MEDES clinical research facility as a tool to prepare ISSA space flights

This new multi-disciplinary medical experimentation center provides the ideal scientific, medical and technical environment required for research programs and to prepare international space station Alpha (ISSA) missions, where space and healthcare industries can share their expertise. Different models are available to simulate space flight effects (bed-rest, confinement,...). This is of particular interest for research in Human psychology, physiology, physiopathology and ergonomics, validation of biomedical materials and procedures, testing of drugs, and other healthcare related products. This clinical research facility (CRF) provides valuable services in various fields of Human research requiring healthy volunteers. CRF is widely accessible to national and international, scientific, medical and industrial organisations. Furthermore, users have at their disposal the multi-disciplinary skills of MEDES staff and all MEDES partners on a single site.     

From space medicine to preventive and personalized health care on earth

The experience of human spaceflight has taught us that aging can be modulated, accelerated and decelerated. This is also confirmed by a number of experiments on animal models. However in order to be effective in managing aging and maintaining quality of life, a new approach needs to be adopted, one that many today call functional medicine or anti-aging medicine that in its essence is very similar to the medical approach provided to the astronauts by space agencies. Space medicine therefore can become a vehicle for the promotion of a new way of doing medicine on Earth.     

Telemedicine for the international space station

The medical care for the integrated crew of the International Space Station (ISS) will require close co-operation between the partner agencies in the areas of selection, medical surveillance, countermeasures, and handling of acute medical problems. Based on a commonly accepted policy of shared care and responsibilities medical guidelines, procedures, and standards for medical data and communication need to be harmonised under the responsibility of the Multilateral Medical Operations Panel (MMOP). A supporting telemedical network connecting the partners on an organisational and technical level will facilitate the harmonisation process and provide new tools for effective co-operation between medical professionals. Earth bound projects with similar application areas can profit from and contribute to this development and need to be considered for efficient implementation and exploitation.     

Development of Skylab medical equipment and flight preparations

The purpose of this report is to provide an introduction and overview of the Skylab medical program. Some of the more important medical systems and equipment provided for crew sustenance are described. The major inflight medical experiments are reviewed, and the test programs are discussed. The medical operations procedures and the techniques used to monitor crew health are reviewed to provide an understanding of the medical management of this complex mission.     

基于PKI与智能卡的防伪电子病历

随着医疗系统的发展和医疗体制改革的深入 ,医院信息系统向电子病历的目标发展显得日益迫切。文中分析了电子病历发展中存在的主要困难 ,对其中的信息和通信安全问题进行了研究。在此基础上 ,结合 PKI与智能卡技术的特点 ,提出了一种有效的电子病历防伪方案 ,并进行了具体实现     

Medical and surgical applications of space biosensor technology

Researchers in space life sciences are rapidly approaching a technology impasse. Many of the critical questions on the impact of spaceflight on living systems simply cannot be answered with the limited available technologies. Research subjects, particularly small animal models like the rat, must be allowed to function relatively untended and unrestrained for long periods to fully reflect the impact of microgravity and spaceflight on their behavior and physiology. These requirements preclude the use of present hard-wired instrumentation techniques and limited data acquisition systems. Implantable sensors and miniaturized biotelemetry are the only means of capturing the fundamental and critical data. This same biosensor and biotelemetry technology has direct application to Earth-based medicine and surgery. Continuous, on-line data acquisition and improved measurement capabilities combined with the ease and flexibility offered by automated, wireless, and portable instruments and data systems, should provide a boon to the health care industry. Playing a key role in this technology revolution is the Sensors 2000! (S2K!) Program at NASA Ames Research Center. S2K!, in collaboration with space life sciences researchers and managers, provides an integrated capability for sensor technology development and applications, including advanced biosensor technology development, spaceflight hardware development, and technology transfer and commercialization. S2K! is presently collaborating on several spaceflight projects with dual-use medical applications. One prime example is a collaboration with the Fetal Treatment Center (FTC) at the University of California at San Francisco. The goal is to develop and apply implantable chemical sensor and biotelemetry technology to continuously monitor fetal patients during extra-uterine surgery, replacement into the womb, through birth and beyond. Once validated for ground use, the method will be transitioned to spaceflight applications to remotely monitor key biochemical parameters in flight animals. Successful application of NASA implantable biosensor and biotelemetry technologies should accelerate the advancement of this and other modern medical procedures while furthering the exploration of life in space.     

Medical concerns for exploration-class missions

The Space Exploration Initiative will challenge life scientists with a diverse set of crew medical risks. The varied sources of this cumulative risk are identified and briefly discussed in terms of risk assessment and preliminary plans for risk management. The roles of Space Station Freedom and other flight programs are discussed in the context of exploration medical objectives; and the significant differences between Space Station era (second generation) and exploration medical support systems (third generation) are reviewed.     

Some approaches to medical support for Martian expedition

Medical support in a Martian expedition will be within the scope of crew responsibilities and maximally autonomous. Requirements to the system of diagnostics in this mission include considerable use of means and methods of visualization of the main physiological parameters, telemedicine, broad usage of biochemical analyses (including "dry" chemistry), computerized collection, measurement, analysis and storage of medical information. The countermeasure system will be based on objective methods of crew fitness and working ability evaluation, individual selection of training regimens, and intensive use of computer controlled training. Implementation of the above principles implies modernization and refinement of the countermeasures currently used by space crews of long-term missions (LTM), and increases of the assortment of active and passive training devices, among them a short-arm centrifuge. The system of medical care with the functions of prevention, clinical diagnostics and timely treatment will be autonomous, too. The general requirements to medical care during the future mission are the following: availability of conditions and means for autonomous urgent and special medical aid and treatment of the most possible states and diseases, "a hospital", and assignment to the crew of one or two doctors. To ensure independence of medical support and medical care in an expedition to Mars an automated expert system needs to be designed and constructed to control the medical situation as a whole.     

Astromedicine and astrolaw: Emerging issues for advanced missions beyond Earth orbit

It is generally agreed within the scientific community that provision of appropriate medical facilities and administration of quality health care to astronauts are of great importance. However, for the more complex and remote missions envisaged for the future, issues of liability, responsibility and damage relating to medical practice may take on a greater significance and will need to be addressed. The author briefly reviews potential issues which may arise in the context of medical emergencies, crew autonomy and environmentally altered physiological status which characterize some projected advanced space missions and argues that the law of outer space will need to be expanded to take account of them.     

The basic health care system for the lunar base crew

A plan of the health care system for the crew on the lunar base is described in this study. The health care system consists of two subsystems. The first is the daily health care system. The system contains health care menus, similar to those on Earth, and some biochemical and ordinary medical examinations. The second system is a periodic medical inspection for the crew's bones and the determination of natural radioisotopes in the body. These care systems are automatically treated with the examination and data filing. Usually these examinations are carried out without the presence of a medical doctor. Examinations and files of the whole results are controlled by a computer. The daily results of examinations are compared with data in the file. If any abnormal values are found in the results, an appropriate message is sent advising whether he must receive an in-depth examination by a medical doctor, or be reexamined by the same submenu. The automatic health care system also records transactions with the life support monitoring system.     

Life science research in space brings health on Earth

Leading scientists and physicians review groundbreaking research that is leading the way to better health care for astronauts and new treatments for medical problems on Earth. This research includes the development and testing of a new Ventricular Assist Device for patients with heart failure awaiting heart transplantation; advancements in telemedicine that bring medical care to remote areas on Earth and aid in the diagnosis and treatment of illness during space flight; advanced technologies, such as a miniature mass spectrometer, cardiac ultrasound equipment, bone imaging, non-invasive High-Intensity Focused Ultrasound, non-invasive techniques for blood and tissue chemistry measurements; and advances in the treatment of spinal cord injuries.     

Earth benefits from space life sciences

Contributions of space exploration which are widely recognized are those dealing with the impact of space technology on public health and medical services in both urban and remote rural areas. Telecommunications, image enhancement, 3-dimensional image reconstructions, miniaturization, automation, and data analysis, have transformed the delivery of medical care and have brought about a new impetus to the field of biomedicine. Many areas of medical care and biological research have been affected. These include technological breakthroughs in such areas as: (1) diagnosis, treatment, and prevention of cardiovascular diseases, (2) new approaches to the understanding of osteoporosis, (3) early detection of genetic birth defects, (4) emergency medical care, and (5) treatment of chronic metabolic disorders. These are but a few examples where technology originally developed to support space medicine or space research has been applied to solving medical and health care delivery problems on Earth.     

塞式喷管发动机的性能预示

采用理论分析的方法并结合塞式喷管的结构特点，建立塞式喷管壁面的的压力分布模型，对全长型、截短型以及考虑底部推力、底部二次流等情况下的塞式喷管发动机进行了性能预示，并同试验结果进行了对比分析。分析结果表明，塞式喷管发动机的性能预示结果同试验结果吻合较好，验证了预示模型的可行性，但是在某些工作压比下，预测值与试验值之间还有一定程度的差异，塞式喷管发动机的性能预示模型还有待进一步的完善。     

Review of basic medical results of the Salyut-7--Soyuz-T 8-month manned flight.

This paper presents the results of medical investigations performed in the Salyut-7 8-month mission in which a professional physician took part. The paper contains anthropometric measurements, results of investigating the vestibular function, cardiovascular function at rest and in response to multi-step tests (with emphasis on echocardiographic measurements), metabolic parameters and hormonal status. It also discusses medical aspects of the extravehicular activity. The medical investigations, although some new methods were applied, provided the continuity of methodical approaches and data accumulated in previous missions.     

卫星编队飞行星间相对运动

为分析编队卫星不同模型间的差异，分别根据动力学和运动学推导了星间相对运动的非线性、线性和相对轨道根数三种模型。以非线性相对运动模型为参考，在相同初始条件下比较各模型的位置误差。仿真结果表明：中心星在圆轨道或近圆轨道上运动时，三个模型结果相差较大。增大中心星轨道偏心率，可减小其位置误差。     

Nonisotropic turbulence in swirling flows

Recent experimental, inverse and prediction studies have disputed isotropy assumptions for turbulent swirling flows. To cater for the simulation (and hence solution) of these flows, simple turbulence models may be modified or more advanced models developed. This paper reviews recent work in this area, clarifies the entent of nonisotropy and recommends suitable turbulence models to effect closure of the governing Reynolds equations.     

公费医疗经费管理及信息分析系统

公费医疗经费管理及信息分析系统是应廊坊市卫生局的要求开发的。本系统以FOXPRO作开发平台，实现了用户提出的基本数据录入及修改、医疗经费核销与拨付、数据自动追加与核减、自动计算平均值及合计值、自动提供分析结果、浏览查询显示分析数据、打印分析总表及简化简化分析表、数据备份及恢复等功能。     

高精度陀螺加速度表的误差模型探讨

在全面考虑影响陀螺加速度表的误差因素的基础上,建立了陀螺加速度表的误差模型。该误差模型包括静态误差模型、动态误差模型和混合误差模型三部分。陀螺加速度表的误差模型的建立对实现有效的误差补偿和可靠地提高惯性系统实用精度提供理论依据。     

The telemedicine frontier: going the extra mile

Telemedicine has the potential to have a greater impact on the future of medicine than any other modality and will profoundly alter the medical landscape of the twenty-first century. In the most remote areas, it can bring high-quality health care where none is now available. In global health care, it can enhance and standardize the quality of medical care, including developing countries. In the realm of space flight, it can provide a lifeline to medical expertise and monitoring. Through its mobility, it can provide urgently needed health care in instances of natural disaster. However, a number of challenges exist in its coordination and implementation on a global scale, specifically in the international and remote disaster scenarios. In the area of spaceflight, telemedicine capability will remain a consultation/information ‘lifeline’, but additional onboard medical capability and expertise will become crucial complements as missions become more advanced and remote from Earth.     

Experiments on the quick-relief medical communications via the Japan's domestic communication satellite CS-2 for the case of disasters and emergencies.

Experiments on the quick-relief medical communications via the CS-2 satellite were carried out by using two types of 30/20 GHz small transportable earth stations whose antenna diameters are 1 and 2 m. As the terminal equipments, FM-SCPC systems with a one-telephone-equivalent channel were prepared for the transmission of voice, color freezed picture (9.6 kbps), supersonic echo signal and heart sound from a electrocardiograph. Signals from various medical equipments were transmitted by an FM-SCPC system from Simizu harbour (1 m station) to Tokyo transportable station (2 m), assuming that a person was injured in the ship and the ship came alongside the pier. Transmitted materials are mainly various kinds of pictures of affected parts, X-ray films and electrocardiograph with breathing sounds. It was found possible to send various medical information mentioned above via CS-2 by the 30/20 GHz simple communication systems with one-telephone-equivalent channel. Doctors suggested it would be possible to judge very well about the patients' emergency conditions and to give quick consult with inevitable treatment procedures for them. However, a few problems were found in the Hi-Fi reproduction of original colors and in the transmission of heart sounds in the very low frequency band less than 300 Hz.