共查询到20条相似文献,搜索用时 0 毫秒
1.
This paper reviews existing hypotheses concerning the mechanisms of adaptation of the vestibular apparatus and related somatosensory systems to microgravity with reference to the flight data. Having in view theoretical concepts and experimental data accumulated in space flights, a conceptual model of the development of a funtional system responsible for the termination of vestibular dysfuntion and space motion sickness manifestations is presented. It is also shown that changes in the hormonal status during motion sickness induced by vestibular stimulation give evidence that endocrine regulation of certain functions can be involved in adaptive responses. 相似文献
2.
A Graybiel 《Acta Astronautica》1981,8(9-10):1015-1018
A substantial number of persons, around 75%, making their first transition into orbital flight will need to adapt to this unique environment. The two most powerful instruments in the prevention of space motion sickness reside in the selection process and in acquiring adaptation-prelaunch. Today, neither of these means is practical. One logical alternative is to administer preventative medication to all or none. One candidate drug is a high-potency transdermal therapeutic system (TTS)-scopolamine. This is marketed in the nature of a patch that is affixed to the skin behind the ear 12 hr before need and delivers scopolamine into the blood stream for three days. We are systematically evaluating all claims for its high potency and low side effects. We are also evaluating new antimotion sickness remedies and new combinations of homergic drugs. 相似文献
3.
One of the Skylab experiments dealt with motion sickness, comparing susceptibility in the workshop aloft with susceptibility preflight and postflight. Tests were conducted on and after mission-day 8 (MD 8) by which time the astronauts were adapted to working conditions. Stressful accelerations were generated by requiring the astronauts, with eyes covered, to execute standardized head movements (front, back, left, and right) while in a chair that could be rotated at angular velocities up to 30 rpm. The selected endpoint was either 150 discrete head movements or a very mild level of motion sickness. In all rotation experiments aloft, the five astronauts tested (astronaut 1 did not participate) were virtually symptom free, thus demonstrating lower susceptibility aloft than in preflight and postflight tests on the ground when symptoms were always elicited. Inasmuch as the eyes were covered and the canalicular stimuli were the same aloft as on the ground, it would appear that lifting the stimulus to the otolith organs due to gravity was an important factor in reducing susceptibility to motion sickness even though the transient stimuli generated under the test conditions were substantial and abnormal in pattern. Some of the astronauts experienced motion sickness under operational conditions aloft or after splashdown, but attention is centered chiefly on symptoms manifested in zero gravity. None of the Skylab-II crew (astronauts 1 to 3) was motion sick aloft. Astronaut 6 of the Skylab-III crew (astronauts 4 to 6) experienced motion sickness within an hour after transition into orbit; this constitutes the earliest such diagnosis on record under orbital flight conditions. The eliciting stimuli were associated with head and body movements, and astronaut 6 obtained relief by avoiding such movements and by one dose of the drug combination 1-scopolamine 0.35 mg + d-amphetamine 5.0 mg. All three astronauts of Skylab-III experienced motion sickness in the workshop where astronaut 6 was most susceptible and astronaut 4, least susceptible. The higher susceptibility of SL-III crewmen in the workshop, as compared with SL-II crewmen, may be attributable to the fact that they were based in the command module less than one-third as long as SL-II crewmen. The unnatural movements, often resembling acrobatics, permitted in the open spaces of the workshop revealed the great potentialities in weightlessness for generating complex interactions of abnormal or unusual vestibular and visual stimuli. Symptoms were controlled by body restraint and by drugs, but high susceptibility to motion sickness persisted for 3 days and probably much longer; restoration was complete on MD 7. From the foregoing statements it is clear that on and after MD 8 the susceptibility of SL-II and SL-III crewmen to motion sickness under experimental conditions was indistinguishable. The role played by the acquisition of adaptation effects prior to MD 8 is less clear and is a subject to be discussed. 相似文献
4.
This paper proposes a new goldfish model to predict pharmacodynamic/pharmacokinetic effects of drugs used to treat motion sickness administered in differing gravity loads. The assumption of these experiments is that the vestibular system is dominant in producing motion sickness and that the visual system is secondary or of small import in the production of motion sickness. Studies will evaluate the parameter of gravity and the contribution of vision to the role of the neurovestibular system in the initiation of motion sickness with and without pharmacologic agents. Promethazine will be studied first. A comparison of data obtained in different groups of goldfish will be done (normal vs. acutely and chronically bilaterally blinded vs. sham operated). Some fish will be bilaterally blinded 10 months prior to initiation of the experiment (designated the chronically bilaterally blinded group of goldfish) to evaluate the neuroplasticity of the nervous system and the associated return of neurovestibular function. Data will be obtained under differing gravity loads with and without a pharmacological agent for motion sickness. Experiments will differentiate pharmacological effects on vision vs. neurovestibular input to motion sickness. Comparison of data obtained in the normal fish and in acutely and chronically bilaterally blinded fish with those obtained in fish with intact and denervated otoliths will differentiate if the visual or neurovestibular system is dominant in response to altered gravity and/or drugs. Experiments will contribute to validation of the goldfish as a model for humans since plasticity of the central nervous system allows astronauts to adapt to the altered visual stimulus conditions of 0-g. Space motion sickness may occur until such an adaptation is achieved. 相似文献
5.
The European Union draft Code of Conduct for outer space activities is one of the primary international initiatives, that are currently active, to enhance the safety, security and sustainability of outer space activities. Although the spirit underlying the instrument is commonly shared by space-faring countries, substantial disagreement exists among States as to some of its core provisions. This article proposes that the Code of Conduct should make a clear distinction between commercial activities and military activities, and adopt more balanced measures on the restriction of military activities in outer space. 相似文献
6.
Space motion sickness has been estimated as affecting between 1/3 and 1/2 of all space flight participants. NASA has at the moment proposed a combination of promethazine and ephedrine (P/E) and one of scopolamine and dextroamphetamine (S/D), both given orally, as well as a transdermally applied scopolamine (TAS), as preventive and ameliorative measures. The reported double-blind study, tests the early phase actions and efficacy of the transdermal scopolamine (Transderm (TM)-V of ALZA Corporation) and compares these in detail to the oral medications. Motion sickness resistance was tested by standardized head movements while accelerating at 0.2 degree/sec2 to a maximum rotation of 240 degrees/sec, with an intermediate plateau of 10 min at 180 degrees/sec. To permit weighting motion sickness protection against other system influences, cardiovascular, psychological (subjective and objective), and visual parameter changes were documented for the three therapeutic modes. The relative impact of the various modalities on operational and experimental components of space missions is discussed. A comparison to intramuscularly administered promethazine (a backup therapeutic mode suggested for Space Shuttle use) is also included. 相似文献
7.
G. S. Zaslavskiy V. A. Stepan’yants A. G. Tuchin A. V. Pogodin E. N. Filippova A. I. Sheikhet 《Cosmic Research》2014,52(5):353-364
The results of refining the parameters of the Spektr-R spacecraft (RadioAstron project) motion after it was launched into the orbit of the Earth’s artificial satellite in July 2011 showed that, at the beginning of 2013, the condition of staying in the Earth’s shadow was violated. The duration of shading of the spacecraft exceeds the acceptable value (about 2 h). At the end of 2013 to the beginning of 2014, the ballistic lifetime of the spacecraft completed. Therefore, the question arose of how to correct the trajectory of the motion of the Spektr-R satellite using its onboard propulsion system. In this paper, the ballistic parameters that define the operation of onboard propulsion system when implementing the correction, and the ballistic characteristics of the orbital spacecraft motion before and after correction are presented. 相似文献
8.
Angular motion at atmospheric entry is studied in the paper for a spacecraft with a bi-harmonic moment characteristic. Special attention is given to the case when the spacecraft possesses two stable balanced positions, and, hence, it can oscillate in dense atmospheric layers in the ranges of small or large angles of attack. The averaged equations of spacecraft motion are derived, which allow one to increase the speed of calculations by several orders of magnitude. A real example is presented, which concerns a spacecraft specially designed for descending in the Martian atmosphere. 相似文献
9.
Attitude control techniques for the pointing and stabilization of very large, inherently flexible spacecraft systems are investigated. The attitude dynamics and control of a long, homogeneous flexible beam whose center of mass is assumed to follow a circular orbit is analyzed. In this study, first order effects of gravity-gradient are included, whereas external perturbations and related orbital station keeping maneuvers are neglected. A mathematical model which describes the system deflections within the orbital plane has been developed by treating the beam as having a maximum of three discretized mass particles connected by massless, elastic structural elements. The uncontrolled dynamics of this system are simulated and, in addition, the effects of the control devices are considered. The concept of distributed modal control, which provides a means for controlling a system mode independently of all other modes, is examined. The effect of varying the number of modes in the model as well as the number and location of the control devices are also considered. 相似文献
10.
11.
对橡胶制品喷霜的成因从配方设计、硫化工艺、模具、环境条件、氧化影响等方面进行了理论分析,并针对橡胶膜片表面喷霜现象进行了电镜扫描测试及机理分析研究。冷却温度对膜片表面喷霜影响试验表明,膜片制造工艺过程中膜片启模后,冷却温度控制在0~15℃可有效解决膜片表面喷霜问题。 相似文献
12.
A study of peculiarities of the motion of equatorial circular geosynchronous satellites is performed in the neighborhoods of unstable stationary points with longitudes of 165° and 345°. The maps of initial conditions are constructed on the phase plane “longitude of subsatellite point-semi-major axis of orbit” corresponding to various types of regular motions and to quasi-random solutions. The dimensions of zones of the quasi-random solutions are within the limits from decimal fractions of a degree to a few degrees (in longitude) and from hundreds of meters up to several kilometers (along the semi-major axis). 相似文献
13.
A Newton-type method is proposed to improve the accuracy of control for relative motion of two satellites in close formation. We assume that the deputy satellite is equipped with a passive attitude control system that provides one-axis stabilization, and one or two orbit control thrusters are installed along the stabilized axis. Previous studies show that it is possible to construct periodic relative trajectories both in case of passive magnetic and spin stabilization. However, the accuracy of the numerically obtained control is quite low due to modeling errors caused by linearization of the equations of relative motion. Therefore, a correction procedure is required to compensate for nonlinear effects. To this end we suggest a recently developed algorithm based on the Newton method for solving nonlinear systems with geometric constraints. Being implemented, this algorithm allows decreasing the modeling error by up to ten times. The previously found control and trajectory of the linearized system are used as initial approximations. 相似文献
14.
A. A. Zlenko 《Cosmic Research》2006,44(1):69-73
The stationary motions of a synchronous axisymmetric satellite are studied in the field of attraction by the Earth and a third body whose parameters are close to those of the Moon. Equations of motion are written in canonical variables that take into account the resonance character of the problem. The plots characterizing the dependence of the rotation parameters of the satellite relative to the center of mass on the elements of satellite’s translational motion are presented. A picture is given that represents the initial configuration of the system for implementing stationary motions. 相似文献
15.
D. V. Doronin 《Cosmic Research》2008,46(3):244-250
Based on the methods of the theory of optimum control of dynamic systems, as well as the methods of inverse problems of dynamics and the energy principle, a combined method is developed for control of the motion of a flying vehicle of the Aerospace plane type during the long flight in the atmosphere. The disturbed motion is considered under the conditions when there are constraints on the values of control actions and on functions of phase coordinates. 相似文献
16.
Translational-rotational motion of two viscoelastic planets in a gravitational force field is studied. The planets are modeled by homogeneous isotropic viscoelastic bodies. In their natural undeformed state each of the planets represents a sphere. We investigate a specific case when the planet’s centers of mass move in a fixed plane, the axis of rotation for each planet being directed along the normal to this plane. An equation describing the evolution of a slow angular variable (perihelion longitude) is derived. The observed displacement of the perihelion of Mercury is compared with the results obtained in the considered model problem about motion of two viscoelastic planets. Quite important is the fact that the planet of smaller mass (Mercury) moves not in a central Newtonian field of forces, but rather in the gravitational field of a rotating viscoelastic planet (Sun). 相似文献
17.
Yu. M. Zabolotnov 《Cosmic Research》2013,51(3):213-224
The laws of distribution of the space angle of attack are analyzed for a light descent capsule on the atmosphere’s conventional boundary and on the segment of motion in dense layers of the atmosphere until the moment of reaching the maximum velocity head. It is assumed that upon detachment from a base spacecraft the angular velocity components of the descent capsule represent independent random quantities distributed according to the normal law. The shape of the descent capsule is close to a body of revolution whose instantaneous aerodynamic characteristic has a sufficiently simple form (one stable and one unstable positions of static equilibrium). It is demonstrated that there is a possibility to approximate the distribution densities by well-known laws and by approximate functions constructed on the basis of simplified models. Evolution of the distribution laws at increasing mass-inertia asymmetry of the descent capsule is studied. 相似文献
18.
The paper reviews the research that has been undertaken to understand and quantify the disturbance effects of the astronaut's motion inside and outside the spacecraft on the vehicle's attitude and acceleratory environment. In early investigations, the dynamic interaction of astronauts, modeled as point masses, and the spacecraft, modelled as a rigid body, was analyzed. Through ground-based experiments and the modeling of astronaut-induced forces and moments as stochastic processes, it became possible to estimate the magnitude and energy content of the loads produced by the astronaut. The first experiment in space to measure the astronaut-induced disturbances was conducted on the Skylab orbital station. Loads generated while performing routine operations were measured on board the Space Shuttle in 1994 and on the space station Mir in 1996–1997. 相似文献
19.
A. P. Blinov 《Cosmic Research》2007,45(2):152-155
Numerous papers are devoted to studying the motion of a system (coupling) of two bodies in the Earth’s satellite orbit ([1–4] and others). The problem on the planar inertial motion of three bodies, coupled by a non-extensible weightless string having the form of an unfastened chain, is considered in the paper. Such a configuration can be represented, for example, by a system of two coupled spacecraft rotating around their common center of mass (in order to simulate the gravity force) in long-term space missions, when the third body (the lift) is located on a connecting cable. The bodies are considered to be the material points (particles). 相似文献
20.