Neurohumoral mechanism of space motion sickness.

This paper reviews existing hypotheses concerning the mechanisms of adaptation of the vestibular apparatus and related somatosensory systems to microgravity with reference to the flight data. Having in view theoretical concepts and experimental data accumulated in space flights, a conceptual model of the development of a funtional system responsible for the termination of vestibular dysfuntion and space motion sickness manifestations is presented. It is also shown that changes in the hormonal status during motion sickness induced by vestibular stimulation give evidence that endocrine regulation of certain functions can be involved in adaptive responses.     

Male and female characteristics in vestibular testing: a step toward the selection of the best participants for space flight

Vestibular disturbances in connection with space flight were reported by a majority of participating astronauts and cosmonauts. These include motion sickness symptoms in the first few days of the space flight, as well as standing, gait and orientation disturbances after the return to Earth. The Aerospace Medical Community has been trying to select those people that are particularly adapted to the above stresses or that can be further adapted through training programs. As the circle of selectees extends to women, the problem arises as to whether differences between men and women exist under the conditions of space flight. In seeking answers to this question we studied a group of 42 women and 44 men, who were further subdivided according to their subjective motion sickness sensitivity, as determined by a questionnaire. Using this material, 26 men and 22 women were designated as motion sickness resistant, and 18 men and 20 women were designated as nonresistant. The vestibular test battery given these test subjects consisted of caloric, rotatory, optokinetic, vestibulo-spinal and vestibulo-vegetative testing. Because of the mixed orthostatic and vestibular problems seen after space flights, we also studied the response of the vestibular apparatus during peripheral blood pooling as induced by lower body negative pressure. The collected historical and test data are analyzed in this paper with emphasis on the relationship to motion sickness tendency.     

The visual stress model--a psycho-physiological method for the evaluation of operational reliability of pilots and cosmonauts.

An experimental psycho-physiological method is presented for the evaluation of visual-cognitive performance preconditions and operational reliability of pilots and cosmonauts. As visual-cognitive stress are used tachistoscopically presented instrument symbols under conditions of individual speed of work and time pressure. The results of the compared extreme groups consisting of pilots with good and insufficient flight performance showed that the pilots with impairments to the quality of flight activity differ already before the test in their individual habitual characteristics and actual motivation, during the stress in their operational parameters, in the dimensions of their cardiorespiratory activation as well as in their efficiency and after the stress in their subjective experience of the stress. Conclusions are drawn for the evaluation of the aptitude of pilots and cosmonauts.     

Vestibular factors influencing the biomedical support of humans in space

This paper will describe the biomedical support aspects of humans in space with respect to the vestibular system. The vestibular system is thought to be the primary sensory system involved in the short-term effects of space motion sickness although there is increasing evidence that many factors play a role in this complex set of symptoms. There is the possibility that an individual's inner sense of orientation may be strongly coupled with the susceptibility to space motion sickness. A variety of suggested countermeasures for space motion sickness will be described. Although there are no known ground-based tests that can predict space motion sickness, the search should go on. The long term effects of the vestibular system in weightlessness are still relatively unknown. Some preliminary data has shown that the otoconia are irregular in size and distribution following extended periods of weightlessness. The ramifications of this data are not yet known and because the data was obtained on lower order animals, definitive studies and results must wait until the space station era when higher primates can be studied for long durations. This leads us to artificial gravity, the last topic of this paper. The vestibular system is intimately tied to this question since it has been shown on Earth that exposure to a slow rotating room causes motion sickness for some period of time before adaptation occurs. If the artificial gravity is intermittent, will this mean that people will get sick every time they experience it? The data from many astronauts returning to Earth indicates that a variety of sensory illusions are present, especially immediately upon return to a 1-g environment. Oscillopsia or apparent motion of the visual surround upon head motion along with inappropriate eye motions for a given head motion, all indicate that there is much to be studied yet about the vestibular and CNS systems reaction to a sudden application of a steady state acceleration field like 1-g. From the above information it is obvious that the vestibular system does have unique requirements when it comes to the biomedical support of space flight. This is not to say that other areas such as cardiovascular, musculo-skeletal, immunological and hematological systems do not have their own unique requirements but that possible solutions to one system can provide continuing problems to another system. For example, artificial gravity might be helpful for long term stabilization of bone demineralization or cardiovascular deconditioning but might introduce a new set of problems in orientation, vestibular conflict and just plain body motion in a rotating space vehicle.     

Otorhinolaryngological problems in medical support of space flights

At present the main trends among the most important problems of otorhinolaryngology in space medicine have become defined as vestibulology, audiology and clinical aspects (prophylaxis, diagnosis and treatment of ENT diseases in flight). The principal result of recent vestibular studies has probably been the establishment of an apparent relationship between the resistance of the vestibular system to adequate ground-based stimulation and tolerance to space flight. The findings of the studies formed the basis for the development of a new system of vestibular selection, as well as demonstrated the usefulness of special vestibular training of astronauts by active and passive methods. In audiology certain urgency is acquired by the problem of noise limitation in space cabins and auditory system reliability prediction for preserving a high work capability in crew members. The hemodynamic changes in weightlessness, as well as the possibility for allergic lesions, create conditions for distorted course of the ENT diseases and vaso-motor disorders. The prophylaxis of aspirations also deserves close attention since the possibilities of their onset increase in weightlessness. The rendering of immediate, timely aid will depend not only on the presence of the necessary medical equipment but also on the ability of the crew members to render the appropriate otorhinolaryngological aid.     

基于气浮台的编队飞行地面试验建模与鲁棒控制器设计

为分析验证卫星编队飞行涉及的相对导航、制导与控制以及星间通信等问题,搭建了编队飞行的地面试验系统,采用了一块3m×4.5m的气浮平台和具有两个平动自由度和一个转动自由度的卫星仿真器分别来模拟低阻力的空间环境和编队飞行的卫星,相对导航采用了视觉相机和室内GPS两种方案,星间通信则通过蓝牙进行模拟。推导了描述仿真器间相对运动的包含参数不确定性的动力学模型,并基于此模型设计了带极点配置的鲁棒H∞控制算法,通过姿态同步和构型保持等仿真实验重点对编队飞行的相对导航、星间通信和相对状态控制进行分析验证,对实际的编队任务具有一定的参考和指导意义。     

Changes in the vestibular function during space flight

An analysis of observations and investigations carried out in space flight has shown that some cosmonauts and astronauts have experienced vestibular disorders during the transition to weightlessness. Vestibular-sensory disorders include: Spatial illusions (the feelings of falling down, being in an upside-down position, the sensations of rotation of the craft or the body) and vertigo occurring during the onset of the orbital flight and head movements; Feelings, similar to those experienced in response to Coriolis accelerations on the Earth, which occasionally develop in weightlessness during the spacecraft rotation upon abrupt head and body movements and restrained feet; Feelings "of the load on the vestibular analyser which is unlike any Earth-bound effects" upon abrupt head movements during the first hours of an orbital flight and "a prolonged movement" during the switch-off of thrusters in weightlessness. Vestibular-vegetative disorders comprise a complex of symptoms similar to those of motion sickness: loss of appetite, stomach awareness (12%), hypersalination, nausea (9.6%) and vomiting (4.8%). Soviet studies suggest that the vestibular tolerance to the flight effects depends on the natural stability and training to the cumulative effect of adequate vestibular stimuli. This has been used in the development of the system of vestibular selection. Changes in the vestibular function seem to play the major role in the development of motion sickness in weightlessness, extra-labyrinthine factors being contributory. The current hypotheses have not yet been adequately confirmed in experiments. A detailed physiological analysis allows the conclusion that the decisive factor in the development of motion sickness may be the disturbance of the function of analysers responsible for spatial orientation which take the form of sensory conflicts as well as an altered reactivity of the organism due to the hemodynamic rearrangement.     

GPS转发测量系统在空间目标拦截试验应用前景及相关问题探讨

介绍美国利用 GPS进行空间目标相对几何测量方面的研究情况。地面动态试验结果表明 ,利用 GPS能达到 2 cm的相对定位精度 ,可满足目标拦截试验需要。对涉及的 GPS转发器、双频 P码、信号传输和定位精度等技术问题作了分析 ,提出一些新的设想。     

Nausogenic properties of various dynamic and static force environments.

Motion sickness can occur when an accelerating force acting on the human body repeatedly changes amplitude and direction or both. It also can occur without any motion after transfer into a constant force field significantly different from Earth-gravity. Dynamic and static causes of motion sickness can be distinguished accordingly. Space sickness, too, has dynamic as well as static aspects. Dynamic space sickness might depend on increased bilateral differential sensitivity of the peripheral and central vestibular apparatus, whereas static space sickness may be caused by erroneous compensation of bilaterial asymmetries of the otolith-system in the microgravity environment. Experiments in airplanes, cars and on a vestibular sled have shown that the susceptibility to motion sickness is highest for changes of acceleration in the negative X-axis (as compared to the other axes) of the body. During reciprocating linear accelerations on the vestibular sled, standstill periods of movement and the direction of movement cannot correctly be indicated, because the peripheral vestibular apparatus lacks true motion detectors.     

利用地月间空间站的载人登月飞行模式分析

为提高空间站利用率,降低载人登月任务成本,有效开发地月空间,研究了基于地月空间不同轨道空间站的载人登月飞行模式。首先对比直接往返登月飞行模式,对基于空间站的载人登月飞行模式进行任务分析,通过空间站将载人登月任务解耦为载人天地往返任务和登月任务两部分;其次通过轨道设计和稳定性分析提出考虑登月任务需求的地月间空间站可运行轨道和停泊点;最后建立一套飞行模式评价模型,从速度增量需求、飞行时间、空间环境、登月任务窗口、测控条件、交会对接技术难度、后续任务支持性和任务可靠性方面对6种不同位置空间站的登月飞行模式进行分析和定量评价。评价结果表明基于L2点Halo轨道空间站的载人登月飞行模式为更优飞行模式。     

我国空间环境试验的现状与发展建议

文章简要回顾了我国空间环境试验的发展历史与现状,并根据我国空间技术发展的需求,从大型复杂航天器环境试验、长寿命航天器环境适应性评估验证与防护、空间环境及其效应在轨飞行实验、月球与深空环境模拟与试验等方面对我国空间环境试验技术发展提出了一些建议。     

Conceptual study and key technology development for Mars Aeroflyby sample collection

Conceptual study of Mars Aeroflyby Sample Collection (MASC) is conducted as a part of the next Mars exploration mission currently entertained in Japan Aerospace Exploration Agency. In the mission scenario, an atmospheric entry vehicle is flown into the Martian atmosphere, collects the Martian dust particles as well as atmospheric gases during the guided hypersonic flight, exits the Martian atmosphere, and is inserted into a parking orbit from which a return system departs for the earth to deliver the dust and gas samples. In order to accomplish a controlled flight and a successful orbit insertion, aeroassist orbit transfer technologies are introduced into the guidance and control system. System analysis is conducted to assess the feasibility and to make a conceptual design, finding that the MASC system is feasible at the minimum system mass of 600 kg approximately. The aerogel, which is one of the candidates for the dust sample collector, is assessed by arcjet heating tests to examine its behavior when exposed to high-temperature gases, as well as by particle impingement tests to evaluate its dust capturing capability.     

Test results of the air turbo ramjet for a future space plane

The Institute of Space and Astronautical Science (ISAS) has been engaged in the development study on the Air Turbo Ramjet (ATR) engine since 1986 in cooperation with the Ishikawajima Harima Heavy Industries Co. Ltd (IHI). The ATR is one of the most preferable candidates for the propulsion system of a future space plane. Our ATR engine is a combined cycle air breathing propulsion system which consists of the turbojet and the fan boosted ramjet using the liquid hydrogen as a fuel. This engine system was named “ATREX” after employing the expander cycle. The ATREX is energized by thermal energy extracted regeneratively in both the pre-cooler installed in the air intake and the heat exchanger in combustion chamber. The ATREX works in the flight condition from sea level static up to Mach 6 at 35 km altitude. The ATREX employs the tip turbine configuration for compactness of turbo machinery. We are assessing the feasibility of the ATREX system by the sea level static tests using the 1/4-scale model (ATREX-500) with a fan inlet diameter of 300 mm and overall length of 2120 mm. In 1990, the ATREX-500 engine was tested in a sea level static condition to verify the performance characteristics of the turbo machinery and the combustor. In September of 1991, the heat exchanger was installed in the combustion chamber and tested independently from the turbo system. In November of 1991, the heat exchanger was coupled with the turbo system and tested to verify the overall system of the ATREX. In this paper are presented the test results of the ATREX-500 engine tested in the sea level static condition.     

A Ticket pricing strategy for an oligopolistic space tourism market

It is important for any new launch system to develop a successful pricing strategy and to optimize launch system parameters to receive a high economic profit. A question arises, what will happen when an existing suborbital flight market (the first likely to be established in space) is interfered with by a new established orbital flight market for space tourism. There is a risk that the suborbital space tourism market could be almost instantly displaced when a product capable of reaching orbit was introduced. This is best discussed using the following three cases whose results are presented in this paper. Case A presents a ticket pricing strategy for a suborbital and orbital vehicle if the two vehicles do not compete in the same market. Case B shows the necessary ticket pricing strategy for a suborbital vehicle if there is competition from an orbital flight operator. However, the suborbital vehicle would not be able to keep up with a drop in ticket prices due to its obsolete characteristics. Thus, the suborbital vehicle would be forced to stop operation in the year when flight costs became higher than flight receipts as shown in case C.     

CROCODILE: an automated apparatus for organic crystal growth from solution

CROCODILE (CROissance de Cristaux Organiques par DIffusion Liquide dans l'Espace) is a space instrument dedicated to crystal growth from solution. The selected material N (4 nitrophenyl) (L) prolinol (NPP) is the result of studies on organic crystal in the frame of an extended program initiated by CNES for many years. The apparatus was flown aboard PHOTON, an automatic satellite, in April 1990, for a flight duration of more than 15 days. This paper describes the instrument design, with emphasis on specific and original technology well adapted to crystal growth from solution, and extendable to any space experiment on fluids. Preliminary details of the flight campaign will also be discussed.     

Space motion sickness

Space motion sickness, presumably triggered by sudden entry into a weightless environment, occurred with unexpected frequency and severity among astronauts who flew the Skylab missions. Recovery from symptoms was complete within 3-5 days, and as revealed by the Skylab M131 Human Vestibular Function Experiment, all crewmembers were immune to experimentally induced motion sickness after mission day 8. This syndrome has been recognized as a possible threat to the early mission well-being and operational efficiency of at least some individuals who will fly space missions in the future. The causes of space motion sickness are not clearly understood, nor have satisfactory methods been identified to date for its prediction, prevention and treatment. In order to minimize the potential impact of this syndrome on Space Shuttle crew operations the National Aeronautics and Space Administration has organized a broad program of inter-disciplinary research involving a large number of scientists in the United States. Current research on the etiology of space motion sickness is based to a large extent on the so called sensory conflict theory. Investigations of the behavioral and neurophysiological consequences of intralabyrinthine, as well as intermodality sensory conflict are being performed. The work in this area is being influenced by the presumed alterations that occur in otolith behavior in weightlessness. In addition to sensory conflict, the possible relationship between observed cephalad shifts of body fluids in weightlessness and space motion sickness is being investigated. Research to date has failed to support the fluid shift theory. Research underway to identify reliable test methods for the prediction of susceptibility to space motion sickness on an individual basis includes attempts to (a) correlate susceptibility in different provocative environments; (b) correlate susceptibility with vestibular and non-vestibular response parameters, the latter including behavioral, hemodynamic and biochemical factors and (c) correlate susceptibility with rate of acquisition and length of retention of sensory adaptation. Controlled studies are also being performed during parabolic flight as a means of attempting to validate predictive tests for susceptibility to this syndrome. Research to develop new or improved countermeasures for space motion sickness is underway in two primary areas. One of these involves anti-motion sickness drugs. Significant achievements have been realized with regard to the identification of new highly efficacious drug combinations, dose levels and routes of administration. Although pronounced individual variations must be accounted for in selecting the optimum drug and dose level, combinations of promethazine plus ephedrine or scopolamine plus dexidrine are presently the drugs of choice. Work is also underway to identify side effects associated with anti-motion sickness drug use and to identify new drugs which may selectively modify activity in central neural pathways involved in motion sickness. In addition to research on drugs, efforts are being made to develop practical vestibular training methods. Variables which influence rate of acquisition of adaptation, length of retention of adaptation and transfer of protective adaptation to new environments are being evaluated. Also, included in this area is the use of biofeedback and autogenic therapy to train individuals to regulate autonomic responses associated with motion sickness. While valuable new knowledge is expected to evolve from these combined research programs, it is concluded that the final validation of predictive tests and countermeasures will require a series of controlled space flight experiments.     

Plasma and urine catecholamine levels in cosmonauts during long-term stay on Space Station Salyut-7.

The activity of the sympathetic adrenal system in cosmonauts exposed to a stay in space lasting for about half a year has so far been studied only by measuring catecholamine levels in plasma and urine samples taken before space flight and after landing. The device "Plasma 01", specially designed for collecting and processing venous blood from subjects during space flight on board the station Salyut-7 rendered it possible for the first time to collect and freeze samples of blood from cosmonauts in the course of a long-term 237-day space flight. A physician-cosmonaut collected samples of blood and urine from two cosmonauts over the period of days 217-219 of their stay in space. The samples were transported to Earth frozen. As indicators of the sympathetic adrenal system activity, plasma and urine concentrations of epinephrine and norepinephrine as well as urine levels of the catecholamine metabolites metanephrine, normetanephrine, and vanillylmandelic acid were determined before, during and after space flight. On days 217-219 of space flight plasma epinephrine and norepinephrine levels were slightly increased, yet not substantially different from normal. During stress situations plasma norepinephrine and epinephrine levels usually exhibit a manifold increase. On days 217-219 of space flight norepinephrine and epinephrine levels in urine were comparable with pre-flight values and the levels of their metabolites were even significantly decreased. All the parameters studied, particularly plasma norepinephrine as well as urine norepinephrine, normetanephrine, and vanillylmandelic acid, reached the highest values 8 days after landing. The results obtained suggest that, in the period of days 217-219 of the cosmonauts stay in space in the state of weightlessness, the sympathetic adrenal system is either not activated at all or there is but a slight activation induced by specific activities of the cosmonauts, whereas in the process of re-adaptation after space flight on Earth this system is considerably more markedly activated.     

航天器公用空间搭载试验平台设计

我国航天器搭载试验包括空间材料实验、航天医学实验和航天新技术验证试验,具有数据量大、需要实时传输、工作模式多样等特点。文章根据试验项目的需求,设计了应用于低轨道航天器的支持各类空间搭载试验项目的公用试验平台。地面测试验证和在轨运行情况表明,该平台在不影响飞行器平台安全的同时,满足了对试验项目的工作控制、遥测监视及试验数据传输管理的任务要求。     

发展X-37B空间飞机的背后动因分析

文章通过对X-37B飞行器的飞行试验任务分析,指出了X-37B飞行器不是空天飞机,也不是全球快速打击平台,而是一种低成本太空进入能力的飞行验证器,它的作用定位在空间而不是在空中。通过飞行试验和验证试验,旨在打造一个可重复使用的轨道转移运载器。将美国2010年航天战略的重大调整、国际空间站的运行延期和航天飞机退役等事件结合起来,对X-37B发展的背后动因进行分析,有助于了解美国航天发展的未来趋势。经过动因的详尽分析,指出要特别关注美国航天战略调整的两个重心转向,尤其是两个转向背后的动机。如何正确地认识国际空间站的作用定位,对于审视载人航天的未来发展有重要意义。美国航天战略的调整使载人航天的重心回到近地轨道上。基于中国目前的能力现实,建议中国的载人航天重心放在地球轨道上,做好各种能力的建设,并利用这些能力把地球轨道上的事做得更好。     

Thrust chamber health monitoring

With the arrival of the reusable space propulsion systems, the new field of propulsion system health monitoring is emerging. Health monitoring consists of measuring and reviewing engine operating parameters which will warn of engine deterioration or abnormal operation well in advance of any failure. The health monitoring data can be used to establish that an engine should be repaired or replaced, thereby avoiding a future flight failure. This paper presents a status report on the development of a health monitoring system for regeneratively cooled thrust chambers. The system employs a single measurement with a simple nonintrusive sensor to monitor the operation of the engine. The basic measuring and sensor concept is explained and the results of both laboratory and engine firing tests with the health monitoring system are presented.