NASA spinoffs to bioengineering and medicine

Through the active transfer of technology, the National Aeronautics and Space Administration (NASA) Technology Utilization (TU) Program assists private companies, associations, and government agencies to make effective use of NASA's technological resources to improve U.S. economic competitiveness and to provide societal benefit. Aerospace technology from areas such as digital image processing, space medicine and biology, microelectronics, optics and electrooptics, and ultrasonic imaging have found many secondary applications in medicine. Examples of technology spinoffs are briefly discussed to illustrate the benefits realized through adaptation of aerospace technology to solve health care problems. Successful implementation of new technologies increasingly requires the collaboration of industry, universities, and government, and the TU Program serves as the liaison to establish such collaborations with NASA. NASA technology is an important resource to support the development of new medical products and techniques that will further advance the quality of health care available in the U.S. and worldwide.     

Is space an environment?

Expanding the human sphere of influence beyond Earth presents philosophical questions that also have important practical applications. Do we need to worry about the moral implications of our actions in the vastness of space? What kind of explorers will we be - and what kind of explorers should we be? The answers to these basic questions depend greatly on what moral status is assigned to space; how it is conceptualized. This article sets forth arguments both for and against considering space as an environment, that is, as a place deserving of ethical treatment in the same way that terrestrial environments are valued and respected in environmental ethics. It sketches some answers to how space exploration could meet high ethical standards and puts forward the notion of environmental ‘virtue ethics’.     

On the contribution of space medicine in the public health care

With the beginning of space era, a new branch of medicine has arisen and has been developing along with human exploration of outer space. And even though space medicine mainly faces the same problems as traditional medicine--cosmonauts health care and their high efficiency--this branch, has its own features, associated with the unusual factors of space flight, of which weightlessness is the major one. During the development of manned cosmonautics (duration of a human stay in space has reached already 438 days), methods of cosmonauts medical support and monitoring of their condition have been developed, knowledge of human possibilities and methods of process of organism adaptation to various and frequently severe conditions of external environment have increased. All this led to the fact that nowadays space medicine can become useful for improvement of human health care not only in space but also on the Earth. Moreover, the problem of implementation of cosmonautics achievements, and in particular of space medicine, in practice of public health care presents one of the most important issues concerning human health care. It is also connected with public opinion which is more and more concerned about the efficiency of significant expenses on space activities, especially lately. People often are set by the questions: what has space given, what fruits has space research provided to mankind, which results of this research can be used on the Earth already today for improvement of their life, for discussion of many difficult earthly problems? In terms of using cosmonautics possibilities, its achievements for health care and treatment, it is possible to define a few branches, in which purposeful studies are carried out.     

IPv6在3G卫星通信系统中的发展模式探讨

面对地面3G演进和NGN（Next Generation Network）的发展趋势,以空间段为基础的3G卫星通信系统与技术应该扮演怎样的重要角色、如何进一步发展,已成为一个紧迫的研究课题。文章在分析NGN对于卫星通信发展影响的基础上,介绍了目前IPv6技术的空间应用以及3G业务在卫星中的应用模式,并对IPv6技术在3G卫星通信系统中的发展模式进行了探讨。     

Space, ethics and society. A CMES study

Ethical issues have for long been limited to the fields of medicine and biotechnology, whereas to-day such matters encompass a growing number of engineering activities. 21^st century citizens are more equiring about technoscientific claims and accomplishments. Has their impact on society and the ecological environment been measured and quantified? With all this accumulated knowledge and progress do they have the ability and means to resolve these self-created difficulties? Or will a totally new approach have to be sought? The debates include space activity not only because of the public funding needed but also because of the possible consequences on humans as well as the terrestrial, orbital or outer environment. Since the fall of 1998, CNES has undertaken the study of the role played by space activities in to-day's society and that of the future, seeking to clarify the objectives of the former with the expectations of the latter, and how they converge. The purpose of this study is to determine precisely the ethical responsibility of the space agencies and to pursue more sociological and philosophical research on the ethical scope of space activities.     

Advanced thin-film materials processing in the ultra-vacuum of space

The utilization of the vacuum of space for thin-film materials development has been pioneered by the Wake Shield Facility (WSF) program. The WSF is a 4 m diameter disc-shaped free-flying platform designed to generate an ultra-vacuum in low earth orbit (LEO) space, and to utilize that ultra-vacuum for the fabrication of thin-film materials by epitaxial growth. In the three flights of WSF, high-quality GaAs-based epitaxial thin films were grown, vacuum quality was assessed, and cooperative experiments were activated. The promising results on high-purity film growth indicate future benefits of thin-film materials fabrication in LEO for terrestrial applications in high-performance electronic devices.     

超导核磁共振技术在航天员生命保障中的应用前景探究

长期空间飞行会对航天员的身心健康造成一定的不利影响,开展航天员生命保障的研究是非常必要的。核磁共振技术是疾病检查诊断的重要手段,同样在航天员生命保障医疗中将发挥重要的作用。文章结合国内外相关研究进展以及航天员选拔、训练和航天员医监医保的相关知识,探究了超导核磁共振技术在航天员生命保障中的应用前景。     

An extensive phase space for the potential martian biosphere

We present a comprehensive model of martian pressure-temperature (P-T) phase space and compare it with that of Earth. Martian P-T conditions compatible with liquid water extend to a depth of ～310?km. We use our phase space model of Mars and of terrestrial life to estimate the depths and extent of the water on Mars that is habitable for terrestrial life. We find an extensive overlap between inhabited terrestrial phase space and martian phase space. The lower martian surface temperatures and shallower martian geotherm suggest that, if there is a hot deep biosphere on Mars, it could extend 7 times deeper than the ～5?km depth of the hot deep terrestrial biosphere in the crust inhabited by hyperthermophilic chemolithotrophs. This corresponds to ～3.2% of the volume of present-day Mars being potentially habitable for terrestrial-like life.     

Reliability analysis and utilization of PEMs in space application

More and more plastic encapsulated microcircuits (PEMs) are used in space missions to achieve high performance. Since PEMs are designed for use in terrestrial operating conditions, the successful usage of PEMs in space harsh environment is closely related to reliability issues, which should be considered firstly. However, there is no ready-made methodology for PEMs in space applications. This paper discusses the reliability for the usage of PEMs in space. This reliability analysis can be divided into five categories: radiation test, radiation hardness, screening test, reliability calculation and reliability assessment. One case study is also presented to illuminate the details of the process, in which a PEM part is used in a joint space program Double-Star Project between the European Space Agency (ESA) and China. The influence of environmental constrains including radiation, humidity, temperature and mechanics on the PEM part has been considered. Both Double-Star Project satellites are still running well in space now.     

Potential markets for application of space medicine achievements

The Institute of Biomedical Problems (IBMP) is the lead institution of the Russian Federation in the area of space biology and medicine. It has successfully implemented a set of innovation-based activities and projects to develop and introduce promising space products and technologies into the practices of Earth health care.     

25-Year overview: Safety and rescue symposia—Have they made a difference?

The stepping stones are traced from the birth of the IAA Committee on Space Rescue to the present day, 25 years later. The scope of the symposium was extended, successively, from that of space rescue to safety and rescue, and from crew rescue and spacecraft retrieval following Earth-surface touchdown to worldwide distress and disaster response, with benchmarks made on bringing to fruition satellite-aided search and rescue responding to terrestrial distress (COSPAS/SARSAT) and to space applications for disaster response.

In later years, a symposium session addressing space activities' impact on environment was initiated, with a principal focus on man-made space debris.

In 1991, a subcommittee on quality and an Ad Hoc Expert Group on space debris were established.

Its twenty-fifth-year contributions and influence are evident in the committee's organizational involvement across the IAA/IAF/COSPAR sessions at the 1992 World Space Congress.     

Space life and biomedical sciences in support of the global exploration roadmap and societal development

The human exploration of space is pushing the boundaries of what is technically feasible. The space industry is preparing for the New Space era, the momentum for which will emanate from the commercial human spaceflight sector, and will be buttressed by international solar system exploration endeavours. With many distinctive technical challenges to be overcome, human spaceflight requires that numerous biological and physical systems be examined under exceptional circumstances for progress to be made. To effectively tackle such an undertaking significant intra- and international coordination and collaboration is required. Space life and biomedical science research and development (R & D) will support the Global Exploration Roadmap (GER) by enabling humans to ‘endure’ the extreme activity that is long duration human spaceflight. In so doing the field will discover solutions to some of our most difficult human health issues, and as a consequence benefit society as a whole. This space-specific R&D will drive a significant amount of terrestrial biomedical research and as a result the international community will not only gain benefits in the form of improved healthcare in space and on Earth, but also through the growth of its science base and industry.     

MOA2—an R&D paradigm buster enabling space propulsion by commercial applications

More than 60 years after the late Nobel laureate Hannes Alfvén had published a letter stating that oscillating magnetic fields can accelerate ionised matter via magneto–hydrodynamic interactions in a wave like fashion, the technical implementation of Alfvén waves for propulsive purposes has been proposed, patented and examined for the first time by a group of inventors.Consequently improved since then, the name of the latest concept, relying on magneto-acoustic waves to accelerate electric conductive matter, is MOA²—Magnetic field Oscillating Amplified Accelerator. Based on computer simulations, which were undertaken to get a first estimate on the performance of the system, MOA² is a corrosion free and highly flexible propulsion system, whose performance parameters might easily be adapted in operation, by changing the mass flow and/or the power level. As such the system is capable of delivering a maximum specific impulse of 13116 s (12.87 mN) at a power level of 11.16 kW, using Xe as propellant, but can also be attuned to provide a thrust of 236.5 mN (2411 s) at 6.15 kW of power. First tests—that are further described in this paper—have been conducted successfully with a 400 W prototype system at an ambient pressure of 0.20 Pa, delivered 9.24 mN of thrust at 1472 s I_SP, thereby underlining the feasibility of the concept.Based on these results, space propulsion is expected to be a prime application for MOA²—a claim that is supported by numerous applications such as Solar and/or Nuclear Electric Propulsion or even as an ‘afterburner system’ for Nuclear Thermal Propulsion. However, MOA² has so far seen most of its R&D impetus from terrestrial applications, like coating, semiconductor implantation and manufacturing as well as steel cutting. Based on this observation, MOA² resembles an R&D paradigm buster, as it is the first space propulsion system, whose R&D is driven primarily by its terrestrial applications. Different terrestrial applications exist, but the most successful scenarios so far revolve around MOA²'s unique features with respect to high throughput/low target temperature coatings on sensitive materials. In combination with its intrinsic high flexibility, MOA² is highly suited for a common space-terrestrial application research and utilisation strategy.This paper presents the recent developments of the MOA² R&D activities at Q₂ Technologie(s), the company in Vienna, Austria, which has been set up to further develop and test the magneto-acoustic wave technology and its applications.     

Inflection points in the development of energy in space

Basing his comments around a report on the Space Power Systems 1997 conference, ‘Energy and Space for Humanity’, held in Montreal, 24-28 August 1997, Richard Boudreault describes the progress made in getting the concept of power from space accepted by the terrestrial utilities. Increasing worries about the sustainability of current power sources together with deregulation of power distribution make space power more attractive. However, the high cost of access to space is a barrier, though this is starting to fall.     

Ad hoc wireless sensor networks for exploration of Solar-system bodies

In this work, we evaluate the exploration of the Solar system by ad hoc wireless sensor networks (WSN), i.e., networks where all nodes (either moving or stationary) can both provide and relay data. The two aspects of self-organization and localization are the major challenges to achieve a reliable network for a variety of missions. We point out the diversity of environmental and operational constrains that WSN used for space exploration would face.We evaluate two groups of scenarios consisting in static or moving sensing nodes that can be either located on the ground or in the atmosphere of a Solar-system object. These scenarios enable collecting data simultaneously over a large surface or volume.We consider physical and chemical sensing of the atmosphere, surface and soil using such networks. Emerging technologies such as nodes localization techniques are reviewed. Finally, we compare the specific requirements of WSN for space exploration with those of WSN designed for terrestrial applications.     

Intuitive ultrasonography for autonomous medical care in limited-resource environments

Management of health problems in limited resource environments, including spaceflight, faces challenges in both available equipment and personnel. The medical support for spaceflight outside Low Earth Orbit is still being defined; ultrasound (US) imaging is a candidate since trials on the International Space Station (ISS) prove that this highly informative modality performs very well in spaceflight. Considering existing estimates, authors find that US could be useful in most potential medical problems, as a powerful factor to mitigate risks and protect mission. Using outcome-oriented approach, an intuitive and adaptive US image catalog is being developed that can couple with just-in-time training methods already in use, to allow non-expert crew to autonomously acquire and interpret US data for research or diagnosis.The first objective of this work is to summarize the experience in providing imaging expertise from a central location in real time, enabling data collection by a minimally trained operator onsite. In previous investigations, just-in-time training was combined with real-time expert guidance to allow non-physician astronauts to perform over 80 h of complex US examinations on ISS, including abdominal, cardiovascular, ocular, musculoskeletal, dental/sinus, and thoracic exams. The analysis of these events shows that non-physician crew-members, after minimal training, can perform complex, quality US examinations. These training and guidance methods were also adapted for terrestrial use in professional sporting venues, the Olympic Games, and for austere locations including Mt. Everest.The second objective is to introduce a new imaging support system under development that is based on a digital catalog of existing sample images, complete with image recognition and acquisition logic and technique, and interactive multimedia reference tools, to guide and support autonomous acquisition, and possibly interpretation, of images without real-time link with a human expert. In other words, we are attempting to replace, to the extent possible, expert guidance by guidance from a digital information resource. This is a next logical phase of the authors’ sustained effort to make US imaging available to sites lacking proper expertise. This effort will benefit NASA as the agency plans to develop future human exploration programs requiring increased medical autonomy. The new system will be readily adaptable to terrestrial medicine including emergency, rural, and military applications.     

A low-cost femtosatellite to enable distributed space missions

A new class of distributed space missions is emerging which requires hundreds to thousands of satellites for real-time, distributed, multi-point sensing to accomplish long-awaited remote sensing and science objectives. These missions, stymied by the lack of a low-cost mass-producible solution, can become reality by merging the concepts of distributed satellite systems and terrestrial wireless sensor networks. However, unlike terrestrial sensor nodes, space-based nodes must survive unique environmental hazards while undergoing complex orbital dynamics. A novel sub-kilogram very small satellite design is needed to meet these requirements. Sub-kilogram satellite concepts are developing elsewhere, such as traditional picosatellites and microengineered aerospace systems. Although viable technical solutions, these technologies currently come at a high cost due to their reliance on high-density technology or custom manufacturing processes. While evaluating these technologies, two untapped technology areas became evident that uniquely encompass low cost and mass producibility by leveraging existing commercial production techniques: satellite-on-a-chip (SpaceChip) and satellite-on-a-printed circuit board (PCBSat). This paper focuses on the design, build, and test results of a prototype PCBSat with a prototype unit cost less than $300. The paper concludes with mission applications and future direction.     

Earth benefits from space life sciences

Contributions of space exploration which are widely recognized are those dealing with the impact of space technology on public health and medical services in both urban and remote rural areas. Telecommunications, image enhancement, 3-dimensional image reconstructions, miniaturization, automation, and data analysis, have transformed the delivery of medical care and have brought about a new impetus to the field of biomedicine. Many areas of medical care and biological research have been affected. These include technological breakthroughs in such areas as: (1) diagnosis, treatment, and prevention of cardiovascular diseases, (2) new approaches to the understanding of osteoporosis, (3) early detection of genetic birth defects, (4) emergency medical care, and (5) treatment of chronic metabolic disorders. These are but a few examples where technology originally developed to support space medicine or space research has been applied to solving medical and health care delivery problems on Earth.     

Thoracic sonography for pneumothorax: the clinical evaluation of an operational space medicine spin-off

The recent interest in the use of ultrasound (US) to detect pneumothoraces after acute trauma in North America was initially driven by an operational space medicine concern. Astronauts aboard the International Space Station (ISS) are at risk for pneumothoraces, and US is the only potential medical imaging available. Pneumothoraces are common following trauma, and are a preventable cause of death, as most are treatable with relatively simple interventions. While pneumothoraces are optimally diagnosed clinically, they are more often inapparent even on supine chest radiographs (CXR) with recent series reporting a greater than 50% rate of occult pneumothoraces. In the course of basic scientific investigations in a conventional and parabolic flight laboratory, investigators familiarized themselves with the sonographic features of both pneumothoraces and normal pulmonary ventilation. By examining the visceral–parietal pleural interface (VPPI) with US, investigators became confident in diagnosing pneumothoraces. This knowledge was subsequently translated into practice at an American and a Canadian trauma center. The sonographic examination was found to be more accurate and sensitive than CXR (US 96% and 100% versus US 74% and 36%) in specific circumstances. Initial studies have also suggested that detecting the US features of pleural pulmonary ventilation in the left lung field may offer the ability to exclude serious endotracheal tube malpositions such as right mainstem and esophageal intubations. Applied thoracic US is an example of a clinically useful space medicine spin-off that is improving health care on earth.     

The telemedicine frontier: going the extra mile

Telemedicine has the potential to have a greater impact on the future of medicine than any other modality and will profoundly alter the medical landscape of the twenty-first century. In the most remote areas, it can bring high-quality health care where none is now available. In global health care, it can enhance and standardize the quality of medical care, including developing countries. In the realm of space flight, it can provide a lifeline to medical expertise and monitoring. Through its mobility, it can provide urgently needed health care in instances of natural disaster. However, a number of challenges exist in its coordination and implementation on a global scale, specifically in the international and remote disaster scenarios. In the area of spaceflight, telemedicine capability will remain a consultation/information ‘lifeline’, but additional onboard medical capability and expertise will become crucial complements as missions become more advanced and remote from Earth.