Solar-flare neutrons and gamma rays

Calculations of neutron and gamma-ray production in solar flares are reviewed and compared with neutron and gamma-ray data from the 21 June 1980 and 3 June 1982 flares, as well as gamma-ray data from other flares. The implied charged-particle numbers and spectra are compared with interplanetary observations.     

Survival of irradiated mice treated with WR-151327, synthetic trehalose dicorynomycolate, or ofloxacin.

Spaceflight personnel need treatment options that would enhance survival from radiation and would not disrupt task performance. Doses of prophylactic or therapeutic agents known to induce significant short-term (30-day) survival with minimal behavioral (locomotor) changes were used for 180-day survival studies. In protection studies, groups of mice were treated with the phosphorothioate WR-151327 (200 mg/kg, 25% of the LD(10)) or the immunomodulator, synthetic trehalose dicorynomycolate (S-TDCM; 8 mg/kg), before lethal irradiation with reactor-generated fission neutrons and gamma-rays (n/gamma=1) or 60Co gamma-rays. In therapy studies, groups of mice received either S-TDCM, the antimicrobial ofloxacin, or S-TDCM plus ofloxacin after irradiation. For WR-151327 treated-mice, survival at 180 days for n/gamma=1 and gamma-irradiated mice was 90% and 92%, respectively; for S-TDCM (protection), 57% and 78%, respectively; for S-TDCM (therapy), 20% and 25%, respectively; for ofloxacin, 38% and 5%, respectively; for S-TDCM combined with ofloxacin, 30% and 30%, respectively; and for saline, 8% and 5%, respectively. Ofloxacin or combined ofloxacin and S-TDCM increased survival from the gram-negative bacterial sepsis that predominated in n/gamma=1 irradiated mice. The efficacies of the treatments depended on radiation quality, treatment agent and its mode of use, and microflora of the host.     

Radiation protection against early and late effects of ionizing irradiation by the prostaglandin inhibitor indomethacin.

Protective effects of indomethacin, a prototype prostaglandin-inhibiting agent, against early and late sequelae of radiation injury (after X-rays or gamma rays) in mice were investigated. The following tissues or organs were examined: hematopoietic tissue, esophagus, jejunum, colon, lung, hair follicles, and tissues involved in the development of radiation-induced leg contractures. In addition, the effect of indomethacin was tested against radiation-induced carcinogenesis. In all experiments, the radiation was delivered as a single dose. Indomethacin led to significant protection of hematopoietic tissue, by a factor of 1.3. There was also some protection against radiation-induced pneumonitis and against radiation-induced carcinogenesis (protection factor of 1.2). The other tissues tested showed no change in their radioresponse after being treated with indomethacin. Thus, indomethacin can act as a radioprotective agent against both early and late sequelae of radiation, but its effect is dependent on the tissue tested. This protection is smaller than that observed with WR-2721. However, indomethacin combined with WR-2721 produced a radioprotective effect greater than the radioprotection achieved by individual treatments.     

The radial distribution of gamma rays and cosmic rays in the outer Galaxy

The radial distribution of the high-energy (70 MeV-5 GeV) gamma-ray emissivity in the outer Milky Way is derived. The kinematics of HI are used to construct column-density maps in three galacto-centric distance ranges in the outer Galaxy. These maps are used in combination with COS-B gamma-ray data to determine gamma-ray emissivities in these distance ranges. A steep negative gradient of the emissivity for the 70 MeV-150 MeV energy range is found in the outer Galaxy. The emissivity for the 300 MeV-5 GeV range is found to be approximately constant (within 20%) and equal to the local value out to large (20 kpc) galacto-centric distances. These results imply a hardening of the gamma-ray spectrum with increrasing distance and for R > 16 kpc the spectrum is shown to be consistent with a π°-decay spectrum with the intensity expected from the local measurement of the cosmic-ray nuclei spectrum. The energy-dependent decrease is interpreted as a steep gradient in the cosmic-ray electron density and a near constancy of the nuclear component. The galactic origin of electrons with energies up to several hundreds of MeV is confirmed, while for cosmic-ray nuclei with energies of a few GeV either confinement in a large galactic halo or an extragalactic origin is suggested by the data.     

Absorbed dose of secondary neutrons from galactic cosmic rays inside the International Space Station.

In this paper, we present the results of Monte-Carlo simulations of the flux and energy spectra of neutrons generated as a result of galactic cosmic ray proton interactions with the material of International Space Station (ISS) inside Zvezda Service Module, the Airlock between Russian and USA segments and one of Russian Research Modules for a full configuration of ISS. Calculations were made for ISS orbit for the energy ranges <10 and >10 MeV for both maximum and minimum of solar activity. To test the accuracy of the calculations the same simulations were made for MIR orbital station and for CORONAS-I satellite and compared with the results of measurements. Calculated and measured fluxes are in reasonable agreement.     

Measurements and calculations of gamma rays from proton-irradiated thick targets

To help understand planetary gamma-ray spectra, the energies and intensities of gamma rays produced by energetic particles interacting in thick targets were simulated experimentally and numerically. Using the accelerator at RIKEN, thick targets of iron, granite, and gabbro were exposed to 180 or 210 MeV proton beam, and characteristic gamma rays emitted from the targets were measured by Ge detectors. The experimental results were compared with the values calculated by Geant4. The relative intensities of gamma-ray lines from the iron target in the experiment were consistent with those in the calculation within the error of ∼5%. As for stone targets, strong inconsistencies were observed. Further improvement in the calculation code and cross section files, as well as experimental resemblance to space missions are indispensable for gamma-ray spectroscopy.     

Uncertainties in estimates of the risks of late effects from space radiation.

Methods used to project risks in low-Earth orbit are of questionable merit for exploration missions because of the limited radiobiology data and knowledge of galactic cosmic ray (GCR) heavy ions, which causes estimates of the risk of late effects to be highly uncertain. Risk projections involve a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Using the linear-additivity model for radiation risks, we use Monte-Carlo sampling from subjective uncertainty distributions in each factor to obtain an estimate of the overall uncertainty in risk projections. The resulting methodology is applied to several human space exploration mission scenarios including a deep space outpost and Mars missions of duration of 360, 660, and 1000 days. The major results are the quantification of the uncertainties in current risk estimates, the identification of factors that dominate risk projection uncertainties, and the development of a method to quantify candidate approaches to reduce uncertainties or mitigate risks. The large uncertainties in GCR risk projections lead to probability distributions of risk that mask any potential risk reduction using the "optimization" of shielding materials or configurations. In contrast, the design of shielding optimization approaches for solar particle events and trapped protons can be made at this time and promising technologies can be shown to have merit using our approach. The methods used also make it possible to express risk management objectives in terms of quantitative metrics, e.g., the number of days in space without exceeding a given risk level within well-defined confidence limits.     

Observations and predictions of secondary neutrons on Space Shuttle and aircraft.

The Cosmic Radiation Effects and Activation Monitor has flown on six Shuttle flights between September 1991 and February 1995 covering the full range of inclinations as well as altitudes between 220 and 570 km, while a version has flown at supersonic altitudes on Concorde between 1988 and 1992 and at subsonic altitudes on a SAS Boeing 767 between May and August 1993. The Shuttle flights have included passive packages in addition to the active cosmic ray monitor which comprises an array of pin diodes. These are positioned at a number of locations to investigate the influence of shielding and local materials. Use of both metal activation foils and scintillator crystals enables neutron fluences to be inferred from the induced radioactivity which is observed on return to Earth. Supporting radiation transport calculations are performed to predict secondary neutron spectra and the energy deposition due to nuclear reactions in silicon pin diodes and the induced radioactivity in the various scintillator crystals. The wide variety of orbital and atmospheric locations enables investigation of the influence of shielding on cosmic ray, trapped proton and solar flare proton spectra.     

Flux upper limits of diffuse TeV gamma rays from the Galactic plane using the effective area of the Tibet-II and -III arrays

We obtained new upper limits on the diffuse gamma rays from the inner Galactic (IG) and outer Galactic (OG) planes in 3–10 TeV region, using the Tibet air shower data and new Monte Carlo simulation results. A difference of the effective area of the air-shower array for observing gamma rays and cosmic rays was carefully taken into account in this analysis, resulting in that the flux upper limits of the diffuse TeV gamma rays were reduced by factors of 4.0–3.7 for 3–10 TeV than those in our previous results (Amenomori, M., Ayabe, S., Cui, S.W., et al. Observation of multi-TeV diffuse gamma rays from the Galactic plane with the Tibet air shower array. Astrophys. J. 580, 887–895, 2002.). This new result suggests that the inverse power index of the energy spectrum of source electrons responsible for generating diffuse TeV gamma rays through inverse Compton effect should be steeper than 2.2 and 2.1 for IG and OG planes, respectively, with 99%C.L.     

Measurements of trapped protons and cosmic rays from recent Shuttle flights.

We have flown two new charged particle detectors in five recent Shuttle flights. In this paper we report on the dose rate, equivalent dose rate, and radiation quality factor for trapped protons and cosmic radiation separately. A comparison of the integral linear energy transfer (LET) spectra with recent transport code calculations show significant disagreement. Using the calculated dose rate from the omni-directional AP8MAX model with IGRF reference magnetic field epoch 1970, and observed dose rate as a function of (averaged over all geographic latitude) and longitude, we have determined the westward drift of the South Atlantic anomaly. We have also studied the east-west effect, and observed a 'second' radiation belt. A comparison of the galactic cosmic radiation lineal energy transfer spectra with model calculations shows disagreement comparable to those of the trapped protons.     

Effects of gravity and cosmic rays on cell proliferation kinetics in Paramecium tetraurelia.

Space flights resulted in a stimulating effect on kinetics of proliferation in Paramecium tetraurelia. Additional experiments were performed in order to determine the origin of this phenomena. Paramecia were cultivated in balloon flights or in a slow clinostat, or were exposed to different levels of hypergravity. The results suggest that changes in cell proliferation rate are related to cosmic rays and to a direct effect of microgravity.     

Early and late damages induced by heavy charged particle irradiation in embryonic tissue of Arabidopsis seeds.

Early and late effects of accelerated heavy ions (HZE) on the embryonic tissue of Arabidopsis thaliana seeds were investigated seeing that initial cells of the plant eumeristems resemble the original cells of animal and human tissues with continuous cell proliferation. The endpoints measured were lethality and tumorization in the M1-generation for early effects and embryonic lethality in the M2-generation for late effects. The biological endpoints are plotted as functions of the physical parameters of the irradiation i.e. ion fluence (p/cm2), dose (Gray), charge Z and linear energy transfer (LET). The results presented contribute to the estimation of the principles of biological HZE effects and thus may help to develop a unified theory which could explain the whole sequence from physical and chemical reactions to biological responses connected with heavy ion radiation. Additionally, the data of this paper may be used for the discussion of the quality factor for heavy ion irradiation needed for space missions and for HZE-application in radio-therapy by use of accelerators (UNILAC, (SIS/ESR), BEVALAC).     

Depth dependency of neutron density produced by cosmic rays in the lunar subsurface

Depth dependency of neutrons produced by cosmic rays (CRs) in the lunar subsurface was estimated using the three-dimensional Monte Carlo particle and heavy ion transport simulation code, PHITS, incorporating the latest high energy nuclear data, JENDL/HE-2007. The PHITS simulations of equilibrium neutron density profiles in the lunar subsurface were compared with the measurement by Apollo 17 Lunar Neutron Probe Experiment (LNPE). Our calculations reproduced the LNPE data except for the 350–400 mg/cm² region under the improved condition using the CR spectra model based on the latest observations, well-tested nuclear interaction models with systematic cross section data, and JENDL/HE-2007.     

Use of primary cell cultures to measure the late effects in the skins of rhesus monkeys irradiated with protons.

Previous pilot investigations of the uses of primary cell cultures to study late damage in stem cells of the skin of the New Zealand white (NZW) rabbit and the rhesus monkey, have been extended to individual monkeys exposed to 55 MeV protons. Protons of this energy have a larger range in tissue of (approximately 2.6 cm) than the 32 MeV protons (approximately 0.9 cm) to which the animals in our earlier studies had been exposed. Although the primary emphases in the current studies were improvement and simplification in the techniques and logistics of transportation of biopsies to a central analytical facility, comparison of the quantitative measurements obtained thus far for survival of stem cells in the skins from animals irradiated 21 years ago reveals that the effects of both proton energies are similar.     

Detection of meteors and sub-relativistic dust grains by the fluorescence detectors of ultra high energy cosmic rays

Fluorescence detectors of ultra high energy cosmic rays (UHECR) allow to record not only the extensive air showers, initiated by the UHECR particles, but also to detect light, produced by meteors and by the fast dust grains. It is shown that the fluorescence detector operated at the mountain site can register signals from meteors with kinetic energy threshold of about 25 J (meteor mass ∼ 5 × 10⁻⁶ g, velocity ∼ 3 × 10⁶ cm/s). The same detector might be used for recording of the dust grains of smaller mass (of about 10⁻¹⁰ g) but with velocity 10⁹ cm/s, close to the light velocity (sub-relativistic dust grains). The light signal from a sub-relativistic dust grain is expected in much shorter time scale (∼0.001 s), in comparison with the meteor signal (∼0.1–1 s), and much longer than duration of the UHECR signals (tens of μs). The fluorescence detector capable to register various phenomena: from meteors to UHECR – should have a variable pixel and selecting system integration time. A study of the new phenomenon of sub-relativistic grains will help to understand the mechanism of particle and dust grain acceleration in astrophysical objects (in SN explosions, for example).     

The investigation of powerful solar flares characteristics by analysis of excited states of C and various neutrons capture lines

Accelerated energetic particles in solar flares produced nuclear γ-lines in interactions with ambient solar atmosphere. Analysis of intensity of ratios between various γ-lines allows us to make estimations of abundance of elements, parameters of surrounding media and other solar characteristics. In this article we discuss the flux ratio between two lines from excited states of ¹²C (f_15.11/f_4.44) and our results of preliminary calculation of intensity ratio between two neutron capture lines at ³He and ¹H (f_20.58/f_2.223). In particular we consider the opportunity to obtain n(³He)/n(¹H) ratio during solar flares and using high-energy gamma-emission studying, based on the satellite data. Possible interpretation of spectral features observed during the January 20, 2005 solar flare is discussed. Preliminary analysis of energy spectrum in the band of 2–21 MeV gives n(³He)/n(¹H) ∼ 8 × 10⁻⁴ for January 20, 2005 solar flare.     

Be-7 nuclei produced by galactic cosmic rays and solar energetic particles in the earth''s atmosphere

Be-7 radioactive nuclei with a half-life of 53.3 days result from spallation reactions of galactic cosmic rays(GCR) and solar energetic particles (SEP) with N and O nuclei in the Earth's atmosphere. We calculate the average global production of Be-7 in the atmosphere by GCR and SEP The result indicates that an intense SEP event produces a large amount of Be-7 in the polar stratosphere and part of them could be transported to the surface at lower latitudes. The ground-level measurement of Be-7 in Japan exhibits the possibility of enhancement in the Be-7 radioactivity associated with the intense SEP event on July 14, 2000. In addition, the present experiment shows seasonal variations in the surface Be-7 concentration which peaks in spring and autumn. We discuss the possible air mass mixing between the stratosphere and troposphere to explain the measured seasonal variations. The surface concentration of Pb-210 nuclei indicates a similar trend to that of Be-7 and we suggest two possible explanations.     

Study of cosmic rays and light flashes on board Space Station MIR: the SilEye experiment.

The SilEye experiment aims to study the cause and processes related to the anomalous Light Flashes (LF) perceived by astronauts in orbit and their relation with Cosmic Rays. These observations will be also useful in the study of the long duration manned space flight environment. Two PC-driven silicon detector telescopes have been built and placed aboard Space Station MIR. SilEye-1 was launched in 1995 and provided particles track and LF information; the data gathered indicate a linear dependence of FLF(Hz) ( 4 2) 10(3) 5.3 1.7 10(4) Fpart(Hz) if South Atlantic Anomaly fluxes are not included. Even though higher statistic is required, this is an indication that heavy ion interactions with the eye are the main LF cause. To improve quality and quantity of measurements, a second apparatus, SilEye-2, was placed on MIR in 1997, and started work from August 1998. This instrument provides energetic information, which allows nuclear identification in selected energy ranges; we present preliminary measurements of the radiation field inside MIR performed with SilEye-2 detector in June 1998.