Farkas, the Hungarian astronaut/, on the Salyut-6 space station in 1980. The same instrument was used by other crews in the following years. Doses measured at different sites in Salyut-6 are presented. The dose rates varied from 0.07 to 0.11 mGy.day-1. After the first cosmic measurements, the system was further developed. The minimum detectable dose of the new TLD system is 1 microGy, i.e. less by on order of magnitude than that of the former system. The self-irradiation dose rate of the TLD bulbs is also reduced--by more than one order of magnitude--to 10 nGy.h-1, by the use of potassium-free glass for the bulb envelope. This new type of PILLE TLD system is currently on-board Salyut-7. The dose rates /0.12-0.23 mGy.day-1/ measured in 1983 are presented in detail.     

Space radiation dosimetry with active detections for the scientific program of the second Bulgarian cosmonaut on board the Mir space station.

A dosimetry-radiometry system has been developed at the Space Research Institute of the Bulgarian Academy of Science to measure the fluxes and dose rates on the flight of the second Bulgarian cosmonaut. The dosimetry system is designed for monitoring the different space radiations, such as solar cosmic rays, galactic cosmic rays and trapped particles in the earth radiation belts. The system consists of a battery operated small size detector unit and a "read-write" and telemetry microcomputer unit. The sensitivity of the instrument (3.67 x 10(-8) rad/pulse) permits high resolution measurements of the flux and dose rate along the track of the Mir space station. We report our initial results for the period of the flight between the 7th and 17th June 1988.     

A computer network with SCADA and case tools for on-line process control in greenhouses.

Climate control computers in greenhouses are used to control heating and ventilation, supply water and dilute and dispense nutrients. They integrate models into optimally controlled systems. This paper describes how information technology, as in use in other sectors of industry, is applied to greenhouse control. The introduction of modern software and hardware concepts in horticulture adds power and extra oppurtunities to climate contol in greenhouses.     

Application of ISFETs in closed-loop systems for greenhouses.

In horticulture, growing in artificial substrates such as rockwool is more and more considered to be a sound alternative to growing in soil. This development enables the opportunity to create closed-loop systems which lower the waste of raw materials and reduce pollution of the environment. Applying closed-loop systems needs precise knowledge of the composition of the recirculating nutrient solution. This paper presents basic principles of a measuring system, which can monitor continuously the concentration of nutrients in water. The system is based on ion-selective field effect transistors (ISFETs). By appropriate calibration, a high accuracy is achieved for pH and potassium measurements in the nutrient solution. An accuracy of better than 10% (mMol/l) has been achieved.     

Pathophysiology of motor functions in prolonged manned space flights.

The influence of weightlessness on different parts of the motor system have been studied in crew members of 140 and 175 days space flights. It has been shown that weightlessness affects all parts of the motor system including (i) the leg and trunk muscles, in which severe atonia, a decrease of strength and an increase of electromyographic cost of contraction have been observed, (ii) the proprioceptive elements and the spinal reflex mechanisms in which decreased thresholds accompanied by decreases of maximal amplitude of reflexes and disturbances in cross reflex mechanisms have been found. and (iii) the central mechanisms that control characteristics of postural and locomotor activities. The intensities and durations of disturbances of different parts of the motor system did not correlate to each other, but did correlate with prophylactic activity during space flight. The data suggest a different nature of disturbances caused by weightlessness in different parts of the motor system.     

"Mir" radiation dosimetry results during the solar proton events in September-October 1989.

Using data from dosimetry-radiometry system "Liulin" on board of "Mir"-space station the particle flux and doserate during September-October, 1989 has been studied. The orbit of the station was 379 km perigee, 410 km apogee and 51.6 degrees inclination. Special attention has been paid to the flux and doserate changes inside the station after intensive solar proton events (SPE) on 29 of September, 1989. The comparison between the doses before and after the solar flares shows increase of the calculated mean dose per day by factor of 10 to 200. During the SPE on the 29 of September the additional dose was 310 mrad. The results of the experiment are compared with the data for the solar proton fluxes obtained on the GOES-7 satellite.