Central and regional hemodynamics in prolonged space flights.

This paper presents the results of measuring central and regional (head, forearm, calf) hemodynamics at rest and during provocative tests by the method of tetrapolar rheography in the course of Salyut-6-Soyuz and Salyut-7-Soyuz missions. The measurements were carried out during short-term (19 man-flights of 7 days in duration) and long-term (21 man-flights of 65-237 days in duration) manned missions. At rest, stroke volume (SV) and cardiac output (CO) as well as heart rate (HR) decreased insignificantly (in short-term flights) or remained essentially unchanged (in long-term flights). In prolonged flights CO increased significantly in response to exercise tests due to an increase in HR and the lack of changes in SV. After exercise tests SV and CO decreased as compared to the preflight level. During lower body negative pressure (LBNP) tests HR and CO were slightly higher than preflight. Changes in regional hemodynamics included a distinct decrease of pulse blood filling (PBF) of the calf, a reduction of the tone of large vessels of the calf and small vessels of the forearm. Head examination (in the region of the internal carotid artery) showed a decrease of PBF of the left hemisphere (during flight months 2-8) and a distinct decline of the tone of small vessels, mainly, in the right hemisphere. During LBNP tests the tone of pre- and postcapillary vessels of the brain returned to normal while PBF of the right and left hemisphere vessels declined. It has been shown that regional circulation variations depend on the area examined and are induced by a rearrangement of total hemodynamics of the human body in microgravity. This paper reviews the data concerning changes in central and regional circulation of men in space flights of different duration.     

GPS的空间应用

由于ＧＰＳ系统的特点以及低轨道空间的特殊应用环境，使得ＧＰＳ在空间上的应用存在着与地面应用所不同的特点，本文着重分析这些空间特点对ＧＰＳ定位实现的影响，得出以下结论：对空间用户而言，ＧＰＳ卫星对用户的覆盖有着不同于地面的特点，但可以看出，对９００公里高度以下的低轨用户，ＧＰＳ卫星对用户的覆盖不会比地面更差。同时，电离层延迟误差影响大大降低，对流层延迟误差可以不予考虑。ＧＰＳ系统本身已对相对论效应的长期项影响作了校正，但对空间用户必须重新考虑。由于空间用户运动的规律性，及我们可能对诸如信号的Ｄｏｐｐｌｅｒ频移，多路径干扰等成份作较为准确的估计并加以补偿，从而可能获得高于地面的测量精度     

Effect on the cardiac function of repeated LBNP during a 1-month head down tilt

Cardiovascular assessment by ultrasound methods was performed during two long duration (1 month) Head Down Tilt (HDT) on 6 healthy volunteers. On a first 1 month HDT session, 3 of the 6 subjects (A, B, C) had daily several lower body negative pressure tests (LBNP), whereas the 3 subjects remaining (D, E, F) rested without LBNP. On a second 1 month HDT session subjects D, E, and F had daily LBNP tests and the A, B and C subjects did not. The cardiac function was assessed by Echocardiography, (B mode, TM mode). On all the "6 non LBNP" subjects the left ventricule diastolic volume (LVDV), the stroke volume (SV) and the cardiac output (CO) increase (+10%, -15%) after HDT then decrease and remain inferior (-5%, -5%) or equal to the basal value during the HDT. Immediately after the end of the HDT the heart rate (HR) increase (+10%, +30%) whereas the cardiac parameters decrease weakly (-5%, -10%) and normalize after 3 days of recovery. On the "6 LBNP" subjects the LVDV, SV and CO increase (+10%, 15%) after 1 h HDT as in the previous group then decrease but remain superior (+5%, +15%) or equal to the basal value. After the HDT session, the HR is markedly increased (+20%, +40%) the LVDV and SV decrease (-15%, -20%) whereas the CO increases or decreases depending on the amplitude of the HR variations. These parameters do not completely normalize after 3 day's recovery. Repeated LBNP sessions have a significant effect on the cardiovascular function as it maintains all cardiac parameters above the basal value. The LBNP manoeuvre can be considered as an efficient countermeasure to prevent cardiac disadaptation induced by HDT position and probably microgravity.     

航天器二次电源的低温工作特性研究

由于航天器在深空探测中处于低温环境中,其二次电源的低温工作特性尤为重要。文章首先介绍了航天器二次电源的供电结构;再从组成二次电源的关键元器件着手,对功率半导体器件（功率MOS管和功率二极管）、PWM控制芯片的低温特性进行深入探讨;最后对一个25W/5.8V输出的航天器二次电源在-35~80℃温度范围内工作的试验数据展开分析,这些工作可为后续深空探测任务的实施提供技术储备。     

基于相位扰动的抗有源加性复合干扰技术

针对有源加性复合干扰,研究了基于相位扰动原理的干扰抑制方法。在结合LFM信号特征的基础上,对雷达发射信号的前后脉冲分别附加近似正交的扰动相位,再通过与前一脉冲重复周期相应的匹配滤波器将复合干扰中的欺骗干扰成分加强,并对脉冲压缩结果加以"惩罚",最后采用匹配滤波逆运算恢复出目标回波信号。     

星载光学遥感系统偏振耦合误差分析与修正方法研究

星载遥感器偏振灵敏度带来的偏振测量误差会影响获取数据的准确性,该误差作为系统误差将直接影响到数据应用.文章采用矢量辐射传输模型模拟遥感器(以中等分辨率成像光谱仪为例)入瞳处信号偏振与遥感器偏振耦合特性,分析了遥感器偏振灵敏度分别为2%、5%、7%时,遥感系统的测量误差分布情况,发现偏振耦合误差直接影响获取数据的真实性和...     

Biochemical and hemodynamic changes in normal subjects during acute and rigorous bed rest and ambulation

Rigorous bed rest (RBR) induces significant biochemical and circulatory changes. However, little is known about acute rigorous bed rest (ARBR). Measuring biochemical and circulatory variables during ARBR and RBR the aim of this study was to establish the significance of ARBR effect. Studies were done during 3 days of a pre-bed rest (BR) period and during 7 days of ARBR and RBR period. Thirty normal male individuals aged, 24.1 +/- 6.3 years were chosen as subjects. They were divided equally into three groups: 10 subjects placed under active control conditions served as unrestricted ambulatory control subjects (UACS), 10 subjects submitted to an acute rigorous bed rest served as acute rigorous bed rested subjects (ARBRS) and 10 subjects submitted to a rigorous bed rest served as rigorous bed rested subjects (RBRS). The UACS were maintained under an average running distance of 9.7 km day-1. For the ARBR effect simulation, ARBRS were submitted abruptly to BR for 7 days. They did not have any prior knowledge of the exact date and time when they would be asked to confine to RBR. For the RBR effect simulation, RBRS were subjected to BR for 7 days on a predetermined date and time known to them right away from the start of the study. Plasma renin activity (PRA), plasma cortisol (PC), plasma aldosterone (PA), plasma and urinary sodium (Na) and potassium (K) levels, heart rate (HR), cardiac output (CO), and arterial blood pressure (ABP) increased significantly, and urinary aldosterone (UA), stroke volume (SV) and plasma volume (PV) decreased significantly (p<0.05) in ARBRS and RBRS as compared with their pre-BR values and the values in UACS. Electrolyte, hormonal and hemodynamic responses were significantly (p<0.05) greater and occurred significantly faster (p<0.05) during ARBR than RBR. Parameters change insignificantly (p>0.05) in UACS compared with pre-BR control values. It was concluded that, the more abruptly muscular activity is restricted in experimental subjects while they are very active, the greater hemodynamic and biochemical change there is and probably in individuals whose muscular activity is abruptly terminated after an accident or sudden illness.     

Interaction of mental and orthostatic stressors

We assessed hemodynamic responses induced by orthostatic and mental stressors, using passive head up tilt (HUT) and mental arithmetic (MA), respectively. The 15 healthy males underwent three protocols: (1) HUT alone, (2) MA in supine position and (3) MA+HUT, with sessions randomized and ≥2 weeks apart. In relation to baseline, HUT increased heart rate (HR) (+20.4±7.1 bpm; p<0.001), mean blood pressure (MBP) (+4.7±11.3 mmHg; p<0.05), diastolic blood pressure (DBP) (+6.1±11.6 mmHg; p<0.05) and total peripheral resistance (TPR) (+155±232 dyne*s/cm⁵; p<0.001) but decreased stroke volume (SV) (?33.1±13.4 ml; p<0.001) and cardiac output (CO) (?0.6±1.0 l/min; p<0.01). MA increased HR (+8.0±6.0 bpm; p<0.001), systolic blood pressure (SBP) (+9.0±7.7 mmHg; p<0.001), MBP (+10.0±6.5 mmHg; p<0.001), DBP (+9.5±7.2 mmHg; p<0.001) and CO (+0.6±0.8 l/min; p<0.01). MA+HUT increased HR (+28.8±8.4 bpm; p<0.001), SBP (+4.6±14.3 mmHg; p<0.05), MBP (+11.2±11.6 mmHg; p<0.001), DBP (+13.5±10.1 mmHg; p<0.001) and TPR (+160±199 dyne*s/cm⁵; p<0.001) but SV (?34.5±14.6 ml; p<0.001) decreased. Mental challenge during orthostatic challenge elicited greater increases in heart rate, despite similar reductions in stroke volume such as those during orthostatic stress alone. Overall, cardiac output decreases were less with combinations of mental and orthostatic challenges in comparison to orthostasis alone. This would suggest that carefully chosen mental stressors might affect orthostatic responses of people on standing up. Therefore, additional mental loading could be a useful countermeasure to alleviate the orthostatic responses of persons, particularly in those with histories of dizziness on standing up or on return to earth from the spaceflight environment of microgravity.     

载人航天器密封舱内管路设备维修设计与验证

载人航天器密封舱内配置大量的气、液管路设备,实现管路设备的在轨维修,对于提高长期在轨飞行载人航天器的安全性及使用寿命具有重要意义。文章对某载人航天器再生生保管路设备在轨维修性进行了设计,经地面充分验证后,航天员在轨完成了管路设备维修操作,结果表明本文提出的管路设备在轨维修设计正确、有效,可为载人航天器其他在轨维修设计提供参考。     

Evaluation of safety of hypobaric decompressions and EVA from positions of probabilistic theory

Formation and subsequent evolution of gas bubbles in blood and tissues of subjects exposed to decompression are casual processes in their nature. Such character of bubbling processes in a body predetermines probabilistic character of decompression sickness (DCS) incidence in divers, aviators and astronauts. Our original probabilistic theory of decompression safety is based on stochastic models of these processes and on the concept of critical volume of a free gas phase in body tissues. From positions of this theory, the probability of DCS incidence during single-stage decompressions and during hypobaric decompressions under EVA in particular, is defined by the distribution of possible values of nucleation efficiency in "pain" tissues and by its critical significance depended on the parameters of a concrete decompression. In the present study the following is shown: 1) the dimensionless index of critical nucleation efficiency for "pain" body tissues is a more adequate index of decompression stress in comparison with Tissue Ratio, TR; 2) a priory the decompression under EVA performed according to the Russian protocol is more safe than decompression under EVA performed in accordance with the U.S. protocol; 3) the Russian space suit operated at a higher pressure and having a higher "rigidity" induces a stronger inhibition of mechanisms of cavitation and gas bubbles formation in tissues of a subject located in it, and by that provides a more considerable reduction of the DCS risk during real EVA performance.     

Solving Optimization Problems for the Flight Trajectories of a Spacecraft with a High-Thrust Jet Engine in Pulse Formulation for an Arbitrary Gravitational Field in a Vacuum

A mathematically well-posed technique is suggested to obtain first-order necessary conditions of local optimality for the problems of optimization to be solved in a pulse formulation for flight trajectories of a spacecraft with a high-thrust jet engine (HTJE) in an arbitrary gravitational field in vacuum. The technique is based on the Lagrange principle of derestriction for conditional extremum problems in a function space. It allows one to formalize an algorithm of change from the problems of optimization to a boundary-value problem for a system of ordinary differential equations in the case of any optimization problem for which the pulse formulation makes sense. In this work, such a change is made for the case of optimizing the flight trajectories of a spacecraft with a HTJE when terminal and intermediate conditions (like equalities, inequalities, and the terminal functional of minimization) are taken in a general form. As an example of the application of the suggested technique, we consider in this work, within the framework of a bounded circular three-point problem in pulse formulation, the problem of constructing the flight trajectories of a spacecraft with a HTJE through one or several libration points (including the case of going through all libration points) of the Earth–Moon system. The spacecraft is launched from a circular orbit of an Earth's artificial satellite and, upon passing through a point (or points) of libration, returns to the initial orbit. The expenditure of mass (characteristic velocity) is minimized at a restricted time of transfer.     

Modifying the atlas of low lunar orbits using inert tethers

For long enough tethers, the coupling of the attitude and orbital dynamics may show non-negligible effects in the orbital motion of a tethered satellite about a central body. In the case of fast rotating tethers the attitude remains constant, on average, up to second order effects. Besides, for a tether rotating in a plane parallel to the equatorial plane of the central body, the attitude–orbit coupling effect is formally equal to the perturbation of the Keplerian motion produced by the oblateness of the central body and, therefore, may have a stabilizing effect in the orbital dynamics. In the case of a tethered satellite in a low lunar orbit, it is demonstrated that feasible tether lengths can help in modifying the actual map of lunar frozen orbits.     

Optimal control of a spinning double-pyramid Earth-pointing tethered formation

The dynamics and control of a tethered satellite formation for Earth-pointing observation missions is considered. For most practical applications in Earth orbit, a tether formation must be spinning in order to maintain tension in the tethers. It is possible to obtain periodic spinning solutions for a triangular formation whose initial conditions are close to the orbit normal. However, these solutions contain significant deviations of the satellites on a sphere relative to the desired Earth-pointing configuration. To maintain a plane of satellites spinning normal to the orbit plane, it is necessary to utilize “anchors”. Such a configuration resembles a double-pyramid. In this paper, control of a double-pyramid tethered formation is studied. The equations of motion are derived in a floating orbital coordinate system for the general case of an elliptic reference orbit. The motion of the satellites is derived assuming inelastic tethers that can vary in length in a controlled manner. Cartesian coordinates in a rotating reference frame attached to the desired spin frame provide a simple means of expressing the equations of motion, together with a set of constraint equations for the tether tensions. Periodic optimal control theory is applied to the system to determine sets of controlled periodic trajectories by varying the lengths of all interconnecting tethers (nine in total), as well as retrieval and simple reconfiguration trajectories. A modal analysis of the system is also performed using a lumped mass representation of the tethers.     

Detour Strategies in Humans: Testing the Predictions of a Cognitive Map Model

In this paper, we test the predictions of a model developed by Voicu and Schmajuk (2002) in a paradigm that consists of placing an obstacle on a path between a start place and a goal after that path has been experienced by human participants several times. The model predicts that more experience with the path increases the likelihood of the participants performing a detour, e.g., circumventing the obstacle and resuming the original path, and decreases the probability of taking a shortcut to the goal. This prediction is tested in humans in a computed-simulated virtual environment. The experimental results agree with the prediction of the model for the case in which subjects have a limited view of the environment. In the case where they have an unrestricted view of the environment, they are more likely to move directly to the goal irrespective of the experience with the path between the two places.     

NEEMO 7 undersea mission

The NEEMO 7 mission was the seventh in a series of NASA-coordinated missions utilizing the Aquarius undersea habitat in Florida as a human space mission analog. The primary research focus of this mission was to evaluate telementoring and telerobotic surgery technologies as potential means to deliver medical care to astronauts during spaceflight. The NEEMO 7 crewmembers received minimal pre-mission training to perform selected medical and surgical procedures. These procedures included: (1) use of a portable ultrasound to locate and measure abdominal organs and structures in a crewmember subject; (2) use of a portable ultrasound to insert a small needle and drain into a fluid-filled cystic cavity in a simulated patient; (3) surgical repair of two arteries in a simulated patient; (4) cystoscopy and use of a ureteral basket to remove a renal stone in a simulated patient; and (5) laparoscopic cholecystectomy in a simulated patient. During the actual mission, the crewmembers performed the procedures without or with telementoring and telerobotic assistance from experts located in Hamilton, Ontario. The results of the NEEMO 7 medical experiments demonstrated that telehealth interventions rely heavily on a robust broadband, high data rate telecommunication link; that certain interventional procedures can be performed adequately by minimally trained individuals with telementoring assistance; and that prior clinical experience does not always correlate with better procedural performance. As space missions become longer in duration and take place further from Earth, enhancement of medical care capability and expertise will be required. The kinds of medical technologies demonstrated during the NEEMO 7 mission may play a significant role in enabling the human exploration of space beyond low earth orbit, particularly to destinations such as the Moon and Mars.     

Optimum parameters of a gravitational satellite-stabilizer system

Dynamics of a satellite-stabilizer system is studied. It is supposed that there is a viscous friction in a hinge connecting two bodies, but there is no elasticity. The attitude motion in a plane of circular orbit is considered, and parameters are determined, at which natural oscillations near a stable equilibrium position in the orbital coordinate system are damped out most rapidly. The rate of transient processes is estimated by a value of the degree of stability of linearized equations of motion. The optimization of the degree of stability is sequentially performed in dimensionless damping coefficient (the first stage) and in inertial system parameters (the second stage). The result of the first stage is the partition of system parameter space into the regions, in each of which the maximum of the degree of stability is reached on a particular configuration of roots of the characteristic equation. It is shown at the second stage that the global maximum is reached at two points of parameter space, where one of system bodies degenerates into a plate, and the characteristic equation has four equal real roots.     

The Effect of Dissipative Moments Caused by Liquid Body Viscosity on the Rotation Stability of a Space Object

The influence of dissipative forces in a viscous liquid that completely fills the cavities of a space object executing a rotational motion is analyzed. The Navier–Stokes equations are solved by expanding them into a series in terms of eigenfunctions of the boundary value problem on involving the resting liquid in rotation around the longitudinal axis of a cavity. The analytical solutions for coaxial cylindrical and concentric spherical cavities are obtained, in particular, for a straight circular cylinder and a sphere. The stability of the single-axis orientation of a space object filled with a viscous liquid is investigated. The dependences of rotation decay processes and drifts of the space object's longitudinal axis from a given direction are shown on the plane of constructive parameters.     

The Use of Quaternions in the Optimal Control Problems of Motion of the Center of Mass of a Spacecraft in a Newtonian Gravitational Field: II

The problem of a rendezvous in the central Newtonian gravitational field is considered for a controlled spacecraft and an uncontrollable spacecraft moving along an elliptic Keplerian orbit. For solving the problem, two variants of the equations of motion for the spacecraft center of mass are used, written in rotating coordinate systems and using quaternion variables to describe the orientations of these coordinate systems. In the first variant of the equations of motion a quaternion variable characterizes the orientation of an instantaneous orbit of the spacecraft and the spacecraft location in the orbit, while in the second variant it characterizes the orientation of the plane of the spacecraft instantaneous orbit and the location of a generalized pericenter in the orbit. The quaternion variable used in the second variant of the equations of motion is a quaternion osculating element of the spacecraft orbit. The problem of a rendezvous of two spacecraft is formulated as a problem of optimal control by the motion of the center of mass of a controlled spacecraft with a movable right end of the trajectory, and it is solved on the basis of Pontryagin's maximum principle.     

Two-craft tether formation relative equilibria about circular orbits and libration points

The relative equilibria of a two spacecraft tether formation connected by line-of-sight elastic forces moving in the context of a restricted two-body system and a circularly restricted three-body system are investigated. For a two spacecraft formation moving in a central gravitational field, a common assumption is that the center of the circular orbit is located at the primary mass and the center of mass of the formation orbits around the primary in a great-circle orbit. The relative equilibrium is called great-circle if the center of mass of the formation moves on the plane with the center of the gravitational field residing on it; otherwise, it is called a nongreat-circle orbit. Previous research shows that nongreat-circle equilibria in low Earth orbits exhibit a deflection of about a degree from the great-circle equilibria when spacecraft with unequal masses are separated by 350 km. This paper studies these equilibria (radial, along-track and orbit-normal in circular Earth orbit and Earth–Moon Libration points) for a range of inter-craft distances and semi-major axes of the formation center of mass. In the context of a two-spacecraft Coulomb formation with separation distances on the order of dozens of meters, this paper shows that the equilibria deflections are negligible (less than 10^?6°) even for very heterogeneous mass distributions. Furthermore, the nongreat-circle equilibria conditions for a two spacecraft tether structure at the Lagrangian libration points are developed.     

用动态分析法表征复合推进剂偶联剂的作用效果

研究了偶联剂对复合推进剂动态力学损耗的影响。建立了一种动态力学分析方法，即通过建立过渡相模型和引入表征因子Ａ，分别在ＨＴＰＢ和聚醚两种体系的复合推进中评价了偶联剂的作用效果。结果表明，天征因子Ａ值越低，偶联剂在该温度范围内的作用效果越好，该结论为表征复合推进剂关剂的作用效果提供了一种新的方法。