Nuclear fragmentation database for GCR transport code development

A critical need for NASA is the ability to accurately model the transport of heavy ions in the Galactic Cosmic Rays (GCR) through matter, including spacecraft walls, equipment racks, etc. Nuclear interactions are of great importance in the GCR transport problem, as they can cause fragmentation of the incoming ion into lighter ions. Since the radiation dose delivered by a particle is proportional to the square of (charge/velocity), fragmentation reduces the dose delivered by incident ions. The other mechanism by which dose can be reduced is ionization energy loss, which can lead to some particles stopping in the shielding. This is the conventional notion of shielding, but it is not applicable to human spaceflight since the particles in the GCR tend to be too energetic to be stopped in the relatively thin shielding that is possible within payload mass constraints. Our group has measured a large number of fragmentation cross sections, intended to be used as input to, or for validation of, NASA’s radiation transport models. A database containing over 200 charge-changing cross sections and over 2000 fragment production cross sections has been compiled. In this report, we examine in detail the contrast between fragment measurements at large acceptance and small acceptance. We use output from the PHITS Monte Carlo code to test our assumptions using as an example ⁴⁰Ar data (and simulated data) at a beam energy of 650 MeV/nucleon. We also present preliminary analysis in which isotopic resolution was attained for beryllium fragments produced by beams of ¹⁰B and ¹¹B. Future work on the experimental data set will focus on extracting and interpreting production cross sections for light fragments.     

Chromosomal aberrations induced by high-energy iron ions with shielding.

Biophysical models are commonly used to evaluate the effectiveness of shielding in reducing the biological damage caused by cosmic radiation in space flights. To improve and validate these codes biophysical experiments are needed. We have measured the induction of chromosomal aberrations in human peripheral blood lymphocytes exposed in vitro to 500 MeV/n iron ion beams (dose range 0.1-1 Gy) after traversing shields of different material (lucite, aluminium, or lead) and thickness (0-11.3 g/cm2). For comparison, cells were exposed to 200 MeV/n iron ions and to X-rays. Chromosomes were prematurely condensed by a phosphatase inhibitor (calyculin A) to avoid cell-cycle selection produced by the exposure to high-LET heavy-ion beams. Aberrations were scored in chromosomes 1, 2, and 4 following fluorescence in situ hybridization. The fraction of aberrant lymphocytes has been evaluated as a function of the dose at the sample position, and of the fluence of primary 56Fe ions hitting the shield. The influence of shield thickness on the action cross-section for the induction of exchange-type aberrations has been analyzed, and the dose average-LET measured as a function of the shield thickness. These preliminary results prove that the effectiveness of heavy ions is modified by shielding, and the biological damage is dependent upon shield thickness and material.     

Effect of heavy ions on bacterial spores.

Inactivation of B. subtilis spores has been studied using accelerated He, C, N, O and Ne ions. The energy dependence of the inactivation cross sections for heavy ions was very weak and the mean cross sections for carbon ions (0.6-4.7 MeV/amu), nitrogen ions (0.6-4.1 MeV/amu), oxygen ions (0.8-1.1 MeV/amu), and neon ions (2.2-3.7 MeV/amu) were found to be about 0.22, 0.23, 0.26, and 0.33 micrometer2 , respectively. Analysis was carried out along lines similar to Katz's target theory but the parameters were chosen so that they have an experimental basis.     

DNA DSB induced by iron ions in human fibroblasts: LET dependence and shielding efficiency.

This paper reports on DNA DSB induction in human fibroblasts by iron ions of different energies, namely 5, 1 GeV/u, 414 and 115 MeV/u, in absence or presence of different shields (PMMA, Al and Pb). Measure of DNA DSB was performed by calibrated Pulsed Field Gel Electrophoresis using the fragment counting method. The RBE-LET relationships for unshielded and shielded beams were obtained both in terms of dose average LET and of track average LET. Weak dependence on these parameters was observed for DSB induction. The shielding efficiency, evaluated by the ratio between the cross sections for unshielded and shielded beams, depends not only on the shield type and thickness, but also on the beam energy. Protection is only observed at high iron ions energy, especially at 5 GeV/u, where PMMA shield gives higher protection compared to Al or Pb shields of the same thickness expressed in g/cm2.     

Theoretical model of HZE particle fragmentation by hydrogen targets.

The fragmenting of high energy, heavy ions (HZE particles) by hydrogen targets is an important, physical process in several areas of space radiation research. In this work quantum mechanical optical model methods for estimating cross sections for HZE particle fragmentation by hydrogen targets are presented. The cross sections are calculated using a modified abrasion-ablation collision formalism adapted from a nucleus-nucleus collision model. Elemental and isotopic production cross sections are estimated and compared with report measurements for the breakup of neon, sulphur, and iron, nuclei at incident energies between 400 and 910 MeV/nucleon. Good agreement between theory and experiment is obtained.     

Liquid drop model considerations in HZE particle fragmentation by hydrogen

The fragmenting of high energy, heavy ions by hydrogen targets is an important physical process in several areas of space radiation protection research. Quantum mechanical, optical model methods for calculating cross sections for particle fragmentation by hydrogen have been developed from a modified abrasion-ablation collision formalism. The abrasion stage is treated as a knockout process which leaves the residual prefragment in an excited state. In the ablation stage the prefragment deexcites to produce the final fragment. The prefragment excitation energies are estimated from a combination of liquid drop model considerations and frictional-spectator interaction processes. Estimates of elemental and isotopic production cross sections are in good agreement with published cross section measurements.     

Residual chromatin breaks as biodosimetry for cell killing by carbon ions

We have studied the relationship between cell killing and the induction of residual chromatin breaks on various human cell lines and primary cultured cells obtained by biopsy from patients irradiated with either X-rays or heavy-ion beams to identify potential bio-marker of radiosensitivity for radiation-induced cell killing. The carbon-ion beams were accelerated with the Heavy Ion Medical Accelerator in Chiba (HIMAC). Six primary cultures obtained by biopsy from 6 patients with carcinoma of the cervix were irradiated with two different mono-LET beams (LET= 13 keV/μm, 76 keV/μm) and 200kV X rays. Residual chromatin breaks were measured by counting the number of non-rejoining chromatin fragments detected by the premature chromosome condensation (PCC) technique after a 24 hour postirradiation incubation period. The induction rate of residual chromatin breaks per cell per Gy was the highest for 76 keV/μm beams on all of the cells. Our results indicated that cell which was more sensitive to the cell killing was similarly more susceptible to induction of residual chromatin breaks. Furthermore there is a good correlation between these two end points in various cell lines and primary cultured cells. This suggests that the detection of residual chromatin breaks by the PCC technique may be useful as a predictive assay of tumor response to cancer radiotherapy.     

车身薄壁梁结构轻量化设计的理论研究

薄壁梁是车身骨架结构的基本承载单元.为研究车身轻量化对其刚度的影响,首先推导了两端固支梁的静态弯曲和扭转刚度表达式.为获取最佳截面的轻型结构,分别研究了薄壁梁的截面尺寸和壁厚等几何参数对其刚度/质量比的影响.分析了用轻质材料替代传统钢材对其刚度和结构尺寸的影响.对开环与闭环截面梁的刚度/质量比进行了比较.分别找出了能显著影响上述薄壁梁的弯曲和扭转刚度的几何和材料参数.提出了获得高刚度车身典型薄壁梁的轻量化设计原则.     

Measurements and calculations of gamma rays from proton-irradiated thick targets

To help understand planetary gamma-ray spectra, the energies and intensities of gamma rays produced by energetic particles interacting in thick targets were simulated experimentally and numerically. Using the accelerator at RIKEN, thick targets of iron, granite, and gabbro were exposed to 180 or 210 MeV proton beam, and characteristic gamma rays emitted from the targets were measured by Ge detectors. The experimental results were compared with the values calculated by Geant4. The relative intensities of gamma-ray lines from the iron target in the experiment were consistent with those in the calculation within the error of ∼5%. As for stone targets, strong inconsistencies were observed. Further improvement in the calculation code and cross section files, as well as experimental resemblance to space missions are indispensable for gamma-ray spectroscopy.     

（20～400）MeV准单能中子参考辐射场的建立方法CSCD

为了满足对高能中子辐射场测量仪器进行校准的需要,必需建立20MeV以上的准单能中子参考辐射场.对国际上（20～400） MeV准单能中子参考辐射场的建立情况及建立方法进行了调研,可通过7Li（p,n）7Be反应获得该能区准单能中子场,中子束流轮廓可通过转换体和影像板进行测量,辐射场中子能谱可利用液体闪烁探测器或者238U裂变电离室通过飞行时间法进行测量,可建立高效率的反冲质子望远镜作为该能区的中子注量测量初级标准.     

二阶滑模控制在十字梁控制实验系统中的应用

为了削弱传统滑模控制在十字梁实验系统中应用所产生的抖振问题,运用了高阶滑模的设计思想设计了多输入多输出十字梁试验系统的输出跟踪二阶滑模控制器,从而实现了高阶滑模在多输入多输出系统中的应用,并对该系统进行了仿真,仿真结果表明,二阶滑模控制器能够有效地削弱系统产生的抖振.      

日冕背景下的等离子体尾场效应

计算了高能脉冲电子束在冷背景和热背景等离子体条件下产生的等离子体尾场(PWF)大小,讨论了高能电子束的速度、密度、长度对等离子体尾场分布的影响。在这基础上,研究了太阳耀斑脉冲相产生的向外逃逸高能脉冲电子束在日冕背景等离子体条件下激发的等离子体尾场分布以及对其捕获电子的加速。      

Transport of light ions in matter

A recent set of light ion experiments are analyzed using the Green's function method of solving the Boltzmann equation for ions of high charge and energy (the GRNTRN transport code) and the NUCFRG2 fragmentation database generator code. Although the NUCFRG2 code reasonably represents the fragmentation of heavy ions, the effects of light ion fragmentation requires a more detailed nuclear model including shell structure and short range correlations appearing as tightly bound clusters in the light ion nucleus. The most recent NUCFRG2 code is augmented with a quasielastic alpha knockout model and semiempirical adjustments (up to 30 percent in charge removal) in the fragmentation process allowing reasonable agreement with the experiments to be obtained. A final resolution of the appropriate cross sections must await the full development of a coupled channel reaction model in which shell structure and clustering can be accurately evaluated.     

A comparison of total reaction cross section models used in particle and heavy ion transport codes

Understanding the interactions and propagations of high energy protons and heavy ions are essential when trying to estimate the biological effects of Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE) on personnel in space. To be able to calculate the shielding properties of different materials and radiation risks, particle and heavy ion transport codes are needed. In all particle and heavy ion transport codes, the probability function that a projectile particle will collide within a certain distance x in the matter depends on the total reaction cross sections, and the calculated partial fragmentation cross sections scale with the total reaction cross sections. It is therefore crucial that accurate total reaction cross section models are used in the transport calculations. In this paper, different models for calculating nucleon–nucleus and nucleus–nucleus total reaction cross sections are compared with each other and with measurements. The uncertainties in the calculations with the different models are discussed, as well as their overall performances with respect to the available experimental data. Finally, a new compilation of experimental data is briefly presented.     

K-ionization and biological effect.

Experimental inactivation cross sections are compared to vacancy production in inner shell (K-shell) of so-called strategic C, N, O atoms of the DNA: in a trial calculation, atoms on the DNA backbone or just contiguous to it are considered as strategic. Various processes are considered: ionization and electron capture by the primary particle, ionization by secondary electrons. The last phenomenon is shown to be important for highly charged and medium velocity ions. A strong similarity is observed between variations versus LET of inactivation and K-vacancy cross sections, especially with regards to LET values for which they maximize: for K-ionization these maxima occur when the ion impact velocity roughly matches the K electron velocity. It is shown that the "K-hypothesis" allows a quantitative fit of experimental inactivation cross sections if a 4% mean lethal efficiency is attributed to ion-induced K-vacancies in strategic C, N, O atoms.     

Proton lateral broadening distribution comparisons between GRNTRN,MCNPX, and laboratory beam measurements

Recent developments in NASA’s deterministic High charge (Z) and Energy TRaNsport (HZETRN) code have included lateral broadening of primary ion beams due to small-angle multiple Coulomb scattering, and coupling of the ion-nuclear scattering interactions with energy loss and straggling. This new version of HZETRN is based on Green function methods, called GRNTRN, and is suitable for modeling transport with both space environment and laboratory boundary conditions. Multiple scattering processes are a necessary extension to GRNTRN in order to accurately model ion beam experiments, to simulate the physical and biological-effective radiation dose, and to develop new methods and strategies for light-ion radiation therapy. In this paper we compare GRNTRN simulations of proton lateral broadening distributions with beam measurements taken at Loma Linda University Proton Therapy Facility. The simulated and measured lateral broadening distributions are compared for a 250 MeV proton beam on aluminum, polyethylene, polystyrene, bone substitute, iron, and lead target materials. The GRNTRN results are also compared to simulations from the Monte Carlo MCNPX code for the same projectile-target combinations described above.     

W波段多注交错双栅行波放大器的高频特性

提出了一种采用平面线性排列的3个圆形电子注代替平面带状电子注的W波段交错双栅行波放大器微型化慢波高频结构,并重点对其行波传输特性和输入输出耦合特性进行了仿真设计和参数优化.结果表明,这种平面微型化高频结构的行波传输色散特性良好且有很大的工作带宽,所产生的强轴向电场分布非常有利于电子注与高频场的能量交换和相互作用.在保证平面微型结构中圆形注通道直径和带状注通道高度相同的情况下,得到的耦合阻抗是带状注交错双栅慢波高频系统2~3倍,为行波放大器高效率的注波互作用和高功率输出提供了新的研究思路.为了与该交错双栅高频系统相匹配,提出了一种更为简单易行的输入与输出耦合结构,仅采用三周期渐变过渡段就可以实现反射系数S₁₁在较宽频带内低于-20dB的良好结果,更有利于行波放大器未来的工程实现与应用.