ISS crew evolution

A Russian cosmonaut reviews the composition of U.S. and Russian crews and joint activities on International Space Station Expeditions One through Five.     

Life science experiments during the German-Russian MIR '97 mission

Manned spaceflight has been an important element of the German space program over the last decades. This is demonstrated by the nationally managed space missions Spacelab D-l (1985), D-2 (1993), and MIR '92 as well as by the participation in the 1st Spacelab mission FSLP (1983), the NASA missions IML-1 (1992) and IML-2 (1994), as well as in the ESA missions EUROMIR '94 and '95. On February 12th, this year, the German cosmonaut Reinhold Ewald was launched together with his Russian colleagues Wasilij Zibliew and Alexander Lasudkin onboard of a Soyuz spacecraft for another stay of a German cosmonaut onboard of the Russian Space Station MIR. This mission--the so-called German/Russian MIR '97--was, of course, another cornerstone with regard to the cooperation between Russian and German space organizations. The cooperation in the area of manned missions began 1978 with the flight of the German cosmonaut Sigmund Jahn onboard of Salyut 6, at that time a cooperation between the Soviet Union and the German Democratic Republic in the frame of the Interkosmos Program. In March 1992, it was followed by the flight of Klaus Dietrich Flade with his stay onboard of MIR. After two further successful ESA missions, EUROMIR '94 and '95 with the two German cosmonauts Ulf Merbold and Thomas Reiter and with a marked contribution of German scientists, the decision was taken to perform another German/Russian MIR mission, the so-called MIR '97. In Germany, MIR'97 was managed and performed in a joint effort between several partners. DARA, the German Space Agency, was responsible for the overall program and project management, while DLR, the German Aerospace Research Establishment, was responsible for the cosmonaut training, for medical operations, for the mission control at GSOC in Oberpfaffenhofen as well as for user support.     

Deuterium-free water (1H2O) in complex life-support systems of long-term space missions

Heavy water containing deuterium displays toxic property. It is stated that any quantity of a heavy isotope of hydrogen--deuterium--is undesirable to animals and plants. It was earlier shown by us that physical-chemical life support systems on board the "MIR" station fractionate (change) isotopes of hydrogen, oxygen and carbon. Therefore, the problem of regenerative systems in habitable space objects should include removal, from water, of a heavy stable isotope of hydrogen--deuterium. In this article we consider one method of obtaining deuterium-free water--decomposition of distillate water in an electrolyser to hydrogen and oxygen with subsequent synthesis in a catalytic or high-temperature reactor. The influence of deuterium-free water on the growth and development of Arabidopsis thaliana and Japanese quail is investigated. It is shown that with the help of the electrolysis method it is possible to fabricate water containing 80% less deuterium in comparison with SMOW. Experimentally, it is proved on a culture of Arabidopsis thaliana and Japanese quail that water with reduced contents of deuterium (80%) displays positive biological activity.     

Natural killer cells after ALTAIR mission

Reduced in vitro NK cytotoxic activity have routinely been observed after both prolonged and short-term space flights. This study investigated the effects of space flight on NK cell functions, NK cell counts and the production of IL-2 and TNF by lymphocytes of French-Russian crew members. In the French cosmonaut, after 21 days space flight, the cytotoxic activity of NK cells, the capacity the NK cells to bind and lyse the individual target cells and the percentage of NK cells were decreased. In this cosmonaut a twofold reduction TNF production in cultures of lymphocytes stimulated with PMA and with the mixture of PHA and PMA was observed on the first day after landing. However, the activity of the production of TNF in 48-hour PHA-cultures of lymphocytes was unchanged and the biological activity of IL-2 was not reduced. The immunological examination did not detecte any substantial deviations from the norm in both russian cosmonauts after 197 days space flight. Various explanations for decreased cytotoxicity in cosmonauts after space flight can be proposed, and these include the defective function of NK cells and reduced numbers of circulating effector cells.     

智能气囊缓冲器在航天器回收着陆中的应用探讨

文章提出将智能气囊技术应用于飞船返回舱座椅作为返回落地缓冲,设计了智能气囊缓冲器方案,并论述了智能气囊缓冲器在飞船座椅上应用的可行性。与胀环式机械缓冲器比较,智能气囊保持了较高的缓冲效率,同时可使航天员受到的冲击过载特性曲线更加平坦,从而提高航天员着陆的安全性和舒适性。     

载人航天器在轨维修地面仿真验证技术

为满足载人航天器型号对微重力和真空环境下的维修性仿真验证需求,文章提出并实现了一种混合式仿真验证平台。阐述了在轨维修仿真验证平台整体构架,建立了航天员模型、航天服模型及舱体维修模型,给出了在轨微重力和真空环境下进行维修的可视性、可达性及维修操作时间的仿真验证方法。利用该平台对在轨维修任务进行仿真验证,结果表明,该平台可以有效仿真和验证在轨维修,为维修性设计和优化提供了手段。     

Methodological approach to study of cosmonauts errors and its instrumental support

The methodological approach to the study of cosmonauts errors is discussed in the paper. Within its framework an error is considered in psychophysiological aspect as consequence of cosmonaut "psychophysiological troubles" caused by combined effect of flight extreme conditions on his/her organism. This approach was used for the investigation of interrelation between cosmonauts errors, their psychophysiological state and work-rest schedule peculiarities. It includes procedures of expert analysis of data received in the course of radio and TV sessions with crew, analysis of timelines as well deviations in "crew-spacecraft" system functioning. These data are accumulated, systematized and processed in data base. Realization of the suggested approach does not require specialized onboard equipment and crew members time expenditure. Some results of inflight data analysis are presented to illustrate its potentials.     

Long-term variations of fluxes of solar protons and helium isotopes

The fluxes of hydrogen and helium isotopes in the solar wind are reconstructed over a long time scale since the present time up to 600 million years back. Abundances of helium isotopes, obtained in the helium isotopic analysis made for 8 lunar soil samples, were used as initial data in the reconstruction procedure. Samples were taken off from various levels of the 1.6-m core of lunar soil delivered by the automatic Luna-24 station in 1976. The data on modern hydrogen and helium fluxes were used as well. The developed reconstruction procedure allowed one to select various solar wind components in a ??gross?? composition. Proton flux variations over the interval of 600 million years do not exceed a value of 40 %. Helium flux variations reach a value of 1.5?C2 relative to the average value. Most likely, this circumstance is caused by considerable variations of a number of coronal mass ejections (CME) enriched by helium. The arguments in favor of solar activity polycyclicity on a long time scale are discussed.     

Remote assistance experiment during the manned space flight Altair

This remote assistance trial, performed within the framework of the manned space flight Altaïr, was carried out by CADMOS (CNES), with the cooperation of the Sub-directorate of CNES Operational Systems, Medes, LBM of Tours and Christol Consultants. It consisted of supplying the cosmonaut performing the Orthostatism experiment (echograph acquisition) on board the Mir station with realtime assistance by an expert (LBM of Tours) working from the ground on the CADMOS premises. The various steps of the approach followed during the preparation phase are described, as well as the technical means of communication used between the Mir station and CADMOS.     

Geochronology and monitoring of cosmic rays for accumulating cosmogenic isotopes <Superscript>53</Superscript>Mn and <Superscript>10</Superscript>Be in terrestrial rocks

The paper is devoted to discussing the method of measuring the accumulation of radioactive isotopes ⁵³Mn (with a half-life T = 3.7 million years) and ¹⁰Be (T = 2.5 million years) in iron-bearing rocks. Knowledge of the dynamics of the accumulation of these isotopes would allow us to estimate the variations in the intensity of cosmic rays, periods of glaciations and geological changes, as well as climatic processes on the Earth in retrospect of 0.1–10 million years. For an operative study of a large number of samples, it has been proposed to use a low-cost neutron activation method with the implementation of the ⁵³Mn(n, γ)⁵⁴Mn reaction in a slow neutron reactor. As has been shown, using the 10Be isotope together with ⁵³Mn makes it possible to simultaneously determine both the cosmic-ray fluxes and the shielding time of the corresponding region from cosmic radiation. To obtain the reliable data on cosmic rays, it has been proposed to study rock samples from the lunar surface.     

Vestibular tests in the selection of cosmonauts.

Vestibulo-vegetative disorders in cosmonauts and astronauts occurring during space flight compel otolaryngologists to search for vestibular tests enabling a precise evaluation of the activity of the vestibular apparatus and showing disposition to motion sickness. Otoneurological investigation of Polish candidates for cosmonaut status consisted of the following vestibular tests: caloric, rotatory, optokinetic, swinging torsion, statokinesimetric and vestibulo-vegetative. The value of various vestibular tests for aviation and space medicine is presented in this paper, taking into account the results of investigations of the equilibrium system with the group of pilots selected for space flight as well as extensive experience with candidates for the air service and also trained pilots and patients. The relatively frequent lack of correlation between the results of the applied tests, which renders difficult the proper evaluation of the equilibrium system, is emphasized in the paper. Finally, the results of investigations of acute habituation of the vestibular apparatus are discussed.     

Autonomic function testing aboard the ISS using “PNEUMOCARD”

Investigations of blood pressure, heart rate (HR), and heart rate variability (HRV) during long term space flights on board the “ISS” have shown characteristic changes of autonomic cardiovascular control. Therefore, alterations of the autonomic nervous system occurring during spaceflight may be responsible for in- and post-flight disturbances. The device “Pneumocard” was developed to further investigate autonomic cardiovascular and respiratory function aboard the ISS. The hard-software diagnostic complex “Pneumocard” was used during in-flight experiment aboard ISS for autonomic function testing. ECG, photoplethysmography, respiration, transthoracic bioimpedance and seismocardiography were assessed in one male cosmonaut (flight lengths six month). Recordings were made prior to the flight, late during flight, and post-flight during spontaneous respiration and controlled respiration at different rates.HR remained stable during flight. The values were comparable to supine measurements on earth. Respiratory frequency and blood pressure decreased during flight. Post flight HR and BP values increased compared to in-flight data exceeding pre-flight values. Cardiac time intervals did not change dramatically during flight. Pulse wave transit time decreased during flight. The maximum of the first time derivative of the impedance cardiogram, which is highly correlated with stroke volume was not reduced in-flight.Our results demonstrate that autonomic function testing aboard the ISS using “Pneumocard” is feasible and generates data of good quality. Despite the decrease in BP, pulse wave transit time was found reduced in space as shown earlier. However, cardiac output did not decrease profoundly in the investigated cosmonaut.Autonomic testing during space flight detects individual changes in cardiovascular control and may add important information to standard medical control. The recent plans to support a flight to Mars, makes these kinds of observations all the more relevant and compelling.     

Analysis of the pre-flight and post-flight calibration procedures performed on the Liulin space radiation dosimeter

Liulin, a dosimetry-radiometry system, was developed to satisfy the requirements for active flux and dose rate measurements for the flight of the second Bulgarian cosmonaut in 1988. The system consists of a compact battery-operated silicon solid state detector unit and a read/write microcomputer and telemetry unit. We describe the pre-flight calibrations with charged particles, using radioactive sources and accelerated 170 MeV/nucleon proton and alpha particles at the Dubna, Russia cyclotron. We discuss comparisons with data obtained on Mir with the French-built tissue equivalent LET spectrometer NAUSICAA. Lastly, we describe post-flight calibrations performed with 1 GeV/nucleon 56Fe ions at the Brookhaven National Laboratory AGS accelerator, where the instrument was mounted in tandem with several thin position-sensitive silicon detectors behind a stopping target. The silicon detectors provided an energy spectrum for the surviving charged nuclear fragments for which the flux and absorbed dose were recorded by Liulin.     

Results of space experiment program "Interferon"

The results of the biological space experiment "Interferon" performed by two international cosmonaut teams (26 May 1980, and 16 May 1981) aboard space laboratory Solyut-6 are reported: (1) Human lymphocytes separated from blood of healthy donors and placed into "Interferon I" equipment could be kept for 7 days in suspension culture under spaceflight conditions. Interferon production could be induced in human lymphocytes by preparations of different origin: virus, synthetic polyribonucleotides, bacterial protein and plant pigment. An increased lymphocyte interferon production in space laboratory compared to ground control was observed. (2) Human interferon preparations and interferon inducers placed in space laboratory at room temperature for 7 days maintained their biological activity. (3) A decrease of induced interferon production and natural killer activity of lymphocytes isolated from peripheral blood of cosmonauts was observed on the 1st day on Earth after 7-days spaceflight.     

A simplified approach to uncertainty quantification for orbits in impulsive deflection scenarios

For the majority of near-Earth Asteroid (NEA) impact scenarios, optimal deflection strategies use a massive impactor or a nuclear explosive, either of which produce an impulsive change to the orbit of the object. However, uncertainties regarding the object composition and the efficiency of the deflection event lead to a non-negligible uncertainty in the deflection delta-velocity. Propagating this uncertainty through the resulting orbit will create a positional uncertainty envelope at the original impact epoch. We calculate a simplified analytic evolution for impulsively deflected NEAs and perform a full propagation of uncertainties that is nonlinear in the deflection delta-velocity vector. This provides an understanding of both the optimal deflection velocities needed for a given scenario, as well as the resulting positional uncertainty and corresponding residual impact probability. Confidence of a successful deflection attempt as a function of launch opportunities is also discussed for a specific case.     

PHYSIOLAB: a cardiovascular laboratory

PHYSIOLAB is a cardio-vascular laboratory designed by CNES in cooperation with IMBP, with double scientific and medical goals: -a better understanding of the basic mechanisms involved in blood pressure and heart rate regulation, in order to predict and control the phenomenon of cardio-vascular deconditionning. -a real-time monitoring of cosmonauts during functional tests. Launched to the MIR station in 1996, this laboratory was set up and used for the first time by Claudie Andre-Deshays during the French mission "Cassiopeia". The scientific program is performed pre, post and in-flight to study phenomena related to the transition to microgravity as well as the return to the earth conditions. Particular emphasis was placed on the development of the real-time telemetry to monitor LBNP test. This function was successful during the Cassiopeia mission, providing the medical team at TSOUP (MIR Control Center in Moscow) with efficient means to control the physiological state of the cosmonaut. Based on the results of this first mission, IMBP and CNES will go on using Physiolab with Russian crews. CNES will take advantage of the upcoming French missions on MIR to improve the system, and intends to develop a new laboratory for the International Space Station.     

PHYSIOLAB: a new laboratory for the study of the cardio-vascular system

On the basis of the experience gained during the previous french-russian missions on board MIR about the adaptation processes of the cardio-vascular system, a new laboratory has been designed. The objective of this “PHYSIOLAB” is to have a better understanding of the mechanisms underlying the changes in the cardio-vascular system, with a special emphasis on the phenomenon of cardio-vascular deconditioning after landing.

Beyond these scientific objectives, it is also intended to use PHYSIOLAB to help in the medical monitoring on-board MIR, during functional tests such as LBNP.

PHYSIOLAB will be set up in MIR by the French cosmonaut during the next french-russian CASSIOPEE mission in 1996. Its architecture is based on a central unit, which controls the experimental protocols, records the results and provides an interface for transmission to the ground via telemetry. Different specific modules are used for the acquisition of various physiological parameters.

This PHYSIOLAB under development for the CASSIOPEE mission should evolve towards a more ambitious laboratory, whose definition would take into account the results obtained with the first version of PHYSIOLAB. This “second generation” laboratory should be developed in the frame of wide international cooperation.     

The Use of Quaternions in the Optimal Control Problems of Motion of the Center of Mass of a Spacecraft in a Newtonian Gravitational Field: I

The problem of optimal control is considered for the motion of the center of mass of a spacecraft in a central Newtonian gravitational field. For solving the problem, two variants of the equations of motion for the spacecraft center of mass are used, written in rotating coordinate systems. Both the variants have a quaternion variable among the phase variables. In the first variant this variable characterizes the orientation of an instantaneous orbit of the spacecraft and (simultaneously) the spacecraft location in this orbit, while in the second variant only the instantaneous orbit orientation is specified by it. The suggested equations are convenient in the respect that they allow the general three-dimensional problem of optimal control by the motion of the spacecraft center of mass to be considered as a composition of two interrelated problems. In the first variant these problems are (1) the problem of control of the shape and size of the spacecraft orbit and (2) the problem of control of the orientation of a spacecraft orbit and the spacecraft location in this orbit. The second variant treats (1) the problem of control of the shape and size of the spacecraft orbit and the orbit location of the spacecraft and (2) the problem of control of the orientation of the spacecraft orbit. The use of quaternion variables makes this consideration most efficient. The problem of optimal control is solved on the basis of the maximum principle. Several first integrals of the systems of equations of the boundary value problems of the maximum principle are found. Transformations are suggested that reduce the dimensions of the systems of differential equations of boundary value problems (without complicating them). Geometrical interpretations are given to the transformations and first integrals. The relation of the vectorial first integral of one of the derived systems of equations (which is an analog of the well-known vectorial first integral of the studied problem of optimal control) with the found quaternion first integral is considered. In this paper, which is the first part of the work, we consider the models of motion of the spacecraft center of mass that employ quaternion variables. The problem of optimal control by the motion of the spacecraft center of mass is investigated on the basis of the first variant of equations of motion. An example of a numerical solution of the problem is given.     

In situ dating on Mars: A new approach to the K–Ar method utilizing cosmogenic argon

Cosmogenic argon isotopes are produced in feldspars via nuclear reactions between cosmic rays and Ca and K atoms within the lattice. These cosmogenic isotopes can be used as proxies for K and Ca, much like nuclear reactor-derived ³⁹Ar and ³⁷Ar are used as proxies for K and Ca, respectively, in ⁴⁰Ar/³⁹Ar geochronology. If Ca and K are uniformly distributed, then the ratio of radiogenic ⁴⁰Ar (⁴⁰Ar^?) to cosmogenic ³⁸Ar or ³⁶Ar (³⁸Ar_cos or ³⁶Ar_cos) is proportional to the difference between the radioisotopic and exposure ages, as well as the K/Ca ratio of the degassing phase. Thus cosmogenic, radiogenic, and trapped Ar isotopes, all of which can be measured remotely and are stable over geologic time, are sufficient to generate an isochron-like diagram from which the isotopic composition of the trapped component may be inferred. Such data also provide a means to assess the extent to which the system has remained closed with respect to ⁴⁰Ar^?, thereby mitigating otherwise unquantifiable uncertainties that complicate the conventional K–Ar dating method.     

最优双冲量交会问题的数学建模与数值求解

基于普适变量法研究了两个共面轨道的最优双冲量交会问题。具体地,基于求解Lambert问题的普适变量法,在将给定时间段划分初始飘移阶段、轨 道转移阶段与终端停泊阶段的前提下,对两圆轨道及两拱线相同的椭圆轨道的最优双冲量交 会问题分别进行了优化数学建模,并利用数学软件Lingo进行了数值求解。数值结果表明,划分给定时间段可以得到更优解。