Evaluation of using two-phase frictional pressure drop correlations for normal gravity to microgravity and reduced gravity

The calculation of two-phase frictional pressure drop (TPFPD) is required by two-phase systems operating under microgravity and reduced gravity. There are a large number of correlations for the TPFPD in tubes under normal gravity. However, it is hard to find out a TPFPD correlation obtained from microgravity and/or reduced gravity conditions, and thus people have to use TPFPD correlations for normal gravity to calculate TPFPD under microgravity and reduced gravity. It is necessary to evaluate the feasibility of such practice. This paper offers a comprehensive review of the TPFPD correlations for normal gravity and an up-to-data survey of the TPFPD experimental study under microgravity and reduced gravity. There are 23 TPFPD correlations for normal gravity reviewed and 135 experimental data under microgravity obtained from the literature. These experimental data are used to evaluate the reviewed TPFPD correlations. It is found that the smallest mean absolute relative deviation (MARD) of the correlations is greater than 34%. Using TPFPD correlations for normal gravity to reduced gravity and microgravity may be acceptable for the first approximation, but correlations intended for microgravity and reduced gravity are needed and more experiments are desired to obtain more data with high accuracy.     

微重力下胶原蛋白纤维化及羟基磷灰石结晶的初步研究

在长期空间飞行过程中, 骨质丢失是一个严重问题. 羟基磷灰石(HAP)晶体是骨骼的主要成分, 骨骼中的胶原蛋白纤维在HAP生长结晶过程中起到关键作用. 研究了胶原蛋白纤维化过程在模拟微重力和常重力条件下的变化, 对以胶原 蛋白纤维作为模板生长出的HAP晶体形貌进行了观察. 结果表明, 不同浓度胶原蛋白溶液中形成的胶原蛋白纤维, 其内部孔隙数量和尺寸在模拟微重力条件下要明显大于常重力条件下, 胶原蛋白纤维内部孔隙的分布也不同于常重力条 件下的结果. 以模拟微重力条件下形成的胶原蛋白纤维为模板生长出的HAP 晶体主要为立方体状, 而以常重力条件下形成的胶原蛋白纤维为模板生长出的 HAP晶体形貌主要为板状. 该结果有助于未来进一步阐明空间骨质丢失的机理.      

Effect of gravity field on the nonequilibrium/nonlinear chemical oscillation reactions.

Biological systems have evolved for a long time under the normal gravity. The Belousov-Zhabotinsky (BZ) reaction is a nonlinear chemical system far from the equilibrium that may be considered as a simplified chemical model of the biological systems so as to study the effect of gravity. The reaction solution is comprised of bromate in sulfuric acid as an oxidizing agent, 1,4-cyclohexanedione as an organic substrate, and ferroin as a metal catalyst. Chemical waves in the BZ reaction-diffusion system are visualized as blue and red patterns of ferriin and ferroin, respectively. After an improvement to the tubular reaction vessels in the experimental setup, the traveling velocity of chemical waves in aqueous solutions was measured in time series under normal gravity, microgravity, hyper-gravity, and normal gravity using the free-fall facility of JAMIC (Japan Microgravity Center), Hokkaido, Japan. Chemical patterns were collected as image data via CCD camera and analyzed by the software of NIH image after digitization. The estimated traveling velocity increased with increasing gravity as expected. It was clear experimentally that the traveling velocity of target patterns in reaction diffusion system was influenced by the effect of convection and correlated closely with the gravity field.     

对连续流式电泳简化数学模型的研究

用有限分析法对连续流式电泳的电流体力学过程进行了三维数值模拟。数值结果表明,Ｐｏｌｅｚｈａｅｖ（［１,２］）等人提出的电泳简化数学模型在处理重力条件下有回流问题时,所得结果与三维准确方程的计算结果严重不符。因此该模型不能用于重力有回流问题。为了克服上述缺陷,在解析分析的基础上,文章提出了一个新的电泳问题简化数学模型。数值计算显示,该模型所得结果与三维准确方程的计算结果十分吻合。     

Possible actions of gravity on the cellular machinery.

Since the first flight of the ESA Biorack on the German Spacelab Mission D1 in 1985 evidence has been obtained that biological cells and small unicellular organisms function differently under conditions of microgravity. However, there is still lack of scientific proof that these effects are caused by a direct influence on the cells in the weightlessness condition. The question how normal gravity may play a role in cellular activity is being addressed and the results show that gravity may provide important signals during certain state transitions in the cell. These would be gravity-sensitive windows in the biological process. Also, by amplification mechanisms inside the cell, the cell may assume a state that is typical for normal gravity conditions and would change in microgravity. Experimental tools are discussed that would provide the conditions to obtain evidence for direct action of gravity and for the possible existence of gravity-sensitive windows.     

Identification of specific gravity sensitive signal transduction pathways in human A431 carcinoma cells.

Epidermal growth factor (EGF) activates a well characterized signal transduction cascade in human A431 epidermoid carcinoma cells. The influence of gravity on EGF-induced EGF-receptor clustering and early gene expression as well as on actin polymerization and actin organization have been investigated. Different signalling pathways induced by the agents TPA, forskolin and A23187 that activate gene expression were tested for sensitivity to gravity. EGF-induced c-fos and c-jun expression were decreased in microgravity. However, constitutive beta-2 microglobulin expression remained unaltered. Under simulated weightlessness conditions EGF- and TPA-induced c-fos expression was decreased, while forskolin- and A23187-induced c-fos expression was independent of the gravity conditions. These results suggest that gravity affects specific signalling pathways. Preliminary results indicate the EGF-induced EGF-receptor clustering remained unaltered irrespective of the gravity conditions. Furthermore, the relative filamentous actin content of steady state A431 cells was enhanced under microgravity conditions and actin filament organization was altered. Under simulated weightlessness actin filament organization in steady state cells as well as in EGF-treated cells was altered as compared to the 1 G reference experiment. Interestingly the microtubule and keratin organization in untreated cells showed no difference with the normal gravity samples. This indicates that gravity may affect specific components of the signal transduction circuitry.     

Modeling and analysis of Earth’s gravity field measurement performance by inner-formation flying system

The Earth’s gravity field can be measured with high precision by constructing the purely gravitational orbit of the inner-satellite in Inner-formation Flying System (IFS), which is independently proposed by Chinese scholars and offers a new way to carry out gravity field measurement by satellite without accelerometers. In IFS, for the purpose of quickly evaluating the highest degree of recovered gravity field model and geoid error as well as analyzing the influence of system parameters on gravity field measurement, an analytical formula was established by spectral analysis method. The formula can reflect the analytical relationship between gravity field measurement performance and system parameters such as orbit altitude, the inner-satellite orbit determination error, the inner-satellite residual disturbances, data sampling interval and total measurement time. This analytical formula was then corrected by four factors introduced from numerical simulation of IFS gravity field measurement. By comparing computation results from corrected analytical formula and the actual gravity field measurement performance by CHAMP, the correctness and rationality of this analytical formula were verified. Based on this analytical formula, the influences of system parameters on IFS gravity field measurement were analyzed. It is known that gravity field measurement performance is a monotone decreasing function of orbit altitude, the inner-satellite orbit determination error, the inner-satellite residual disturbances, data sampling interval and the reciprocal of total measurement time. There is a match relationship between the inner-satellite orbit determination error and residual disturbances, in other words, the change rate of gravity field measurement performance with one of them is seriously restricted by their relative size. The analytical formula can be used to quantitatively evaluate gravity field measurement performance fast and design IFS parameters optimally. It is noted that the analytical formula and corresponding conclusions are applied to any gravity satellite which measures gravity field by satellite perturbation orbit.     

An improved altimeter-derived gravity anomaly from shipborne gravity based on the mean sea surface height constraint factors method

Coastal marine gravity modeling faces challenges due to the degradation of the quality and poor coverage of altimeter data in coastal regions. The effective fusion of shipborne gravity data and altimeter-derived marine gravity data can make shipborne gravity data more useful for the accurate estimation of altimeter-derived coastal marine gravity. A mean sea surface height constraint factor (MSSHCF) method based on the ordinary kriging method and the remove-restore technique is proposed to fuse altimeter-derived gravity model with shipborne gravity data. In this method, all data are standardized during the interpolation process to reduce the error and mean sea surface as a vertical variable is added to the semi-variance function in ordinary kriging to obtain the residual shipborne gravity as corrected data source. The coastal marine gravity models V2.1 and V3.1 which fused altimeter-derived gravity data with shipborne gravity data and V1.1 without shipborne gravity data at a spatial resolution of 1′×1′ can be obtained. Validation experiments show that the accuracy of the gravity model V3.1 obtained by the MSSHCF method more closely agrees with the validated gravity model DTU17 and SS V31 than the model V2.1 obtained by the ordinary kriging interpolation method and the V1.1 model. Our results were validated against shipborne gravity data; the accuracy of model V3.1 was 4.95 % higher than the model V1.1 in South China Sea area A and 2.48 % higher in South China Sea area B. Meanwhile, the accuracy of model V3.1 was 2.07 % higher than model V2.1 in South China Sea area A and 2.42 % higher in South China Sea area B. The effects of distance from the coast and sea depth on the marine gravity model were also evaluated. The results show that the gravity model V3.1 has higher accuracy with the change in ocean distance and depth than the V2.1 and V1.1 gravity models. Thus, our study shows that the MSSHCF method effectively refines coastal altimeter-derived gravity using shipborne gravity data.     

Graviresponses in fungi.

Although the orientation of mycelial hyphal growth is usually independent of the gravity vector, individual specialised hyphae can show response to gravity. This is exemplified by the sporangiophore of Phycomyces, but the most striking gravitropic reactions occur in mushroom fruit bodies. During the course of development of a mushroom different tropisms predominate at different times; the young fruit body primordium is positively phototropic, but negative gravitropism later predominates. The switch between tropisms has been associated with meiosis. The spore-bearing tissue is positively gravitropic and responds independently of the stem. Bracket polypores do not show tropisms but exhibit gravimorphogenetic responses: disturbance leads to renewal of growth producing an entirely new fruiting structure. Indications from both clinostat and space flown experiments are that the basic form of the mushroom (overall tissue arrangement of stem, cap, gills, hymenium, veil) is established independently of the gravity vector although maturation, and especially commitment to the meiosis-sporulation pathway, requires the normal gravity vector. The gravity perception mechanism is difficult to identify. The latest results suggest that disturbance of cytoskeletal microfilaments is involved in perception (with nuclei possibly being used as statoliths), and Ca2(+)-mediated signal transduction may be involved in directing growth differentials.     

变重力场中散体颗粒堆的安息角及接触力分布

为研究重力与散体颗粒堆安息角的关系,针对颗粒系统的随机性和离散性特点,通过三维离散单元法建立颗粒的运动模型,对颗粒在不同重力场中的堆积过程进行了模拟,得出了颗粒堆的安息角及接触力概率分布.结果表明:颗粒堆内接触力构成的力链呈非规则网络状,其中,接触力近似对数正态分布,约65%接触力低于平均值;接触点中约70%处于临界滑移,其余接触点切向力与法向力的比值为均匀分布;不同重力场中颗粒堆接触力的分布规律具有相似性,即接触力相对重力无量纲化之后,其分布函数高度相符;颗粒堆的微观结构具有随机性差异,但是安息角不受重力大小的影响.     

Annealing of Hg2Cl2 crystals — Project of the experiment

The creep of polycrystalline Hg₂X₂ (where X = Cl, Br, J) under the terrestrial and space conditions is studied in the present experiment. The authors suppose that the creep of the Hg₂X₂ cylindrical sample can be studied by the help of the theory of micropolar (non-Newtonian) fluids. In accordance with this theory we obtain the flux of fluid through any cross-section as functions of the radius, viscosity coefficients, the gradient of pressure and the gravity acceleration. In this paper a comparison of the theoretical results for normal and zero- gravity conditions is given. It is shown that the annealing of materials having a broad region of plasticity under microgravity conditions can lead to great improvement in optical as well as mechanical qualities of the crystal. Technical aspects of the experiment are also described.     

Calcium signaling in plant cells in altered gravity.

Changes in the intracellular Ca2+ concentration in altered gravity (microgravity and clinostating) evidence that Ca2+ signaling can play a fundamental role in biological effects of microgravity. Calcium as a second messenger is known to play a crucial role in stimulus-response coupling for many plant cellular signaling pathways. Its messenger functions are realized by transient changes in the cytosolic ion concentration induced by a variety of internal and external stimuli such as light, hormones, temperature, anoxia, salinity, and gravity. Although the first data on the changes in the calcium balance in plant cells under the influence of altered gravity have appeared in 80th, a review highlighting the performed research and the possible significance of such Ca2+ changes in the structural and metabolic rearrangements of plant cells in altered gravity is still lacking. In this paper, an attempt was made to summarize the available experimental results and to consider some hypotheses in this field of research. It is proposed to distinguish between cell gravisensing and cell graviperception; the former is related to cell structure and metabolism stability in the gravitational field and their changes in microgravity (cells not specialized to gravity perception), the latter is related to active use of a gravitational stimulus by cells presumebly specialized to gravity perception for realization of normal space orientation, growth, and vital activity (gravitropism, gravitaxis) in plants. The main experimental data concerning both redistribution of free Ca2+ ions in plant cell organelles and the cell wall, and an increase in the intracellular Ca2+ concentration under the influence of altered gravity are presented. Based on the gravitational decompensation hypothesis, the consequence of events occurring in gravisensing cells not specialized to gravity perception under altered gravity are considered in the following order: changes in the cytoplasmic membrane surface tension --> alterations in the physicochemical properties of the membrane --> changes in membrane permeability, --> ion transport, membrane-bound enzyme activity, etc. --> metabolism rearrangements --> physiological responses. An analysis of data available on biological effects of altered gravity at the cellular level allows one to conclude that microgravity environment appears to affect cytoskeleton, carbohydrate and lipid metabolism, cell wall biogenesis via changes in enzyme activity and protein expression, with involvement of regulatory Ca2+ messenger system. Changes in Ca2+ influx/efflux and possible pathways of Ca2+ signaling in plant cell biochemical regulation in altered gravity are discussed.     

Marangoni convection when the surface tension increases with the temperature in normal and low gravity conditions

Thermocapillary convection has been studied in n-heptanol aqueous solutions whose surface tension is increasing with the temperature.

The fluid was confined in a parallelipipedic enclosure and a thermal gradient was imposed parallel to the free liquid/gas interface. The motions induced by the thermocapillary forces have been studied under low gravity conditions during Texus sounding rocket experiments and during the Spacelab D1 mission.

The combined thermocapillary and buoyancy convection have been extensively studied during ground based experiments.

The influence of the aspect ratio and of the alcohol concentration were investigated. Detailed velocity field was determined at the steady state under normal gravity conditions by Laser Doppler Anemometry (LDA).

The aspect ratio was of 0.3 and the temperatures imposed to the lateral sides of the cell were respectively 45°C and 60°C. With these experimental conditions, two superposed contrarotative cells were observed with rapid motions in the surface from the cold to the hot side. This convective pattern was also observed during the normal and high gravity periods of parabolic flights but during the low gravity period of the parabola the motions stopped everywhere in the fluid even in the surface and reappeared immediatly at the pull out of the parabola.     

非等间距显式算法在重力波非线性传播数值模拟中的初步应用

采用3阶TVD型显式时间积分方法,建立了2维可压缩大气中重力波非线性传播的非等间距显式数值模式.对小振幅重力波传播过程的模拟结果表明,该模式能够很好地再现小振幅重力波的传播过程,并能保持能量守恒关系和各扰动量之间的相位关系,与线性重力波理论预测的结果吻合很好.对有限振幅重力波的模拟结果表明,与格点数相同的等间距网格中的模拟结果相比,采用非等间距网格能够以更高的分辨率模拟重力波的不稳定传播直到破碎的整个过程;在非等间距网格中的模拟结果与在加密一倍的等间距网格中的模拟结果相同,说明了用非等间距网格模拟重力波的饱和与破碎过程是正确的,并且采用非等间距网格能够大大减少计算量.      

Gravity as an obligatory factor in normal higher plant growth and development

Gravity may influence different aspects of plant activity. The present report deals with two questions: gravity as an ecological factor determining spatial orientation of plant growth; and second, a possible requirement for gravity in the process of normal growth, morphogenesis and generative development of plants.     

地面模拟静止微重力环境中导线先期着火特性研究

针对在微重力环境中运行的载人航天飞行器上的电缆和导线在工作时由于电流过载导致温度升高而引起着火的情况,提出了"功能模拟"实验原理,并且利用地面实验设备对微重力环境下导线的着火前期特性进行了功能模拟实验研究.通过实验,得到了在微重力情况下由于浮升力的减小使自然对流减弱导致电流过载时导线的热平衡温度高于地面正常重力情况,从而证明了这正是引起航天飞行器着火的潜在点火源.      

Directional solidification of complex-forming eutectic melt of the PbCl2-AgCl dielectric system under conditions of zero, normal and increased gravity

First results in the area of studying the influence of gravity field on the degree of ordering of directionally solified eutectict are presented. As the model complex-forming melts, PbCl₂ and its eutectic with AgCl was chosen. Directional solidification of the mentioned eutectic was realised under conditions of zero, normal and increased gravity. It was shown that increasing level of gravity results in a marked improvement of the degree of spacial ordering of the lamelar structure.     

Classification of gravity effects on “free” cells

When cell physiologists detect gravity related reactions of their objects it is often difficult to decide where the receptors for the observed effects are located. Answering this question is necessary for any further analysis of a detected gravity effect on cells. In previous papers we have discussed direct and indirect gravity effects in relation to the smallest functional units where the primary receptor, which interacts with gravity, is positioned inside and outside of such a unit, respectively. So, in a first approximation we can conclude that in a multicellular aquatic organism, which changes its metabolism in weightlessness, the primary receptors of gravity are located inside the cells of that organism. A special approach is necessary when free living cells, the density of which may be higher than the one of the (liquid) medium, or even cells living on a free surface are observed. In these two cases also indirect effects have to be taken into account, which will be demonstrated with the aid of the slime mold . Additionally the environment of the organisms can be changed directly and indirectly by gravity.     

基于流动沸腾气泡脱落行为的重力无关性分析

在流动沸腾现象中，气液两相密度差异导致重力对流动和传热性能产生很大影响，因此重力效应研究对于流动沸腾的航天应用具有重要意义.在对Bower-Klausner-Sathyanarayan重力无关准则（BKS准则）分析的基础上，提出其判据存在理论缺陷，不能正确反映重力效应.采用与BKS准则相同的气泡脱落模型，但忽略气泡沿加热管壁的滑动效应，重新计算常重力条件下不同流动方向起始沸腾阶段单气泡的脱落尺寸，归纳得到一个新的基于Fr（Froude数）的重力无关准则.该准则与实验结果符合更好，且与主导作用力准则基本相符.      

Magnetic levitation-based Martian and Lunar gravity simulator.

Missions to Mars will subject living specimens to a range of low gravity environments. Deleterious biological effects of prolonged exposure to Martian gravity (0.38 g), Lunar gravity (0.17 g), and microgravity are expected, but the mechanisms involved and potential for remedies are unknown. We are proposing the development of a facility that provides a simulated Martian and Lunar gravity environment for experiments on biological systems in a well controlled laboratory setting. The magnetic adjustable gravity simulator will employ intense, inhomogeneous magnetic fields to exert magnetic body forces on a specimen that oppose the body force of gravity. By adjusting the magnetic field, it is possible to continuously adjust the total body force acting on a specimen. The simulator system considered consists of a superconducting solenoid with a room temperature bore sufficiently large to accommodate small whole organisms, cell cultures, and gravity sensitive bio-molecular solutions. It will have good optical access so that the organisms can be viewed in situ. This facility will be valuable for experimental observations and public demonstrations of systems in simulated reduced gravity.