Degraded EEG response of the human brain in function of gravity levels by the method of chaotic attractor

The measurement of the influence of different gravity levels on the brain allows to explain how humans react to microgravity in space and to predict the adaptation capability of astronauts. Human electroencephalographic (EEG) signals were recorded during low and high gravity phases of three consecutive days of parabolic flights on the Caravelle aircraft in 1991. EEG signals were processed, using the method of correlation dimensions d of chaotic strange attractors. Results show clear differences between the three flights, with a general decrease over time in the attractor dimensions, a measure of the brain response to changing g levels. However, the dimension is not a one-to-one relation with g levels, as additional variations are observed. Two hypotheses are introduced, the "fatigue/stress" and the "g stress" hypotheses corresponding, respectively, to long-term fatigue accumulated over the three flights, and to short-term fatigue in response to change in g levels. The former explains the overall decrease of dimensions, the latter yields additional variations on shorter time scales. As the brain response degrades with time, at least six degraded modes were observed, explained by both short- and long-term fatigue.     

Representing space in a PDP network: Coarse allocentric coding can mediate metric and nonmetric spatial judgements

In one simulation, an artificial neural networkwas trained to rate the distances between pairsof cities on the map of Alberta, given onlyplace names as input. Distance ratings rangedfrom 0 (when the network rated the distancebetween a city and itself) to 10. The questionof interest was the nature of therepresentations developed by the network's sixhidden units after it successfully learned tomake the desired responses. Analyses indicatedthat the network used coarse allocentric codingto solve this problem. Each hidden unit couldbe described as occupying a position on the mapof Alberta, and each connection weight feedinginto a hidden unit was related to the distanceon the map between the hidden unit and one ofthe stimulus cities. On its own, a singlehidden unit's response was a relativelyinaccurate distance measure. However, bycombining all six hidden unit responses in acoarse coding scheme, accurate responses weregenerated by the network. In a secondsimulation, a second network was trained tomake similar judgements, but was trained toviolate the minimality constraint on metricspace when trained to judge the distancebetween a city and itself. An analysis of thisnetwork indicated that it too was using coarseallocentric coding.     

Vestibular tests in the selection of cosmonauts.

Vestibulo-vegetative disorders in cosmonauts and astronauts occurring during space flight compel otolaryngologists to search for vestibular tests enabling a precise evaluation of the activity of the vestibular apparatus and showing disposition to motion sickness. Otoneurological investigation of Polish candidates for cosmonaut status consisted of the following vestibular tests: caloric, rotatory, optokinetic, swinging torsion, statokinesimetric and vestibulo-vegetative. The value of various vestibular tests for aviation and space medicine is presented in this paper, taking into account the results of investigations of the equilibrium system with the group of pilots selected for space flight as well as extensive experience with candidates for the air service and also trained pilots and patients. The relatively frequent lack of correlation between the results of the applied tests, which renders difficult the proper evaluation of the equilibrium system, is emphasized in the paper. Finally, the results of investigations of acute habituation of the vestibular apparatus are discussed.     

An Artificial Neural Network That Uses Coarse Allocentric Coding of Direction to Represent Distances Between Locations in a Metric Space

An artificial neural network was trained to rate the distances between all possible pairs taken from a set of thirteen different cities on the map of Alberta. After learning to solve this problem, the internal structure of the network was analyzed. It was found that in spite of the fact that the network was trained to rate distances, the hidden units in the network were not sensitive to distance at all. Instead, it was found that each hidden unit could be located at a particular latitude and longitude on the map of Alberta, and that at this location each hidden unit was associated with a specific heading. Each hidden unit measured the bearing of each city relative to the hidden unit's heading, and when a stimulus was presented to the network, the hidden units combined the two city bearings and generated an activity level based on this combination. The output units of the network generated an accurate distance rating by combining the directional signals that were being computed by the hidden units. These results are discussed in terms of their implications for theories about cognitive maps, in particular the modularization of distance measurements from directional measurements.     

Biochemical and hormonal changes in endurance trained volunteers during and after exposure to bed rest and chronic hyperhydration.

The objective of this investigation was to assess the effect of a daily intake of fluid and salt supplementation on biochemical and hormonal changes in endurance trained volunteers aged 19-24 yrs during 30-day bed rest and during 15 days of post bed rest period. The studies were performed on 30 long distance runners aged 19-24 yrs who had a peak oxygen uptake of 66 ml/kg/min and had taken 14.5 km/day on average prior to their participation in the study. The volunteers were divided into three groups: the volunteers in the first group were under normal ambulatory conditions (control subjects); the second group subjected to bed rest alone unsupplemented (bed rested volunteers); the third group was submitted to bed rest and consumed daily 30 ml water/kg bodyweight and 0.1 g of sodium chloride (NaCl)/kg body weight (supplemented bed rested volunteers). The second and third groups of volunteers were kept under a rigorous bed rest regime for 30 days. During the pre bed rest period of 15 days, during the bed rest period of 30 days and during the post bed rest period of 15 days cyclic adenosine monophosphate, cyclic guanosine monophosphate, prostaglandins of pressor, prostaglandins depressor groups, renin activity in plasma and aldosterone in plasma and in urine were determined. We found that in bed rested volunteers without fluid and salt supplementation intake plasma renin activity and aldosterone in plasma and urine continued to increase during the bed rest period as plasma volume decreased. Moreover, in this group, cyclic nucleotides measured as an indicator of adrenosympathetic system activity increased and prostaglandins as local vasoactive substances decreased during the bed rest period. These variables returned toward the baselines in the post bed rest period as plasma volume deficit was restituted. On the other hand, the hormonal levels in the other two groups remained rather constant during the experimental period. We concluded that daily intake of fluid and salt supplementation may minimize the biochemical and hormonal changes in endurance trained volunteers dorm their exposure to bed rest conditions.     

The dynamics of blood biochemical parameters in cosmonauts during long-term space flights

Most of the previously obtained data on cosmonauts' metabolic state concerned certain stages of the postflight period. In this connection, all conclusions, as to metabolism peculiarities during the space flight, were to a large extent probabilistic. The purpose of this work was study of metabolism characteristics in cosmonauts directly during long-term space flights. In the capillary blood samples taken from a finger, by "Reflotron IV" biochemical analyzer, "Boehringer Mannheim" GmbH, Germany, adapted to weightlessness environments, the activity of GOT, GPT, CK, gamma-GT, total and pancreatic amylase, as well as concentration of hemoglobin, glucose, total bilirubin, uric acid, urea, creatinine, total, HDL- and LDL cholesterol, triglycerides had been determined. HDL/LDL-cholesterol ratio also was computed. The crewmembers of 6 main missions to the "Mir" orbital station, a total of 17 cosmonauts, were examined. Biochemical tests were carried out 30-60 days before launch, and in the flights different stages between the 25-th and the 423-rd days of flights. In cosmonauts during space flight had been found tendency to increase, in compare with basal level, GOT, GPT, total amylase activity, glucose and total cholesterol concentration, and tendency to decrease of CK activity, hemoglobin, HDL-cholesterol concentration, and HDL/LDL - cholesterol ratio. Some definite trends in variations of other determined biochemical parameters had not been found. The same trends of mentioned biochemical parameters alterations observed in majority of tested cosmonauts, allows to suppose existence of connection between noted metabolic alterations with influence of space flight conditions upon cosmonaut's body. Variations of other studied blood biochemical parameters depends on, probably, pure individual causes.     

Fluid electrolyte excretion during different hypokinetic body positions of trained subjects

The aim of this study was to evaluate the effect of different body positions on renal excretion of fluid and electrolytes after exposure to 364 days of decreased number of steps per day (hypokinesia, HK). The studies were performed on 18 endurance trained male volunteers aged 19-24 years who had an average of VO2max 67 ml/kg body/min. All volunteers were divided into three equal groups: the 1st group subjected to 12 h orthostatic position (OP) and 12 h clinostatic position (CP)/day, the 2nd group exposed to 8 h orthostatic position and 14 h clinostatic position/day, and the 3rd group submitted to 10 h orthostatic position and 16 h clinostatic position/day for 364 days. For the simulation of the hypokinetic effect all volunteers were kept under an average of 3000 steps/day for 364 days. Diuresis and the concentrations of sodium, potassium, chloride, calcium and magnesium as well as excretion of creatine were determined in 24-h urine samples. By the end of the hypokinetic period all volunteers, regardless of their body position during HK, manifested a significant increase in renal excretion of fluid and electrolytes as compared to prehypokinetic period values. It was concluded that prolonged restriction of motor activity induced a significant increase in renal excretion of fluid and electrolytes in endurance trained subjects regardless to their body position and duration thereof per day.     

Relationships between orientation, movement and posture in weightlessness: preliminary ethological observations

Weightlessness in man induces changes in astronaut orientations and consequently in his patterns of movements and postures. An ethological method has been used to describe the "overall" spontaneous behaviour of astronauts as seen from video recordings made during Space Flights. The work has consisted in analysing the relationships between orientation, movement and posture as an indication of a motor adaptative reorganization in such a situation. The results obtained lead us to consider three different aspects: (1) Orientation references. The astronaut orientates himself with reference to the Space Shuttle's internal structure; the increase of visual activity confirms the choice of the retinal vertical as frame of reference. (2) Motor coordination. The main data reveals a decrease in motor stereotypes by the diversity of motor acts observed and the importance of the link between orientation and posture described as follows: slightly inclined forward position, with legs flexed at about 135 degrees. (3) Cognitive references. There appears to be a new organization of the cognitive image of the body scheme, the missing vestibular information being supplied by peripheral vision instead which could play a role in the astronaut's perception of his own movement.     

Some aspects of psychophysiological support of crewmember's performance reliability in space flight

Crewmembers play an important role in ensuring the efficiency of "crew-spacecraft" system. However, despite of the fact that crewmembers are well trained and highly motivated persons, extreme flight factors may influence negatively on their reliability, and lead to human error occurrence. Therefore, working out methods of human error prevention is very significant to increase crewmember's performance reliability. Human error can occur in the operation of systems for a number of reasons. Within the framework of the present investigation, with use the data collected during "Mir" station missions, the significant (p<0.05) positive correlation of crewmembers errors (CE) frequency with their psychophysiological state (PPS), and work and rest schedule (WRS) intensity has been revealed. Differently, the higher WRS intensity, the crewmember's PPS is worse, and CE frequency is higher. This finding has been based on substantiations of the approach to human reliability management. Its essence will consist of the following: reducing WRS intensity, we thus can improve a crewmember's PPS and, accordingly, reduce CE frequency. This approach is discussed in the paper.     

Subgravity states: key to understanding the role of terrestrial gravity in human behaviour

The early orbital flights, although undertaken with considerable confidence, involved some uncertainty because of the impossibility of simulating under terrestrial conditions all of the conditions encountered in space. However, space-flight achievements by both the American astronauts and Soviet cosmonauts have firmly established that man, if appropriately selected, trained, and protected by suitable life-support systems, can perform efficiently for long periods of time in the hostile environment of space. We know that the side effects of vestibular origin pose important problems in space exploration, and the neurophysiological effects of any extensive, rapid adaptation processes in subgravity states have enabled a better understanding of man's compensatory capabilities. With the successful establishment of orbiting research laboratories, an unparalleled opportunity exists that will undoubtedly enable better understanding of the role played by gravity in normal terrestrial activity, not only as it affects our vestibular physiology, but also as it may or may not concern other systems and at different organizational levels in the body.     

Identification of coronal sources of the solar wind from solar images in the EUV spectral range

Methods of localizing coronal sources of the solar wind (SW), such as coronal holes, quasi-stationary fluxes from active regions, and transient sources associated with small-scale active phenomena are considered based on vacuum-ultraviolet (EUV) images of the corona at low solar activity during the initial period of the 24th solar cycle (2010). It is shown that a SW velocity profile can be calculated from the relative areas of coronal holes (CH) at the central part of the disk based on the images in the ranges of 193 and 171 Å. The images in the 193 Å describe the geometry of large HCs that represent sources of fast SW well. The images in 171 Å are a better visualization of small CHs, based on which the profile of a slow SW component was calculated to a high accuracy (up to 65 km/s). According to Hinode/EIS data of October 15, 2010, using the Doppler spectroscopy method at the streamer base over the active region 11112, the source of the outgoing plasma flux with the mean velocity of 17 km/s was localized in the magnetic field region with an intensity of less than 200 Gauss. According to the estimate, the density of the plasma flux from this source is an order of magnitude greater than the value required for explaining the distinction between the calculated and measured profiles of a slow SW velocity. For finding the transient SW component based on small-scale flare activity, SW parameters were analyzed for the periods of flares accompanied by coronal mass ejections (CMEs), and for the periods without flares, according to the data obtained in 2010 from the ACE and GOES satellites and by coronagraphs on the STEREO-A and -B spacecraft. The ion ratios C⁺⁶/C⁺⁵ and O⁺⁷/O⁺⁶ and the mean charge of Fe ions for periods with flares were shown to be shifted toward large values, suggesting the presence of a hot SW component associated with flare activity. A noticeable correlation between the maximum charge of Fe ions and the peak power of a flare, previously observed for flares of a higher class, was confirmed. The mean value of the SW flux density during the periods of flares was 30% higher than that in the periods without flares, which is possibly associated also with the growth of fluxes from other sources with an increasing solar activity level. Based on the example of a series of flares of October 13–14, 2010, it was supposed that transient SW fluxes from the weak flares at low solar activity can manifest themselves in the form of interplanetary ICME-transients.     

Rats in a transparent morris water maze use elemental and configural geometry of landmarks as well as distance to the pool wall

The aim of this study is to evaluate whatare the dimensions of a panorama of discretelandmarks that a rodent will store in order toreturn to a previously visited target. Ratswere trained to locate a hidden platform in acircular pool of clouded water set within aquasi-spherical enclosure. In order to find theplatform, they had to learn the geometricrelations between the platform and asurrounding set of three discrete landmarks,highly visible through the transparent wall ofthe pool. In test trials without a platform,the array of landmarks was so manipulated as todissociate the effect of actual distance to thelandmarks, of their angular separation, and oftheir apparent dimension. Animals were shown torely equally on angular separation and apparentdimension. The role of actual distance couldnot be definitely ascertained, as animals wereshown to additionally rely on the distance tothe pool wall in order to locate theplatform.     

INTERBALL-1 Observations of the Kilometric “Continuum” of the Earth's Magnetosphere

The electromagnetic radio-frequency emission of the inner region of the Earth's plasmasphere discovered recently by the GEOTAIL satellite [4] and referred to as the kilometric continuum was observed by the INTERBALL-1 satellite (1995–2000) in the 100–500 kHz band in the AKR-X experiment. During a period of low solar activity (1995–1997), this continuum was found leaving the inner plasmasphere at geocentric distances of 2–4R _E as isolated pencil-like (1°–6°) beams located in the magnetic equator plane. During a time of high solar activity (1999–2000), the occurrence of the emission was extremely rare (it was observed only at a considerable fall of this activity). If detected, at the same geocentric distances (2–4R _E) the continuum demonstrated a strongly variable and perturbed character, as well as a considerably larger extension of the beam over the geomagnetic latitude (10°–20° and more). In addition, quasi-periodic (QP) signals, similar to the observed QP emissions of Jupiter, were sometimes detected in this period. The probable nature of the observed features of the kilometric continuum is briefly discussed.     

Metabolic assessments during extra-vehicular activity

Extra-vehicular activity (EVA) has a significant role during extended space flights. It demonstrates that humans can survive and perform useful work outside the Orbital Space Stations (OSS) while wearing protective space suits (SS). When the International Space Station 'Alpha' (ISSA) is fully operational, EVA assembly, installation, maintenance and repair operations will become an everyday repetitive work activity in space. It needs new ergonomic evaluation of the work/rest schedule for an increasing of the labor amount per EVA hour. The metabolism assessment is a helpful method to control the productivity of the EVA astronaut and to optimize the work/rest regime. Three following methods were used in Russia to estimate real-time metabolic rates during EVA: 1. Oxygen consumption, computed from the pressure drop in a high pressure bottle per unit time (with actual thermodynamic oxygen properties under high pressure and oxygen leakage taken into account). 2. Carbon dioxide production, computed from CO2 concentration at the contaminant control cartridge and gas flow rate in the life support subsystem closed loop (nominal mode) or gas leakage in the SS open loop (emergency mode). 3. Heat removal, computed from the difference between the temperatures of coolant water or gas and its flow rate in a unit of time (with assumed humidity and wet oxygen state taken into account). Comparison of heat removal values with metabolic rates enables us to determine the thermal balance during an operative medical control of EVA at "Salyut-6", "Salyut-7" and "Mir" OSS. Complex analysis of metabolism, body temperature and heat rate supports a differential diagnosis between emotional and thermal components of stress during EVA. It gives a prognosis of human homeostasis during EVA. Available information has been acquired into an EVA data base which is an effective tool for ergonomical optimization.     

Dynamics of the 0.3–100 MeV Proton Energy Spectra in the Inner Heliosphere in Quiet Periods of 1974–1991

Variations of the proton spectra in the 0.3–100 MeV energy range based on the data of various instruments installed onboard the IMP-8 satellite are studied for very quiet, quiet, and quasi-stable solar activity periods during the years 1974–1991. As many as 118 spectra were approximated by two power laws: the left-hand and galactic branches of the spectrum were fitted by the AE ^– function and a dependence of the CE type, respectively, the sum J(E) = AE ^– + CE providing the total spectrum. It is shown that the spectra vary within a solar cycle with a shift of the minimum energy (E _min) to higher energies with increasing solar activity. It follows from the relations between the spectrum parameters thus obtained that, in particular periods of time, an increase (decrease) of the particle flux in the low-energy branch of the spectrum and an intensification (depression) of the GCR particle flux modulation take place simultaneously. This is manifested in a shift of the spectrum parallel to the energy axis. The study of the spectra in the most quiet time during three successive solar minima have shown that low-energy (0.3–10 MeV) protons, as well as GCR, are subject to the 22-year variation in the solar magnetic cycle.     

基于神经网络的潜在通路分析

针对传统潜在通路分析过程复杂、劳动量大的缺陷，提出了基于神经网络的潜在通路分析。神经网络的输入为系统元件的定性状态组合，输出为预测实现功能组合。利用元件与设计功能之间的关系，形成神经网络训练样本。经过训练后，神经网络预测所有元件状态组合实现的功能，然后通过与设计功能的比较，确定电路的潜在通路。经仿真验证，此方法进行潜在通路分析时的正确率达到了92％，而且分析的工作量比较小。     

基于脑机交互接口的遥控小车控制平台设计

本文介绍了BCI（脑机交互接口）的基本概念和研究现状,并通过对脑电信号性质的分析,选取适合BCI系统控制平台所需的脑电信号特征信息,对该信息放大、处理、提取和分类识别后,转化成BCI系统的所需控制命令,实现对外部设备的通信与控制。     

Effect of weightlessness on sympathetic-adrenomedullary activity of rats.

Three cosmic experiments were performed in which rats spent 18-20 days in space on board the biosatellites "COSMOS 782", "COSMOS 936" and "COSMOS 1129". The following indicators of the sympathetic-adrenomedullary system (SAS) activity were measured: tissue and plasma catecholamines (CA), CA-synthesizing enzymes--tyrosine hydroxylase (TH), dopamine-beta-hydroxylase (DBH), phenylethanolamine-N-methyltransferase (PNMT)--as well as CA-degrading enzymes-monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT). Adrenal epinephrine (EPI) and norepinephrine (NE) as well as CA-synthesizing and degrading enzymes were not significantly changed in the animals after flight on COSMOS 782. On the other hand, a significant increase was found in heart CA, the indicator which is usually decreased after stress. 26 days after landing all values were at control levels. The results obtained, compared to our previous stress experiments on Earth, suggest that prolonged weightlessness does not appear to be a pronounced stressful stimulus for the SAS. Heart and plasma CA, mainly NE, were increased both in the group living in the state of weightlessness and the group living in a centrifuge and exposed to artificial gravitation 1 g (COSMOS 936), suggesting again that prolonged weightlessness is not an intensive stressful stimulus for the SAS. The animals exposed after space flight on COSMOS 1129 to repeated immobilization stress on Earth showed a significant decrease of adrenal EPI and an expressive increase of adrenal TH activity compared to stressed animals which were not in space. Thus, the results corroborate that prolonged state of weightlessness during space flight though not representing by itself an intensive stressful stimulus for the sympathetic-adrenomedullary system, was found to potentiate the response of "cosmic rats" to stress exposure after return to Earth.     

Sources and Losses of Energetic Electrons at Low Altitudes from Satellite Data

Fluxes and differential spectra of 0.04–2.0 MeV electrons at low altitudes in the Earth's magnetosphere are considered in comparison with the model spectra AE-8 MAX and AE-8 MIN. Possible causes of the discrepancy between the observational and model spectra are discussed. The coefficients of radial diffusion at various L-shells are estimated for the maximum of solar activity (using the Interkosmos-19 data) and for the minimum of solar activity (using the Kosmos-1686 data) and are derived from the model AE-8. A quantitative evaluation of the electron yield from radial diffusion at low L shells is derived. Ionization losses, Coulomb angle scattering, and resonant wave–particle interaction are considered as the loss mechanisms. A calculation of these losses at the low L-shells is given. The electron distribution at low L-shells is best fitted by a combination of dissipative terms from different models: Coulomb scattering dominates at the lower L-shells (L = 1.2–1.4) and the resonant wave–particle interaction controls the radiation belt maximum and the gap (L = 1.4–2.0).     

Function-morphological investigations of fish inner ear otoliths as basis for interpretation of human space sickness

In man, altered gravity may lead to a vestibular dysfunction causing space motion sickness. A hypothesis was developed, according to which asymmetric inner ear statoliths might be the morphological basis of space sickness. The animal model, fish, revealed further information: inner ear "stone" (otolith) growth is dependent on the amplitude and the direction of gravity, regulated by a negative feedback mechanism. The present study was focused on the question, where the regulation centre of adaptive otolith growth may be situated. Therefore, the vestibular nerve was unilaterally transected in neonate swordtail fish (Xiphophorus helleri). As growth marker, the calcium tracer alizarin-complexone was used. It was found that otolith growth had ceased on the operated head sides indicating that the brain is significantly involved in regulating otolith growth. About 2 weeks after nerve transection, otoliths had regained normal growth, probably due to nerve regeneration. Concerning fish, it has now to be tested, if this regeneration is affected by altered gravity, e.g. in a long-term experiment on the International Space Station. Regarding mammals, it has to be proved if asymmetric statoliths are the basis of kinetosis and whether or not the mammalian brain has an effect on statolith growth in the course of compensating altered gravity.