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Light is being used as a pre-launch countermeasure to circadian and sleep disruption in astronauts. The effect of light on the circadian system is readily monitored by measurement of plasma melatonin. Our group has established an action spectrum for human melatonin regulation and determined the region of 446-477 nm to be the most potent for suppressing plasma melatonin. The aim of this study was to compare the efficacy of 460 and 555 nm for suppressing melatonin using a within-subjects design. Subjects (N=12) were exposed to equal photon densities (7.18 x 10(12) photons/cm2/s) at 460 and 555 nm. Melatonin suppression was significantly stronger at 460 nm (p<0.02). An extension to the action spectrum showed that 420 nm light at 16 and 32 microW/cm2 significantly suppressed melatonin (p<0.04 and p<0.002). These studies will help optimize lighting countermeasures to circadian and sleep disruption during spaceflight.  相似文献   
2.
We present the first public database of high-energy observations of all known Galactic supernova remnants (SNRs). In Section 1 we introduce the rationale for this work motivated primarily by studying particle acceleration in SNRs, and which aims at bridging the already existing census of Galactic SNRs (primarily made at radio wavelengths) with the ever-growing but diverse observations of these objects at high-energies (in the X-ray and γγ-ray regimes). In Section 2 we show how users can browse the database using a dedicated web front–end (http://www.physics.umanitoba.ca/snr/SNRcat). In Section 3 we give some basic statistics about the records we have collected so far, which provides a summary of our current view of Galactic SNRs. Finally, in Section 4, we discuss some possible extensions of this work. We believe that this catalogue will be useful to both observers and theorists, and timely with the synergy in radio/high-energy SNR studies as well as the upcoming new high-energy missions. A feedback form provided on the website will allow users to provide comments or input, thus helping us keep the database up-to-date with the latest observations.  相似文献   
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