| 用于荧光细胞观察的制冷CCD成像系统 |
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| 引用本文： | 樊尚春,关铭,郑德智,邢维巍,刘长庭,陈广飞. 用于荧光细胞观察的制冷CCD成像系统[J]. 航天器环境工程, 2010, 27(2): 202-205. DOI: 10.3969/j.issn.1673-1379.2010.02.016 |
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| 作者姓名： | 樊尚春 关铭 郑德智 邢维巍 刘长庭 陈广飞 |
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| 作者单位： | 北京航空航天大学,仪器科学与光电工程学院,北京,100191;中国人民解放军总医院,呼吸科,北京,100853;中国人民解放军总医院,医学工程保障中心,北京,100853 |
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| 基金项目： | 国家863项目(项目编号:2008AA12A20) |
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| 摘 要： | 细胞成像技术是研究细胞运动、分裂和凋亡的必要手段,所以荧光条件下的细胞成像技术显得尤为重要。为满足荧光细胞观察对微弱光信号的检测和成像的要求,文章通过结构和电路设计,研制了一种用于荧光细胞观察的制冷CCD成像系统。通过分析各组件的技术特点,设计了高效制冷结构,提高了细胞荧光观察输出图像质量。
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| 关 键 词： | 荧光细胞观察 生物荧光技术 CCD图像传感器 半导体制冷 |
| 收稿时间： | 2009-09-18 |
A cooling CCD image system for fluorescence cell observation |
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| Fan Shangchun,Guan Ming,Zheng Dezhi,Xing Weiwei,Liu Changting and Chen Guangfei. A cooling CCD image system for fluorescence cell observation[J]. Spacecraft Environment Engineering, 2010, 27(2): 202-205. DOI: 10.3969/j.issn.1673-1379.2010.02.016 |
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| Authors: | Fan Shangchun Guan Ming Zheng Dezhi Xing Weiwei Liu Changting Chen Guangfei |
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| Affiliation: | 1.School of Instrument Science and Opto-electronics Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China2.Department of Respiration, General Hospital of PLA, Beijing 100853, China3.Centre of Medical Engineering Ensuring, General Hospital of PLA, Beijing 100853, China |
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| Abstract: | As an important tool in the studies of the mobility,division and fate of cells,the cell image technology is very useful under the condition of fluorescence.In order to achieve signal detection in weak light level,a cooling CCD image system for fluorescence cell observation is developed,complete with the design of structure and circuits,which consists of CCD chips used for medical imaging,CCD drive circuit based on FPGA and cooling device with TEC.By analyzing the characteristics of modules,an efficient cool... |
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| Keywords: | fluorescence cell observation bioluminescence CCD image sensor semiconductor cooling |
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